Ccm2 (CCM2 scaffold protein) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Ccm2 (CCM2 scaffold protein) Rattus norvegicus
Analyze
Symbol: Ccm2
Name: CCM2 scaffold protein
RGD ID: 1308067
Description: Predicted to be involved in heart development and vasculogenesis. Predicted to act upstream of or within several processes, including circulatory system development; endothelium development; and in utero embryonic development. Predicted to be located in cytoplasm. Predicted to be part of protein-containing complex. Human ortholog(s) of this gene implicated in cerebral cavernous malformation 2. Orthologous to human CCM2 (CCM2 scaffold protein); PARTICIPATES IN p38 MAPK signaling pathway; INTERACTS WITH 4,4'-sulfonyldiphenol; bisphenol A; bisphenol F.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CCM2 scaffolding protein; cerebral cavernous malformation 2; LOC305505; malcavernin
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81485,632,338 - 85,678,016 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1485,632,001 - 85,678,028 (+)EnsemblGRCr8
mRatBN7.21481,418,418 - 81,464,114 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1481,418,236 - 81,464,116 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1485,819,827 - 85,865,388 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01487,059,630 - 87,105,191 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01483,509,226 - 83,554,787 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,812,728 - 86,859,408 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,813,082 - 86,859,406 (+)Ensemblrn6Rnor6.0
Rnor_5.01480,446,382 - 80,492,853 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41487,307,223 - 87,353,553 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1480,300,228 - 80,345,851 (+)NCBICelera
RGSC_v3.11487,348,279 - 87,372,312 (+)NCBI
Cytogenetic Map14q21NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO)
mitochondrion  (IEA,ISO)
protein-containing complex  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mechanisms and functions of p38 MAPK signalling. Cuadrado A and Nebreda AR, Biochem J. 2010 Aug 1;429(3):403-17. doi: 10.1042/BJ20100323.
2. p38 MAP-kinases pathway regulation, function and role in human diseases. Cuenda A and Rousseau S, Biochim Biophys Acta. 2007 Aug;1773(8):1358-75. Epub 2007 Mar 24.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Deletions in CCM2 are a common cause of cerebral cavernous malformations. Liquori CL, etal., Am J Hum Genet. 2007 Jan;80(1):69-75. Epub 2006 Nov 14.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932   PMID:14740320   PMID:16037064   PMID:19151727   PMID:21795542  


Genomics

Comparative Map Data
Ccm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81485,632,338 - 85,678,016 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1485,632,001 - 85,678,028 (+)EnsemblGRCr8
mRatBN7.21481,418,418 - 81,464,114 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1481,418,236 - 81,464,116 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1485,819,827 - 85,865,388 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01487,059,630 - 87,105,191 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01483,509,226 - 83,554,787 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,812,728 - 86,859,408 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,813,082 - 86,859,406 (+)Ensemblrn6Rnor6.0
Rnor_5.01480,446,382 - 80,492,853 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41487,307,223 - 87,353,553 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1480,300,228 - 80,345,851 (+)NCBICelera
RGSC_v3.11487,348,279 - 87,372,312 (+)NCBI
Cytogenetic Map14q21NCBI
CCM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38744,999,746 - 45,076,470 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl744,999,475 - 45,076,469 (+)Ensemblhg38GRCh38
GRCh37745,039,345 - 45,116,069 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36745,006,312 - 45,082,594 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34744,813,091 - 44,889,290NCBI
Celera745,138,311 - 45,215,025 (+)NCBICelera
Cytogenetic Map7p13NCBI
HuRef744,925,168 - 45,000,206 (+)NCBIHuRef
CHM1_1745,071,187 - 45,120,010 (+)NCBICHM1_1
T2T-CHM13v2.0745,160,321 - 45,237,028 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2745,078,823 - 45,155,546 (+)NCBI
Ccm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39116,496,887 - 6,546,761 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl116,496,887 - 6,546,744 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38116,546,887 - 6,596,761 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl116,546,887 - 6,596,744 (+)Ensemblmm10GRCm38
MGSCv37116,446,890 - 6,496,764 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36116,446,959 - 6,496,747 (+)NCBIMGSCv36mm8
Celera117,046,830 - 7,080,913 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map114.45NCBI
Ccm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554567,227,667 - 7,256,206 (-)Ensembl
ChiLan1.0NW_0049554567,232,224 - 7,251,012 (-)NCBIChiLan1.0ChiLan1.0
CCM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2649,913,737 - 49,990,336 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1798,238,476 - 98,315,074 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0745,714,413 - 45,791,016 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1745,808,339 - 45,856,966 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl745,808,145 - 45,858,828 (+)EnsemblpanPan2panpan1.1
CCM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11610,347,801 - 10,392,560 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1610,347,145 - 10,394,594 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha162,564,197 - 2,608,955 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01614,251,951 - 14,296,712 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1614,251,983 - 14,273,877 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.01613,885,048 - 13,930,006 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01613,864,560 - 13,909,317 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ccm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118100,596,897 - 100,670,627 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647819,819,675 - 19,882,343 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647819,820,092 - 19,882,358 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1850,396,424 - 50,450,132 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11850,396,423 - 50,450,442 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21855,227,250 - 55,260,933 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12113,606,716 - 13,687,656 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2113,606,472 - 13,656,275 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660628,848,862 - 8,922,452 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247407,308,177 - 7,348,689 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247407,308,178 - 7,348,681 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ccm2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11175,478,250 - 75,527,783 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ccm2
222 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:72
Count of miRNA genes:58
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000010070
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1484164970100078267Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147297021087582095Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000088611   ⟹   ENSRNOP00000071026
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1485,647,617 - 85,678,013 (+)Ensembl
mRatBN7.2 Ensembl1481,418,236 - 81,464,116 (+)Ensembl
Rnor_6.0 Ensembl1486,828,355 - 86,859,220 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090360   ⟹   ENSRNOP00000071971
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1485,632,403 - 85,678,014 (+)Ensembl
mRatBN7.2 Ensembl1481,418,507 - 81,464,116 (+)Ensembl
Rnor_6.0 Ensembl1486,813,082 - 86,859,406 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097151   ⟹   ENSRNOP00000086895
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1485,632,001 - 85,678,014 (+)Ensembl
mRatBN7.2 Ensembl1481,441,049 - 81,463,714 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101757   ⟹   ENSRNOP00000081605
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1485,651,157 - 85,678,014 (+)Ensembl
mRatBN7.2 Ensembl1481,433,584 - 81,464,116 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102560   ⟹   ENSRNOP00000077225
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1481,440,752 - 81,464,116 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107154   ⟹   ENSRNOP00000091264
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1485,655,394 - 85,677,630 (+)Ensembl
mRatBN7.2 Ensembl1481,441,478 - 81,463,714 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118038   ⟹   ENSRNOP00000097841
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1485,647,735 - 85,678,028 (+)Ensembl
mRatBN7.2 Ensembl1481,433,819 - 81,464,116 (+)Ensembl
RefSeq Acc Id: NM_001126275   ⟹   NP_001119747
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,632,453 - 85,678,016 (+)NCBI
mRatBN7.21481,418,537 - 81,464,100 (+)NCBI
Rnor_6.01486,813,082 - 86,859,408 (+)NCBI
Rnor_5.01480,446,382 - 80,492,853 (+)NCBI
RGSC_v3.41487,307,223 - 87,353,553 (+)RGD
Celera1480,300,228 - 80,345,851 (+)RGD
Sequence:
RefSeq Acc Id: XM_006251318   ⟹   XP_006251380
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,646,912 - 85,678,016 (+)NCBI
mRatBN7.21481,433,715 - 81,464,114 (+)NCBI
Rnor_6.01486,826,508 - 86,859,408 (+)NCBI
Rnor_5.01480,446,382 - 80,492,853 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039092067   ⟹   XP_038947995
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,632,338 - 85,678,016 (+)NCBI
mRatBN7.21481,418,418 - 81,464,114 (+)NCBI
RefSeq Acc Id: NP_001119747   ⟸   NM_001126275
- UniProtKB: B1H273 (UniProtKB/TrEMBL),   F1LQ68 (UniProtKB/TrEMBL),   A0A0G2K1S9 (UniProtKB/TrEMBL),   A0A8I5Y9E2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251380   ⟸   XM_006251318
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JZF5 (UniProtKB/TrEMBL),   A0A8I5Y9E2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071971   ⟸   ENSRNOT00000090360
Ensembl Acc Id: ENSRNOP00000071026   ⟸   ENSRNOT00000088611
RefSeq Acc Id: XP_038947995   ⟸   XM_039092067
- Peptide Label: isoform X2
- UniProtKB: A0A8I6B6E1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000091264   ⟸   ENSRNOT00000107154
Ensembl Acc Id: ENSRNOP00000081605   ⟸   ENSRNOT00000101757
Ensembl Acc Id: ENSRNOP00000097841   ⟸   ENSRNOT00000118038
Ensembl Acc Id: ENSRNOP00000086895   ⟸   ENSRNOT00000097151
Ensembl Acc Id: ENSRNOP00000077225   ⟸   ENSRNOT00000102560
Protein Domains
Cerebral cavernous malformations 2 harmonin-   PID

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K1S9-F1-model_v2 AlphaFold A0A0G2K1S9 1-453 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699479
Promoter ID:EPDNEW_R10002
Type:initiation region
Name:Ccm2_1
Description:CCM2 scaffolding protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01486,813,047 - 86,813,107EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308067 AgrOrtholog
BioCyc Gene G2FUF-15073 BioCyc
Ensembl Genes ENSRNOG00000060825 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000088611 ENTREZGENE
  ENSRNOT00000088611.3 UniProtKB/TrEMBL
  ENSRNOT00000090360 ENTREZGENE
  ENSRNOT00000090360.3 UniProtKB/TrEMBL
  ENSRNOT00000097151.2 UniProtKB/TrEMBL
  ENSRNOT00000101757.2 UniProtKB/TrEMBL
  ENSRNOT00000107154.2 UniProtKB/TrEMBL
  ENSRNOT00000118038 ENTREZGENE
  ENSRNOT00000118038.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1160.20 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7441909 IMAGE-MGC_LOAD
InterPro CCM2_C UniProtKB/TrEMBL
  Malcavernin UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PTyr_interaction_dom UniProtKB/TrEMBL
KEGG Report rno:305505 UniProtKB/TrEMBL
MGC_CLONE MGC:188309 IMAGE-MGC_LOAD
NCBI Gene 305505 ENTREZGENE
PANTHER CEREBRAL CAVERNOUS MALFORMATIONS 2 PROTEIN UniProtKB/TrEMBL
  PTHR21642 UniProtKB/TrEMBL
Pfam CCM2_C UniProtKB/TrEMBL
PhenoGen Ccm2 PhenoGen
PROSITE PID UniProtKB/TrEMBL
RatGTEx ENSRNOG00000060825 RatGTEx
UniProt A0A0G2JZF5 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K1S9 ENTREZGENE
  A0A8I5Y9E2 ENTREZGENE
  A0A8I5ZT10_RAT UniProtKB/TrEMBL
  A0A8I6A682_RAT UniProtKB/TrEMBL
  A0A8I6B6E1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJG5_RAT UniProtKB/TrEMBL
  B1H273 ENTREZGENE, UniProtKB/TrEMBL
  F1LQ68 ENTREZGENE
UniProt Secondary A0A0G2K1S9 UniProtKB/TrEMBL
  F1LQ68 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-03-16 Ccm2  CCM2 scaffold protein  Ccm2  CCM2 scaffolding protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-11 Ccm2  CCM2 scaffolding protein  Ccm2  cerebral cavernous malformation 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ccm2  cerebral cavernous malformation 2   Ccm2_predicted  cerebral cavernous malformation 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ccm2_predicted  cerebral cavernous malformation 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED