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Gene: Ap5m1 (adaptor related protein complex 5 subunit mu 1) Rattus norvegicus

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Symbol:

Ap5m1

Name:

adaptor related protein complex 5 subunit mu 1

RGD ID:

1308087

Description:

Predicted to be involved in endosomal transport. Predicted to be located in membrane. Predicted to be part of AP-type membrane coat adaptor complex. Predicted to be active in cytosol; late endosome; and lysosome. Orthologous to human AP5M1 (adaptor related protein complex 5 subunit mu 1); INTERACTS WITH bisphenol A; cocaine; ketamine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

adapter-related protein complex 5 mu subunit; adapter-related protein complex 5 subunit mu-1; adaptor-related protein complex 5 subunit mu-1; adaptor-related protein complex 5, mu 1 subunit; AP-5 complex subunit mu-1; LOC305861; MGC124703; MHD domain-containing death-inducing protein; mu-2-related death-inducing protein; MU-2/AP1M2 domain containing, death-inducing; Mu5; muD; Mudeng; RGD1308087; similar to RIKEN cDNA 4932432K03

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	24,835,122 - 24,864,854 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	24,835,100 - 24,862,606 (+)	Ensembl				GRCr8
mRatBN7.2	15	22,355,478 - 22,385,222 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	22,355,500 - 22,377,750 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	25,130,663 - 25,152,869 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	26,094,128 - 26,116,390 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	24,339,159 - 24,361,378 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	25,933,483 - 25,955,745 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	25,933,483 - 25,955,745 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	29,856,055 - 29,883,540 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	25,053,279 - 25,075,541 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	22,732,365 - 22,754,616 (+)	NCBI		Celera
RGSC_v3.1	15	25,069,198 - 25,089,945 (+)	NCBI
Cytogenetic Map	15	p14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

renal cell carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,4-methylenedioxymethamphetamine (ISO)

acrylamide (ISO)

antirheumatic drug (ISO)

atrazine (ISO)

belinostat (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

cocaine (EXP)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dibutyl phthalate (ISO)

dicrotophos (ISO)

dorsomorphin (ISO)

folic acid (ISO)

geldanamycin (ISO)

ketamine (EXP)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

paracetamol (ISO)

pirinixic acid (ISO)

progesterone (ISO)

quercetin (ISO)

quercetin 4'-O-beta-D-glucopyranoside (ISO)

SB 431542 (ISO)

silver atom (ISO)

silver(0) (ISO)

temozolomide (ISO)

thiram (ISO)

titanium dioxide (ISO)

topotecan (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

valproic acid (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endosomal transport (IBA,ISO,ISS)

protein transport (IEA)

Cellular Component

AP-type membrane coat adaptor complex (IBA,ISO,ISS)

cytosol (IBA,IEA,ISO,ISS)

late endosome (IBA,ISO,ISS)

late endosome membrane (IEA)

lysosomal membrane (IEA)

lysosome (IBA,ISO,ISS)

membrane (ISO,ISS)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:22022230

Genomics

Comparative Map Data

Ap5m1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	24,835,122 - 24,864,854 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	24,835,100 - 24,862,606 (+)	Ensembl				GRCr8
mRatBN7.2	15	22,355,478 - 22,385,222 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	22,355,500 - 22,377,750 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	25,130,663 - 25,152,869 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	26,094,128 - 26,116,390 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	24,339,159 - 24,361,378 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	25,933,483 - 25,955,745 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	25,933,483 - 25,955,745 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	29,856,055 - 29,883,540 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	25,053,279 - 25,075,541 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	22,732,365 - 22,754,616 (+)	NCBI		Celera
RGSC_v3.1	15	25,069,198 - 25,089,945 (+)	NCBI
Cytogenetic Map	15	p14	NCBI

AP5M1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	57,268,971 - 57,298,742 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	57,268,504 - 57,298,742 (+)	Ensembl			hg38	GRCh38
GRCh37	14	57,735,689 - 57,765,460 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	56,805,380 - 56,826,545 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	14	56,805,379 - 56,826,544	NCBI
Celera	14	37,785,692 - 37,806,883 (+)	NCBI		Celera
Cytogenetic Map	14	q22.3	NCBI
HuRef	14	37,900,404 - 37,921,545 (+)	NCBI		HuRef
CHM1_1	14	57,674,243 - 57,695,425 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	51,475,418 - 51,505,190 (+)	NCBI		T2T-CHM13v2.0

Ap5m1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	49,303,869 - 49,331,681 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	49,303,554 - 49,331,691 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	14	49,066,408 - 49,094,114 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	49,066,097 - 49,094,234 (+)	Ensembl			mm10	GRCm38
MGSCv37	14	49,686,170 - 49,707,398 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	14	47,988,500 - 48,009,674 (+)	NCBI		MGSCv36	mm8
Celera	14	45,267,199 - 45,288,655 (+)	NCBI		Celera
Cytogenetic Map	14	C1	NCBI
cM Map	14	25.36	NCBI

Ap5m1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955466	11,191,511 - 11,209,388 (+)	Ensembl
ChiLan1.0	NW_004955466	11,191,511 - 11,216,274 (+)	NCBI	ChiLan1.0	ChiLan1.0

AP5M1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	58,375,435 - 58,396,912 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	57,592,297 - 57,622,094 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	37,839,766 - 37,869,926 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	56,110,452 - 56,131,921 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	56,110,452 - 56,131,921 (+)	Ensembl			panPan2	panpan1.1

LOC100685159
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	79,914,436 - 79,982,053 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	32,848,205 - 32,902,815 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	79,620,787 - 79,622,854 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	80,582,419 - 80,584,487 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
UMICH_Zoey_3.1	4	80,256,587 - 80,258,655 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	80,376,999 - 80,379,067 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	80,940,052 - 80,942,120 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ap5m1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	72,274,015 - 72,329,014 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936495	1,862,747 - 1,881,766 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936495	1,862,790 - 1,900,955 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AP5M1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	186,430,227 - 186,461,319 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	186,430,154 - 186,464,347 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	207,004,493 - 207,027,562 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

AP5M1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	34,449,826 - 34,472,141 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	34,450,227 - 34,473,732 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666053	22,672,737 - 22,694,997 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ap5m1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624884	2,311,873 - 2,332,170 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624884	2,311,570 - 2,333,436 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ap5m1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	12	73,962,491 - 73,984,988 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ap5m1
151 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	663
Count of miRNA genes:	278
Interacting mature miRNAs:	340
Transcripts:	ENSRNOT00000018972
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1641913	Colcr2	Colorectal carcinoma resistance QTL 2	6.57	0.0197	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	15	2315759	47315759	Rat
61424	Scl1	Serum cholesterol level QTL 1	7.7	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	15	19155762	87086765	Rat
10401805	Kidm51	Kidney mass QTL 51			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	15	2785923	47785923	Rat
5684946	Bss98	Bone structure and strength QTL 98	3.9	0.0026	tibia strength trait (VT:1000284)	tibia ultimate force (CMO:0001734)	15	1	39411584	Rat
1354657	Despr13	Despair related QTL 13		0.0022	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	15	1	32342855	Rat
2317750	Glom26	Glomerulus QTL 26	4.3		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	15	14926594	71614418	Rat
1641887	Alcrsp14	Alcohol response QTL 14			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	15	1	44836456	Rat
631550	Bw7	Body weight QTL 7	3.6		body mass (VT:0001259)	body weight (CMO:0000012)	15	22336351	67336351	Rat
738017	Hcas7	Hepatocarcinoma susceptibility QTL 7	2.91		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	15	2315759	53331089	Rat
10755503	Bp391	Blood pressure QTL 391	2.37		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	15	22728353	42072050	Rat
5685002	Bss103	Bone structure and strength QTL 103	2.8		tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	15	16911521	32439851	Rat
2324620	Coatc3	Coat color QTL 3			coat/hair pigmentation trait (VT:0010463)	pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)	15	22336351	52597086	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001030036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093286	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093287	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005493717	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010057813	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC122613	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC099829	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474040	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000018972 ⟹ ENSRNOP00000018972

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	24,835,100 - 24,861,662 (+)	Ensembl
mRatBN7.2 Ensembl	15	22,355,543 - 22,377,750 (+)	Ensembl
Rnor_6.0 Ensembl	15	25,933,483 - 25,955,745 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096073 ⟹ ENSRNOP00000090061

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	24,835,100 - 24,862,606 (+)	Ensembl
mRatBN7.2 Ensembl	15	22,355,500 - 22,377,725 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000126250 ⟹ ENSRNOP00000106654

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	24,835,110 - 24,860,623 (+)	Ensembl

RefSeq Acc Id:

NM_001030036 ⟹ NP_001025207

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	24,835,122 - 24,857,384 (+)	NCBI
mRatBN7.2	15	22,355,487 - 22,377,751 (+)	NCBI
Rnor_6.0	15	25,933,483 - 25,955,745 (+)	NCBI
Rnor_5.0	15	29,856,055 - 29,883,540 (+)	NCBI
RGSC_v3.4	15	25,053,279 - 25,075,541 (+)	RGD
Celera	15	22,732,365 - 22,754,616 (+)	RGD

Sequence:

show sequence

TGAGATTCCGGGTGCAGGTTCTTAAGACCTTCTGAGGAGTGTTTTACCTTCCTGGAGGGACCAG
GAGACTTGAGTCACCTCACCCGGAAGAGCGAGCATCTCCAGTGAGCTCTTGCGGCGCCGGGAGA
ACCCCGACGTTGCGTGGTAGAGTCCTTTCAGAAGGCGGGGTCTACTCTGGCTGGATGGCGACCT
TAGTTTCTGTACTGCTCTGATACTTGAGTGGCTTAACCATGGCCCTGCGGGCAGTGTGGCTCAT
ACGTCACGAACCAGGAACTCCACTTGGTGGCACCGTCAAATTCTCCAGACGCTATCCTACTGTT
GAAAAGCGAGCGAAGGTCTTCAATGGAATGAATTATGTTCCTGTACCTGAAGACGGTCCCTTTC
TTAAAGCATTGCTCTTTCAACTTAGATTATTGGATGATGATAAGGACTTCGTGGAAAGCCGTGA
TAGCTGTTCAAACATCAATAAAACATCCATCTATGGGCTCTCAGTAGGAGGTGAAGATCTCTGG
CCAGTCATTGCTTTCCTGAGGAATGACATGATCTATGCAAGTGTTCCATTAGTTGAACAAGCTC
TGTCCCCTCGCCCACCTTTAATTAGTATTAGTGGGGTGTCACAAGGCTTGGAACTGCTTTTGGG
AGTACATGATTTTCTTTACTCCAGTCAGAAAAACGACACTGACCTCCACAGCAGACTGAGTCAG
TTGCCTGACTTGCTTCTGCAGGCTTGTCCTTTGGGGACTCTATTGGACGCTAACTTGCAGAACT
CACTGAATAGCCTTAACTTCGTATCTGTGACTCAGCCACAAAAACAGCCAGCCTGGAAAGTTGG
AACATACAAAGGAAAAGCACAGATTTCTATTTCTATCACTGAGAACGTAAAATCCATGCAATAT
GGTAAACAGGATATAGCAGACACATGGCAGGTCGTTGGGACAGTCGCTTGCAAGTGTGATTTGG
AGGGAGTCATGCCAAATGTCACCATCAGCTTGAATCTGCCCACCAATGGGTCTCCACTTCAAGA
CATTATTGTTCATCCTTGTGTGACTTCTCTGGATTCTGCCATCCTGACCTCCAGTAGCATTGAC
ACAGTAGATGACTCTGCTTTCAGTGGGCCATATAAATTTCCATTCACTCCACCCTTAGAGTCCT
TCAACTTATGCCACTACACTTCTCAGGTTCCTGTCCCACCAATACTGGGTTCTTACCACATGAA
AGAAGATGGAGCACAACTGAAAATAACAGTTAATTTAAAACTACACGAAAGTGTGCGGAATAAT
TTTGAAATCTGTGAAGCTCACATACCTTTTTACAACAGAGGTCCAATTACCCATTTGGAATACA
AAGTTAGTTTTGGTCAACTTGAGGTGTTTCGAGAAAAAAGCTTATTGGTCTGGATTATTGGCCA
GAAGTTCCCCAAATCAATGGAGATTAGCCTTTCAGGAACTCTAACTTTCAGAGTTCAGGGCCAT
AACAGGCAGCCGTTTGACCACATTTGTATTGGAAGCACAGCATATGTAAAGCTTAATTTTAGGA
TTGCAGATTATACACTCACCGGATGTTACGCAGATCAGCATTCGGTTCAAGTGTTTGCTTCAGG
AAAACCAAAAATAAGTGCATATCGGAAACTAATTTCTTCTGATTATTACATCTGGAATTCTAAA
GCATCTGCTCCAGTAACATATGCATCATTGTTACCATGACTTTTTTCATATTCAAAGGGATTTA
TATGATGGTAACATTCTGTAGTAGAATCATAGTATTTTAATTTTTTACATGCGTTCACACCACC
CATGACTGAAAAATTAGAGTGATTTCTTTATGAAAACATTCACATTTTATGTTTTCAGTCTGGT
GCAGTGTGAAAGAATATTTTCAAGGCTAACGTCTCCCTGGTTTTTGTTACCCTCTAATTTCAGG
CCACCACGACTCAGAATGTATAAAAGCAGTGGTTGGCTTTGGCCTAAGACTAGTCCTGAGTCTG
CCACGCACTCCTTCCTTTTCCATGGCAAGACAGTGCTTCAGTCAGAGCCCCTTCCTTGAGGAAG
AGCTCGGCCTTTCCTGGTGCAGGTTCAGGCAGCCATCCTATGGGCTGTAGTCGATTTACAAGGA
AAATGTGTGCTTACCCAAACCTCAGTACAGACAGTGCTGAATACCCATGGTCTGGTTAAGTAAT
CATAAACGGCTTCTTTCAAAGCATTTGGGAAAACGTTCAAATAGTAACCTGCTCTTCATCTCAT
CCCCTACCGGCCAATAGGCCTCCATAGTTCTGTTTTACGTTCTAGAGCTACTGTCTTTCTGAAA
TAGGCTCTCATGAAGCCTGGGCTGGCCTGGGCCTCACTGTGTAGCTCAGGATGATCCCTCTCAA
GTGCTGGGGTTACAGTGGTAAACCACCATGTCCAGTGCCCTTCTAGGGATCGAACTCAGGGCCT
CATGCTTGCCAGACCAGGACCCAAGAGCTGAGCCATGACTCCACTGCTCTAGGGCTGCCGTAAC
CAAGGCAGTAGGGTGACAGAACAGCTGTCCAGGATGCCAGTAGACCTAAGGCTGCCGCAATGAG
CCTCGTGATCTGTGATTACGTAGTGTCCCTGGACACTTTTAGATAATTGTTAAGTATTACAGTG
TTTGTTTGTTTGTTTGTTTGCTTAATTAAACTGTTAATGAATGAACTTAGGTAAACACCCAGAA
GCCTTCCTGTGGGTATCATTTAGACTTATTTAATATAGCACTTTTTTCTTTAAGTCTGTCCCCA
TCATTTCTTTTTATCATTTTCTTGATTCCTTAAAAACTGTCTTCCCATGCTCCTTATCCTCTCC
CATTTCCGCAATTCCACAACATATCTTTGTTCAAAGCAGCATGCTGTCCTCAAATTTGGCTTTA
AGTGACTATTTTAAAAAGTCTGAAGATCCCAGGAACTTAACTGATGCCAAATTTAGAAGCCTGA
CAAAAATATGAATTACAGAATAATATTTAATTAAACTTACTCGGGGTTCTGTTTCAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039093286 ⟹ XP_038949214

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	24,835,283 - 24,864,854 (+)	NCBI
mRatBN7.2	15	22,355,478 - 22,385,222 (+)	NCBI

RefSeq Acc Id:

XM_039093287 ⟹ XP_038949215

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	24,835,283 - 24,849,178 (+)	NCBI
mRatBN7.2	15	22,355,478 - 22,369,164 (+)	NCBI

RefSeq Acc Id:

XR_005493717

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	24,835,283 - 24,852,329 (+)	NCBI
mRatBN7.2	15	22,355,478 - 22,372,704 (+)	NCBI

RefSeq Acc Id:

XR_010057813

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	24,835,283 - 24,849,535 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001025207	(Get FASTA)	NCBI Sequence Viewer
	XP_038949214	(Get FASTA)	NCBI Sequence Viewer
	XP_038949215	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH99829	(Get FASTA)	NCBI Sequence Viewer
	EDL88389	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000090061
	ENSRNOP00000090061.1
	ENSRNOP00000106654
GenBank Protein	Q499N2	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001025207 ⟸ NM_001030036

- UniProtKB:

Q499N2 (UniProtKB/Swiss-Prot), A6KE84 (UniProtKB/TrEMBL), A0A8L2Q9R9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MALRAVWLIRHEPGTPLGGTVKFSRRYPTVEKRAKVFNGMNYVPVPEDGPFLKALLFQLRLLDD
DKDFVESRDSCSNINKTSIYGLSVGGEDLWPVIAFLRNDMIYASVPLVEQALSPRPPLISISGV
SQGLELLLGVHDFLYSSQKNDTDLHSRLSQLPDLLLQACPLGTLLDANLQNSLNSLNFVSVTQP
QKQPAWKVGTYKGKAQISISITENVKSMQYGKQDIADTWQVVGTVACKCDLEGVMPNVTISLNL
PTNGSPLQDIIVHPCVTSLDSAILTSSSIDTVDDSAFSGPYKFPFTPPLESFNLCHYTSQVPVP
PILGSYHMKEDGAQLKITVNLKLHESVRNNFEICEAHIPFYNRGPITHLEYKVSFGQLEVFREK
SLLVWIIGQKFPKSMEISLSGTLTFRVQGHNRQPFDHICIGSTAYVKLNFRIADYTLTGCYADQ
HSVQVFASGKPKISAYRKLISSDYYIWNSKASAPVTYASLLP

hide sequence

Ensembl Acc Id:

ENSRNOP00000018972 ⟸ ENSRNOT00000018972

RefSeq Acc Id:	XP_038949214 ⟸ XM_039093286
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2Q9R9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038949215 ⟸ XM_039093287
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000090061 ⟸ ENSRNOT00000096073

Ensembl Acc Id:

ENSRNOP00000106654 ⟸ ENSRNOT00000126250

Protein Domains

MHD

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q499N2-F1-model_v2	AlphaFold	Q499N2	1-490	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699618

Promoter ID:

EPDNEW_R10142

Type:

initiation region

Name:

Ap5m1_1

Description:

adaptor-related protein complex 5, mu 1 subunit

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	15	25,933,471 - 25,933,531	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308087	AgrOrtholog
BioCyc Gene	G2FUF-14110	BioCyc
Ensembl Genes	ENSRNOG00000014148	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000096073	ENTREZGENE
	ENSRNOT00000096073.1	UniProtKB/Swiss-Prot
	ENSRNOT00000126250	ENTREZGENE
Gene3D-CATH	Mu homology domain, subdomain B	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7933740	IMAGE-MGC_LOAD
InterPro	AP2_Mu_C_sf	UniProtKB/Swiss-Prot
	AP5M1	UniProtKB/Swiss-Prot
	MHD	UniProtKB/Swiss-Prot
KEGG Report	rno:305861	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:124703	IMAGE-MGC_LOAD
NCBI Gene	305861	ENTREZGENE
PANTHER	AP-5 COMPLEX SUBUNIT MU-1	UniProtKB/Swiss-Prot
	PTHR16082	UniProtKB/Swiss-Prot
Pfam	Adap_comp_sub	UniProtKB/Swiss-Prot
PhenoGen	Ap5m1	PhenoGen
PROSITE	MHD	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000014148	RatGTEx
Superfamily-SCOP	SSF49447	UniProtKB/Swiss-Prot
UniProt	A0A8L2Q9R9	ENTREZGENE, UniProtKB/TrEMBL
	A6KE84	ENTREZGENE, UniProtKB/TrEMBL
	AP5M1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-05-03	Ap5m1	adaptor related protein complex 5 subunit mu 1	Ap5m1	adaptor-related protein complex 5, mu 1 subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-10-05	Ap5m1	adaptor-related protein complex 5, mu 1 subunit	Mudeng	MU-2/AP1M2 domain containing, death-inducing	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2009-06-12	Mudeng	MU-2/AP1M2 domain containing, death-inducing	RGD1308087	similar to RIKEN cDNA 4932432K03	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1308087	similar to RIKEN cDNA 4932432K03	RGD1308087_predicted	similar to RIKEN cDNA 4932432K03 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1308087_predicted	similar to RIKEN cDNA 4932432K03 (predicted)	LOC305861_predicted		Symbol and Name status set to approved	1331353	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD