Symbol:
Fscn2
Name:
fascin actin-bundling protein 2, retinal
RGD ID:
1308941
Description:
Predicted to enable actin filament binding activity. Predicted to be involved in actin filament bundle assembly; cell migration; and establishment or maintenance of cell polarity. Predicted to act upstream of or within eye photoreceptor cell development. Predicted to be located in stereocilium. Predicted to be active in actin cytoskeleton and cytoplasm. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 30. Orthologous to human FSCN2 (fascin actin-bundling protein 2, retinal); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
fascin homolog 2, actin-bundling protein, retinal; fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus); fascin-2; LOC303741
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
FSCN2 (fascin actin-bundling protein 2, retinal)
HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Fscn2 (fascin actin-bundling protein 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Fscn2 (fascin actin-bundling protein 2, retinal)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
FSCN2 (fascin actin-bundling protein 2, retinal)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
FSCN2 (fascin actin-bundling protein 2, retinal)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Fscn2 (fascin actin-bundling protein 2, retinal)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
FSCN2 (fascin actin-bundling protein 2, retinal)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
FSCN2 (fascin actin-bundling protein 2, retinal)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Fscn2 (fascin actin-bundling protein 2, retinal)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
FSCN1 (fascin actin-bundling protein 1)
HGNC
OrthoDB
Homo sapiens (human):
BBX (BBX high mobility group box domain containing)
HGNC
OMA
Alliance orthologs 3
Homo sapiens (human):
FSCN2 (fascin actin-bundling protein 2, retinal)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Fscn2 (fascin actin-bundling protein 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
fscn2a (fascin actin-bundling protein 2a, retinal)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
fscn2b (fascin actin-bundling protein 2b, retinal)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
sn
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
fscn2
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 10 106,121,038 - 106,139,683 (+) NCBI GRCr8 mRatBN7.2 10 105,634,783 - 105,641,322 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 10 105,634,783 - 105,641,322 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 10 110,739,192 - 110,745,719 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 10 110,202,211 - 110,208,738 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 10 105,555,265 - 105,561,804 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 10 109,528,307 - 109,540,675 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 10 109,533,487 - 109,540,026 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 10 109,128,055 - 109,134,594 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 10 109,789,092 - 109,795,631 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 10 109,803,763 - 109,810,072 (+) NCBI Celera 10 104,180,130 - 104,186,669 (+) NCBI Celera Cytogenetic Map 10 q32.3 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Fscn2 Rat (+)-catechin multiple interactions ISO FSCN2 (Homo sapiens) 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of FSCN2 mRNA CTD PMID:24763279 Fscn2 Rat 17beta-estradiol multiple interactions ISO FSCN2 (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FSCN2 mRNA CTD PMID:20823114 Fscn2 Rat 2,2',5,5'-tetrachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:23829299 Fscn2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO FSCN2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of FSCN2 mRNA CTD PMID:22574217 Fscn2 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of FSCN2 mRNA CTD PMID:27913140 and PMID:33387578 Fscn2 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Fscn2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of FSCN2 mRNA CTD PMID:27913140 Fscn2 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO FSCN2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of FSCN2 mRNA CTD PMID:27913140 Fscn2 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of FSCN2 mRNA CTD PMID:24780913 Fscn2 Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of FSCN2 mRNA CTD PMID:25825206 Fscn2 Rat benzo[a]pyrene decreases methylation ISO FSCN2 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of FSCN2 promoter CTD PMID:27901495 Fscn2 Rat benzo[a]pyrene affects methylation ISO FSCN2 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of FSCN2 exon CTD PMID:27901495 Fscn2 Rat bis(2-ethylhexyl) phthalate decreases methylation ISO Fscn2 (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased methylation of FSCN2 gene CTD PMID:34319233 Fscn2 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of FSCN2 mRNA CTD PMID:25181051 Fscn2 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of FSCN2 mRNA CTD PMID:34947998 Fscn2 Rat bisphenol A increases methylation ISO Fscn2 (Mus musculus) 6480464 bisphenol A results in increased methylation of FSCN2 promoter CTD PMID:27312807 Fscn2 Rat bucladesine multiple interactions ISO FSCN2 (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FSCN2 mRNA CTD PMID:20823114 Fscn2 Rat chlorpyrifos multiple interactions EXP 6480464 [Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of FSCN2 mRNA CTD PMID:27905518 Fscn2 Rat chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of FSCN2 mRNA CTD PMID:27905518 Fscn2 Rat cisplatin decreases expression ISO FSCN2 (Homo sapiens) 6480464 Cisplatin results in decreased expression of FSCN2 mRNA CTD PMID:27392435 Fscn2 Rat cisplatin affects response to substance EXP 6480464 FSCN2 protein affects the susceptibility to Cisplatin CTD PMID:27989596 Fscn2 Rat cisplatin multiple interactions EXP 6480464 [CTNNA1 protein affects the susceptibility to Cisplatin] which results in decreased expression of FSCN2 protein more ... CTD PMID:27989596 Fscn2 Rat cisplatin multiple interactions ISO FSCN2 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of FSCN2 mRNA CTD PMID:27392435 Fscn2 Rat decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of FSCN2 mRNA CTD PMID:23640034 Fscn2 Rat dichloroacetic acid increases expression ISO Fscn2 (Mus musculus) 6480464 Dichloroacetic Acid results in increased expression of FSCN2 mRNA CTD PMID:28962523 Fscn2 Rat dioxygen increases expression ISO FSCN2 (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of FSCN2 mRNA CTD PMID:26516004 Fscn2 Rat endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of FSCN2 mRNA CTD PMID:29391264 Fscn2 Rat Ethylenethiourea decreases expression EXP 6480464 Ethylenethiourea results in decreased expression of FSCN2 mRNA CTD PMID:27905518 Fscn2 Rat Ethylenethiourea multiple interactions EXP 6480464 [Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of FSCN2 mRNA CTD PMID:27905518 Fscn2 Rat fenvalerate increases expression EXP 6480464 fenvalerate results in increased expression of FSCN2 mRNA CTD PMID:30307764 Fscn2 Rat glycidol increases expression EXP 6480464 glycidol results in increased expression of FSCN2 mRNA CTD PMID:24395379 Fscn2 Rat latrunculin A multiple interactions EXP 6480464 latrunculin A affects the reaction [FSCN2 protein inhibits the reaction [CTNNA1 protein affects the susceptibility to Cisplatin]] CTD PMID:27989596 Fscn2 Rat manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of FSCN2 mRNA CTD PMID:28801915 Fscn2 Rat medroxyprogesterone acetate multiple interactions ISO FSCN2 (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FSCN2 mRNA CTD PMID:20823114 Fscn2 Rat N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of FSCN2 mRNA CTD PMID:28801915 Fscn2 Rat PCB138 decreases expression EXP 6480464 2 more ... CTD PMID:23829299 Fscn2 Rat sunitinib increases expression ISO FSCN2 (Homo sapiens) 6480464 Sunitinib results in increased expression of FSCN2 mRNA CTD PMID:31533062 Fscn2 Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of FSCN2 mRNA CTD PMID:34492290 Fscn2 Rat titanium dioxide decreases expression ISO Fscn2 (Mus musculus) 6480464 titanium dioxide results in decreased expression of FSCN2 mRNA CTD PMID:29264374 Fscn2 Rat trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of FSCN2 mRNA CTD PMID:33387578 Fscn2 Rat triphenyl phosphate affects expression ISO FSCN2 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of FSCN2 mRNA CTD PMID:37042841 Fscn2 Rat triptonide increases expression ISO Fscn2 (Mus musculus) 6480464 triptonide results in increased expression of FSCN2 mRNA CTD PMID:33045310 Fscn2 Rat valproic acid increases methylation ISO FSCN2 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of FSCN2 gene CTD PMID:29154799
Fscn2 (Rattus norvegicus - Norway rat)
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 10 106,121,038 - 106,139,683 (+) NCBI GRCr8 mRatBN7.2 10 105,634,783 - 105,641,322 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 10 105,634,783 - 105,641,322 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 10 110,739,192 - 110,745,719 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 10 110,202,211 - 110,208,738 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 10 105,555,265 - 105,561,804 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 10 109,528,307 - 109,540,675 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 10 109,533,487 - 109,540,026 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 10 109,128,055 - 109,134,594 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 10 109,789,092 - 109,795,631 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 10 109,803,763 - 109,810,072 (+) NCBI Celera 10 104,180,130 - 104,186,669 (+) NCBI Celera Cytogenetic Map 10 q32.3 NCBI
FSCN2 (Homo sapiens - human)
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 17 81,515,062 - 81,537,130 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 17 81,528,377 - 81,537,130 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 17 79,495,403 - 79,504,156 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 17 77,110,012 - 77,114,632 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 17 77,110,016 - 77,114,631 NCBI Celera 17 76,139,079 - 76,148,244 (+) NCBI Celera Cytogenetic Map 17 q25.3 NCBI HuRef 17 74,944,167 - 74,951,874 (+) NCBI HuRef CHM1_1 17 79,581,654 - 79,590,360 (+) NCBI CHM1_1 T2T-CHM13v2.0 17 82,430,273 - 82,454,442 (+) NCBI T2T-CHM13v2.0
Fscn2 (Mus musculus - house mouse)
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 11 120,250,991 - 120,258,999 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 11 120,252,360 - 120,258,994 (+) Ensembl GRCm39 Ensembl GRCm38 11 120,360,165 - 120,368,173 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 11 120,361,534 - 120,368,168 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 11 120,222,848 - 120,229,487 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 11 120,177,624 - 120,184,261 (+) NCBI MGSCv36 mm8 Celera 11 132,096,284 - 132,102,924 (+) NCBI Celera Cytogenetic Map 11 E2 NCBI cM Map 11 84.08 NCBI
Fscn2 (Chinchilla lanigera - long-tailed chinchilla)
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955506 1,526,830 - 1,533,775 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955506 1,526,830 - 1,533,775 (-) NCBI ChiLan1.0 ChiLan1.0
FSCN2 (Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 19 98,111,412 - 98,126,571 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 17 103,013,967 - 103,024,231 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 17 75,974,971 - 75,993,275 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 17 81,687,051 - 81,694,823 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 17 81,687,051 - 81,694,823 (+) Ensembl panpan1.1 panPan2
FSCN2 (Canis lupus familiaris - dog)
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 9 616,088 - 622,152 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 9 617,609 - 621,882 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 9 1,218,766 - 1,224,987 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 9 1,210,196 - 1,216,414 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 9 1,211,869 - 1,216,141 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 9 1,234,897 - 1,241,112 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 9 1,360,741 - 1,366,958 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 9 1,440,630 - 1,446,849 (-) NCBI UU_Cfam_GSD_1.0
Fscn2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024405602 1,216,619 - 1,227,828 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936594 5,184,628 - 5,191,985 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936594 5,184,133 - 5,195,340 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
FSCN2 (Sus scrofa - pig)
Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 12 1,300,055 - 1,309,778 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 12 1,300,286 - 1,311,562 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 12 1,143,345 - 1,156,961 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
FSCN2 (Chlorocebus sabaeus - green monkey)
Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 16 73,472,582 - 73,482,440 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 16 73,474,519 - 73,481,967 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666077 44,854,818 - 44,864,455 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Fscn2 (Heterocephalus glaber - naked mole-rat)
.
Predicted Target Of
Count of predictions: 93 Count of miRNA genes: 86 Interacting mature miRNAs: 91 Transcripts: ENSRNOT00000054975 Prediction methods: Microtar, Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
7387312 Bw125 Body weight QTL 125 3 0.0047 retroperitoneal fat pad mass (VT:0010430) retroperitoneal fat pad weight (CMO:0000356) 10 64890616 107211142 Rat 12880384 Cm107 Cardiac mass QTL 107 0.001 heart mass (VT:0007028) heart wet weight to body weight ratio (CMO:0002408) 90404397 107211142 Rat 12880385 Cm108 Cardiac mass QTL 108 0.001 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 90404397 107211142 Rat 1354641 Bvd2 Brain ventricular dilatation QTL 2 6.36 0.001 brain ventricle morphology trait (VT:0000822) hydrocephalus severity score (CMO:0001881) 10 93223816 107057807 Rat 2317029 Aia19 Adjuvant induced arthritis QTL 19 2.98 joint integrity trait (VT:0010548) left rear ankle joint diameter (CMO:0002149) 10 66978955 107211142 Rat 2303589 Bw87 Body weight QTL 87 2 body mass (VT:0001259) body weight (CMO:0000012) 10 81285008 107211142 Rat 12880396 Am13 Aortic mass QTL 13 0.001 aorta mass (VT:0002845) aorta weight to aorta length to body weight ratio (CMO:0002722) 10 90404397 107211142 Rat 61449 Ciaa2 CIA Autoantibody QTL 2 7.1 blood autoantibody amount (VT:0003725) calculated serum anti-type 2 collagen antibody titer (CMO:0001279) 10 63221094 107211142 Rat 12880398 Kidm67 Kidney mass QTL 67 0.001 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 10 90404397 107211142 Rat 61387 Bp1 Blood pressure QTL 1 5.1 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 10 51770177 107211142 Rat 2317039 Aia6 Adjuvant induced arthritis QTL 6 4.31 joint integrity trait (VT:0010548) right rear ankle joint diameter (CMO:0002150) 10 66978955 107211142 Rat 12880395 Cm109 Cardiac mass QTL 109 0.001 heart right ventricle mass (VT:0007033) heart right ventricle weight to body weight ratio (CMO:0000914) 10 90404397 107211142 Rat 1579915 Bp280 Blood pressure QTL 280 0.001 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 10 90404397 107211142 Rat 61396 Bp9 Blood pressure QTL 9 4.8 0.0001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 10 68420376 107211142 Rat 2298548 Neuinf7 Neuroinflammation QTL 7 3.4 nervous system integrity trait (VT:0010566) spinal cord RT1-B protein level (CMO:0002132) 10 72224939 107211142 Rat 1302404 Cia27 Collagen induced arthritis QTL 27 2.6 0.0045 joint integrity trait (VT:0010548) experimental arthritis severity measurement (CMO:0001459) 10 76452683 107211142 Rat 2317754 Glom25 Glomerulus QTL 25 3.5 urine protein amount (VT:0005160) urine protein level (CMO:0000591) 10 82685200 107211142 Rat 634320 Niddm49 Non-insulin dependent diabetes mellitus QTL 49 4.41 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) 10 88539139 107211142 Rat 70171 Cari1 Carrageenan-induced inflammation QTL 1 4.9 0.0005 hypodermis integrity trait (VT:0010550) inflammatory exudate volume (CMO:0001429) 10 53797385 107211142 Rat 1331791 Cm31 Cardiac mass QTL 31 3.84606 heart mass (VT:0007028) heart wet weight (CMO:0000069) 10 29299504 107211142 Rat 10450498 Bp384 Blood pressure QTL 384 0.002 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 10 67750049 107211142 Rat 4889492 Pancm2 Pancreatic morphology QTL 2 3.2 pancreatic beta cell morphology trait (VT:0005217) ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814) 10 76748906 107211142 Rat 6893366 Bw106 Body weight QTL 106 0.3 0.47 body mass (VT:0001259) body weight (CMO:0000012) 10 70199100 107211142 Rat 10450493 Bp382 Blood pressure QTL 382 0.002 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 10 94759759 107211142 Rat 1578672 Bmd16 Bone mineral density QTL 16 6.2 femur mineral mass (VT:0010011) compact volumetric bone mineral density (CMO:0001730) 10 96703043 107057807 Rat 2313103 Bss80 Bone structure and strength QTL 80 2 0.0001 tibia strength trait (VT:1000284) tibia midshaft endosteal cross-sectional area (CMO:0001716) 10 62057807 107057807 Rat 2293646 Bss25 Bone structure and strength QTL 25 10.96 0.0001 femur morphology trait (VT:0000559) femur cross-sectional area (CMO:0001661) 10 69738412 107211142 Rat 2300172 Bmd57 Bone mineral density QTL 57 9.8 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 10 69738412 107211142 Rat 70193 Mcs7 Mammary carcinoma susceptibility QTL 7 2.38 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 10 72224939 107211142 Rat 2313105 Bss79 Bone structure and strength QTL 79 1.8 0.0001 tibia size trait (VT:0100001) tibia midshaft cross-sectional area (CMO:0001717) 10 62057807 107057807 Rat 61363 Oia3 Oil induced arthritis QTL 3 0.001 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 10 87307617 107211142 Rat 2292438 Bp311 Blood pressure QTL 311 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 10 76246085 107211142 Rat 2316949 Gluco60 Glucose level QTL 60 3.7 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 10 14487011 107057807 Rat 2292436 Bp310 Blood pressure QTL 310 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 10 94759759 107211142 Rat 724530 Bp149 Blood pressure QTL 149 0.0001 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 10 90627439 107211142 Rat 1300137 Bp186 Blood pressure QTL 186 3.57 arterial blood pressure trait (VT:2000000) blood pressure time series experimental set point of the baroreceptor response (CMO:0002593) 10 90627439 107057807 Rat 631538 Oia5 Oil induced arthritis QTL 5 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 10 87055121 107211142 Rat 1642980 Bp300 Blood pressure QTL 300 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 10 68383129 107211142 Rat 2293663 Bss33 Bone structure and strength QTL 33 9.34 0.0001 femur strength trait (VT:0010010) femur midshaft polar moment of inertia (CMO:0001669) 10 69738412 107211142 Rat 1578663 Bss18 Bone structure and strength QTL 18 3.6 femur width (VT:1000666) femoral neck width (CMO:0001695) 10 96703043 107057807 Rat
RH134306
Rat Assembly Chr Position (strand) Source JBrowse GRCr8 10 106,139,278 - 106,139,552 (+) Marker Load Pipeline mRatBN7.2 10 105,640,917 - 105,641,191 (+) MAPPER mRatBN7.2 Rnor_6.0 10 109,539,622 - 109,539,895 NCBI Rnor6.0 Rnor_5.0 10 109,134,190 - 109,134,463 UniSTS Rnor5.0 RGSC_v3.4 10 109,795,227 - 109,795,500 UniSTS RGSC3.4 Celera 10 104,186,265 - 104,186,538 UniSTS Cytogenetic Map 10 q32.3 UniSTS
RH138456
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 10 105,638,822 - 105,638,964 (+) MAPPER mRatBN7.2 Rnor_6.0 10 109,537,527 - 109,537,668 NCBI Rnor6.0 Rnor_5.0 10 109,132,095 - 109,132,236 UniSTS Rnor5.0 RGSC_v3.4 10 109,793,132 - 109,793,273 UniSTS RGSC3.4 Celera 10 104,184,170 - 104,184,311 UniSTS Cytogenetic Map 10 q32.3 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
109
70
69
38
25
38
6
197
97
89
45
59
31
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Ensembl Acc Id:
ENSRNOT00000054975 ⟹ ENSRNOP00000051858
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 10 105,634,783 - 105,641,322 (+) Ensembl Rnor_6.0 Ensembl 10 109,533,487 - 109,540,026 (+) Ensembl
RefSeq Acc Id:
NM_001107072 ⟹ NP_001100542
RefSeq Status:
PROVISIONAL
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 10 106,133,144 - 106,139,683 (+) NCBI mRatBN7.2 10 105,634,783 - 105,641,322 (+) NCBI Rnor_6.0 10 109,533,487 - 109,540,026 (+) NCBI Rnor_5.0 10 109,128,055 - 109,134,594 (+) NCBI RGSC_v3.4 10 109,789,092 - 109,795,631 (+) RGD Celera 10 104,180,130 - 104,186,669 (+) RGD
Sequence:
CACAAGACAGAGGGAGCTGACTCTGAGGCAGGGAGTGTCCATGTTGCTGGCTAGGCTTGGGAGCCAAGGGCCAGATAAACAGATCTGGGCCTCAGGGGGGGCTACAGGCCCCCTGAACACTCAGAGAG AGCTCCCTGGACCCCTGAAGCAACTTGGCTAGTCTCAAAGATGCCAACCAACGGCTTGCACCAGGTGCTGAAGATCCAGTTTGGCCTTGTGAACGATGCCGACCGCTACCTCACGGCTGAGAGCTTTG GCTTCAAGGTCAACGCTTCCGCAGCCAGCCTCAAGAGGAAGCAGATATGGGTCCTGGAGCCTGACCCAGGGCAGGGCACTGCTGTGCTGTTTCGCAGCAGCCACCTAGGCCGCTACCTGTCGGCAGAA GAAGATGGGCGCGTGGCCTGTGAGATGGATCACCCGGGCCGTGACTGTCGCTTCTTGGTCTTGCCGCAGCCTGACGGGCGCTGGGTGCTGCAGTCAGAGCCACACGGCCGCTTCTTTGGTGGCGTTGA GGACCGACTGTCCTGCTTTGCTACGGCCATCTCCCCGGCAGAGCTGTGGACCGTACACCTGGCCATCCACCCACAGGCTCACTTGCTGAGTGTGAGCCGCCGGCGCTACGTGCACCTGTGCCTTCAGG AGGACGAGATGGCGGCAGATGGTGACATGCCGTGGGGTGTGGACGCACTGCTCACCCTCATTTTCCAGAGCAGGCGGTACTGCCTCAAGTCTTATGACAGCCGCTACCTTCGAAGTGATGGCCGCCTT GTCTGGGAGCCTGAAGCCCATGCCTGCTACACACTGGAGTTCAAGGCAGGCAAGCTGGCCTTCAAGGACTGTGACGGCCGATACCTGGCACCTGTGGGGCCTGCCGGCACGCTTAAGGCTGGCCGAAA CACGAGGCCCGGCAAGGATGAACTCTTCGACCTGGAGCAGAGTCACCCACAGGTGGTACTGGTAGCTGCCAACCACCGCTACGTCTCTGTGAGGCAAGGAATCAATGTCTCAGCCAATCAGGATGAAG AACTGGACCATGAGACATTCCTAATGCAAATCGACCAGGAGACAAAGAAGTGTACTTTCTATTCCAGCACTGGGGGCTACTGGACCTTGGTCACTCACGGGGGCATTCAGGCCACAGCCACGCAAGTT TCTGCCAACACCATGTTTGAAATAGAATGGCACGGCCGGCGGGTGGCACTTAAAGCCAGCAATGGGCGTTATGTGTGCATGAAGAAGAATGGGCAGCTGGCTGCTATCAGTGACTTTGTGGGTGAGGA CGAGTTATTCATCCTCAAACTCATCAACCGACCCATCCTGGTGCTCCGTGGCCTGGATGGCTTTGTGTGCCACCGCCGAGGCTCCAACCAGCTGGACACCAACCGCTCCACCTACGATGTCTTCCACC TGAGCTTCAGGGATGGCGCCTATCAAATCAGAGGCCGTGGAGGTGGGTTCTGGTACACTGGGAGCCATGGAAGTGTGTGCAGCGATGGTGACTTGGCGGAGGATTTCCTCTTCGAGTTCCGAGAGCGT GGCCGTTTGGCCATCCGTGCCCTCAGTGGCAAGTACCTGCGTGGAGGTGCCTCAGGGCTGCTGCGTGCTGACGCGGACCTGCCTACGGGGGAAGCTCTCTGGGAATATTGAGGACTCACAGGGGGTCA ACCCCAGAGCCAACCTACCCAGCATTAAACCTTTGTTGCAGAGTTG
hide sequence
RefSeq Acc Id:
XM_063269251 ⟹ XP_063125321
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 10 106,121,184 - 106,139,682 (+) NCBI
RefSeq Acc Id:
XM_063269252 ⟹ XP_063125322
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 10 106,121,038 - 106,139,682 (+) NCBI
RefSeq Acc Id:
XM_063269253 ⟹ XP_063125323
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 10 106,133,312 - 106,139,682 (+) NCBI
RefSeq Acc Id:
NP_001100542 ⟸ NM_001107072
- UniProtKB:
D3ZX02 (UniProtKB/TrEMBL), A6HLC3 (UniProtKB/TrEMBL)
- Sequence:
MPTNGLHQVLKIQFGLVNDADRYLTAESFGFKVNASAASLKRKQIWVLEPDPGQGTAVLFRSSHLGRYLSAEEDGRVACEMDHPGRDCRFLVLPQPDGRWVLQSEPHGRFFGGVEDRLSCFATAISPA ELWTVHLAIHPQAHLLSVSRRRYVHLCLQEDEMAADGDMPWGVDALLTLIFQSRRYCLKSYDSRYLRSDGRLVWEPEAHACYTLEFKAGKLAFKDCDGRYLAPVGPAGTLKAGRNTRPGKDELFDLEQ SHPQVVLVAANHRYVSVRQGINVSANQDEELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIQATATQVSANTMFEIEWHGRRVALKASNGRYVCMKKNGQLAAISDFVGEDELFILKLINRPIL VLRGLDGFVCHRRGSNQLDTNRSTYDVFHLSFRDGAYQIRGRGGGFWYTGSHGSVCSDGDLAEDFLFEFRERGRLAIRALSGKYLRGGASGLLRADADLPTGEALWEY
hide sequence
Ensembl Acc Id:
ENSRNOP00000051858 ⟸ ENSRNOT00000054975
RefSeq Acc Id:
XP_063125322 ⟸ XM_063269252
- Peptide Label:
isoform X2
RefSeq Acc Id:
XP_063125321 ⟸ XM_063269251
- Peptide Label:
isoform X1
- UniProtKB:
A6HLC3 (UniProtKB/TrEMBL), D3ZX02 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063125323 ⟸ XM_063269253
- Peptide Label:
isoform X3
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2014-02-13
Fscn2
fascin actin-bundling protein 2, retinal
Fscn2
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
Nomenclature updated to reflect human and mouse nomenclature
1299863
APPROVED
2008-04-30
Fscn2
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
Fscn2_predicted
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus) (predicted)
'predicted' is removed
2292626
APPROVED
2005-01-12
Fscn2_predicted
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus) (predicted)
Symbol and Name status set to approved
70820
APPROVED