Dhx30 (DExH-box helicase 30) - Rat Genome Database

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Gene: Dhx30 (DExH-box helicase 30) Rattus norvegicus
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Symbol: Dhx30
Name: DExH-box helicase 30
RGD ID: 1308888
Description: Predicted to enable RNA binding activity; chromatin binding activity; and helicase activity. Predicted to be involved in central nervous system development and mitochondrial large ribosomal subunit assembly. Predicted to be located in cytosol; mitochondrial nucleoid; and ribonucleoprotein granule. Predicted to be active in cytoplasm and nucleus. Orthologous to human DHX30 (DExH-box helicase 30); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ATP-dependent RNA helicase DHX30; DEAH (Asp-Glu-Ala-His) box helicase 30; DEAH (Asp-Glu-Ala-His) box polypeptide 30; DEAH box protein 30; DEAH-box helicase 30; LOC367172; MGC109411; putative ATP-dependent RNA helicase DHX30
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,943,186 - 118,975,319 (-)NCBIGRCr8
mRatBN7.28110,064,751 - 110,096,954 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,064,752 - 110,097,381 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8115,680,523 - 115,712,489 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,879,711 - 113,911,677 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,722,475 - 111,754,443 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08118,160,315 - 118,194,674 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8118,160,299 - 118,187,791 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08117,515,769 - 117,547,561 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48114,438,389 - 114,470,350 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18114,457,844 - 114,489,805 (-)NCBI
Celera8109,352,489 - 109,384,567 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Dhx30Ratautism spectrum disorder  ISODHX30 (Homo sapiens)8554872ClinVar Annotator: match by term: Autism and susceptiblity toClinVarPMID:25741868
Dhx30Ratautistic disorder  ISODHX30 (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:28327206 more ...
Dhx30RatDevelopmental Disabilities  ISODHX30 (Homo sapiens)8554872ClinVar Annotator: match by term: Global developmental delayClinVarPMID:25741868 more ...
Dhx30Ratepilepsy  ISODHX30 (Homo sapiens)8554872ClinVar Annotator: match by term: SeizureClinVarPMID:29100085
Dhx30Ratgenetic disease  ISODHX30 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 more ...
Dhx30RatNEURODEVELOPMENTAL DISORDER WITH SEVERE MOTOR IMPAIRMENT AND ABSENT LANGUAGE  ISODHX30 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
Dhx30RatProgressive Microcephaly with Seizures and Cerebral and Cerebellar Atrophy  ISODHX30 (Homo sapiens)8554872ClinVar Annotator: match by term: Microcephaly more ...ClinVarPMID:28492532
Object Symbol
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Original Reference(s)
Dhx30RatProstatic Neoplasms  ISODHX30 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:29610475
Object Symbol
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Original Reference(s)
Dhx30RatNEURODEVELOPMENTAL DISORDER WITH SEVERE MOTOR IMPAIRMENT AND ABSENT LANGUAGE  ISODHX30 (Homo sapiens)7240710 OMIM 

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Original Reference(s)
Dhx30Rat1,2-dimethylhydrazine multiple interactionsISODhx30 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DHX30 mRNACTDPMID:22206623
Dhx30Rat17alpha-ethynylestradiol increases expressionISODhx30 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of DHX30 mRNACTDPMID:17942748
Dhx30Rat17beta-estradiol multiple interactionsISODHX30 (Homo sapiens)6480464Estradiol inhibits the reaction [ESR1 protein binds to DHX30 protein]CTDPMID:29389661
Dhx30Rat17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactionsISODHX30 (Homo sapiens)6480464[Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to DHX30 protein modified form]CTDPMID:28751236
Dhx30Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISODhx30 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of DHX30 mRNACTDPMID:21570461
Dhx30Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of DHX30 mRNACTDPMID:33387578
Dhx30Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of DHX30 mRNACTDPMID:21346803
Dhx30Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of DHX30 mRNACTDPMID:21346803
Dhx30Rat2-methylcholine affects expressionISODHX30 (Homo sapiens)6480464beta-methylcholine affects the expression of DHX30 mRNACTDPMID:21179406
Dhx30Rat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of DHX30 proteinCTDPMID:34915118
Dhx30Rat4,4'-sulfonyldiphenol multiple interactionsISODHX30 (Homo sapiens)6480464bisphenol S inhibits the reaction [ESR1 protein binds to DHX30 protein]CTDPMID:29389661
Dhx30Ratacrolein multiple interactionsISODHX30 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of DHX30 mRNA more ...CTDPMID:32699268 and PMID:32845096
Dhx30Rataflatoxin B1 decreases methylationISODHX30 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of DHX30 intronCTDPMID:30157460
Dhx30Ratallethrin multiple interactionsEXP 6480464[cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of DHX30 proteinCTDPMID:34896426
Dhx30Ratalpha-pinene multiple interactionsISODHX30 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of DHX30 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of DHX30 mRNACTDPMID:32699268
Dhx30Ratbenzo[a]pyrene increases expressionISODhx30 (Mus musculus)6480464Benzo(a)pyrene results in increased expression of DHX30 mRNACTDPMID:22228805
Dhx30Ratbenzo[e]pyrene decreases methylationISODHX30 (Homo sapiens)6480464benzo(e)pyrene results in decreased methylation of DHX30 intronCTDPMID:30157460
Dhx30Ratbeta-lapachone increases expressionISODHX30 (Homo sapiens)6480464beta-lapachone results in increased expression of DHX30 mRNACTDPMID:38218311
Dhx30Ratbis(2-ethylhexyl) phthalate increases expressionISODhx30 (Mus musculus)6480464Diethylhexyl Phthalate results in increased expression of DHX30 mRNACTDPMID:33754040
Dhx30Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of DHX30 mRNACTDPMID:25181051 and PMID:34947998

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Biological Process

  
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Original Reference(s)
Dhx30Ratcentral nervous system development involved_inISSUniProtKB:Q99PU81600115GO_REF:0000024UniProtGO_REF:0000024
Dhx30Ratcentral nervous system development involved_inIEAUniProtKB:Q99PU8 and ensembl:ENSMUSP000001424891600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx30Ratcentral nervous system development involved_inISODhx30 (Mus musculus)1624291 PMID:25219788RGDPMID:25219788
Dhx30Ratmitochondrial large ribosomal subunit assembly involved_inISSUniProtKB:Q7L2E31600115GO_REF:0000024UniProtGO_REF:0000024
Dhx30Ratmitochondrial large ribosomal subunit assembly involved_inISODHX30 (Homo sapiens)1624291 PMID:25683715RGDPMID:25683715
Dhx30Ratmitochondrial large ribosomal subunit assembly involved_inIEAUniProtKB:Q7L2E3 and ensembl:ENSP000004056201600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx30Ratribosome biogenesis involved_inIEAUniProtKB-KW:KW-06901600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component
1 to 20 of 28 rows

  
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Original Reference(s)
Dhx30Ratcytoplasm located_inISODHX30 (Homo sapiens)1624291 PMID:29100085RGDPMID:29100085
Dhx30Ratcytoplasm located_inIEAUniProtKB:Q7L2E3 and ensembl:ENSP000004056201600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx30Ratcytoplasm located_inIEAUniProtKB:Q99PU8 and ensembl:ENSMUSP000001424891600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx30Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Dhx30Ratcytoplasm located_inISODhx30 (Mus musculus)1624291 PMID:25219788RGDPMID:25219788
Dhx30Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Dhx30Ratcytoplasm is_active_inIBAMGI:1919412 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Dhx30Ratcytoplasm located_inISSUniProtKB:Q7L2E31600115GO_REF:0000024UniProtGO_REF:0000024
Dhx30Ratcytoplasm located_inISSUniProtKB:Q99PU81600115GO_REF:0000024UniProtGO_REF:0000024
Dhx30Ratcytosol located_inISODHX30 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Dhx30Ratcytosol located_inIEAUniProtKB:Q7L2E3 and ensembl:ENSP000004056201600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx30Ratmitochondrial matrix located_inISODHX30 (Homo sapiens)1624291 PMID:23275553RGDPMID:23275553
Dhx30Ratmitochondrial matrix located_inIEAUniProtKB:Q7L2E3 and ensembl:ENSP000004056201600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx30Ratmitochondrial nucleoid located_inISSUniProtKB:Q7L2E31600115GO_REF:0000024UniProtGO_REF:0000024
Dhx30Ratmitochondrial nucleoid located_inIEAUniProtKB-KW:KW-11351600115GO_REF:0000043UniProtGO_REF:0000043
Dhx30Ratmitochondrial nucleoid located_inIEAUniProtKB:Q7L2E3 and ensembl:ENSP000004056201600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx30Ratmitochondrial nucleoid located_inIEAUniProtKB-SubCell:SL-02691600115GO_REF:0000044UniProtGO_REF:0000044
Dhx30Ratmitochondrial nucleoid located_inISODHX30 (Homo sapiens)1624291 PMID:18063578 and PMID:25683715RGDPMID:18063578 and PMID:25683715
Dhx30Ratmitochondrion located_inISODHX30 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Dhx30Ratmitochondrion located_inIEAUniProtKB-SubCell:SL-01731600115GO_REF:0000044UniProtGO_REF:0000044
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Molecular Function
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Original Reference(s)
Dhx30RatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
Dhx30RatATP binding enablesIEAInterPro:IPR0115451600115GO_REF:0000002InterProGO_REF:0000002
Dhx30RatATP hydrolysis activity enablesIEARHEA:130651600115GO_REF:0000116RHEAGO_REF:0000116
Dhx30Ratchromatin binding enablesISODHX30 (Homo sapiens)1624291 PMID:18063578RGDPMID:18063578
Dhx30Ratchromatin binding enablesIEAUniProtKB:Q7L2E3 and ensembl:ENSP000004056201600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx30Ratchromatin binding enablesISSUniProtKB:Q7L2E31600115GO_REF:0000024UniProtGO_REF:0000024
Dhx30RatDNA helicase activity enablesIBAFB:FBgn0032883 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Dhx30Ratdouble-stranded RNA binding enablesISODHX30 (Homo sapiens)1624291 PMID:21266579RGDPMID:21266579
Dhx30Ratdouble-stranded RNA binding enablesIEAUniProtKB:Q7L2E3 and ensembl:ENSP000004056201600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx30RatG-quadruplex RNA binding enablesIBAFB:FBgn0032883 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Dhx30Rathelicase activity enablesIEAUniProtKB-KW:KW-03471600115GO_REF:0000043UniProtGO_REF:0000043
Dhx30Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Dhx30Ratnucleic acid binding enablesIEAInterPro:IPR0115451600115GO_REF:0000002InterProGO_REF:0000002
Dhx30Ratnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
Dhx30Ratprotein binding enablesIPIUniProtKB:Q7Z2W48553585PMID:21204022UniProt 
Dhx30Ratprotein binding enablesIPIUniProtKB:Q8K3Y68553585PMID:21204022UniProt 
Dhx30Ratprotein binding enablesISODHX30 (Homo sapiens)1624291UniProtKB:P13569 more ...RGDPMID:17932509 more ...
Dhx30RatRNA binding enablesISSUniProtKB:Q7L2E31600115GO_REF:0000024UniProtGO_REF:0000024
Dhx30RatRNA binding enablesIEAUniProtKB:Q7L2E3 and ensembl:ENSP000004056201600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx30RatRNA binding enablesIEAUniProtKB-KW:KW-06941600115GO_REF:0000043UniProtGO_REF:0000043
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
5. DEXH-Box protein DHX30 is required for optimal function of the zinc-finger antiviral protein. Ye P, etal., Protein Cell. 2010 Oct;1(10):956-64. doi: 10.1007/s13238-010-0117-8. Epub 2010 Nov 9.
PMID:15489334   PMID:18063578   PMID:21266579   PMID:22658674   PMID:22681889   PMID:25219788   PMID:25683715   PMID:29100085   PMID:31904090  



Dhx30
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,943,186 - 118,975,319 (-)NCBIGRCr8
mRatBN7.28110,064,751 - 110,096,954 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,064,752 - 110,097,381 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8115,680,523 - 115,712,489 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,879,711 - 113,911,677 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,722,475 - 111,754,443 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08118,160,315 - 118,194,674 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8118,160,299 - 118,187,791 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08117,515,769 - 117,547,561 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48114,438,389 - 114,470,350 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18114,457,844 - 114,489,805 (-)NCBI
Celera8109,352,489 - 109,384,567 (-)NCBICelera
Cytogenetic Map8q32NCBI
DHX30
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38347,803,138 - 47,850,193 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl347,802,909 - 47,850,195 (+)EnsemblGRCh38hg38GRCh38
GRCh37347,844,628 - 47,891,683 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36347,819,655 - 47,866,687 (+)NCBINCBI36Build 36hg18NCBI36
Build 34347,819,654 - 47,866,686NCBI
Celera347,794,449 - 47,841,545 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef347,899,640 - 47,947,043 (+)NCBIHuRef
CHM1_1347,795,669 - 47,842,932 (+)NCBICHM1_1
T2T-CHM13v2.0347,830,461 - 47,877,524 (+)NCBIT2T-CHM13v2.0
Dhx30
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399109,913,387 - 109,946,728 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9109,913,388 - 109,946,898 (-)EnsemblGRCm39 Ensembl
GRCm389110,084,319 - 110,117,616 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9110,084,320 - 110,117,830 (-)EnsemblGRCm38mm10GRCm38
MGSCv379109,986,824 - 110,018,086 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369109,929,496 - 109,960,758 (-)NCBIMGSCv36mm8
Celera9109,812,519 - 109,843,847 (-)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.86NCBI
Dhx30
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542024,537,608 - 24,561,293 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542024,537,608 - 24,549,771 (-)NCBIChiLan1.0ChiLan1.0
DHX30
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2247,770,959 - 47,818,666 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1347,775,971 - 47,823,434 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0347,715,275 - 47,762,872 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1348,833,785 - 48,858,037 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl348,819,125 - 48,857,964 (+)Ensemblpanpan1.1panPan2
DHX30
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12041,102,064 - 41,131,464 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2041,102,080 - 41,129,429 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2041,019,046 - 41,048,443 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02041,585,579 - 41,614,984 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2041,585,582 - 41,614,892 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12040,827,709 - 40,857,125 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02041,229,130 - 41,258,515 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02041,508,803 - 41,538,213 (-)NCBIUU_Cfam_GSD_1.0
Dhx30
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118201,870,062 - 201,905,658 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365961,421,094 - 1,455,356 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365961,419,165 - 1,454,797 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DHX30
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1330,617,376 - 30,632,497 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11330,602,008 - 30,632,506 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21333,878,421 - 33,908,846 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DHX30
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1229,191,527 - 9,239,445 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl229,206,175 - 9,239,372 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041157,866,168 - 157,919,224 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dhx30
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473073,656,361 - 73,681,999 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473073,656,378 - 73,685,863 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Dhx30
52 total Variants

Predicted Target Of
Summary Value
Count of predictions:96
Count of miRNA genes:82
Interacting mature miRNAs:89
Transcripts:ENSRNOT00000048764
Prediction methods:Microtar, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 22 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat

1 to 10 of 22 rows
AU015424  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28110,064,769 - 110,065,001 (+)MAPPERmRatBN7.2
Rnor_6.08118,160,334 - 118,160,565NCBIRnor6.0
Rnor_5.08117,515,788 - 117,516,019UniSTSRnor5.0
RGSC_v3.48114,438,408 - 114,438,639UniSTSRGSC3.4
Celera8109,352,508 - 109,352,739UniSTS
Cytogenetic Map8q32UniSTS
BF393382  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28110,090,825 - 110,091,052 (+)MAPPERmRatBN7.2
Rnor_6.08118,186,406 - 118,186,632NCBIRnor6.0
Rnor_5.08117,541,558 - 117,541,784UniSTSRnor5.0
RGSC_v3.48114,464,347 - 114,464,573UniSTSRGSC3.4
Celera8109,378,562 - 109,378,788UniSTS
RH 3.4 Map81113.29UniSTS
Cytogenetic Map8q32UniSTS
Dhx30  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28110,067,074 - 110,068,396 (+)MAPPERmRatBN7.2
Rnor_6.08118,162,637 - 118,163,958NCBIRnor6.0
Rnor_5.08117,518,091 - 117,519,412UniSTSRnor5.0
RGSC_v3.48114,440,711 - 114,442,032UniSTSRGSC3.4
Celera8109,354,811 - 109,356,132UniSTS
Cytogenetic Map8q32UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000048764   ⟹   ENSRNOP00000043896
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8110,064,752 - 110,080,832 (-)Ensembl
Rnor_6.0 Ensembl8118,160,388 - 118,187,791 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000084838   ⟹   ENSRNOP00000069744
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8110,064,752 - 110,079,212 (-)Ensembl
Rnor_6.0 Ensembl8118,160,299 - 118,182,559 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094963   ⟹   ENSRNOP00000096872
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8110,064,752 - 110,078,846 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109037   ⟹   ENSRNOP00000089933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8110,064,752 - 110,097,381 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115057   ⟹   ENSRNOP00000077785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8110,064,752 - 110,096,839 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115080   ⟹   ENSRNOP00000095670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8110,064,757 - 110,096,540 (-)Ensembl
RefSeq Acc Id: NM_001013249   ⟹   NP_001013267
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,943,186 - 118,975,263 (-)NCBI
mRatBN7.28110,064,751 - 110,096,829 (-)NCBI
Rnor_6.08118,160,315 - 118,192,409 (-)NCBI
Rnor_5.08117,515,769 - 117,547,561 (-)NCBI
RGSC_v3.48114,438,389 - 114,470,350 (-)RGD
Celera8109,352,489 - 109,384,567 (-)RGD
Sequence:
RefSeq Acc Id: XM_006243826   ⟹   XP_006243888
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,943,186 - 118,965,107 (-)NCBI
mRatBN7.28110,064,751 - 110,082,034 (-)NCBI
Rnor_6.08118,160,315 - 118,177,589 (-)NCBI
Rnor_5.08117,515,769 - 117,547,561 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006243829   ⟹   XP_006243891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,943,186 - 118,965,109 (-)NCBI
mRatBN7.28110,064,751 - 110,082,034 (-)NCBI
Rnor_6.08118,160,315 - 118,177,589 (-)NCBI
Rnor_5.08117,515,769 - 117,547,561 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006243831   ⟹   XP_006243893
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,943,186 - 118,975,319 (-)NCBI
mRatBN7.28110,064,751 - 110,096,954 (-)NCBI
Rnor_6.08118,160,315 - 118,192,457 (-)NCBI
Rnor_5.08117,515,769 - 117,547,561 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017595799   ⟹   XP_017451288
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,943,186 - 118,975,128 (-)NCBI
mRatBN7.28110,064,751 - 110,096,715 (-)NCBI
Rnor_6.08118,160,315 - 118,192,330 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017595800   ⟹   XP_017451289
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,943,186 - 118,974,657 (-)NCBI
mRatBN7.28110,064,751 - 110,096,219 (-)NCBI
Rnor_6.08118,160,315 - 118,192,330 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063265938   ⟹   XP_063122008
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,943,186 - 118,970,672 (-)NCBI
1 to 5 of 13 rows
1 to 5 of 13 rows
RefSeq Acc Id: NP_001013267   ⟸   NM_001013249
- UniProtKB: Q5BJS0 (UniProtKB/Swiss-Prot),   A0A8I5YC14 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243893   ⟸   XM_006243831
- Peptide Label: isoform X5
- UniProtKB: A0A8I6ARW5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243891   ⟸   XM_006243829
- Peptide Label: isoform X4
- UniProtKB: A0A8I5YC14 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243888   ⟸   XM_006243826
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QL99 (UniProtKB/TrEMBL),   A6I3D1 (UniProtKB/TrEMBL),   A0A8I5YC14 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451288   ⟸   XM_017595799
- Peptide Label: isoform X2
- UniProtKB: Q5BJS0 (UniProtKB/Swiss-Prot),   A0A8I5YC14 (UniProtKB/TrEMBL)
- Sequence:
Name Modeler Protein Id AA Range Protein Structure
AF-Q5BJS0-F1-model_v2 AlphaFold Q5BJS0 1-1194 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 40 of 43 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-29082 BioCyc
Ensembl Genes ENSRNOG00000029194 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000048764 ENTREZGENE
  ENSRNOT00000084838 ENTREZGENE
  ENSRNOT00000109037 ENTREZGENE
Gene3D-CATH 1.20.120.1080 UniProtKB/Swiss-Prot
  3.30.160.20 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7318733 IMAGE-MGC_LOAD
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/Swiss-Prot
  DNA/RNA_helicase_DEAH_CS UniProtKB/Swiss-Prot
  DUF1605 UniProtKB/Swiss-Prot
  Helicase-assoc_dom UniProtKB/Swiss-Prot
  Helicase_ATP-bd UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
KEGG Report rno:367172 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109411 IMAGE-MGC_LOAD
NCBI Gene 367172 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE UniProtKB/Swiss-Prot
  ATP-DEPENDENT RNA HELICASE DHX30 UniProtKB/Swiss-Prot
Pfam DEAD UniProtKB/Swiss-Prot
  HA2_C UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  OB_NTP_bind UniProtKB/Swiss-Prot
PhenoGen Dhx30 PhenoGen
PROSITE DEAH_ATP_HELICASE UniProtKB/Swiss-Prot
  HELICASE_ATP_BIND_1 UniProtKB/Swiss-Prot
  HELICASE_CTER UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000029194 RatGTEx
SMART DEXDc UniProtKB/Swiss-Prot
  HA2 UniProtKB/Swiss-Prot
  HELICc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A0G2JW51_RAT UniProtKB/TrEMBL
  A0A8I5YC14 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ARW5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AU43_RAT UniProtKB/TrEMBL
  A0A8I6GHS9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QL99 ENTREZGENE, UniProtKB/TrEMBL
1 to 40 of 43 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-10-05 Dhx30  DExH-box helicase 30  Dhx30  DEAH-box helicase 30  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-01-13 Dhx30  DEAH-box helicase 30  Dhx30  DEAH (Asp-Glu-Ala-His) box helicase 30  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-01 Dhx30  DEAH (Asp-Glu-Ala-His) box helicase 30  Dhx30  DEAH (Asp-Glu-Ala-His) box polypeptide 30  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Dhx30  DEAH (Asp-Glu-Ala-His) box polypeptide 30  Dhx30_predicted  DEAH (Asp-Glu-Ala-His) box polypeptide 30 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Dhx30_predicted  DEAH (Asp-Glu-Ala-His) box polypeptide 30 (predicted)      Symbol and Name status set to approved 70820 APPROVED