Slc19a2 (solute carrier family 19 member 2) - Rat Genome Database

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Gene: Slc19a2 (solute carrier family 19 member 2) Rattus norvegicus
Analyze
Symbol: Slc19a2
Name: solute carrier family 19 member 2
RGD ID: 1308611
Description: Predicted to enable thiamine transmembrane transporter activity. Predicted to be involved in several processes, including pyridoxine transport; thiamine diphosphate biosynthetic process; and thiamine transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Biomarker of chronic kidney disease. Human ortholog(s) of this gene implicated in diabetes mellitus; megaloblastic anemia; and thiamine-responsive megaloblastic anemia syndrome. Orthologous to human SLC19A2 (solute carrier family 19 member 2); PARTICIPATES IN thiamine metabolic pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC289175; MGC124887; solute carrier family 19 (thiamine transporter), member 2; thiamine transporter 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81379,135,118 - 79,149,316 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1379,135,059 - 79,149,315 (+)EnsemblGRCr8
mRatBN7.21376,601,975 - 76,616,175 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1376,601,900 - 76,616,172 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1379,220,427 - 79,234,615 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01380,524,434 - 80,538,620 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01377,779,112 - 77,793,296 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01382,552,586 - 82,566,586 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1382,552,550 - 82,566,586 (+)Ensemblrn6Rnor6.0
Rnor_5.01387,436,626 - 87,450,479 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41380,017,780 - 80,031,777 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1376,335,951 - 76,350,141 (+)NCBICelera
RGSC_v3.11380,031,967 - 80,045,928 (+)NCBI
Cytogenetic Map13q23NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-hydroxyphenyl retinamide  (ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (EXP)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carmustine  (EXP)
chloroprene  (ISO)
choline  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (ISO)
dibenz[a,h]anthracene  (ISO)
Dibutyl phosphate  (ISO)
diclofenac  (ISO)
dieldrin  (EXP)
dimethyl sulfoxide  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
elesclomol  (ISO)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
furan  (EXP)
gentamycin  (EXP)
heptachlor  (EXP)
hydralazine  (ISO)
indometacin  (ISO)
inulin  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
melphalan  (ISO)
metformin  (EXP)
methidathion  (ISO)
methotrexate  (EXP)
mirex  (EXP)
N-acetyl-L-cysteine  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
nefazodone  (EXP)
nickel sulfate  (ISO)
nimesulide  (EXP)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
rac-lactic acid  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
thiamine(1+) chloride  (ISO)
thioacetamide  (EXP)
tioguanine  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
zearalenone  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Effect of chronic kidney disease on the expression of thiamin and folic acid transporters. Bukhari FJ, etal., Nephrol Dial Transplant. 2011 Jul;26(7):2137-44. doi: 10.1093/ndt/gfq675. Epub 2010 Dec 13.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Mutations in SLC19A2 cause thiamine-responsive megaloblastic anaemia associated with diabetes mellitus and deafness. Labay V, etal., Nat Genet. 1999 Jul;22(3):300-4.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:11481326   PMID:12477932   PMID:18762716   PMID:19879271   PMID:21836059  


Genomics

Comparative Map Data
Slc19a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81379,135,118 - 79,149,316 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1379,135,059 - 79,149,315 (+)EnsemblGRCr8
mRatBN7.21376,601,975 - 76,616,175 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1376,601,900 - 76,616,172 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1379,220,427 - 79,234,615 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01380,524,434 - 80,538,620 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01377,779,112 - 77,793,296 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01382,552,586 - 82,566,586 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1382,552,550 - 82,566,586 (+)Ensemblrn6Rnor6.0
Rnor_5.01387,436,626 - 87,450,479 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41380,017,780 - 80,031,777 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1376,335,951 - 76,350,141 (+)NCBICelera
RGSC_v3.11380,031,967 - 80,045,928 (+)NCBI
Cytogenetic Map13q23NCBI
SLC19A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381169,463,909 - 169,485,970 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1169,463,909 - 169,485,944 (-)Ensemblhg38GRCh38
GRCh371169,433,147 - 169,455,208 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361167,699,791 - 167,721,865 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341166,164,825 - 166,186,899NCBI
Celera1142,542,928 - 142,564,985 (-)NCBICelera
Cytogenetic Map1q24.2NCBI
HuRef1140,656,190 - 140,678,233 (-)NCBIHuRef
CHM1_11170,855,181 - 170,877,241 (-)NCBICHM1_1
T2T-CHM13v2.01168,819,254 - 168,841,316 (-)NCBIT2T-CHM13v2.0
Slc19a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391164,076,615 - 164,092,954 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1164,076,615 - 164,092,954 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381164,249,046 - 164,265,385 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1164,249,046 - 164,265,385 (+)Ensemblmm10GRCm38
MGSCv371166,179,186 - 166,195,500 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361166,085,730 - 166,102,044 (+)NCBIMGSCv36mm8
Celera1166,660,848 - 166,702,585 (+)NCBICelera
Cytogenetic Map1H2.2NCBI
cM Map171.56NCBI
Slc19a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554627,786,913 - 7,805,792 (+)Ensembl
ChiLan1.0NW_0049554627,786,920 - 7,804,828 (+)NCBIChiLan1.0ChiLan1.0
SLC19A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2180,283,266 - 80,305,302 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1179,951,685 - 79,973,705 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01144,946,248 - 144,968,736 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11148,668,687 - 148,690,713 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1148,668,687 - 148,690,713 (-)EnsemblpanPan2panpan1.1
SLC19A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1729,094,341 - 29,114,319 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl729,094,101 - 29,113,249 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha728,625,929 - 28,645,880 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0728,896,300 - 28,916,259 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl728,896,045 - 28,914,377 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1728,744,718 - 28,764,672 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0728,780,311 - 28,800,248 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0729,017,158 - 29,037,096 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Slc19a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934499,350,348 - 99,381,143 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648117,197,095 - 17,227,891 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648117,197,133 - 17,225,435 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC19A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl481,510,098 - 81,536,464 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1481,510,221 - 81,535,099 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2489,134,887 - 89,159,766 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC19A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12559,568,801 - 59,587,398 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2559,568,893 - 59,585,094 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605561,243,780 - 61,261,916 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc19a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248267,380,827 - 7,400,665 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248267,382,158 - 7,400,702 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Slc19a2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11043,476,513 - 43,490,647 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Slc19a2
93 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:258
Count of miRNA genes:160
Interacting mature miRNAs:204
Transcripts:ENSRNOT00000003817
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)1371610804109350286Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)137161080489333251Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)137161080489333251Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137298450699745408Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)137161080489333251Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1368983334109350286Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)136242459288113509Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133483494779834947Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat

Markers in Region
RH131324  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21376,615,842 - 76,616,052 (+)MAPPERmRatBN7.2
Rnor_6.01382,566,256 - 82,566,465NCBIRnor6.0
Rnor_5.01387,450,149 - 87,450,358UniSTSRnor5.0
RGSC_v3.41380,031,447 - 80,031,656UniSTSRGSC3.4
Celera1376,349,811 - 76,350,020UniSTS
Cytogenetic Map13q22UniSTS
AU050020  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21376,601,570 - 76,601,688 (+)MAPPERmRatBN7.2
Rnor_6.01383,429,988 - 83,430,105NCBIRnor6.0
Rnor_5.01388,309,708 - 88,309,825UniSTSRnor5.0
RGSC_v3.41380,016,961 - 80,017,078UniSTSRGSC3.4
Celera1376,335,547 - 76,335,664UniSTS
Cytogenetic Map13q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000003817   ⟹   ENSRNOP00000003817
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1379,135,059 - 79,149,312 (+)Ensembl
mRatBN7.2 Ensembl1376,601,900 - 76,616,172 (+)Ensembl
Rnor_6.0 Ensembl1382,552,550 - 82,566,549 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076186
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1379,135,304 - 79,149,313 (+)Ensembl
mRatBN7.2 Ensembl1376,607,075 - 76,609,383 (+)Ensembl
Rnor_6.0 Ensembl1382,557,506 - 82,559,715 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076607   ⟹   ENSRNOP00000068194
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1379,135,275 - 79,149,315 (+)Ensembl
mRatBN7.2 Ensembl1376,602,132 - 76,616,172 (+)Ensembl
Rnor_6.0 Ensembl1382,552,586 - 82,566,586 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076722   ⟹   ENSRNOP00000068102
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1379,135,386 - 79,149,314 (+)Ensembl
mRatBN7.2 Ensembl1376,606,339 - 76,616,172 (+)Ensembl
Rnor_6.0 Ensembl1382,552,586 - 82,566,586 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076752
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1382,561,445 - 82,563,294 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119412   ⟹   ENSRNOP00000083604
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1379,135,066 - 79,149,313 (+)Ensembl
mRatBN7.2 Ensembl1376,601,975 - 76,616,172 (+)Ensembl
RefSeq Acc Id: NM_001030024   ⟹   NP_001025195
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81379,135,118 - 79,149,314 (+)NCBI
mRatBN7.21376,601,975 - 76,616,173 (+)NCBI
Rnor_6.01382,552,586 - 82,566,586 (+)NCBI
Rnor_5.01387,436,626 - 87,450,479 (+)NCBI
RGSC_v3.41380,017,780 - 80,031,777 (+)RGD
Celera1376,335,951 - 76,350,141 (+)RGD
Sequence:
RefSeq Acc Id: XM_039090492   ⟹   XP_038946420
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81379,135,341 - 79,149,316 (+)NCBI
mRatBN7.21376,602,201 - 76,616,175 (+)NCBI
RefSeq Acc Id: XM_039090493   ⟹   XP_038946421
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81379,135,341 - 79,149,316 (+)NCBI
mRatBN7.21376,602,201 - 76,616,175 (+)NCBI
RefSeq Acc Id: XM_039090494   ⟹   XP_038946422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81379,139,563 - 79,149,316 (+)NCBI
mRatBN7.21376,606,270 - 76,616,175 (+)NCBI
RefSeq Acc Id: XM_039090495   ⟹   XP_038946423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81379,139,563 - 79,149,316 (+)NCBI
mRatBN7.21376,606,270 - 76,616,175 (+)NCBI
RefSeq Acc Id: XM_039090496   ⟹   XP_038946424
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81379,140,379 - 79,149,316 (+)NCBI
mRatBN7.21376,607,236 - 76,616,175 (+)NCBI
RefSeq Acc Id: NP_001025195   ⟸   NM_001030024
- UniProtKB: Q499Q0 (UniProtKB/TrEMBL),   A0A8I5ZVN5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000068194   ⟸   ENSRNOT00000076607
Ensembl Acc Id: ENSRNOP00000003817   ⟸   ENSRNOT00000003817
Ensembl Acc Id: ENSRNOP00000068102   ⟸   ENSRNOT00000076722
RefSeq Acc Id: XP_038946420   ⟸   XM_039090492
- Peptide Label: isoform X1
- UniProtKB: A0A096MJE7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946421   ⟸   XM_039090493
- Peptide Label: isoform X2
- UniProtKB: F1LNC9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946422   ⟸   XM_039090494
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038946423   ⟸   XM_039090495
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038946424   ⟸   XM_039090496
- Peptide Label: isoform X5
Ensembl Acc Id: ENSRNOP00000083604   ⟸   ENSRNOT00000119412

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LNC9-F1-model_v2 AlphaFold F1LNC9 1-475 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308611 AgrOrtholog
BioCyc Gene G2FUF-17600 BioCyc
Ensembl Genes ENSRNOG00000002839 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003817 ENTREZGENE
  ENSRNOT00000003817.7 UniProtKB/TrEMBL
  ENSRNOT00000076186 ENTREZGENE
  ENSRNOT00000076186.3 UniProtKB/TrEMBL
  ENSRNOT00000076607.3 UniProtKB/TrEMBL
  ENSRNOT00000076722 ENTREZGENE
  ENSRNOT00000076722.4 UniProtKB/TrEMBL
  ENSRNOT00000119412 ENTREZGENE
  ENSRNOT00000119412.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7929969 IMAGE-MGC_LOAD
InterPro Folate_carrier UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/TrEMBL
  ThTr-1 UniProtKB/TrEMBL
KEGG Report rno:289175 UniProtKB/TrEMBL
MGC_CLONE MGC:124887 IMAGE-MGC_LOAD
NCBI Gene 289175 ENTREZGENE
PANTHER Folate_carrier UniProtKB/TrEMBL
  THIAMINE TRANSPORTER 1 UniProtKB/TrEMBL
Pfam Folate_carrier UniProtKB/TrEMBL
PhenoGen Slc19a2 PhenoGen
PIRSF Folate_carrier UniProtKB/TrEMBL
  Thiamine_transporter_1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002839 RatGTEx
Superfamily-SCOP MFS_gen_substrate_transporter UniProtKB/TrEMBL
UniProt A0A096MJE7 ENTREZGENE, UniProtKB/TrEMBL
  A0A096MJN0_RAT UniProtKB/TrEMBL
  A0A8I5Y7A5_RAT UniProtKB/TrEMBL
  A0A8I5ZVN5 ENTREZGENE, UniProtKB/TrEMBL
  F1LNC9 ENTREZGENE, UniProtKB/TrEMBL
  Q499Q0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-25 Slc19a2  solute carrier family 19 member 2  Slc19a2  solute carrier family 19 (thiamine transporter), member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Slc19a2  solute carrier family 19 (thiamine transporter), member 2  Slc19a2_predicted  solute carrier family 19 (thiamine transporter), member 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Slc19a2_predicted  solute carrier family 19 (thiamine transporter), member 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED