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Gene: Ddx23 (DEAD-box helicase 23) Rattus norvegicus

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Symbol:

Ddx23

Name:

DEAD-box helicase 23

RGD ID:

1308685

Description:

Predicted to enable mRNA binding activity. Predicted to be involved in R-loop processing and mRNA splicing, via spliceosome. Predicted to be located in chromatin and nucleus. Predicted to be part of U4/U6 x U5 tri-snRNP complex; U5 snRNP; and catalytic step 2 spliceosome. Orthologous to human DDX23 (DEAD-box helicase 23); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

DEAD (Asp-Glu-Ala-Asp) box polypeptide 23; LOC300208; probable ATP-dependent RNA helicase DDX23

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DDX23 (DEAD-box helicase 23)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther
Mus musculus (house mouse):	Ddx23 (DEAD box helicase 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ddx23 (DEAD-box helicase 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DDX23 (DEAD-box helicase 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DDX23 (DEAD-box helicase 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ddx23 (DEAD-box helicase 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DDX23 (DEAD-box helicase 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DDX23 (DEAD-box helicase 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ddx23 (DEAD-box helicase 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ddx23 (DEAD-box helicase 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	DDX23 (DEAD-box helicase 23)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ddx23 (DEAD box helicase 23)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ddx23 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 23)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG10333	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PRP28	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ddx-23	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ddx23	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ddx23	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	131,676,636 - 131,693,917 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	131,676,636 - 131,689,074 (-)	Ensembl				GRCr8
mRatBN7.2	7	129,797,620 - 129,814,909 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	129,797,614 - 129,814,949 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	131,604,960 - 131,622,123 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	133,830,506 - 133,847,669 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	133,743,008 - 133,760,171 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	140,325,453 - 140,342,730 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	140,325,431 - 140,342,727 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	114,828,726 - 114,846,002 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	137,394,834 - 137,412,075 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	126,287,854 - 126,305,095 (-)	NCBI		Celera
RGSC_v3.1	7	137,471,818 - 137,488,539 (-)	NCBI
Cytogenetic Map	7	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

complex cortical dysplasia with other brain malformations 14B (ISO)

Failure to Thrive (ISO)

Fetal Growth Retardation (ISO)

genetic disease (ISO)

intellectual disability (ISO)

NEURODEVELOPMENTAL DISORDER WITH VISUAL DEFECTS AND BRAIN ANOMALIES (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

2,2'-Methylenebis(4-methyl-6-tert-butylphenol) (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,6-tribromophenol (ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

3-chloropropane-1,2-diol (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

acrolein (ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

C60 fullerene (EXP)

cadmium dichloride (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

dextran sulfate (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP)

ethanol (ISO)

Evodiamine (ISO)

flutamide (EXP)

FR900359 (ISO)

indometacin (ISO)

ivermectin (ISO)

lead diacetate (ISO)

leflunomide (ISO)

menadione (ISO)

N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (ISO)

nickel atom (ISO)

nitrates (ISO)

ozone (ISO)

paclitaxel (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

thiram (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

trovafloxacin (ISO)

tungsten (ISO)

tunicamycin (ISO)

vincaleukoblastine (ISO)

Yessotoxin (ISO)

zinc sulfate (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

mRNA processing (IEA)

mRNA splicing, via spliceosome (IBA)

R-loop processing (IEA,ISO)

RNA splicing (IEA)

Cellular Component

catalytic step 2 spliceosome (IBA,IEA,ISO)

chromatin (IEA,ISO)

nucleolus (IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IEA,ISO)

U4/U6 x U5 tri-snRNP complex (IEA,ISO)

U5 snRNP (IEA,ISO)

Molecular Function

ATP binding (IEA)

helicase activity (IEA,ISO)

hydrolase activity (IEA)

mRNA binding (IBA)

nucleic acid binding (IEA)

nucleotide binding (IEA)

protein binding (ISO)

RNA helicase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

spliceosome pathway (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Functions of the DExD/H-box proteins in nuclear pre-mRNA splicing.	Chang TH, etal., Biochim Biophys Acta. 2013 Aug;1829(8):764-74. doi: 10.1016/j.bbagrm.2013.02.006. Epub 2013 Feb 21.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation
7.	The spliceosome: design principles of a dynamic RNP machine.	Wahl MC, etal., Cell. 2009 Feb 20;136(4):701-18. doi: 10.1016/j.cell.2009.02.009.

Additional References at PubMed

PMID:9409622	PMID:9539711	PMID:11991638	PMID:12477932	PMID:19199708	PMID:22681889	PMID:28076779

Genomics

Comparative Map Data

Ddx23
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	131,676,636 - 131,693,917 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	131,676,636 - 131,689,074 (-)	Ensembl				GRCr8
mRatBN7.2	7	129,797,620 - 129,814,909 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	129,797,614 - 129,814,949 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	131,604,960 - 131,622,123 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	133,830,506 - 133,847,669 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	133,743,008 - 133,760,171 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	140,325,453 - 140,342,730 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	140,325,431 - 140,342,727 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	114,828,726 - 114,846,002 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	137,394,834 - 137,412,075 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	126,287,854 - 126,305,095 (-)	NCBI		Celera
RGSC_v3.1	7	137,471,818 - 137,488,539 (-)	NCBI
Cytogenetic Map	7	q36	NCBI

DDX23
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	48,829,756 - 48,852,163 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	48,829,756 - 48,852,842 (-)	Ensembl			hg38	GRCh38
GRCh37	12	49,223,539 - 49,245,946 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	47,509,806 - 47,532,224 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	47,509,806 - 47,532,224	NCBI
Celera	12	48,019,665 - 48,042,067 (-)	NCBI		Celera
Cytogenetic Map	12	q13.12	NCBI
HuRef	12	46,256,781 - 46,278,800 (-)	NCBI		HuRef
CHM1_1	12	49,189,355 - 49,211,761 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	48,791,783 - 48,814,355 (-)	NCBI		T2T-CHM13v2.0

Ddx23
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	98,543,012 - 98,560,808 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	98,543,015 - 98,560,775 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	98,645,379 - 98,662,928 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	98,645,134 - 98,662,894 (-)	Ensembl			mm10	GRCm38
MGSCv37	15	98,475,938 - 98,493,320 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	98,473,541 - 98,490,923 (-)	NCBI		MGSCv36	mm8
Celera	15	100,794,107 - 100,811,425 (-)	NCBI		Celera
Cytogenetic Map	15	F1	NCBI
cM Map	15	54.65	NCBI

Ddx23
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955500	7,685,954 - 7,695,765 (-)	Ensembl
ChiLan1.0	NW_004955500	7,685,954 - 7,698,880 (-)	NCBI	ChiLan1.0	ChiLan1.0

DDX23
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	45,329,615 - 45,351,501 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	45,326,375 - 45,348,262 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	39,896,354 - 39,917,195 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	40,774,975 - 40,796,466 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	40,774,975 - 40,796,466 (+)	Ensembl			panPan2	panpan1.1

DDX23
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	5,690,452 - 5,704,762 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	5,693,931 - 5,704,778 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	40,553,181 - 40,567,447 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	5,741,282 - 5,755,600 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	5,744,758 - 5,755,600 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	5,705,190 - 5,719,452 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	5,695,245 - 5,709,552 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	40,945,432 - 40,959,725 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ddx23
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	66,481,233 - 66,497,853 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936512	6,666,814 - 6,682,728 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936512	6,666,972 - 6,682,596 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DDX23
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	14,888,958 - 14,899,174 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	14,888,951 - 14,909,741 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	15,182,736 - 15,185,393 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DDX23
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	45,071,884 - 45,092,287 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	45,071,611 - 45,092,646 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	201,054,301 - 201,075,103 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ddx23
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624816	3,320,065 - 3,334,559 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624816	3,320,218 - 3,334,198 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ddx23
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	271,471,717 - 271,488,946 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ddx23
67 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	156
Count of miRNA genes:	124
Interacting mature miRNAs:	137
Transcripts:	ENSRNOT00000055529
Prediction methods:	Miranda, Pita, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	82111382	132099989	Rat
1354582	Stl11	Serum triglyceride level QTL 11	3.42		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	121393075	137014596	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	98549867	137014596	Rat
1300112	Bp183	Blood pressure QTL 183	3.51		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	119280025	135560836	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	104186212	135371468	Rat
631687	Hcas1	Hepatocarcinoma susceptibility QTL 1	3.9	0.001	liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	7	93302009	131686183	Rat
1331748	Bp215	Blood pressure QTL 215	4.043		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	110725024	135371468	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	100548246	137014596	Rat
61397	Bw17	Body weight QTL 17	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	7	95485047	137014596	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	82111245	134948181	Rat
1358914	Bp266	Blood pressure QTL 266			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	115313999	136544683	Rat
2299163	Iddm34	Insulin dependent diabetes mellitus QTL 34	2.71		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	7	116269196	132020414	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	92362341	137014596	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	71827901	136544683	Rat

Markers in Region

D7Rat3

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	7	131,686,183 - 131,686,295 (+)	Marker Load Pipeline
mRatBN7.2	7	129,807,172 - 129,807,284 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	140,335,001 - 140,335,112	NCBI	Rnor6.0
Rnor_5.0	X	114,838,279 - 114,838,390	UniSTS	Rnor5.0
RGSC_v3.4	7	137,404,381 - 137,404,493	RGD	RGSC3.4
RGSC_v3.4	7	137,404,382 - 137,404,493	UniSTS	RGSC3.4
Celera	7	126,297,402 - 126,297,513	UniSTS
RGSC_v3.1	7	137,480,819 - 137,480,930	RGD
RH 3.4 Map	7	1077.1	UniSTS
RH 3.4 Map	7	1077.1	RGD
SHRSP x BN Map	7	86.2299	UniSTS
SHRSP x BN Map	7	86.2299	RGD
FHH x ACI Map	7	71.32	RGD
Cytogenetic Map	7	q36	UniSTS

RH127810

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	129,797,915 - 129,798,102 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	140,325,744 - 140,325,930	NCBI	Rnor6.0
Rnor_5.0	X	114,829,022 - 114,829,208	UniSTS	Rnor5.0
RGSC_v3.4	7	137,395,125 - 137,395,311	UniSTS	RGSC3.4
Celera	7	126,288,145 - 126,288,331	UniSTS
RH 3.4 Map	7	1086.5	UniSTS
Cytogenetic Map	7	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	356	192	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106793	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006257343	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC129405	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC099148	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC169082	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB612721	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO570626	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000089612 ⟹ ENSRNOP00000072026

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	131,676,636 - 131,689,074 (-)	Ensembl
mRatBN7.2 Ensembl	7	129,797,614 - 129,814,949 (-)	Ensembl
Rnor_6.0 Ensembl	7	140,325,431 - 140,342,727 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000167371 ⟹ ENSRNOP00000100075

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	131,676,685 - 131,689,074 (-)	Ensembl

RefSeq Acc Id:

NM_001106793 ⟹ NP_001100263

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	131,676,636 - 131,693,877 (-)	NCBI
mRatBN7.2	7	129,797,625 - 129,814,866 (-)	NCBI
Rnor_6.0	7	140,325,453 - 140,342,694 (-)	NCBI
Rnor_5.0	X	114,828,726 - 114,846,002 (-)	NCBI
RGSC_v3.4	7	137,394,834 - 137,412,075 (-)	RGD
Celera	7	126,287,854 - 126,305,095 (-)	RGD

Sequence:

show sequence

GAAAGATGGCGACTGTTCGGCGACGTTGAGGCCGCGTTAGGCGGTTCAGGCGCGGGGTGATGGC
AGGAGAACTGGCTGACAAGAAGGACCGAGACGCATCACCCAAGGAAGAAAGGAAGCGATCGCGG
ACTCCTGAAAGAGATCGCGATAGAGACCGGGACCGGAAGTCCTCCCCATCTAAAGACCGGAAGA
GGCATCGCTCACGGGATAGGCGTCGAGGAGGTAGTCGTTCTCGCTCTCGGTCCCGTTCCAAGTC
TACAGAGAGGGAACGACGGCACAAAGAACGGGAACGAGATAAAGAACGGGATCGGAGTAAGAAG
GAGCGGGAGCGGGACAAGGATGGCCACCGGCGGGACAAGGACCGCAAGAGATCCAGCTTGTCTC
CTGGTCGAGGAAAAGATTTCAAGTCTCGGAAGGACAGAGATTCTAAGAAGGGTGACGAGGATGA
GCATGGTGACAAGAGGCCTAAGATCCAGCCACTGTCCCTGGAGGAACTTCTGGCCAAGAAAAAG
GCTGAGGAAGAAGCTGAAGCTAAGCCTAAATTCCTCTCCAAAGCAGAGCGAGAGGCTGAAGCTC
TGAAGCGGCGGCAGCAGGAGGTGGAGGAGCGACAGAAGATGCTCGAAGAAGAGAGGAAGAAGAG
GAAACAGTTCCAGGATTTGGGCAGGAAGATGCTGGAAGACCCTCAGGAAAGGGAACGGAGGGAA
CGCAGGGAAAGGATGGAGCGAGAGACCAATGGCAACGAGGATGAGGAGGGCCGGCAGAAGATCC
GGGAGGAGAAGGACAAGAGCAAGGAGCTGCACGCTATTAAGGAGCGTTACCTGGGTGGCATCAA
AAAACGGCGCCGGACAAGGCATCTCAATGACCGCAAGTTTGTGTTTGAGTGGGATGCGTCTGAA
GACACCTCCATTGACTACAACCCCCTGTACAAAGAACGGCACCAGGTGCAGCTGTTGGGGCGGG
GCTTCATTGCGGGCATTGACCTAAAGCAGCAGAAGCGAGAACAGTCACGTTTCTATGGAGACCT
AATGGAAAAGAGACGAACCCTGGAAGAAAAGGAGCAGGAGGAAGCAAGACTCCGCAAACTTCGT
AAGAAGGAAGCCAAGCAACGCTGGGATGATCGCCACTGGTCCCAGAAGAAGTTAGATGAGATGA
CAGACAGGGACTGGCGGATCTTTCGGGAAGACTATAGCATCACCACCAAAGGTGGCAAGATTCC
CAATCCTATTCGGTCCTGGAAAGATTCGTCTCTGCCCCCACATATCTTGGAAGTCATTGATAAG
TGTGGCTACAAGGAGCCAACACCTATCCAGCGTCAGGCCATTCCCATTGGGCTTCAGAATCGTG
ACATCATTGGCGTGGCTGAGACTGGCAGTGGCAAGACAGCAGCCTTCCTCATCCCATTACTGGT
CTGGATCACCACACTTCCCAAAATTGACAGGATCGAAGAGTCCGACCAGGGCCCTTATGCCATC
ATCCTGGCTCCCACCCGTGAATTGGCTCAGCAGATCGAGGAAGAGACCATCAAGTTCGGAAAGC
CACTAGGTATCCGCACTGTGGCTGTCATTGGTGGCATCTCCAGAGAGGACCAAGGCTTCAGGCT
ACGCATGGGTTGTGAGATTGTGATCGCCACCCCAGGACGTCTGATTGACGTGCTGGAGAACCGT
TACCTGGTGCTCAGCCGCTGCACCTATGTGGTTCTGGATGAGGCCGACAGGATGATTGACATGG
GCTTCGAGCCAGATGTGCAGAAGATCCTGGAGCACATGCCTGTCAGCAACCAGAAGCCGGACAC
GGACGAGGCCGAGGACCCCGAGAAGATGTTAGCCAACTTTGAATCAGGAAAACACAAGTACCGT
CAAACAGTCATGTTCACGGCTACCATGCCTCCAGCGGTGGAGCGTCTAGCCAGGAGCTATCTTC
GGCGGCCTGCTGTGGTGTACATTGGCTCTGCAGGCAAGCCCCATGAGCGGGTGGAACAGAAGGT
CTTTCTCATGTCGGAGTCAGAAAAGAGGAAAAAGCTGCTGGCAATCCTGGAACAAGGTTTTGAT
CCACCCATCATCATCTTTGTCAACCAGAAGAAGGGTTGCGACGTGTTGGCCAAGTCTCTGGAGA
AGATGGGGTACAACGCCTGTACACTGCATGGTGGCAAAGGCCAGGAGCAGCGAGAATTCGCATT
GTCCAACCTCAAGGCTGGAGCCAAGGATATTCTGGTGGCTACAGATGTGGCTGGTCGTGGTATC
GATATCCAAGACGTATCTATGGTTGTCAACTACGACATGGCCAAAAACATTGAAGATTACATTC
ACCGAATTGGCCGCACAGGAAGAGCAGGCAAGAGTGGTGTAGCCATCACCTTCCTCACCAAAGA
GGACTCAGCCGTGTTCTATGAACTGAAGCAAGCCATCCTGGAGAGCCCAGTGTCCTCTTGCCCT
CCAGAGCTGGCAAACCACCCAGATGCCCAGCACAAGCCAGGCACCATCCTTACCAAGAAGCGCA
GGGAAGAGACCATCTTTGCCTGACACAGCACCTGAGTGGATTTGAAGCCATGCTCTGAAACTGG
TGCCTGTCCTAAGCCCTCATGACCCCTCCAGGCTCTTGTCCTTGGCTCATGGGTCTTAGGAAGC
AGCCAGAGTCCCTGGTTTGGAGCCTGTGAGGTGGGCTCCAAGGGAACAGGAAGGGCTGTAGGAG
GCAGGAGCAGCACGCTATGGGGCAGCTGCCTAGCACGATCTCCAGCCTGAACAAACACCTGGTC
ACCTGGAGGGGACTTCCTCAGCACACCTGTGTGACTGTACAGCAGTAGTTGCCCTGAGTGACCC
AGGGGATCTGGCATCATGAGGATTGTGGACCTTGGACTCTGTCACTCTGACAACTGGTTTCCCA
TTCGGAGTTTAAAGCAGGTTGAGCGCCCTTAGAACTGCGCAGCCCTGTGCCACACAACCTCTGT
GCCACGGGTGCTGTGCACTCTGGGCATCCCTCCTCTCCCCGCCCCTCGGAGTTTAAGTCAGTAA
TTTGTTTTCTATTCTCTGAGAAGATAAGTTTGTATGTTCTGAGAATAAATACATGAATATTAAA
GTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006257343 ⟹ XP_006257405

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	131,676,639 - 131,693,917 (-)	NCBI
mRatBN7.2	7	129,797,620 - 129,814,909 (-)	NCBI
Rnor_6.0	7	140,325,456 - 140,342,730 (-)	NCBI
Rnor_5.0	X	114,828,726 - 114,846,002 (-)	NCBI

Sequence:

show sequence

GCGCGGCCAGGGTGCTCCTCCGTGATCAGGAAACGCGAAAGATGGCGACTGTTCGGCGACGTTG
AGGCCGCGTTAGGCGGTTCAGGCGCGGGGTGGTGAGTCTTGGCGGTGGAGGCGGCTCCCACGAG
TTTGGAGAGTGGATGGCAGGAGAACTGGCTGACAAGAAGGACCGAGACGCATCACCCAAGGAAG
AAAGGAAGCGATCGCGGACTCCTGAAAGAGATCGCGATAGAGACCGGGACCGGAAGTCCTCCCC
ATCTAAAGACCGGAAGAGGCATCGCTCACGGGATAGGCGTCGAGGAGGTAGTCGTTCTCGCTCT
CGGTCCCGTTCCAAGTCTACAGAGAGGGAACGACGGCACAAAGAACGGGAACGAGATAAAGAAC
GGGATCGGAGTAAGAAGGAGCGGGAGCGGGACAAGGATGGCCACCGGCGGGACAAGGACCGCAA
GAGATCCAGCTTGTCTCCTGGTCGAGGAAAAGATTTCAAGTCTCGGAAGGACAGAGATTCTAAG
AAGGGTGACGAGGATGAGCATGGTGACAAGAGGCCTAAGATCCAGCCACTGTCCCTGGAGGAAC
TTCTGGCCAAGAAAAAGGCTGAGGAAGAAGCTGAAGCTAAGCCTAAATTCCTCTCCAAAGCAGA
GCGAGAGGCTGAAGCTCTGAAGCGGCGGCAGCAGGAGGTGGAGGAGCGACAGAAGATGCTCGAA
GAAGAGAGGAAGAAGAGGAAACAGTTCCAGGATTTGGGCAGGAAGATGCTGGAAGACCCTCAGG
AAAGGGAACGGAGGGAACGCAGGGAAAGGATGGAGCGAGAGACCAATGGCAACGAGGATGAGGA
GGGCCGGCAGAAGATCCGGGAGGAGAAGGACAAGAGCAAGGAGCTGCACGCTATTAAGGAGCGT
TACCTGGGTGGCATCAAAAAACGGCGCCGGACAAGGCATCTCAATGACCGCAAGTTTGTGTTTG
AGTGGGATGCGTCTGAAGACACCTCCATTGACTACAACCCCCTGTACAAAGAACGGCACCAGGT
GCAGCTGTTGGGGCGGGGCTTCATTGCGGGCATTGACCTAAAGCAGCAGAAGCGAGAACAGTCA
CGTTTCTATGGAGACCTAATGGAAAAGAGACGAACCCTGGAAGAAAAGGAGCAGGAGGAAGCAA
GACTCCGCAAACTTCGTAAGAAGGAAGCCAAGCAACGCTGGGATGATCGCCACTGGTCCCAGAA
GAAGTTAGATGAGATGACAGACAGGGACTGGCGGATCTTTCGGGAAGACTATAGCATCACCACC
AAAGGTGGCAAGATTCCCAATCCTATTCGGTCCTGGAAAGATTCGTCTCTGCCCCCACATATCT
TGGAAGTCATTGATAAGTGTGGCTACAAGGAGCCAACACCTATCCAGCGTCAGGCCATTCCCAT
TGGGCTTCAGAATCGTGACATCATTGGCGTGGCTGAGACTGGCAGTGGCAAGACAGCAGCCTTC
CTCATCCCATTACTGGTCTGGATCACCACACTTCCCAAAATTGACAGGATCGAAGAGTCCGACC
AGGGCCCTTATGCCATCATCCTGGCTCCCACCCGTGAATTGGCTCAGCAGATCGAGGAAGAGAC
CATCAAGTTCGGAAAGCCACTAGGTATCCGCACTGTGGCTGTCATTGGTGGCATCTCCAGAGAG
GACCAAGGCTTCAGGCTACGCATGGGTTGTGAGATTGTGATCGCCACCCCAGGACGTCTGATTG
ACGTGCTGGAGAACCGTTACCTGGTGCTCAGCCGCTGCACCTATGTGGTTCTGGATGAGGCCGA
CAGGATGATTGACATGGGCTTCGAGCCAGATGTGCAGAAGATCCTGGAGCACATGCCTGTCAGC
AACCAGAAGCCGGACACGGACGAGGCCGAGGACCCCGAGAAGATGTTAGCCAACTTTGAATCAG
GAAAACACAAGTACCGTCAAACAGTCATGTTCACGGCTACCATGCCTCCAGCGGTGGAGCGTCT
AGCCAGGAGCTATCTTCGGCGGCCTGCTGTGGTGTACATTGGCTCTGCAGGCAAGCCCCATGAG
CGGGTGGAACAGAAGGTCTTTCTCATGTCGGAGTCAGAAAAGAGGAAAAAGCTGCTGGCAATCC
TGGAACAAGGTTTTGATCCACCCATCATCATCTTTGTCAACCAGAAGAAGGGTTGCGACGTGTT
GGCCAAGTCTCTGGAGAAGATGGGGTACAACGCCTGTACACTGCATGGTGGCAAAGGCCAGGAG
CAGCGAGAATTCGCATTGTCCAACCTCAAGGCTGGAGCCAAGGATATTCTGGTGGCTACAGATG
TGGCTGGTCGTGGTATCGATATCCAAGACGTATCTATGGTTGTCAACTACGACATGGCCAAAAA
CATTGAAGATTACATTCACCGAATTGGCCGCACAGGAAGAGCAGGCAAGAGTGGTGTAGCCATC
ACCTTCCTCACCAAAGAGGACTCAGCCGTGTTCTATGAACTGAAGCAAGCCATCCTGGAGAGCC
CAGTGTCCTCTTGCCCTCCAGAGCTGGCAAACCACCCAGATGCCCAGCACAAGCCAGGCACCAT
CCTTACCAAGAAGCGCAGGGAAGAGACCATCTTTGCCTGACACAGCACCTGAGTGGATTTGAAG
CCATGCTCTGAAACTGGTGCCTGTCCTAAGCCCTCATGACCCCTCCAGGCTCTTGTCCTTGGCT
CATGGGTCTTAGGAAGCAGCCAGAGTCCCTGGTTTGGAGCCTGTGAGGTGGGCTCCAAGGGAAC
AGGAAGGGCTGTAGGAGGCAGGAGCAGCACGCTATGGGGCAGCTGCCTAGCACGATCTCCAGCC
TGAACAAACACCTGGTCACCTGGAGGGGACTTCCTCAGCACACCTGTGTGACTGTACAGCAGTA
GTTGCCCTGAGTGACCCAGGGGATCTGGCATCATGAGGATTGTGGACCTTGGACTCTGTCACTC
TGACAACTGGTTTCCCATTCGGAGTTTAAAGCAGGTTGAGCGCCCTTAGAACTGCGCAGCCCTG
TGCCACACAACCTCTGTGCCACGGGTGCTGTGCACTCTGGGCATCCCTCCTCTCCCCGCCCCTC
GGAGTTTAAGTCAGTAATTTGTTTTCTATTCTCTGAGAAGATAAGTTTGTATGTTCTGAGAATA
AATACATGAATATTAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001100263	(Get FASTA)	NCBI Sequence Viewer
	XP_006257405	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI69082	(Get FASTA)	NCBI Sequence Viewer
	EDL87045	(Get FASTA)	NCBI Sequence Viewer
	EDL87046	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000072026
	ENSRNOP00000072026.3
	ENSRNOP00000100075.1

RefSeq Acc Id:

NP_001100263 ⟸ NM_001106793

- UniProtKB:

G3V9M1 (UniProtKB/TrEMBL), A6KC96 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAGELADKKDRDASPKEERKRSRTPERDRDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRS
KSTERERRHKERERDKERDRSKKERERDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKGDE
DEHGDKRPKIQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQKMLEEERK
KRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGG
IKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYG
DLMEKRRTLEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGK
IPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPL
LVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGF
RLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKP
DTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQ
KVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREF
ALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLT
KEDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA

hide sequence

RefSeq Acc Id:	XP_006257405 ⟸ XM_006257343
- Peptide Label:	isoform X1
- UniProtKB:	G3V9M1 (UniProtKB/TrEMBL), A6KC96 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAGELADKKDRDASPKEERKRSRTPERDRDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRS KSTERERRHKERERDKERDRSKKERERDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKGDE DEHGDKRPKIQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQKMLEEERK KRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGG IKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYG DLMEKRRTLEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGK IPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPL LVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGF RLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKP DTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQ KVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREF ALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLT KEDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA hide sequence

Ensembl Acc Id:

ENSRNOP00000072026 ⟸ ENSRNOT00000089612

Ensembl Acc Id:

ENSRNOP00000100075 ⟸ ENSRNOT00000167371

Protein Domains

DEAD-box RNA helicase Q Helicase ATP-binding Helicase C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-G3V9M1-F1-model_v2	AlphaFold	G3V9M1	1-819	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695628

Promoter ID:

EPDNEW_R6153

Type:

initiation region

Name:

Ddx23_1

Description:

DEAD-box helicase 23

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	140,342,717 - 140,342,777	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308685	AgrOrtholog
BioCyc Gene	G2FUF-32123	BioCyc
Ensembl Genes	ENSRNOG00000060154	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000089612	ENTREZGENE
	ENSRNOT00000089612.3	UniProtKB/TrEMBL
	ENSRNOT00000167371.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	DEAD-like_helicase	UniProtKB/TrEMBL
	DNA/RNA_helicase_DEAD/DEAH_N	UniProtKB/TrEMBL
	Helicase_C	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	PRP28/DDX23-like_helical	UniProtKB/TrEMBL
	RNA-helicase_DEAD-box_CS	UniProtKB/TrEMBL
	RNA_helicase_DEAD_Q_motif	UniProtKB/TrEMBL
KEGG Report	rno:300208	UniProtKB/TrEMBL
NCBI Gene	300208	ENTREZGENE
PANTHER	ATP-DEPENDENT RNA HELICASE DBP3	UniProtKB/TrEMBL
Pfam	DDX23	UniProtKB/TrEMBL
	DEAD	UniProtKB/TrEMBL
	Helicase_C	UniProtKB/TrEMBL
PhenoGen	Ddx23	PhenoGen
PROSITE	DEAD_ATP_HELICASE	UniProtKB/TrEMBL
	HELICASE_ATP_BIND_1	UniProtKB/TrEMBL
	HELICASE_CTER	UniProtKB/TrEMBL
	Q_MOTIF	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000060154	RatGTEx
SMART	DEXDc	UniProtKB/TrEMBL
	HELICc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0ABK0LFH6_RAT	UniProtKB/TrEMBL
	A6KC96	ENTREZGENE, UniProtKB/TrEMBL
	B5DFJ3_RAT	UniProtKB/TrEMBL
	G3V9M1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-01-13	Ddx23	DEAD-box helicase 23	Ddx23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Ddx23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	Ddx23_predicted	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Ddx23_predicted	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - KEGG (archival)