Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Lnx1 | Rat | 1,1-dichloroethene | decreases expression | ISO | Lnx1 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of LNX1 mRNA | CTD | PMID:26682919 | Lnx1 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Lnx1 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of LNX1 mRNA | CTD | PMID:22206623 | Lnx1 | Rat | 17beta-estradiol | decreases expression | ISO | LNX1 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of LNX1 mRNA | CTD | PMID:23019147|PMID:31614463 | Lnx1 | Rat | 17beta-estradiol | decreases expression | ISO | Lnx1 (Mus musculus) | 6480464 | Estradiol results in decreased expression of LNX1 mRNA | CTD | PMID:39298647 | Lnx1 | Rat | 17beta-estradiol | multiple interactions | ISO | LNX1 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of LNX1 mRNA | CTD | PMID:30165855 | Lnx1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of LNX1 mRNA | CTD | PMID:33387578 | Lnx1 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | LNX1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of LNX1 mRNA | CTD | PMID:30851411 | Lnx1 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Lnx1 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of LNX1 mRNA | CTD | PMID:39298647 | Lnx1 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of LNX1 mRNA | CTD | PMID:30047161 | Lnx1 | Rat | acrylamide | increases expression | ISO | Lnx1 (Mus musculus) | 6480464 | Acrylamide results in increased expression of LNX1 mRNA | CTD | PMID:30807115 | Lnx1 | Rat | afimoxifene | multiple interactions | ISO | LNX1 (Homo sapiens) | 6480464 | afimoxifene inhibits the reaction [Estrogens results in decreased expression of LNX1 mRNA] | CTD | PMID:21233418 | Lnx1 | Rat | aflatoxin B1 | decreases expression | ISO | LNX1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of LNX1 mRNA | CTD | PMID:27153756 | Lnx1 | Rat | aflatoxin B1 | increases methylation | ISO | LNX1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of LNX1 gene | CTD | PMID:27153756 | Lnx1 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of LNX1 mRNA | CTD | PMID:30047161 | Lnx1 | Rat | arsane | affects methylation | ISO | LNX1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of LNX1 gene | CTD | PMID:25304211 | Lnx1 | Rat | arsenic atom | affects methylation | ISO | LNX1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of LNX1 gene | CTD | PMID:25304211 | Lnx1 | Rat | arsenite(3-) | increases methylation | ISO | LNX1 (Homo sapiens) | 6480464 | arsenite results in increased methylation of LNX1 promoter | CTD | PMID:23974009 | Lnx1 | Rat | arsenite(3-) | multiple interactions | ISO | LNX1 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to LNX1 mRNA] | CTD | PMID:32406909 | Lnx1 | Rat | avobenzone | increases expression | ISO | LNX1 (Homo sapiens) | 6480464 | avobenzone results in increased expression of LNX1 mRNA | CTD | PMID:31016361 | Lnx1 | Rat | benzo[a]pyrene | affects methylation | ISO | LNX1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of LNX1 5' UTR; Benzo(a)pyrene affects the methylation of LNX1 promoter | CTD | PMID:27901495 | Lnx1 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Testosterone] results in increased expression of LNX1 mRNA | CTD | PMID:26496021 | Lnx1 | Rat | bisphenol A | decreases methylation | ISO | LNX1 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of LNX1 gene | CTD | PMID:31601247 | Lnx1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of LNX1 mRNA | CTD | PMID:25181051 | Lnx1 | Rat | cadmium dichloride | increases expression | ISO | Lnx1 (Mus musculus) | 6480464 | Cadmium Chloride results in increased expression of LNX1 mRNA | CTD | PMID:20061341 | Lnx1 | Rat | cadmium dichloride | increases expression | ISO | LNX1 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of LNX1 mRNA | CTD | PMID:38174414 | Lnx1 | Rat | cadmium dichloride | increases methylation | EXP | | 6480464 | Cadmium Chloride results in increased methylation of LNX1 promoter | CTD | PMID:22457795 | Lnx1 | Rat | carbon nanotube | decreases expression | ISO | Lnx1 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of LNX1 mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681 | Lnx1 | Rat | CGP 52608 | multiple interactions | ISO | LNX1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to LNX1 gene] | CTD | PMID:28238834 | Lnx1 | Rat | choline | multiple interactions | ISO | Lnx1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Lnx1 | Rat | crocidolite asbestos | decreases methylation | ISO | LNX1 (Homo sapiens) | 6480464 | Asbestos, Crocidolite results in decreased methylation of LNX1 5' UTR | CTD | PMID:29523930 | Lnx1 | Rat | dorsomorphin | multiple interactions | ISO | LNX1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Lnx1 | Rat | doxorubicin | decreases expression | ISO | LNX1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of LNX1 mRNA | CTD | PMID:29803840 | Lnx1 | Rat | entinostat | increases expression | ISO | LNX1 (Homo sapiens) | 6480464 | entinostat results in increased expression of LNX1 mRNA | CTD | PMID:26272509 | Lnx1 | Rat | entinostat | multiple interactions | ISO | LNX1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Lnx1 | Rat | epoxiconazole | decreases expression | ISO | Lnx1 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of LNX1 mRNA | CTD | PMID:35436446 | Lnx1 | Rat | fenofibrate | multiple interactions | ISO | Lnx1 (Mus musculus) | 6480464 | PPARA protein affects the reaction [Fenofibrate results in decreased expression of LNX1 mRNA] | CTD | PMID:21318169 | Lnx1 | Rat | fenofibrate | decreases expression | ISO | Lnx1 (Mus musculus) | 6480464 | Fenofibrate results in decreased expression of LNX1 mRNA | CTD | PMID:21318169 | Lnx1 | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of LNX1 mRNA | CTD | PMID:30307764 | Lnx1 | Rat | folic acid | multiple interactions | ISO | Lnx1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Lnx1 | Rat | fonofos | increases methylation | ISO | LNX1 (Homo sapiens) | 6480464 | Fonofos results in increased methylation of LNX1 promoter | CTD | PMID:22847954 | Lnx1 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of LNX1 mRNA | CTD | PMID:22061828 | Lnx1 | Rat | L-methionine | multiple interactions | ISO | Lnx1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Lnx1 | Rat | lead diacetate | multiple interactions | ISO | LNX1 (Homo sapiens) | 6480464 | [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of LNX1 mRNA | CTD | PMID:22839698 | Lnx1 | Rat | lead(0) | affects expression | ISO | LNX1 (Homo sapiens) | 6480464 | Lead affects the expression of LNX1 mRNA | CTD | PMID:28903495 | Lnx1 | Rat | Licochalcone B | decreases expression | ISO | LNX1 (Homo sapiens) | 6480464 | licochalcone B results in decreased expression of LNX1 mRNA | CTD | PMID:33647349 | Lnx1 | Rat | mercury dibromide | increases expression | ISO | LNX1 (Homo sapiens) | 6480464 | mercuric bromide results in increased expression of LNX1 mRNA | CTD | PMID:26272509 | Lnx1 | Rat | mercury dibromide | multiple interactions | ISO | LNX1 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Lnx1 | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of LNX1 mRNA | CTD | PMID:30047161 | Lnx1 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of LNX1 gene | CTD | PMID:35440735 | Lnx1 | Rat | methylmercury chloride | decreases expression | ISO | Lnx1 (Mus musculus) | 6480464 | methylmercuric chloride results in decreased expression of LNX1 mRNA | CTD | PMID:20061341 | Lnx1 | Rat | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | decreases expression | ISO | Lnx1 (Mus musculus) | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LNX1 mRNA | CTD | PMID:20061341 | Lnx1 | Rat | p-chloromercuribenzoic acid | increases expression | ISO | LNX1 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in increased expression of LNX1 mRNA | CTD | PMID:26272509 | Lnx1 | Rat | p-chloromercuribenzoic acid | multiple interactions | ISO | LNX1 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Lnx1 | Rat | panobinostat | multiple interactions | ISO | LNX1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Lnx1 | Rat | panobinostat | increases expression | ISO | LNX1 (Homo sapiens) | 6480464 | panobinostat results in increased expression of LNX1 mRNA | CTD | PMID:26272509 | Lnx1 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of LNX1 mRNA | CTD | PMID:33387578 | Lnx1 | Rat | parathion | increases methylation | ISO | LNX1 (Homo sapiens) | 6480464 | Parathion results in increased methylation of LNX1 promoter | CTD | PMID:22847954 | Lnx1 | Rat | phenylmercury acetate | increases expression | ISO | LNX1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of LNX1 mRNA | CTD | PMID:26272509 | Lnx1 | Rat | phenylmercury acetate | multiple interactions | ISO | LNX1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Lnx1 | Rat | pirinixic acid | increases expression | ISO | Lnx1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of LNX1 mRNA | CTD | PMID:20813756 | Lnx1 | Rat | pirinixic acid | multiple interactions | ISO | Lnx1 (Mus musculus) | 6480464 | PPARA protein affects the reaction [pirinixic acid results in decreased expression of LNX1 mRNA] | CTD | PMID:21318169 | Lnx1 | Rat | pirinixic acid | decreases expression | ISO | Lnx1 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of LNX1 mRNA | CTD | PMID:21318169 | Lnx1 | Rat | pirinixic acid | affects expression | ISO | Lnx1 (Mus musculus) | 6480464 | pirinixic acid affects the expression of LNX1 mRNA | CTD | PMID:17950772 | Lnx1 | Rat | rac-lactic acid | decreases expression | ISO | LNX1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of LNX1 mRNA | CTD | PMID:30851411 | Lnx1 | Rat | SB 431542 | multiple interactions | ISO | LNX1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Lnx1 | Rat | sodium arsenite | decreases expression | ISO | LNX1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of LNX1 mRNA | CTD | PMID:28595984 | Lnx1 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of LNX1 mRNA | CTD | PMID:19281266 | Lnx1 | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of LNX1 mRNA | CTD | PMID:30047161 | Lnx1 | Rat | sulforaphane | increases expression | ISO | Lnx1 (Mus musculus) | 6480464 | sulforaphane results in increased expression of LNX1 mRNA | CTD | PMID:30529165 | Lnx1 | Rat | terbufos | increases methylation | ISO | LNX1 (Homo sapiens) | 6480464 | terbufos results in increased methylation of LNX1 promoter | CTD | PMID:22847954 | Lnx1 | Rat | testosterone | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Testosterone] results in increased expression of LNX1 mRNA | CTD | PMID:26496021 | Lnx1 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of LNX1 mRNA | CTD | PMID:33387578 | Lnx1 | Rat | trichostatin A | increases expression | ISO | LNX1 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of LNX1 mRNA | CTD | PMID:24935251|PMID:26272509 | Lnx1 | Rat | trichostatin A | multiple interactions | ISO | LNX1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Lnx1 | Rat | triphenyl phosphate | affects expression | ISO | LNX1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of LNX1 mRNA | CTD | PMID:37042841 | Lnx1 | Rat | valproic acid | affects expression | ISO | Lnx1 (Mus musculus) | 6480464 | Valproic Acid affects the expression of LNX1 mRNA | CTD | PMID:17292431 | Lnx1 | Rat | valproic acid | multiple interactions | ISO | LNX1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Lnx1 | Rat | valproic acid | increases expression | ISO | LNX1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of LNX1 mRNA | CTD | PMID:23179753|PMID:24383497|PMID:24935251|PMID:26272509 | Lnx1 | Rat | zinc protoporphyrin | multiple interactions | ISO | LNX1 (Homo sapiens) | 6480464 | [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of LNX1 mRNA | CTD | PMID:22839698 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















