Rfesd (Rieske (Fe-S) domain containing) - Rat Genome Database

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Gene: Rfesd (Rieske (Fe-S) domain containing) Rattus norvegicus
Analyze
Symbol: Rfesd
Name: Rieske (Fe-S) domain containing
RGD ID: 1308284
Description: Predicted to enable 2 iron, 2 sulfur cluster binding activity. Orthologous to human RFESD (Rieske Fe-S domain containing); INTERACTS WITH (+)-schisandrin B; bisphenol A; gentamycin.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC361871; RGD1308284; Rieske domain-containing protein; similar to AI256775 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr827,220,389 - 7,254,394 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl27,237,947 - 7,247,628 (-)EnsemblGRCr8
mRatBN7.225,495,067 - 5,521,095 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl25,505,756 - 5,522,449 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx212,613,039 - 12,622,713 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0210,712,268 - 10,721,942 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.025,348,621 - 5,358,302 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.022,758,382 - 2,784,366 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl22,769,400 - 2,779,109 (-)Ensemblrn6Rnor6.0
Rnor_5.022,756,829 - 2,782,885 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.423,054,514 - 3,064,195 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera21,975,682 - 1,985,254 (-)NCBICelera
RGSC_v3.123,073,913 - 3,083,625 (-)NCBI
Cytogenetic Map2q11NCBI
JBrowse:




References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Rfesd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr827,220,389 - 7,254,394 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl27,237,947 - 7,247,628 (-)EnsemblGRCr8
mRatBN7.225,495,067 - 5,521,095 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl25,505,756 - 5,522,449 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx212,613,039 - 12,622,713 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0210,712,268 - 10,721,942 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.025,348,621 - 5,358,302 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.022,758,382 - 2,784,366 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl22,769,400 - 2,779,109 (-)Ensemblrn6Rnor6.0
Rnor_5.022,756,829 - 2,782,885 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.423,054,514 - 3,064,195 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera21,975,682 - 1,985,254 (-)NCBICelera
RGSC_v3.123,073,913 - 3,083,625 (-)NCBI
Cytogenetic Map2q11NCBI
RFESD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38595,646,777 - 95,658,082 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl595,646,718 - 95,684,773 (+)Ensemblhg38GRCh38
GRCh37594,982,481 - 94,993,786 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36595,008,340 - 95,018,600 (+)NCBIBuild 36Build 36hg18NCBI36
Celera590,860,909 - 90,871,275 (+)NCBICelera
Cytogenetic Map5q15NCBI
HuRef590,172,825 - 90,183,191 (+)NCBIHuRef
CHM1_1594,415,152 - 94,425,520 (+)NCBICHM1_1
T2T-CHM13v2.0596,147,700 - 96,159,005 (+)NCBIT2T-CHM13v2.0
Rfesd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391376,149,654 - 76,166,831 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1376,149,654 - 76,166,838 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381376,001,535 - 76,018,712 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1376,001,535 - 76,018,719 (-)Ensemblmm10GRCm38
MGSCv371376,138,983 - 76,156,160 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361376,467,537 - 76,484,564 (-)NCBIMGSCv36mm8
Celera1378,330,947 - 78,337,560 (-)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.95NCBI
Rfesd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541816,896,522 - 16,912,749 (-)Ensembl
ChiLan1.0NW_00495541816,897,714 - 16,900,324 (-)NCBIChiLan1.0ChiLan1.0
RFESD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2419,722,030 - 19,732,451 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1517,873,819 - 17,886,063 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0519,692,054 - 19,702,479 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1519,836,388 - 19,847,697 (-)NCBIPanPan1.1PanPan1.1panPan2
RFESD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1313,948,582 - 13,961,241 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl313,949,145 - 13,951,503 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha315,287,714 - 15,300,380 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0313,828,716 - 13,841,719 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl313,829,287 - 13,831,644 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1313,791,524 - 13,804,372 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0313,789,361 - 13,801,979 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0313,988,766 - 14,001,420 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rfesd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213169,493,816 - 169,506,043 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365237,678,444 - 7,691,453 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365237,679,232 - 7,691,447 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RFESD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2102,243,726 - 102,255,000 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.12102,243,788 - 102,254,278 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2295,686,349 - 95,696,840 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RFESD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1489,524,162 - 89,576,505 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl489,531,494 - 89,533,764 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604938,169,595 - 38,180,862 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rfesd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474314,296,683 - 14,309,507 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474314,295,923 - 14,322,805 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Rfesd
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13221,177,468 - 221,202,212 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rfesd
102 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:28
Count of miRNA genes:28
Interacting mature miRNAs:28
Transcripts:ENSRNOT00000017098
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)2573632550736325Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2142977529Rat
9590080Insglur4Insulin/glucose ratio QTL 428.70.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)2615276751152767Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat

Markers in Region
RH134887  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.225,506,105 - 5,506,288 (+)MAPPERmRatBN7.2
Rnor_6.022,769,421 - 2,769,603NCBIRnor6.0
Rnor_5.022,767,868 - 2,768,050UniSTSRnor5.0
RGSC_v3.423,054,535 - 3,054,717UniSTSRGSC3.4
Celera21,975,703 - 1,975,885UniSTS
Cytogenetic Map2q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000017098   ⟹   ENSRNOP00000017098
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl27,237,947 - 7,247,628 (-)Ensembl
mRatBN7.2 Ensembl25,505,756 - 5,522,449 (-)Ensembl
Rnor_6.0 Ensembl22,769,400 - 2,779,109 (-)Ensembl
RefSeq Acc Id: NM_001108540   ⟹   NP_001102010
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr827,237,947 - 7,247,628 (-)NCBI
mRatBN7.225,506,085 - 5,515,766 (-)NCBI
Rnor_6.022,769,400 - 2,779,109 (-)NCBI
Rnor_5.022,756,829 - 2,782,885 (-)NCBI
RGSC_v3.423,054,514 - 3,064,195 (-)RGD
Celera21,975,682 - 1,985,254 (-)RGD
Sequence:
RefSeq Acc Id: XM_006231706   ⟹   XP_006231768
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr827,233,025 - 7,252,900 (-)NCBI
mRatBN7.225,501,939 - 5,520,986 (-)NCBI
Rnor_6.022,769,358 - 2,784,363 (-)NCBI
Rnor_5.022,756,829 - 2,782,885 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006231708   ⟹   XP_006231770
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr827,233,025 - 7,252,839 (-)NCBI
mRatBN7.225,501,939 - 5,520,978 (-)NCBI
Rnor_6.022,769,358 - 2,784,363 (-)NCBI
Rnor_5.022,756,829 - 2,782,885 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006231709   ⟹   XP_006231771
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr827,233,025 - 7,252,865 (-)NCBI
mRatBN7.225,501,939 - 5,520,978 (-)NCBI
Rnor_6.022,769,358 - 2,784,363 (-)NCBI
Rnor_5.022,756,829 - 2,782,885 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039102503   ⟹   XP_038958431
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr827,233,025 - 7,252,841 (-)NCBI
mRatBN7.225,501,939 - 5,520,980 (-)NCBI
RefSeq Acc Id: XM_039102504   ⟹   XP_038958432
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr827,233,025 - 7,252,862 (-)NCBI
mRatBN7.225,501,939 - 5,520,978 (-)NCBI
RefSeq Acc Id: XM_039102505   ⟹   XP_038958433
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr827,233,025 - 7,254,394 (-)NCBI
mRatBN7.225,501,163 - 5,521,095 (-)NCBI
RefSeq Acc Id: XR_005500308
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr827,220,389 - 7,252,843 (-)NCBI
mRatBN7.225,495,067 - 5,515,755 (-)NCBI
RefSeq Acc Id: XR_005500309
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr827,220,389 - 7,252,843 (-)NCBI
mRatBN7.225,495,067 - 5,515,755 (-)NCBI
RefSeq Acc Id: NP_001102010   ⟸   NM_001108540
- UniProtKB: D3ZF58 (UniProtKB/TrEMBL),   A6I4F6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231771   ⟸   XM_006231709
- Peptide Label: isoform X2
- UniProtKB: D3ZF58 (UniProtKB/TrEMBL),   A6I4F6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231770   ⟸   XM_006231708
- Peptide Label: isoform X2
- UniProtKB: D3ZF58 (UniProtKB/TrEMBL),   A6I4F6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231768   ⟸   XM_006231706
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000017098   ⟸   ENSRNOT00000017098
RefSeq Acc Id: XP_038958433   ⟸   XM_039102505
- Peptide Label: isoform X2
- UniProtKB: D3ZF58 (UniProtKB/TrEMBL),   A6I4F6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958431   ⟸   XM_039102503
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038958432   ⟸   XM_039102504
- Peptide Label: isoform X2
- UniProtKB: D3ZF58 (UniProtKB/TrEMBL),   A6I4F6 (UniProtKB/TrEMBL)
Protein Domains
Rieske

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZF58-F1-model_v2 AlphaFold D3ZF58 1-154 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308284 AgrOrtholog
BioCyc Gene G2FUF-55085 BioCyc
Ensembl Genes ENSRNOG00000012810 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017098 ENTREZGENE
  ENSRNOT00000017098.7 UniProtKB/TrEMBL
Gene3D-CATH 2.102.10.10 UniProtKB/TrEMBL
InterPro Rieske_2Fe-2S UniProtKB/TrEMBL
  Rieske_2Fe-2S_sf UniProtKB/TrEMBL
  Sol_Rieske_ferrdox_dom UniProtKB/TrEMBL
KEGG Report rno:361871 UniProtKB/TrEMBL
NCBI Gene 361871 ENTREZGENE
PANTHER FERREDOXIN-RELATED UniProtKB/TrEMBL
  RIESKE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam Sol_Rieske_ferrdox UniProtKB/TrEMBL
PhenoGen Rfesd PhenoGen
PROSITE RIESKE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012810 RatGTEx
Superfamily-SCOP Rieske_dom UniProtKB/TrEMBL
UniProt A6I4F6 ENTREZGENE, UniProtKB/TrEMBL
  D3ZF58 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-26 Rfesd  Rieske (Fe-S) domain containing  RGD1308284_predicted  similar to AI256775 protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1308284_predicted  similar to AI256775 protein (predicted)  LOC361871_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC361871_predicted  similar to AI256775 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL