Ripply2 (ripply transcriptional repressor 2) - Rat Genome Database

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Gene: Ripply2 (ripply transcriptional repressor 2) Rattus norvegicus
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Symbol: Ripply2
Name: ripply transcriptional repressor 2
RGD ID: 1308746
Description: Predicted to be involved in embryonic pattern specification and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including Notch signaling pathway; post-anal tail morphogenesis; and regionalization. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in spondylocostal dysostosis 6. Orthologous to human RIPPLY2 (ripply transcriptional repressor 2); INTERACTS WITH bisphenol A; methamphetamine; SCH 23390.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC363111; RGD1308746; ripply2 homolog; ripply2 homolog (zebrafish); similar to Down syndrome critical region protein 6
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8896,854,393 - 96,858,963 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl896,854,508 - 96,858,963 (+)EnsemblGRCr8
mRatBN7.2887,974,444 - 87,979,002 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl887,974,776 - 87,978,969 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx893,644,365 - 93,648,821 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0891,843,583 - 91,848,039 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0889,680,879 - 89,685,334 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0894,676,579 - 94,691,125 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl894,686,938 - 94,691,041 (+)Ensemblrn6Rnor6.0
Rnor_5.0894,184,957 - 94,199,385 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4892,272,079 - 92,276,182 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera887,550,383 - 87,564,833 (+)NCBICelera
RGSC_v3.1892,291,533 - 92,295,746 (+)NCBI
Cytogenetic Map8q31NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16326386   PMID:17531978   PMID:20346937  


Genomics

Comparative Map Data
Ripply2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8896,854,393 - 96,858,963 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl896,854,508 - 96,858,963 (+)EnsemblGRCr8
mRatBN7.2887,974,444 - 87,979,002 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl887,974,776 - 87,978,969 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx893,644,365 - 93,648,821 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0891,843,583 - 91,848,039 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0889,680,879 - 89,685,334 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0894,676,579 - 94,691,125 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl894,686,938 - 94,691,041 (+)Ensemblrn6Rnor6.0
Rnor_5.0894,184,957 - 94,199,385 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4892,272,079 - 92,276,182 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera887,550,383 - 87,564,833 (+)NCBICelera
RGSC_v3.1892,291,533 - 92,295,746 (+)NCBI
Cytogenetic Map8q31NCBI
RIPPLY2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38683,853,229 - 83,857,515 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl683,853,360 - 83,857,515 (+)Ensemblhg38GRCh38
GRCh37684,562,948 - 84,567,234 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36684,619,704 - 84,623,953 (+)NCBIBuild 36Build 36hg18NCBI36
Celera684,996,340 - 85,000,589 (+)NCBICelera
Cytogenetic Map6q14.2NCBI
HuRef681,792,540 - 81,796,789 (+)NCBIHuRef
CHM1_1684,660,599 - 84,664,848 (+)NCBICHM1_1
T2T-CHM13v2.0685,076,512 - 85,080,798 (+)NCBIT2T-CHM13v2.0
Ripply2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39986,897,590 - 86,902,494 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl986,897,590 - 86,901,970 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38987,015,537 - 87,020,441 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl987,015,537 - 87,019,917 (+)Ensemblmm10GRCm38
MGSCv37986,910,372 - 86,914,751 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36986,813,266 - 86,817,862 (+)NCBIMGSCv36mm8
Celera984,106,720 - 84,111,102 (+)NCBICelera
Cytogenetic Map9E3.1NCBI
cM Map946.69NCBI
Ripply2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541111,418,744 - 11,422,766 (+)NCBIChiLan1.0ChiLan1.0
RIPPLY2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25103,952,209 - 103,958,674 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16101,849,018 - 101,855,520 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0681,748,370 - 81,754,129 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1685,022,737 - 85,027,930 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl685,022,737 - 85,027,930 (+)EnsemblpanPan2panpan1.1
RIPPLY2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11244,144,821 - 44,168,236 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Ripply2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494679,365,571 - 79,369,757 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365107,101,148 - 7,105,185 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365107,101,148 - 7,106,184 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RIPPLY2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl182,428,047 - 82,432,638 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1182,427,956 - 82,432,844 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2192,676,722 - 92,681,602 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RIPPLY2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1138,516,589 - 8,522,224 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl138,518,101 - 8,522,091 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040184,730,364 - 184,736,686 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ripply2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462479910,750,928 - 10,755,797 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ripply2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1881,049,099 - 81,053,602 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ripply2
22 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:122
Count of miRNA genes:102
Interacting mature miRNAs:109
Transcripts:ENSRNOT00000013285
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)862848139107848139Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)863141536109261840Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)882352698127352698Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)858337123103337123Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)862848139107848139Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)880768445125768445Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)862970527107970527Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)839106363103375781Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)862848139107848139Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)862848139107848139Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)862848139107848139Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)862848139107848139Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)85158969999045312Rat
71120Niddm21Non-insulin dependent diabetes mellitus QTL 213.73blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)866992095111992095Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)860248093105248093Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)839106363103375781Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)839106258103375958Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)862848139107848139Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)863404444108404444Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)855428416107963099Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)862963099107963099Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)880768445125768445Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)850763951107970527Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
724540Uae8Urinary albumin excretion QTL 85urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)839106258103375958Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)862982864107982864Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)880768445125768445Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)880768445125768445Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
3 48 114 22 11 9 28 9 102 85 1 105 5 40 2 12 12

Sequence


Ensembl Acc Id: ENSRNOT00000013285   ⟹   ENSRNOP00000013285
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl896,854,538 - 96,858,963 (+)Ensembl
mRatBN7.2 Ensembl887,974,776 - 87,978,969 (+)Ensembl
Rnor_6.0 Ensembl894,686,938 - 94,691,041 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000144740   ⟹   ENSRNOP00000098761
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl896,854,508 - 96,858,963 (+)Ensembl
RefSeq Acc Id: NM_001398742   ⟹   NP_001385671
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8896,854,508 - 96,858,963 (+)NCBI
mRatBN7.2887,974,547 - 87,979,002 (+)NCBI
RefSeq Acc Id: XM_063265791   ⟹   XP_063121861
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8896,854,393 - 96,858,827 (+)NCBI
RefSeq Acc Id: XM_343444   ⟹   XP_343445
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8896,854,393 - 96,858,955 (+)NCBI
mRatBN7.2887,974,444 - 87,978,995 (+)NCBI
Rnor_6.0894,686,764 - 94,691,125 (+)NCBI
Rnor_5.0894,184,957 - 94,199,385 (+)NCBI
RGSC_v3.4892,272,079 - 92,276,182 (+)RGD
Sequence:
RefSeq Acc Id: XP_343445   ⟸   XM_343444
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000013285   ⟸   ENSRNOT00000013285
RefSeq Acc Id: NP_001385671   ⟸   NM_001398742
RefSeq Acc Id: XP_063121861   ⟸   XM_063265791
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000098761   ⟸   ENSRNOT00000144740

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZRE0-F1-model_v2 AlphaFold D3ZRE0 1-128 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696170
Promoter ID:EPDNEW_R6688
Type:single initiation site
Name:Ripply2_1
Description:ripply transcriptional repressor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0894,686,951 - 94,687,011EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308746 AgrOrtholog
BioCyc Gene G2FUF-29634 BioCyc
Ensembl Genes ENSRNOG00000010004 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013285 ENTREZGENE
  ENSRNOT00000013285.7 UniProtKB/TrEMBL
  ENSRNOT00000144740 ENTREZGENE
  ENSRNOT00000144740.1 UniProtKB/TrEMBL
InterPro Ripply_fam UniProtKB/TrEMBL
NCBI Gene 363111 ENTREZGENE
PANTHER PROTEIN RIPPLY2 UniProtKB/TrEMBL
  PTHR16770 UniProtKB/TrEMBL
Pfam Ripply UniProtKB/TrEMBL
PhenoGen Ripply2 PhenoGen
RatGTEx ENSRNOG00000010004 RatGTEx
UniProt A0ABK0LF64_RAT UniProtKB/TrEMBL
  D3ZRE0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-07 Ripply2  ripply transcriptional repressor 2  Ripply2  ripply2 homolog (zebrafish)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-26 Ripply2  ripply2 homolog (zebrafish)  RGD1308746_predicted  similar to Down syndrome critical region protein 6 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1308746_predicted  similar to Down syndrome critical region protein 6 (predicted)  LOC363111_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC363111_predicted  similar to Down syndrome critical region protein 6 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL