Ptpa (protein phosphatase 2 phosphatase activator) - Rat Genome Database

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Gene: Ptpa (protein phosphatase 2 phosphatase activator) Rattus norvegicus
Analyze
Symbol: Ptpa
Name: protein phosphatase 2 phosphatase activator
RGD ID: 1308354
Description: Predicted to enable several functions, including ATP binding activity; protein homodimerization activity; and protein phosphatase 2A binding activity. Predicted to contribute to phosphoprotein phosphatase activity. Predicted to be involved in mitotic spindle organization and positive regulation of apoptotic process. Predicted to be part of ATPase complex; calcium channel complex; and protein phosphatase type 2A complex. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in Parkinson's disease 25. Orthologous to human PTPA (protein phosphatase 2 phosphatase activator); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC362102; Ppp2r4; protein phosphatase 2 regulatory subunit 4; protein phosphatase 2A activator, regulatory subunit 4; protein phosphatase 2A regulatory subunit 4; protein phosphatase 2A, regulatory subunit B (PR 53); protein phosphatase 2a, regulatory subunit b' (pr 53); serine/threonine-protein phosphatase 2A activator
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8334,087,637 - 34,118,100 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl334,087,575 - 34,162,772 (+)EnsemblGRCr8
mRatBN7.2313,689,742 - 13,720,287 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl313,689,741 - 13,722,549 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx316,761,350 - 16,791,813 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0325,346,312 - 25,376,773 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0323,592,281 - 23,622,965 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.038,982,122 - 9,012,585 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl38,982,122 - 9,012,585 (+)Ensemblrn6Rnor6.0
Rnor_5.0314,334,896 - 14,365,358 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.439,461,718 - 9,492,181 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera38,456,362 - 8,486,834 (+)NCBICelera
RGSC_v3.139,472,909 - 9,491,620 (+)NCBI
Cytogenetic Map3p12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10318862   PMID:10830164   PMID:12477932   PMID:16916641   PMID:17333320   PMID:20568963   PMID:23376485   PMID:23533145  


Genomics

Comparative Map Data
Ptpa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8334,087,637 - 34,118,100 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl334,087,575 - 34,162,772 (+)EnsemblGRCr8
mRatBN7.2313,689,742 - 13,720,287 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl313,689,741 - 13,722,549 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx316,761,350 - 16,791,813 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0325,346,312 - 25,376,773 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0323,592,281 - 23,622,965 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.038,982,122 - 9,012,585 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl38,982,122 - 9,012,585 (+)Ensemblrn6Rnor6.0
Rnor_5.0314,334,896 - 14,365,358 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.439,461,718 - 9,492,181 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera38,456,362 - 8,486,834 (+)NCBICelera
RGSC_v3.139,472,909 - 9,491,620 (+)NCBI
Cytogenetic Map3p12NCBI
PTPA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389129,110,950 - 129,148,946 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9129,110,550 - 129,148,946 (+)Ensemblhg38GRCh38
GRCh379131,873,229 - 131,911,225 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369130,913,065 - 130,951,044 (+)NCBIBuild 36Build 36hg18NCBI36
Build 349128,953,166 - 128,990,777NCBI
Celera9102,525,511 - 102,563,513 (+)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9101,480,193 - 101,518,132 (+)NCBIHuRef
CHM1_19132,024,045 - 132,062,045 (+)NCBICHM1_1
T2T-CHM13v2.09141,314,397 - 141,352,390 (+)NCBIT2T-CHM13v2.0
Ptpa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39230,306,062 - 30,337,819 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl230,306,051 - 30,337,818 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38230,416,050 - 30,447,807 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl230,416,039 - 30,447,806 (+)Ensemblmm10GRCm38
MGSCv37230,271,570 - 30,303,327 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36230,238,059 - 30,269,813 (+)NCBIMGSCv36mm8
Celera230,120,848 - 30,152,502 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map221.71NCBI
Ptpa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555701,429,316 - 1,455,562 (+)Ensembl
ChiLan1.0NW_0049555701,429,316 - 1,454,820 (+)NCBIChiLan1.0ChiLan1.0
PTPA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21110,202,540 - 10,240,224 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1910,204,886 - 10,242,570 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09100,236,607 - 100,274,273 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19128,896,584 - 128,934,651 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9128,896,584 - 128,934,651 (+)EnsemblpanPan2panpan1.1
PTPA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1954,535,186 - 54,568,632 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl954,536,180 - 54,566,235 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha953,730,775 - 53,764,220 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0955,430,817 - 55,464,245 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl955,426,235 - 55,461,851 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1954,217,697 - 54,250,902 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0954,529,536 - 54,562,790 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0954,623,019 - 54,656,500 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ptpa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947196,768,400 - 196,795,560 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648716,542,888 - 16,564,646 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648716,536,740 - 16,564,087 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1269,401,514 - 269,431,462 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11269,401,776 - 269,431,465 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21303,417,989 - 303,447,667 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTPA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1129,017,533 - 9,056,856 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl129,019,024 - 9,056,703 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666096506,991 - 549,730 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptpa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247605,974,881 - 6,001,979 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247605,974,881 - 6,001,975 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ptpa
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v155,184,352 - 5,214,981 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ptpa
169 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:167
Count of miRNA genes:111
Interacting mature miRNAs:134
Transcripts:ENSRNOT00000024914
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32905627547904329Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10450811Scl73Serum cholesterol level QTL 734.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat
10450808Scl72Serum cholesterol level QTL 724.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
10450806Scl71Serum cholesterol level QTL 715.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)32862533967641995Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)3612543751125437Rat
8693641Alc30Alcohol consumption QTL 3020.739drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)33083238444921701Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3136721849Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3655634751556347Rat
1558657Cm43Cardiac mass QTL 436.63e-08heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31527234860272348Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)32905627547904329Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat

Markers in Region
D3Mco30  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2313,708,362 - 13,708,392 (+)MAPPERmRatBN7.2
mRatBN7.2313,708,362 - 13,708,597 (+)MAPPERmRatBN7.2
Rnor_6.039,000,661 - 9,000,895NCBIRnor6.0
Rnor_6.039,000,661 - 9,000,690NCBIRnor6.0
Rnor_5.0314,353,434 - 14,353,463UniSTSRnor5.0
Rnor_5.0314,353,434 - 14,353,668UniSTSRnor5.0
RGSC_v3.439,480,257 - 9,480,491UniSTSRGSC3.4
RGSC_v3.439,480,256 - 9,480,491RGDRGSC3.4
RGSC_v3.439,480,257 - 9,480,286UniSTSRGSC3.4
Celera38,474,910 - 8,475,144UniSTS
Celera38,474,910 - 8,474,939UniSTS
RGSC_v3.139,480,587 - 9,480,822RGD
Cytogenetic Map3p12UniSTS
RH127941  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2313,720,088 - 13,720,271 (+)MAPPERmRatBN7.2
Rnor_6.039,012,387 - 9,012,569NCBIRnor6.0
Rnor_5.0314,365,160 - 14,365,342UniSTSRnor5.0
RGSC_v3.439,491,983 - 9,492,165UniSTSRGSC3.4
Celera38,486,636 - 8,486,818UniSTS
RH 3.4 Map351.81UniSTS
Cytogenetic Map3p12UniSTS
RH125061  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2313,720,078 - 13,720,273 (+)MAPPERmRatBN7.2
Rnor_6.039,012,377 - 9,012,571NCBIRnor6.0
Rnor_5.0314,365,150 - 14,365,344UniSTSRnor5.0
RGSC_v3.439,491,973 - 9,492,167UniSTSRGSC3.4
Celera38,486,626 - 8,486,820UniSTS
Cytogenetic Map3p12UniSTS
REN36142  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2313,713,720 - 13,713,971 (+)MAPPERmRatBN7.2
Rnor_6.039,006,019 - 9,006,269NCBIRnor6.0
Rnor_5.0314,358,792 - 14,359,042UniSTSRnor5.0
RGSC_v3.439,485,615 - 9,485,865UniSTSRGSC3.4
Celera38,480,268 - 8,480,518UniSTS
Cytogenetic Map3p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000024914   ⟹   ENSRNOP00000024914
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl334,087,576 - 34,118,099 (+)Ensembl
mRatBN7.2 Ensembl313,689,742 - 13,720,271 (+)Ensembl
Rnor_6.0 Ensembl38,982,122 - 9,012,585 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107089   ⟹   ENSRNOP00000097647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl313,689,741 - 13,722,549 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108066   ⟹   ENSRNOP00000080286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl334,087,576 - 34,114,112 (+)Ensembl
mRatBN7.2 Ensembl313,689,741 - 13,717,299 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108795   ⟹   ENSRNOP00000080651
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl334,087,575 - 34,118,100 (+)Ensembl
mRatBN7.2 Ensembl313,689,742 - 13,720,271 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118909   ⟹   ENSRNOP00000097534
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl334,087,576 - 34,118,099 (+)Ensembl
mRatBN7.2 Ensembl313,689,742 - 13,720,271 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000124477   ⟹   ENSRNOP00000101729
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl334,087,576 - 34,127,296 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000128095   ⟹   ENSRNOP00000104822
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl334,087,576 - 34,118,099 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000135308   ⟹   ENSRNOP00000109918
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl334,087,576 - 34,136,585 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000151369   ⟹   ENSRNOP00000112595
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl334,087,576 - 34,162,772 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000156006   ⟹   ENSRNOP00000101565
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl334,087,576 - 34,141,945 (+)Ensembl
RefSeq Acc Id: NM_001108577   ⟹   NP_001102047
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8334,087,637 - 34,118,100 (+)NCBI
mRatBN7.2313,689,821 - 13,720,287 (+)NCBI
Rnor_6.038,982,122 - 9,012,585 (+)NCBI
Rnor_5.0314,334,896 - 14,365,358 (+)NCBI
RGSC_v3.439,461,718 - 9,492,181 (+)RGD
Celera38,456,362 - 8,486,834 (+)RGD
Sequence:
RefSeq Acc Id: XM_039105369   ⟹   XP_038961297
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8334,087,709 - 34,113,465 (+)NCBI
mRatBN7.2313,689,742 - 13,715,652 (+)NCBI
RefSeq Acc Id: NP_001102047   ⟸   NM_001108577
- UniProtKB: B2RYQ2 (UniProtKB/TrEMBL),   F7FF51 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024914   ⟸   ENSRNOT00000024914
RefSeq Acc Id: XP_038961297   ⟸   XM_039105369
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000080651   ⟸   ENSRNOT00000108795
Ensembl Acc Id: ENSRNOP00000097534   ⟸   ENSRNOT00000118909
Ensembl Acc Id: ENSRNOP00000097647   ⟸   ENSRNOT00000107089
Ensembl Acc Id: ENSRNOP00000080286   ⟸   ENSRNOT00000108066
Ensembl Acc Id: ENSRNOP00000101565   ⟸   ENSRNOT00000156006
Ensembl Acc Id: ENSRNOP00000112595   ⟸   ENSRNOT00000151369
Ensembl Acc Id: ENSRNOP00000109918   ⟸   ENSRNOT00000135308
Ensembl Acc Id: ENSRNOP00000104822   ⟸   ENSRNOT00000128095
Ensembl Acc Id: ENSRNOP00000101729   ⟸   ENSRNOT00000124477

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2RYQ2-F1-model_v2 AlphaFold B2RYQ2 1-323 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691960
Promoter ID:EPDNEW_R2485
Type:initiation region
Name:Ptpa_1
Description:protein phosphatase 2 phosphatase activator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.038,982,062 - 8,982,122EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308354 AgrOrtholog
BioCyc Gene G2FUF-50211 BioCyc
Ensembl Genes ENSRNOG00000018457 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024914.7 UniProtKB/TrEMBL
  ENSRNOT00000108066.2 UniProtKB/TrEMBL
  ENSRNOT00000108795.2 UniProtKB/TrEMBL
  ENSRNOT00000118909.2 UniProtKB/TrEMBL
  ENSRNOT00000124477.1 UniProtKB/TrEMBL
  ENSRNOT00000128095 ENTREZGENE
  ENSRNOT00000128095.1 UniProtKB/TrEMBL
  ENSRNOT00000135308 ENTREZGENE
  ENSRNOT00000135308.1 UniProtKB/TrEMBL
  ENSRNOT00000151369.1 UniProtKB/TrEMBL
  ENSRNOT00000156006.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.1150 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9101723 IMAGE-MGC_LOAD
InterPro Phstyr_phstse_ac UniProtKB/TrEMBL
  PTPA_C_lid UniProtKB/TrEMBL
  PTPA_sf UniProtKB/TrEMBL
KEGG Report rno:362102 UniProtKB/TrEMBL
MGC_CLONE MGC:188770 IMAGE-MGC_LOAD
NCBI Gene 362102 ENTREZGENE
PANTHER PTHR10012 UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR UniProtKB/TrEMBL
Pfam PTPA UniProtKB/TrEMBL
PhenoGen Ptpa PhenoGen
PIRSF Phstyr_phstse_ac UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018457 RatGTEx
Superfamily-SCOP SSF140984 UniProtKB/TrEMBL
UniProt A0A8I5ZPZ9_RAT UniProtKB/TrEMBL
  A0A8I5ZTH7_RAT UniProtKB/TrEMBL
  A0A8I6ASU9_RAT UniProtKB/TrEMBL
  A0ABK0L0P6_RAT UniProtKB/TrEMBL
  A0ABK0LHB2_RAT UniProtKB/TrEMBL
  A0ABK0LJ51_RAT UniProtKB/TrEMBL
  A0ABK0LZY4_RAT UniProtKB/TrEMBL
  A0ABK0M5C5_RAT UniProtKB/TrEMBL
  B2RYQ2 ENTREZGENE, UniProtKB/TrEMBL
  F7FF51 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-03 Ptpa  protein phosphatase 2 phosphatase activator  Ppp2r4  protein phosphatase 2 regulatory subunit 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-05-11 Ppp2r4  protein phosphatase 2 regulatory subunit 4  Ppp2r4  protein phosphatase 2A regulatory subunit 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-30 Ppp2r4  protein phosphatase 2A regulatory subunit 4  Ppp2r4  protein phosphatase 2A activator, regulatory subunit 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-12-15 Ppp2r4  protein phosphatase 2A activator, regulatory subunit 4  Ppp2r4  protein phosphatase 2A, regulatory subunit B (PR 53)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ppp2r4  protein phosphatase 2A, regulatory subunit B (PR 53)   Ppp2r4_predicted  protein phosphatase 2A, regulatory subunit B (PR 53) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ppp2r4_predicted  protein phosphatase 2A, regulatory subunit B' (PR 53) (predicted)      Symbol and Name status set to approved 70820 APPROVED