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Gene: Ptp4a3 (protein tyrosine phosphatase 4A3) Rattus norvegicus

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Symbol:

Ptp4a3

Name:

protein tyrosine phosphatase 4A3

RGD ID:

1308687

Description:

Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in several processes, including endothelial cell migration; positive regulation of establishment of protein localization; and positive regulation of non-canonical NF-kappaB signal transduction. Predicted to act upstream of or within several processes, including cellular response to leukemia inhibitory factor; positive regulation of vascular permeability; and regulation of vascular endothelial growth factor signaling pathway. Predicted to be located in early endosome and plasma membrane. Predicted to be active in cytoplasm and nucleus. Orthologous to human PTP4A3 (protein tyrosine phosphatase 4A3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; acrylamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC362930; protein tyrosine phosphatase type IVA 3; protein tyrosine phosphatase type IVA, member 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PTP4A3 (protein tyrosine phosphatase 4A3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Ptp4a3 (protein tyrosine phosphatase 4a3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ptp4a3 (protein tyrosine phosphatase 4A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PTP4A3 (protein tyrosine phosphatase 4A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PTP4A3 (protein tyrosine phosphatase 4A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ptp4a3 (protein tyrosine phosphatase 4A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PTP4A3 (protein tyrosine phosphatase 4A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PTP4A3 (protein tyrosine phosphatase 4A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ptp4a3 (protein tyrosine phosphatase 4A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ptp4a3 (protein tyrosine phosphatase 4A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	PTP4A3 (protein tyrosine phosphatase 4A3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ptp4a3 (protein tyrosine phosphatase 4a3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ptp4a3a (protein tyrosine phosphatase type IVA, member 3a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	T19D2.2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	PRL-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ptp4a3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	ptp4a3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	107,518,220 - 107,549,949 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	107,541,047 - 107,549,949 (+)	Ensembl				GRCr8
mRatBN7.2	7	105,650,640 - 105,660,921 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	105,628,029 - 105,660,919 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	107,413,296 - 107,419,095 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	109,634,779 - 109,640,578 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	109,582,889 - 109,588,687 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	114,969,699 - 115,002,902 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	114,997,103 - 115,002,902 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	114,892,674 - 114,924,154 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	111,462,191 - 111,468,045 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	102,062,262 - 102,068,065 (+)	NCBI		Celera
RGSC_v3.1	7	111,467,866 - 111,502,275 (+)	NCBI
Cytogenetic Map	7	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Colonic Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-acetamidofluorene (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

4-hydroxyphenyl retinamide (ISO)

acrylamide (EXP,ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

amitrole (EXP)

amphetamine (EXP)

Azoxymethane (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP)

bisphenol F (EXP)

bortezomib (ISO)

Butylbenzyl phthalate (ISO)

C60 fullerene (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

camptothecin (ISO)

cantharidin (ISO)

choline (ISO)

cisplatin (ISO)

cycloheximide (ISO)

disodium selenite (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (ISO)

ethanol (ISO)

fenvalerate (EXP)

folic acid (ISO)

hypochlorous acid (ISO)

indole-3-methanol (EXP)

inulin (ISO)

L-methionine (ISO)

lead diacetate (ISO)

lead(0) (ISO)

lipopolysaccharide (ISO)

mercury dibromide (ISO)

methyl methanesulfonate (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

okadaic acid (ISO)

ozone (EXP,ISO)

paracetamol (EXP)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

potassium dichromate (ISO)

quercetin (ISO)

raloxifene (ISO)

rotenone (EXP)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (EXP,ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tamoxifen (ISO)

thimerosal (ISO)

triphenyl phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to leukemia inhibitory factor (ISO)

endothelial cell migration (IBA,IEA,ISO)

Notch signaling pathway (ISO)

positive regulation of vascular permeability (ISO)

regulation of signal transduction (IEA)

regulation of vascular endothelial growth factor signaling pathway (ISO)

Cellular Component

cytoplasm (IBA,IEA,ISO)

early endosome (IEA)

nucleus (IBA,IEA,ISO)

plasma membrane (IEA)

Molecular Function

hydrolase activity (IEA)

phosphoprotein phosphatase activity (IEA)

protein binding (ISO)

protein tyrosine phosphatase activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:17018620	PMID:20439489	PMID:23117660	PMID:23178297	PMID:24403062

Genomics

Comparative Map Data

Ptp4a3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	107,518,220 - 107,549,949 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	107,541,047 - 107,549,949 (+)	Ensembl				GRCr8
mRatBN7.2	7	105,650,640 - 105,660,921 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	105,628,029 - 105,660,919 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	107,413,296 - 107,419,095 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	109,634,779 - 109,640,578 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	109,582,889 - 109,588,687 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	114,969,699 - 115,002,902 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	114,997,103 - 115,002,902 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	114,892,674 - 114,924,154 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	111,462,191 - 111,468,045 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	102,062,262 - 102,068,065 (+)	NCBI		Celera
RGSC_v3.1	7	111,467,866 - 111,502,275 (+)	NCBI
Cytogenetic Map	7	q34	NCBI

PTP4A3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	141,392,021 - 141,432,454 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	141,391,497 - 141,432,456 (+)	Ensembl			hg38	GRCh38
GRCh37	8	142,402,121 - 142,442,554 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	142,501,189 - 142,510,802 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	8	142,501,188 - 142,510,802	NCBI
Celera	8	138,607,734 - 138,608,044 (+)	NCBI		Celera
Cytogenetic Map	8	q24.3	NCBI
HuRef	8	137,748,484 - 137,759,930 (+)	NCBI		HuRef
CHM1_1	8	142,471,719 - 142,482,782 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	142,513,520 - 142,559,812 (+)	NCBI		T2T-CHM13v2.0

Ptp4a3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	73,594,991 - 73,629,075 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	73,594,994 - 73,630,615 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	73,723,145 - 73,758,766 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	73,723,145 - 73,758,766 (+)	Ensembl			mm10	GRCm38
MGSCv37	15	73,553,575 - 73,589,196 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	73,575,667 - 73,586,021 (+)	NCBI		MGSCv36	mm8
Celera	15	75,228,105 - 75,263,862 (+)	NCBI		Celera
Cytogenetic Map	15	D3	NCBI
cM Map	15	34.05	NCBI

Ptp4a3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955454	429,792 - 441,268 (+)	Ensembl
ChiLan1.0	NW_004955454	429,051 - 440,328 (+)	NCBI	ChiLan1.0	ChiLan1.0

PTP4A3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	158,783,895 - 158,830,201 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	134,314,474 - 134,360,646 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	138,062,418 - 138,108,281 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	141,166,898 - 141,187,383 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	141,166,898 - 141,188,314 (+)	Ensembl			panPan2	panpan1.1

PTP4A3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	35,875,467 - 35,886,330 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	35,880,005 - 35,886,324 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	35,734,643 - 35,745,436 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	36,261,162 - 36,271,948 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	36,262,778 - 36,273,628 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	35,981,264 - 35,992,052 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	36,071,127 - 36,081,934 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	36,491,590 - 36,502,389 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ptp4a3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	2,616,806 - 2,626,450 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	10,042,906 - 10,052,480 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	10,042,903 - 10,052,475 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PTP4A3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	2,345,118 - 2,364,672 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	2,345,119 - 2,376,765 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

PTP4A3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	135,663,128 - 135,672,523 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	135,663,149 - 135,671,300 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666039	4,456,641 - 4,500,393 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ptp4a3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624735	14,964,014 - 15,000,477 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624735	14,964,403 - 14,977,441 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ptp4a3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	246,485,116 - 246,516,705 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ptp4a3
153 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	196
Count of miRNA genes:	126
Interacting mature miRNAs:	143
Transcripts:	ENSRNOT00000010224
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	92388565	119280177	Rat
1331728	Bp214	Blood pressure QTL 214	2.825		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	82111245	123048330	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	104186212	135371468	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	31770293	110435881	Rat
70159	Bp61	Blood pressure QTL 61		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	73618702	118618702	Rat
631687	Hcas1	Hepatocarcinoma susceptibility QTL 1	3.9	0.001	liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	7	93302009	131686183	Rat
1357338	Stl17	Serum triglyceride level QTL 17	3.23		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	71621154	114982716	Rat
61397	Bw17	Body weight QTL 17	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	7	95485047	137014596	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	46307490	127866166	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	85043242	130043242	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	85497398	130497398	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	92362341	137014596	Rat
1331723	Bw25	Body weight QTL 25	3.348		body mass (VT:0001259)	body weight (CMO:0000012)	7	96700404	111672180	Rat
2317052	Aia17	Adjuvant induced arthritis QTL 17	2.13		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	7	83626689	128626689	Rat
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	82111382	132099989	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	98549867	137014596	Rat
1559283	Emca4	Estrogen-induced mammary cancer QTL 4	3.7		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	7	63889858	108889858	Rat
7411607	Foco15	Food consumption QTL 15		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	77807807	122807807	Rat
631201	Panci1	Pancreas inflammation QTL 1	0	0.001	pancreas integrity trait (VT:0010560)	percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)	7	73557047	118557047	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	1509236	116977875	Rat
1331768	Kidm10	Kidney mass QTL 10	4.62096		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	82111245	123048330	Rat
2313102	Bmd79	Bone mineral density QTL 79	2.3	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	7	96700404	118618702	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	40540077	123682549	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	49682832	115766396	Rat
10450862	Kidm55	Kidney mass QTL 55	4.9		kidney mass (VT:0002707)	kidney weight (CMO:0000081)	7	72725037	117725037	Rat
1298528	Bp169	Blood pressure QTL 169		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	62963207	107963207	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	100548246	137014596	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	82111245	134948181	Rat
1576303	Ept7	Estrogen-induced pituitary tumorigenesis QTL 7	3.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	7	63889858	108889858	Rat
7411654	Foco25	Food consumption QTL 25	9.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	77807807	122807807	Rat
10450856	Livw4	Liver weight QTL 4	3.8		liver mass (VT:0003402)	liver weight (CMO:0000092)	7	72725037	117725037	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	49682832	115766396	Rat
10402855	Bp379	Blood pressure QTL 379		0.21	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	78682549	123682549	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	49682832	115766396	Rat
631540	Bw9	Body weight QTL 9	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	7	71621154	119349044	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	71827901	136544683	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	141	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001114405	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241729	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241731	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241732	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241733	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008765573	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008765574	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594964	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263855	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263856	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC159432	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000010224 ⟹ ENSRNOP00000010224

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	105,628,029 - 105,660,919 (+)	Ensembl
Rnor_6.0 Ensembl	7	114,997,103 - 115,002,902 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096141 ⟹ ENSRNOP00000078100

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	107,541,047 - 107,549,949 (+)	Ensembl
mRatBN7.2 Ensembl	7	105,652,057 - 105,660,919 (+)	Ensembl

RefSeq Acc Id:

NM_001114405 ⟹ NP_001107877

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	107,544,137 - 107,549,949 (+)	NCBI
mRatBN7.2	7	105,655,106 - 105,660,919 (+)	NCBI
Rnor_6.0	7	114,997,103 - 115,002,902 (+)	NCBI
Rnor_5.0	7	114,892,674 - 114,924,154 (+)	NCBI
RGSC_v3.4	7	111,462,191 - 111,468,045 (+)	RGD
Celera	7	102,062,262 - 102,068,065 (+)	RGD

Sequence:

show sequence

GTGCTGGGGCCCAACTCTGACCAAAGGGGACACTCACTCCTCTATCCACCGATGCAGAGAGGGT
GTCTCCAGCGACAGCCCCATCGAGGACACTGCTCTGCGGCCAGAGTCACCAACCCCAAGTTCTC
GTTGCTCGTTTTTTTTGGTTGTTGTTATTTTTATTTTTGCATCCTCCTAACTACTCCACTCTGA
GGGACAGGACCTTGGAGCTGCCCATCTTGCTGCGGGGTGGGGGAGGGGTGTGTTTGTTTCTTTT
TCTTTTCTTTTTTTTTTTTAGAATTGGGGTTTTTTGGAATCATCCACCACCAGGCAGTTTCCTC
TCCCTCTCCCAAGTTATTTGCACAATATTTGTGCGGGGTGTAGGGGCGAGGTTTTAAGAAGTCT
TTTCTTTTCGGACAAGCACGGGGATCTCACTGGACTTGGTGTGGGGGCCTGGGGGACCCCCCGT
GCAGCCCTTGCTGGCTAGTCCTCTCTGGGTCCCCGGAGGAGGCATGGCCCGCATGAACCGGCCT
GCACCTGTGGAGGTGAGCTACCGACACATGCGTTTCCTCATCACCCACAACCCCAGCAATGCCA
CCCTCAGCACGTTCATCGAGGACCTGAAGAAGTATGGGGCTACCACTGTGGTGCGTGTGTGCGA
AGTGACCTATGACAAGACCCCTCTGGAGAAGGACGGCATCACTGTTGTGGACTGGCCCTTTGAT
GATGGGGCGCCCCCTCCTGGCAAGGTGGTAGAGGACTGGCTGAGCCTGCTGAAGGCCAAGTTCT
ACAATGACCCGGGCAGCTGCGTAGCTGTGCACTGTGTGGCGGGCCTGGGAAGGGCTCCAGTGCT
CGTGGCTCTCGCTCTCATCGAGAGTGGGATGAAGTACGAGGATGCCATCCAGTTCATCCGACAG
AAGCGCCGTGGGGCCATCAACAGCAAGCAGCTCACCTACCTGGAGAAGTACCGGCCTAAGCAGA
GACTGAGATTCAAAGACCCACACACGCACAAGACCAGATGCTGCGTCATGTAGTGCGGGTTCTG
GCTCTGTACGCCCTGTACTCCATTACATCAGGGTCTAAGGAGTCCAACGGCTGTGTGCGTTCCT
GCTCTGTCCCCATCTGTGCCCACGGCTGTCTTTCTGAGGCCGTCCCTGGACCTTCTGCCAGTCC
TGTCCAACCCCTCCACCCACTGCCCGGGCCTCTTCCCCCTGGCCTGTGTATCGCAGGTGGGCTC
TTTTTAACCACTGGGCCGAGAGCCTCAGCGGCGGCGCCCTCACCCTCACCTTTCTCCAGCACCT
TTGTTACCAGGTGCTCTGGACTCTCAAGGCAATAAATCAGGAGCTGTGAAAAAAAAAAAAAAAA
AAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006241729 ⟹ XP_006241791

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	107,540,982 - 107,549,949 (+)	NCBI
mRatBN7.2	7	105,652,026 - 105,660,921 (+)	NCBI
Rnor_6.0	7	114,994,005 - 115,002,902 (+)	NCBI
Rnor_5.0	7	114,892,674 - 114,924,154 (+)	NCBI

Sequence:

show sequence

GGGCATCCGCCCGGAGCCGGCGCCGCTGCGGAGGGCGCGCGCGGGTCCCGGCCCGGCCGGCCGG
CGCATGGAGGCGGCCGCACGCCTGCGGGCGCGGAAGGGCGGCAAGGACTGTCTGTGAGCCGTAG
CACTGACTTGGAGTGGAGTGCTGAGCTGTTCTCAGGGGTAGAAGGTGATTGTGCCTTCTGAAGA
CCAGGGTGCGATTGATGGAGGAGCCCCAGGAGGGCAGCTCTGACTACTGCCGTTCCCAACATCG
TGGGTGCTGCTGCTGAGGAGGCCCGTGCACCTCTGGCCCTCACCATTGCCCTTGCTTCCCAATG
GCCTCTGCTGCCAGGCCGGAGGCCAGCACTGCTGCCTGAGCCCGCTGCCCCTCTCCAGGACTCG
CCGTTCCCTGATGGGGTAACGTGACAGACCGGACCAGAGGCTGCCTGCCTACCACGGCAGAGTT
GGTTGAGTTCAAGTTCATTTTTCCTTTGGTCCTGAGTGCTGGGGCCCAACTCTGACCAAAGGGG
ACACTCACTCCTCTATCCACCGATGCAGAGAGGGTGTCTCCAGCGACAGCCCCATCGAGGACAC
TGCTCTGCGGCCAGAGTCACCAACCCCAAGTTCTCGTTGCTCGTTTTTTTTGGTTGTTGTTATT
TTTATTTTTGCATCCTCCTAACTACTCCACTCTGAGGGACAGGACCTTGGAGCTGCCCATCTTG
CTGCGGGGTGGGGGAGGGGTGTGTTTGTTTCTTTTTCTTTTCTTTTTTTTTTTAGAATTGGGGT
TTTTTGGAATCATCCACCACCAGGCAGCTTCCTCTCCCTCTCCCAAGTTATTTGCACAATATTT
GTGCGGGGTGTAGGGGCGAGGTTTTAAGAAGTCTTTTCTTTTCGGACAAGCACGGGGATCTCAC
TGGACTTGGTGTGGGGGCCTGGGGGACCCCCCGTGCAGCCCTTGCTGGCTAGTCCTCTCTGGGT
CCCCGGAGGAGGCATGGCCCGCATGAACCGGCCTGCACCTGTGGAGGTGAGCTACCGACACATG
CGTTTCCTCATCACCCACAACCCCAGCAATGCCACCCTCAGCACGTTCATCGAGGACCTGAAGA
AGTATGGGGCTACCACTGTGGTGCGTGTGTGCGAAGTGACCTATGACAAGACCCCTCTGGAGAA
GGACGGCATCACTGTTGTGGACTGGCCCTTTGATGATGGGGCGCCCCCTCCTGGCAAGGTGGTA
GAGGACTGGCTGAGCCTGCTGAAGGCCAAGTTCTACAATGACCCGGGCAGCTGCGTAGCTGTGC
ACTGTGTGGCGGGCCTGGGAAGGGCTCCAGTGCTCGTGGCTCTCGCTCTCATCGAGAGTGGGAT
GAAGTACGAGGATGCCATCCAGTTCATCCGACAGAAGCGCCGTGGGGCCATCAACAGCAAGCAG
CTCACCTACCTGGAGAAGTACCGGCCTAAGCAGAGACTGAGATTCAAAGACCCACACACGCACA
AGACCAGATGCTGCGTCATGTAGTGCGGGTTCTGGCTCTGTACGCCCTGTACTCCATTACATCA
GGGTCTAAGGAGTCCAACGGCTGTGTGCGTTCCTGCTCTGTCCCCATCTGTGCCCACGGCTGTC
TTTCTGAGGCCGTCCCTGGACCTTCTGCAGGTCCTGTCCAACCCCTCCACCCACTGCCCGGGCC
TCTTCCCCCTGGCCTGTGTATCGCAGGTGGGCTCTTTTTAACCACTGGGCCGAGAGCCTCAGCG
GCGGCGCCCTCACCCTCACCTTTCTCCAGCACCTTTGTTACCAGGTGCTCTGGACTCTCAAGGC
AATAAATCAGGAGCTGTG

hide sequence

RefSeq Acc Id:

XM_006241731 ⟹ XP_006241793

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	107,539,671 - 107,549,949 (+)	NCBI
mRatBN7.2	7	105,650,640 - 105,660,921 (+)	NCBI
Rnor_6.0	7	114,992,605 - 115,002,902 (+)	NCBI
Rnor_5.0	7	114,892,674 - 114,924,154 (+)	NCBI

Sequence:

show sequence

CTTCTCCGAAAGGCTTGGGGCCCTGCCAGCTCTAGCAGGTGCCCCCAGGCTTAGCTAGAGGCCC
CAGCATGCAGGGGGGCGGGTGTCACTTGGAGCCCCGGTTGCAGCCCTGGCTGGTGCAGTATCTC
AGAAATTGCTGGGCCTGTCGCTAACAAACCCTTTTCTAGACAACTGATTGTGCCTTCTGAAGAC
CAGGGTGCGATTGATGGAGGAGCCCCAGGAGGGCAGCTCTGACTACTGCCGTTCCCAACATCGT
GGGTGCTGCTGCTGAGGAGGCCCGTGCACCTCTGGCCCTCACCATTGCCCTTGCTTCCCAATGG
CCTCTGCTGCCAGGCCGGAGGCCAGCACTGCTGCCTGAGCCCGCTGCCCCTCTCCAGGACTCGC
CGTTCCCTGATGGGGTAACGTGACAGACCGGACCAGAGGCTGCCTGCCTACCACGGCAGAGTTG
GTTGAGTTCAAGTTCATTTTTCCTTTGGTCCTGAGTGCTGGGGCCCAACTCTGACCAAAGGGGA
CACTCACTCCTCTATCCACCGATGCAGAGAGGGTGTCTCCAGCGACAGCCCCATCGAGGACACT
GCTCTGCGGCCAGAGTCACCAACCCCAAGTTCTCGTTGCTCGTTTTTTTTGGTTGTTGTTATTT
TTATTTTTGCATCCTCCTAACTACTCCACTCTGAGGGACAGGACCTTGGAGCTGCCCATCTTGC
TGCGGGGTGGGGGAGGGGTGTGTTTGTTTCTTTTTCTTTTCTTTTTTTTTTTAGAATTGGGGTT
TTTTGGAATCATCCACCACCAGGCAGCTTCCTCTCCCTCTCCCAAGTTATTTGCACAATATTTG
TGCGGGGTGTAGGGGCGAGGTTTTAAGAAGTCTTTTCTTTTCGGACAAGCACGGGGATCTCACT
GGACTTGGTGTGGGGGCCTGGGGGACCCCCCGTGCAGCCCTTGCTGGCTAGTCCTCTCTGGGTC
CCCGGAGGAGGCATGGCCCGCATGAACCGGCCTGCACCTGTGGAGGTGAGCTACCGACACATGC
GTTTCCTCATCACCCACAACCCCAGCAATGCCACCCTCAGCACGTTCATCGAGGACCTGAAGAA
GTATGGGGCTACCACTGTGGTGCGTGTGTGCGAAGTGACCTATGACAAGACCCCTCTGGAGAAG
GACGGCATCACTGTTGTGGACTGGCCCTTTGATGATGGGGCGCCCCCTCCTGGCAAGGTGGTAG
AGGACTGGCTGAGCCTGCTGAAGGCCAAGTTCTACAATGACCCGGGCAGCTGCGTAGCTGTGCA
CTGTGTGGCGGGCCTGGGAAGGGCTCCAGTGCTCGTGGCTCTCGCTCTCATCGAGAGTGGGATG
AAGTACGAGGATGCCATCCAGTTCATCCGACAGAAGCGCCGTGGGGCCATCAACAGCAAGCAGC
TCACCTACCTGGAGAAGTACCGGCCTAAGCAGAGACTGAGATTCAAAGACCCACACACGCACAA
GACCAGATGCTGCGTCATGTAGTGCGGGTTCTGGCTCTGTACGCCCTGTACTCCATTACATCAG
GGTCTAAGGAGTCCAACGGCTGTGTGCGTTCCTGCTCTGTCCCCATCTGTGCCCACGGCTGTCT
TTCTGAGGCCGTCCCTGGACCTTCTGCAGGTCCTGTCCAACCCCTCCACCCACTGCCCGGGCCT
CTTCCCCCTGGCCTGTGTATCGCAGGTGGGCTCTTTTTAACCACTGGGCCGAGAGCCTCAGCGG
CGGCGCCCTCACCCTCACCTTTCTCCAGCACCTTTGTTACCAGGTGCTCTGGACTCTCAAGGCA
ATAAATCAGGAGCTGTG

hide sequence

RefSeq Acc Id:

XM_006241732 ⟹ XP_006241794

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	107,540,996 - 107,549,949 (+)	NCBI
mRatBN7.2	7	105,651,975 - 105,660,921 (+)	NCBI
Rnor_6.0	7	114,994,005 - 115,002,902 (+)	NCBI
Rnor_5.0	7	114,892,674 - 114,924,154 (+)	NCBI

Sequence:

show sequence

GGGCATCCGCCCGGAGCCGGCGCCGCTGCGGAGGGCGCGCGCGGGTCCCGGCCCGGCCGGCCGG
CGCATGGAGGCGGCCGCACGCCTGCGGGCGCGGATTGTGCCTTCTGAAGACCAGGGTGCGATTG
ATGGAGGAGCCCCAGGAGGGCAGCTCTGACTACTGCCGTTCCCAACATCGTGGGTGCTGCTGCT
GAGGAGGCCCGTGCACCTCTGGCCCTCACCATTGCCCTTGCTTCCCAATGGCCTCTGCTGCCAG
GCCGGAGGCCAGCACTGCTGCCTGAGCCCGCTGCCCCTCTCCAGGACTCGCCGTTCCCTGATGG
GGTAACGTGACAGACCGGACCAGAGGCTGCCTGCCTACCACGGCAGAGTTGGTTGAGTTCAAGT
TCATTTTTCCTTTGGTCCTGAGTGCTGGGGCCCAACTCTGACCAAAGGGGACACTCACTCCTCT
ATCCACCGATGCAGAGAGGGTGTCTCCAGCGACAGCCCCATCGAGGACACTGCTCTGCGGCCAG
AGTCACCAACCCCAAGTTCTCGTTGCTCGTTTTTTTTGGTTGTTGTTATTTTTATTTTTGCATC
CTCCTAACTACTCCACTCTGAGGGACAGGACCTTGGAGCTGCCCATCTTGCTGCGGGGTGGGGG
AGGGGTGTGTTTGTTTCTTTTTCTTTTCTTTTTTTTTTTAGAATTGGGGTTTTTTGGAATCATC
CACCACCAGGCAGCTTCCTCTCCCTCTCCCAAGTTATTTGCACAATATTTGTGCGGGGTGTAGG
GGCGAGGTTTTAAGAAGTCTTTTCTTTTCGGACAAGCACGGGGATCTCACTGGACTTGGTGTGG
GGGCCTGGGGGACCCCCCGTGCAGCCCTTGCTGGCTAGTCCTCTCTGGGTCCCCGGAGGAGGCA
TGGCCCGCATGAACCGGCCTGCACCTGTGGAGGTGAGCTACCGACACATGCGTTTCCTCATCAC
CCACAACCCCAGCAATGCCACCCTCAGCACGTTCATCGAGGACCTGAAGAAGTATGGGGCTACC
ACTGTGGTGCGTGTGTGCGAAGTGACCTATGACAAGACCCCTCTGGAGAAGGACGGCATCACTG
TTGTGGACTGGCCCTTTGATGATGGGGCGCCCCCTCCTGGCAAGGTGGTAGAGGACTGGCTGAG
CCTGCTGAAGGCCAAGTTCTACAATGACCCGGGCAGCTGCGTAGCTGTGCACTGTGTGGCGGGC
CTGGGAAGGGCTCCAGTGCTCGTGGCTCTCGCTCTCATCGAGAGTGGGATGAAGTACGAGGATG
CCATCCAGTTCATCCGACAGAAGCGCCGTGGGGCCATCAACAGCAAGCAGCTCACCTACCTGGA
GAAGTACCGGCCTAAGCAGAGACTGAGATTCAAAGACCCACACACGCACAAGACCAGATGCTGC
GTCATGTAGTGCGGGTTCTGGCTCTGTACGCCCTGTACTCCATTACATCAGGGTCTAAGGAGTC
CAACGGCTGTGTGCGTTCCTGCTCTGTCCCCATCTGTGCCCACGGCTGTCTTTCTGAGGCCGTC
CCTGGACCTTCTGCAGGTCCTGTCCAACCCCTCCACCCACTGCCCGGGCCTCTTCCCCCTGGCC
TGTGTATCGCAGGTGGGCTCTTTTTAACCACTGGGCCGAGAGCCTCAGCGGCGGCGCCCTCACC
CTCACCTTTCTCCAGCACCTTTGTTACCAGGTGCTCTGGACTCTCAAGGCAATAAATCAGGAGC
TGTG

hide sequence

RefSeq Acc Id:

XM_008765573 ⟹ XP_008763795

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	107,539,663 - 107,549,949 (+)	NCBI
mRatBN7.2	7	105,650,741 - 105,660,921 (+)	NCBI
Rnor_6.0	7	114,992,605 - 115,002,902 (+)	NCBI

Sequence:

show sequence

CTTCTCCGAAAGGCTTGGGGCCCTGCCAGCTCTAGCAGGTGCCCCCAGGCTTAGCTAGAGGCCC
CAGCATGCAGGGGGGCGGGTGTCACTTGGAGCCCCGGTTGCAGCCCTGGCTGGTGCAGTATCTC
AGAAATTGCTGGGCCTGTCGCTAACAAACCCTTTTCTAGACAACTGAAGGGCGGCAAGGACTGT
CTGTGAGCCGTAGCACTGACTTGGAGTGGAGTGCTGAGCTGTTCTCAGGGGTAGAAGGTGATTG
TGCCTTCTGAAGACCAGGGTGCGATTGATGGAGGAGCCCCAGGAGGGCAGCTCTGACTACTGCC
GTTCCCAACATCGTGGGTGCTGCTGCTGAGGAGGCCCGTGCACCTCTGGCCCTCACCATTGCCC
TTGCTTCCCAATGGCCTCTGCTGCCAGGCCGGAGGCCAGCACTGCTGCCTGAGCCCGCTGCCCC
TCTCCAGGACTCGCCGTTCCCTGATGGGGTAACGTGACAGACCGGACCAGAGGCTGCCTGCCTA
CCACGGCAGAGTTGGTTGAGTTCAAGTTCATTTTTCCTTTGGTCCTGAGTGCTGGGGCCCAACT
CTGACCAAAGGGGACACTCACTCCTCTATCCACCGATGCAGAGAGGGTGTCTCCAGCGACAGCC
CCATCGAGGACACTGCTCTGCGGCCAGAGTCACCAACCCCAAGTTCTCGTTGCTCGTTTTTTTT
GGTTGTTGTTATTTTTATTTTTGCATCCTCCTAACTACTCCACTCTGAGGGACAGGACCTTGGA
GCTGCCCATCTTGCTGCGGGGTGGGGGAGGGGTGTGTTTGTTTCTTTTTCTTTTCTTTTTTTTT
TTAGAATTGGGGTTTTTTGGAATCATCCACCACCAGGCAGCTTCCTCTCCCTCTCCCAAGTTAT
TTGCACAATATTTGTGCGGGGTGTAGGGGCGAGGTTTTAAGAAGTCTTTTCTTTTCGGACAAGC
ACGGGGATCTCACTGGACTTGGTGTGGGGGCCTGGGGGACCCCCCGTGCAGCCCTTGCTGGCTA
GTCCTCTCTGGGTCCCCGGAGGAGGCATGGCCCGCATGAACCGGCCTGCACCTGTGGAGGTGAG
CTACCGACACATGCGTTTCCTCATCACCCACAACCCCAGCAATGCCACCCTCAGCACGTTCATC
GAGGACCTGAAGAAGTATGGGGCTACCACTGTGGTGCGTGTGTGCGAAGTGACCTATGACAAGA
CCCCTCTGGAGAAGGACGGCATCACTGTTGTGGACTGGCCCTTTGATGATGGGGCGCCCCCTCC
TGGCAAGGTGGTAGAGGACTGGCTGAGCCTGCTGAAGGCCAAGTTCTACAATGACCCGGGCAGC
TGCGTAGCTGTGCACTGTGTGGCGGGCCTGGGAAGGGCTCCAGTGCTCGTGGCTCTCGCTCTCA
TCGAGAGTGGGATGAAGTACGAGGATGCCATCCAGTTCATCCGACAGAAGCGCCGTGGGGCCAT
CAACAGCAAGCAGCTCACCTACCTGGAGAAGTACCGGCCTAAGCAGAGACTGAGATTCAAAGAC
CCACACACGCACAAGACCAGATGCTGCGTCATGTAGTGCGGGTTCTGGCTCTGTACGCCCTGTA
CTCCATTACATCAGGGTCTAAGGAGTCCAACGGCTGTGTGCGTTCCTGCTCTGTCCCCATCTGT
GCCCACGGCTGTCTTTCTGAGGCCGTCCCTGGACCTTCTGCAGGTCCTGTCCAACCCCTCCACC
CACTGCCCGGGCCTCTTCCCCCTGGCCTGTGTATCGCAGGTGGGCTCTTTTTAACCACTGGGCC
GAGAGCCTCAGCGGCGGCGCCCTCACCCTCACCTTTCTCCAGCACCTTTGTTACCAGGTGCTCT
GGACTCTCAAGGCAATAAATCAGGAGCTGTG

hide sequence

RefSeq Acc Id:

XM_008765574 ⟹ XP_008763796

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	107,540,397 - 107,549,949 (+)	NCBI
mRatBN7.2	7	105,651,404 - 105,660,921 (+)	NCBI
Rnor_6.0	7	114,992,808 - 115,002,902 (+)	NCBI

Sequence:

show sequence

TTTTCCTAGCTACCTGGGACTGGGATCAGCAGGGTCTCTGGGGGTGGGCAAATCTCCAAACATG
GTCTAGCCCCCTGGCTGTGTGACTTGGGTGATCTTCTTAACATCTCTGAGTTGCTGGATGCCAG
TGCCTTGTAGAGGGTTCAGTGTTTACTGTCAGGATGGGAACTAGTGGAACAGCTGAGGCCGTGG
GATTGGTCAGCATCAATGCAGTTACCGTGGTGGGTTTATAGGGTGGTATAATCTGGGGATCTCA
GGTGGCTGCCTGGCTTTCTGGGGGTGAGTCAGGATGGGGCTGCAGTGGGATGCTCCAGCCCTAC
TTAATCTGTGCCGGGCGAGAATGGGGGACAGTAGGCTCTGCTGTGTGGGGCTGGCTAATGAGAC
TTCTCTCGGGAGTATTAGGAGCATGCCCTTTCCTGGCTTCGGCCCAGCCTTTCAGGGACCATTC
CTCTCCCCAGCACCAACTACTGATTGCAGGGCCAGGCCTCTGTCTGGGAGCCGGGCTTGGGCCA
GGGTTCCCAGCAAGGCAAAGTCTCTGGGGATTCTGTGAGCCGGAACTCAACAAGCCCAGCTCCA
GAAGGCTCCCAGGGCCATGCAGCCACTGGGGCAGGTGTGGACTGACACGCTGGAGAGCATAGGG
TTCCTGCCTGGGATGCCCCAGGGCAAAACCAGGATTCTGCCTGGTCAGTGGAGCCCAGGAGAAG
ACCCTGCTAAGGGGATGCCCTGGAAGGCTTCAGGAGAGCTGGATTGTGCCTTCTGAAGACCAGG
GTGCGATTGATGGAGGAGCCCCAGGAGGGCAGCTCTGACTACTGCCGTTCCCAACATCGTGGGT
GCTGCTGCTGAGGAGGCCCGTGCACCTCTGGCCCTCACCATTGCCCTTGCTTCCCAATGGCCTC
TGCTGCCAGGCCGGAGGCCAGCACTGCTGCCTGAGCCCGCTGCCCCTCTCCAGGACTCGCCGTT
CCCTGATGGGGTAACGTGACAGACCGGACCAGAGGCTGCCTGCCTACCACGGCAGAGTTGGTTG
AGTTCAAGTTCATTTTTCCTTTGGTCCTGAGTGCTGGGGCCCAACTCTGACCAAAGGGGACACT
CACTCCTCTATCCACCGATGCAGAGAGGGTGTCTCCAGCGACAGCCCCATCGAGGACACTGCTC
TGCGGCCAGAGTCACCAACCCCAAGTTCTCGTTGCTCGTTTTTTTTGGTTGTTGTTATTTTTAT
TTTTGCATCCTCCTAACTACTCCACTCTGAGGGACAGGACCTTGGAGCTGCCCATCTTGCTGCG
GGGTGGGGGAGGGGTGTGTTTGTTTCTTTTTCTTTTCTTTTTTTTTTTAGAATTGGGGTTTTTT
GGAATCATCCACCACCAGGCAGCTTCCTCTCCCTCTCCCAAGTTATTTGCACAATATTTGTGCG
GGGTGTAGGGGCGAGGTTTTAAGAAGTCTTTTCTTTTCGGACAAGCACGGGGATCTCACTGGAC
TTGGTGTGGGGGCCTGGGGGACCCCCCGTGCAGCCCTTGCTGGCTAGTCCTCTCTGGGTCCCCG
GAGGAGGCATGGCCCGCATGAACCGGCCTGCACCTGTGGAGGTGAGCTACCGACACATGCGTTT
CCTCATCACCCACAACCCCAGCAATGCCACCCTCAGCACGTTCATCGAGGACCTGAAGAAGTAT
GGGGCTACCACTGTGGTGCGTGTGTGCGAAGTGACCTATGACAAGACCCCTCTGGAGAAGGACG
GCATCACTGTTGTGGACTGGCCCTTTGATGATGGGGCGCCCCCTCCTGGCAAGGTGGTAGAGGA
CTGGCTGAGCCTGCTGAAGGCCAAGTTCTACAATGACCCGGGCAGCTGCGTAGCTGTGCACTGT
GTGGCGGGCCTGGGAAGGGCTCCAGTGCTCGTGGCTCTCGCTCTCATCGAGAGTGGGATGAAGT
ACGAGGATGCCATCCAGTTCATCCGACAGAAGCGCCGTGGGGCCATCAACAGCAAGCAGCTCAC
CTACCTGGAGAAGTACCGGCCTAAGCAGAGACTGAGATTCAAAGACCCACACACGCACAAGACC
AGATGCTGCGTCATGTAGTGCGGGTTCTGGCTCTGTACGCCCTGTACTCCATTACATCAGGGTC
TAAGGAGTCCAACGGCTGTGTGCGTTCCTGCTCTGTCCCCATCTGTGCCCACGGCTGTCTTTCT
GAGGCCGTCCCTGGACCTTCTGCAGGTCCTGTCCAACCCCTCCACCCACTGCCCGGGCCTCTTC
CCCCTGGCCTGTGTATCGCAGGTGGGCTCTTTTTAACCACTGGGCCGAGAGCCTCAGCGGCGGC
GCCCTCACCCTCACCTTTCTCCAGCACCTTTGTTACCAGGTGCTCTGGACTCTCAAGGCAATAA
ATCAGGAGCTGTG

hide sequence

RefSeq Acc Id:

XM_063263855 ⟹ XP_063119925

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	107,518,220 - 107,549,949 (+)	NCBI

RefSeq Acc Id:

XM_063263856 ⟹ XP_063119926

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	107,526,205 - 107,549,949 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001107877	(Get FASTA)	NCBI Sequence Viewer
	XP_006241791	(Get FASTA)	NCBI Sequence Viewer
	XP_006241793	(Get FASTA)	NCBI Sequence Viewer
	XP_006241794	(Get FASTA)	NCBI Sequence Viewer
	XP_008763795	(Get FASTA)	NCBI Sequence Viewer
	XP_008763796	(Get FASTA)	NCBI Sequence Viewer
	XP_063119925	(Get FASTA)	NCBI Sequence Viewer
	XP_063119926	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI59433	(Get FASTA)	NCBI Sequence Viewer
	EDM16108	(Get FASTA)	NCBI Sequence Viewer
	EDM16109	(Get FASTA)	NCBI Sequence Viewer
	EDM16110	(Get FASTA)	NCBI Sequence Viewer
	EDM16111	(Get FASTA)	NCBI Sequence Viewer
	EDM16112	(Get FASTA)	NCBI Sequence Viewer
	EDM16113	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000078100
	ENSRNOP00000078100.1

RefSeq Acc Id:	NP_001107877 ⟸ NM_001114405
- UniProtKB:	B0K032 (UniProtKB/TrEMBL), A0A8I5Y855 (UniProtKB/TrEMBL), F7EWD1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARMNRPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGIT VVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGSCVAVHCVAGLGRAPVLVALALIESGMKYED AIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM hide sequence

RefSeq Acc Id:	XP_006241793 ⟸ XM_006241731
- Peptide Label:	isoform X1
- UniProtKB:	B0K032 (UniProtKB/TrEMBL), A0A8I5Y855 (UniProtKB/TrEMBL), F7EWD1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARMNRPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGIT VVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGSCVAVHCVAGLGRAPVLVALALIESGMKYED AIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM hide sequence

RefSeq Acc Id:	XP_006241791 ⟸ XM_006241729
- Peptide Label:	isoform X1
- UniProtKB:	B0K032 (UniProtKB/TrEMBL), A0A8I5Y855 (UniProtKB/TrEMBL), F7EWD1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARMNRPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGIT VVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGSCVAVHCVAGLGRAPVLVALALIESGMKYED AIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM hide sequence

RefSeq Acc Id:	XP_006241794 ⟸ XM_006241732
- Peptide Label:	isoform X1
- UniProtKB:	B0K032 (UniProtKB/TrEMBL), A0A8I5Y855 (UniProtKB/TrEMBL), F7EWD1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARMNRPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGIT VVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGSCVAVHCVAGLGRAPVLVALALIESGMKYED AIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM hide sequence

RefSeq Acc Id:	XP_008763795 ⟸ XM_008765573
- Peptide Label:	isoform X1
- UniProtKB:	B0K032 (UniProtKB/TrEMBL), A0A8I5Y855 (UniProtKB/TrEMBL), F7EWD1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARMNRPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGIT VVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGSCVAVHCVAGLGRAPVLVALALIESGMKYED AIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM hide sequence

RefSeq Acc Id:	XP_008763796 ⟸ XM_008765574
- Peptide Label:	isoform X1
- UniProtKB:	B0K032 (UniProtKB/TrEMBL), A0A8I5Y855 (UniProtKB/TrEMBL), F7EWD1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARMNRPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGIT VVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGSCVAVHCVAGLGRAPVLVALALIESGMKYED AIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM hide sequence

Ensembl Acc Id:

ENSRNOP00000010224 ⟸ ENSRNOT00000010224

Ensembl Acc Id:

ENSRNOP00000078100 ⟸ ENSRNOT00000096141

RefSeq Acc Id:	XP_063119925 ⟸ XM_063263855
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5Y855 (UniProtKB/TrEMBL), B0K032 (UniProtKB/TrEMBL), F7EWD1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063119926 ⟸ XM_063263856
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5Y855 (UniProtKB/TrEMBL), B0K032 (UniProtKB/TrEMBL), F7EWD1 (UniProtKB/TrEMBL)

Protein Domains

Tyrosine specific protein phosphatases Tyrosine-protein phosphatase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B0K032-F1-model_v2	AlphaFold	B0K032	1-173	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308687	AgrOrtholog
BioCyc Gene	G2FUF-33047	BioCyc
Ensembl Genes	ENSRNOG00000007628	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000096141	ENTREZGENE
	ENSRNOT00000096141.2	UniProtKB/TrEMBL
Gene3D-CATH	3.90.190.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:9092581	IMAGE-MGC_LOAD
InterPro	Dual-sp/Tyr_phosphatase	UniProtKB/TrEMBL
	Prot-tyrosine_phosphatase-like	UniProtKB/TrEMBL
	PTP	UniProtKB/TrEMBL
	Tyr_Pase_cat	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_DUAL_dom	UniProtKB/TrEMBL
KEGG Report	rno:362930	UniProtKB/TrEMBL
MGC_CLONE	MGC:188757	IMAGE-MGC_LOAD
NCBI Gene	362930	ENTREZGENE
PANTHER	TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE	UniProtKB/TrEMBL
Pfam	Tc-R-P	UniProtKB/TrEMBL
PhenoGen	Ptp4a3	PhenoGen
PROSITE	TYR_PHOSPHATASE_2	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_DUAL	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000007628	RatGTEx
SMART	PTPc_motif	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52799	UniProtKB/TrEMBL
UniProt	A0A8I5Y855	ENTREZGENE, UniProtKB/TrEMBL
	B0K032	ENTREZGENE, UniProtKB/TrEMBL
	F7EWD1	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-04-03	Ptp4a3	protein tyrosine phosphatase 4A3	Ptp4a3	protein tyrosine phosphatase type IVA, member 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-02-22	Ptp4a3	protein tyrosine phosphatase type IVA, member 3	Ptp4a3	protein tyrosine phosphatase 4a3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Ptp4a3	protein tyrosine phosphatase 4a3	Ptp4a3_predicted	protein tyrosine phosphatase 4a3 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Ptp4a3_predicted	protein tyrosine phosphatase 4a3 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD