Dhx30 (DExH-box helicase 30) - Rat Genome Database

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Gene: Dhx30 (DExH-box helicase 30) Rattus norvegicus
Analyze
Symbol: Dhx30
Name: DExH-box helicase 30
RGD ID: 1308888
Description: Predicted to enable RNA binding activity; chromatin binding activity; and helicase activity. Predicted to be involved in central nervous system development and mitochondrial large ribosomal subunit assembly. Predicted to be located in mitochondrial nucleoid and ribonucleoprotein granule. Predicted to be active in cytoplasm and nucleus. Orthologous to human DHX30 (DExH-box helicase 30); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ATP-dependent RNA helicase DHX30; DEAH (Asp-Glu-Ala-His) box helicase 30; DEAH (Asp-Glu-Ala-His) box polypeptide 30; DEAH box protein 30; DEAH-box helicase 30; LOC367172; MGC109411; putative ATP-dependent RNA helicase DHX30
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,943,186 - 118,975,319 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8118,943,187 - 118,975,592 (-)EnsemblGRCr8
mRatBN7.28110,064,751 - 110,096,954 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,064,752 - 110,097,381 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8115,680,523 - 115,712,489 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,879,711 - 113,911,677 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,722,475 - 111,754,443 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08118,160,315 - 118,194,674 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8118,160,299 - 118,187,791 (-)Ensemblrn6Rnor6.0
Rnor_5.08117,515,769 - 117,547,561 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48114,438,389 - 114,470,350 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8109,352,489 - 109,384,567 (-)NCBICelera
RGSC_v3.18114,457,844 - 114,489,805 (-)NCBI
Cytogenetic Map8q32NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
allethrin  (EXP)
alpha-pinene  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
caffeine  (ISO)
clofibrate  (ISO)
clozapine  (ISO)
cocaine  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
cyhalothrin  (EXP)
cypermethrin  (EXP)
cyproterone acetate  (ISO)
dimethyl sulfoxide  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
fenthion  (ISO)
fenvalerate  (EXP)
flutamide  (EXP)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
inulin  (ISO)
ivermectin  (ISO)
methapyrilene  (ISO)
methidathion  (ISO)
Monobutylphthalate  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
pyrethrins  (EXP)
SB 431542  (ISO)
selenium atom  (ISO)
sevoflurane  (EXP)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA,ISO,ISS)
cytosol  (IEA,ISO)
mitochondrial matrix  (IEA,ISO)
mitochondrial nucleoid  (IEA,ISO,ISS)
mitochondrion  (IEA,ISO,ISS)
nucleus  (IBA)
ribonucleoprotein granule  (IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
5. DEXH-Box protein DHX30 is required for optimal function of the zinc-finger antiviral protein. Ye P, etal., Protein Cell. 2010 Oct;1(10):956-64. doi: 10.1007/s13238-010-0117-8. Epub 2010 Nov 9.
Additional References at PubMed
PMID:15489334   PMID:18063578   PMID:21266579   PMID:22658674   PMID:22681889   PMID:25219788   PMID:25683715   PMID:29100085   PMID:31904090  


Genomics

Comparative Map Data
Dhx30
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,943,186 - 118,975,319 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8118,943,187 - 118,975,592 (-)EnsemblGRCr8
mRatBN7.28110,064,751 - 110,096,954 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,064,752 - 110,097,381 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8115,680,523 - 115,712,489 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,879,711 - 113,911,677 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,722,475 - 111,754,443 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08118,160,315 - 118,194,674 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8118,160,299 - 118,187,791 (-)Ensemblrn6Rnor6.0
Rnor_5.08117,515,769 - 117,547,561 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48114,438,389 - 114,470,350 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8109,352,489 - 109,384,567 (-)NCBICelera
RGSC_v3.18114,457,844 - 114,489,805 (-)NCBI
Cytogenetic Map8q32NCBI
DHX30
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38347,803,138 - 47,850,193 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl347,802,641 - 47,851,617 (+)Ensemblhg38GRCh38
GRCh37347,844,628 - 47,891,683 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36347,819,655 - 47,866,687 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34347,819,654 - 47,866,686NCBI
Celera347,794,449 - 47,841,545 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef347,899,640 - 47,947,043 (+)NCBIHuRef
CHM1_1347,795,669 - 47,842,932 (+)NCBICHM1_1
T2T-CHM13v2.0347,830,461 - 47,877,524 (+)NCBIT2T-CHM13v2.0
Dhx30
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399109,913,387 - 109,946,728 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9109,913,388 - 109,946,898 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm389110,084,319 - 110,117,616 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9110,084,320 - 110,117,830 (-)Ensemblmm10GRCm38
MGSCv379109,986,824 - 110,018,086 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv369109,929,496 - 109,960,758 (-)NCBIMGSCv36mm8
Celera9109,812,519 - 109,843,847 (-)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.86NCBI
Dhx30
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542024,537,608 - 24,561,293 (-)Ensembl
ChiLan1.0NW_00495542024,537,608 - 24,549,771 (-)NCBIChiLan1.0ChiLan1.0
DHX30
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2247,770,959 - 47,818,666 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1347,775,971 - 47,823,434 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0347,715,275 - 47,762,872 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1348,833,785 - 48,858,037 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl348,819,125 - 48,857,964 (+)EnsemblpanPan2panpan1.1
DHX30
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12041,102,064 - 41,131,464 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2041,102,080 - 41,129,429 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2041,019,046 - 41,048,443 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02041,585,579 - 41,614,984 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2041,585,582 - 41,614,892 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12040,827,709 - 40,857,125 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02041,229,130 - 41,258,515 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02041,508,803 - 41,538,213 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dhx30
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118201,870,062 - 201,905,658 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365961,421,094 - 1,455,356 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365961,419,165 - 1,454,797 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DHX30
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1330,617,376 - 30,632,497 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11330,602,008 - 30,632,506 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21333,878,421 - 33,908,846 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DHX30
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1229,191,527 - 9,239,445 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl229,206,175 - 9,239,372 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041157,866,168 - 157,919,224 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dhx30
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473073,656,361 - 73,681,999 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473073,656,378 - 73,685,863 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Dhx30
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v18100,685,556 - 100,718,517 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dhx30
103 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:96
Count of miRNA genes:82
Interacting mature miRNAs:89
Transcripts:ENSRNOT00000048764
Prediction methods:Microtar, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)882352698127352698Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)880768445125768445Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)880768445125768445Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8103375781129871912Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)898145073122898010Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)880768445125768445Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)880768445125768445Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
AU015424  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28110,064,769 - 110,065,001 (+)MAPPERmRatBN7.2
Rnor_6.08118,160,334 - 118,160,565NCBIRnor6.0
Rnor_5.08117,515,788 - 117,516,019UniSTSRnor5.0
RGSC_v3.48114,438,408 - 114,438,639UniSTSRGSC3.4
Celera8109,352,508 - 109,352,739UniSTS
Cytogenetic Map8q32UniSTS
BF393382  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28110,090,825 - 110,091,052 (+)MAPPERmRatBN7.2
Rnor_6.08118,186,406 - 118,186,632NCBIRnor6.0
Rnor_5.08117,541,558 - 117,541,784UniSTSRnor5.0
RGSC_v3.48114,464,347 - 114,464,573UniSTSRGSC3.4
Celera8109,378,562 - 109,378,788UniSTS
RH 3.4 Map81113.29UniSTS
Cytogenetic Map8q32UniSTS
Dhx30  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28110,067,074 - 110,068,396 (+)MAPPERmRatBN7.2
Rnor_6.08118,162,637 - 118,163,958NCBIRnor6.0
Rnor_5.08117,518,091 - 117,519,412UniSTSRnor5.0
RGSC_v3.48114,440,711 - 114,442,032UniSTSRGSC3.4
Celera8109,354,811 - 109,356,132UniSTS
Cytogenetic Map8q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000048764   ⟹   ENSRNOP00000043896
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8118,943,187 - 118,959,451 (-)Ensembl
mRatBN7.2 Ensembl8110,064,752 - 110,080,832 (-)Ensembl
Rnor_6.0 Ensembl8118,160,388 - 118,187,791 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000084838   ⟹   ENSRNOP00000069744
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8118,943,187 - 118,975,240 (-)Ensembl
mRatBN7.2 Ensembl8110,064,752 - 110,079,212 (-)Ensembl
Rnor_6.0 Ensembl8118,160,299 - 118,182,559 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094963   ⟹   ENSRNOP00000096872
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8118,943,187 - 118,957,280 (-)Ensembl
mRatBN7.2 Ensembl8110,064,752 - 110,078,846 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109037   ⟹   ENSRNOP00000089933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8118,943,187 - 118,975,592 (-)Ensembl
mRatBN7.2 Ensembl8110,064,752 - 110,097,381 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115057   ⟹   ENSRNOP00000077785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8118,943,187 - 118,975,592 (-)Ensembl
mRatBN7.2 Ensembl8110,064,752 - 110,096,839 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115080   ⟹   ENSRNOP00000095670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8118,943,187 - 118,974,723 (-)Ensembl
mRatBN7.2 Ensembl8110,064,757 - 110,096,540 (-)Ensembl
RefSeq Acc Id: NM_001013249   ⟹   NP_001013267
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,943,186 - 118,975,263 (-)NCBI
mRatBN7.28110,064,751 - 110,096,829 (-)NCBI
Rnor_6.08118,160,315 - 118,192,409 (-)NCBI
Rnor_5.08117,515,769 - 117,547,561 (-)NCBI
RGSC_v3.48114,438,389 - 114,470,350 (-)RGD
Celera8109,352,489 - 109,384,567 (-)RGD
Sequence:
RefSeq Acc Id: XM_006243826   ⟹   XP_006243888
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,943,186 - 118,965,107 (-)NCBI
mRatBN7.28110,064,751 - 110,082,034 (-)NCBI
Rnor_6.08118,160,315 - 118,177,589 (-)NCBI
Rnor_5.08117,515,769 - 117,547,561 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006243829   ⟹   XP_006243891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,943,186 - 118,965,109 (-)NCBI
mRatBN7.28110,064,751 - 110,082,034 (-)NCBI
Rnor_6.08118,160,315 - 118,177,589 (-)NCBI
Rnor_5.08117,515,769 - 117,547,561 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006243831   ⟹   XP_006243893
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,943,186 - 118,975,319 (-)NCBI
mRatBN7.28110,064,751 - 110,096,954 (-)NCBI
Rnor_6.08118,160,315 - 118,192,457 (-)NCBI
Rnor_5.08117,515,769 - 117,547,561 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017595799   ⟹   XP_017451288
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,943,186 - 118,975,128 (-)NCBI
mRatBN7.28110,064,751 - 110,096,715 (-)NCBI
Rnor_6.08118,160,315 - 118,192,330 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017595800   ⟹   XP_017451289
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,943,186 - 118,974,657 (-)NCBI
mRatBN7.28110,064,751 - 110,096,219 (-)NCBI
Rnor_6.08118,160,315 - 118,192,330 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063265938   ⟹   XP_063122008
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,943,186 - 118,970,672 (-)NCBI
RefSeq Acc Id: NP_001013267   ⟸   NM_001013249
- UniProtKB: Q5BJS0 (UniProtKB/Swiss-Prot),   A0A8I5YC14 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243893   ⟸   XM_006243831
- Peptide Label: isoform X5
- UniProtKB: A0A8I6ARW5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243891   ⟸   XM_006243829
- Peptide Label: isoform X4
- UniProtKB: A0A8I5YC14 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243888   ⟸   XM_006243826
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QL99 (UniProtKB/TrEMBL),   A6I3D1 (UniProtKB/TrEMBL),   A0A8I5YC14 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451288   ⟸   XM_017595799
- Peptide Label: isoform X2
- UniProtKB: Q5BJS0 (UniProtKB/Swiss-Prot),   A0A8I5YC14 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451289   ⟸   XM_017595800
- Peptide Label: isoform X2
- UniProtKB: Q5BJS0 (UniProtKB/Swiss-Prot),   A0A8I5YC14 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069744   ⟸   ENSRNOT00000084838
Ensembl Acc Id: ENSRNOP00000043896   ⟸   ENSRNOT00000048764
Ensembl Acc Id: ENSRNOP00000089933   ⟸   ENSRNOT00000109037
Ensembl Acc Id: ENSRNOP00000095670   ⟸   ENSRNOT00000115080
Ensembl Acc Id: ENSRNOP00000096872   ⟸   ENSRNOT00000094963
Ensembl Acc Id: ENSRNOP00000077785   ⟸   ENSRNOT00000115057
RefSeq Acc Id: XP_063122008   ⟸   XM_063265938
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GHS9 (UniProtKB/TrEMBL),   A0A8I5YC14 (UniProtKB/TrEMBL)
Protein Domains
DRBM   dsRNA binding   Helicase ATP-binding   Helicase C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5BJS0-F1-model_v2 AlphaFold Q5BJS0 1-1194 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308888 AgrOrtholog
BioCyc Gene G2FUF-29082 BioCyc
Ensembl Genes ENSRNOG00000029194 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000048764 ENTREZGENE
  ENSRNOT00000084838 ENTREZGENE
  ENSRNOT00000109037 ENTREZGENE
Gene3D-CATH 1.20.120.1080 UniProtKB/Swiss-Prot
  3.30.160.20 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7318733 IMAGE-MGC_LOAD
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/Swiss-Prot
  DNA/RNA_helicase_DEAH_CS UniProtKB/Swiss-Prot
  DSRM_2 UniProtKB/Swiss-Prot
  DUF1605 UniProtKB/Swiss-Prot
  Helicase-assoc_dom UniProtKB/Swiss-Prot
  Helicase_ATP-bd UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
KEGG Report rno:367172 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109411 IMAGE-MGC_LOAD
NCBI Gene 367172 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE UniProtKB/Swiss-Prot
  ATP-DEPENDENT RNA HELICASE DHX30 UniProtKB/Swiss-Prot
Pfam DEAD UniProtKB/Swiss-Prot
  DSRM_2 UniProtKB/Swiss-Prot
  HA2_C UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  OB_NTP_bind UniProtKB/Swiss-Prot
PhenoGen Dhx30 PhenoGen
PROSITE DEAH_ATP_HELICASE UniProtKB/Swiss-Prot
  HELICASE_ATP_BIND_1 UniProtKB/Swiss-Prot
  HELICASE_CTER UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000029194 RatGTEx
SMART DEXDc UniProtKB/Swiss-Prot
  HA2 UniProtKB/Swiss-Prot
  HELICc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A0G2JW51_RAT UniProtKB/TrEMBL
  A0A8I5YC14 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ARW5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AU43_RAT UniProtKB/TrEMBL
  A0A8I6GHS9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QL99 ENTREZGENE, UniProtKB/TrEMBL
  A6I3D1 ENTREZGENE, UniProtKB/TrEMBL
  A6I3D2_RAT UniProtKB/TrEMBL
  DHX30_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-10-05 Dhx30  DExH-box helicase 30  Dhx30  DEAH-box helicase 30  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-01-13 Dhx30  DEAH-box helicase 30  Dhx30  DEAH (Asp-Glu-Ala-His) box helicase 30  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-01 Dhx30  DEAH (Asp-Glu-Ala-His) box helicase 30  Dhx30  DEAH (Asp-Glu-Ala-His) box polypeptide 30  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Dhx30  DEAH (Asp-Glu-Ala-His) box polypeptide 30  Dhx30_predicted  DEAH (Asp-Glu-Ala-His) box polypeptide 30 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Dhx30_predicted  DEAH (Asp-Glu-Ala-His) box polypeptide 30 (predicted)      Symbol and Name status set to approved 70820 APPROVED