Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Neurl4 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Neurl4 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NEURL4 mRNA | CTD | PMID:22206623 | Neurl4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NEURL4 mRNA | CTD | PMID:21215274 | Neurl4 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | NEURL4 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of NEURL4 mRNA | CTD | PMID:30851411 | Neurl4 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Neurl4 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of NEURL4 exon | CTD | PMID:33297965 | Neurl4 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Neurl4 (Mus musculus) | 6480464 | bisphenol S affects the methylation of NEURL4 gene | CTD | PMID:31683443 | Neurl4 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of NEURL4 mRNA | CTD | PMID:36041667 | Neurl4 | Rat | acrolein | multiple interactions | ISO | NEURL4 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of and results in increased oxidation of NEURL4 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of and results in increased oxidation of NEURL4 mRNA | CTD | PMID:32699268 | Neurl4 | Rat | acrylamide | decreases expression | ISO | NEURL4 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of NEURL4 mRNA | CTD | PMID:32763439 | Neurl4 | Rat | aflatoxin B1 | increases methylation | ISO | NEURL4 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of NEURL4 gene | CTD | PMID:27153756 | Neurl4 | Rat | alpha-pinene | multiple interactions | ISO | NEURL4 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of and results in increased oxidation of NEURL4 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of and results in increased oxidation of NEURL4 mRNA | CTD | PMID:32699268 | Neurl4 | Rat | aristolochic acid A | increases expression | ISO | NEURL4 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of NEURL4 mRNA | CTD | PMID:33212167 | Neurl4 | Rat | arsane | affects methylation | ISO | NEURL4 (Homo sapiens) | 6480464 | Arsenic affects the methylation of NEURL4 gene | CTD | PMID:25304211 | Neurl4 | Rat | arsenic atom | affects methylation | ISO | NEURL4 (Homo sapiens) | 6480464 | Arsenic affects the methylation of NEURL4 gene | CTD | PMID:25304211 | Neurl4 | Rat | benzo[a]pyrene | increases mutagenesis | ISO | NEURL4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased mutagenesis of NEURL4 gene | CTD | PMID:25435355 | Neurl4 | Rat | benzo[a]pyrene | increases methylation | ISO | NEURL4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of NEURL4 3' UTR | CTD | PMID:27901495 | Neurl4 | Rat | benzo[a]pyrene | increases expression | ISO | Neurl4 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of NEURL4 mRNA | CTD | PMID:22228805 | Neurl4 | Rat | benzo[a]pyrene | multiple interactions | ISO | Neurl4 (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of NEURL4 mRNA] | CTD | PMID:22228805 | Neurl4 | Rat | bisphenol A | decreases expression | ISO | NEURL4 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of NEURL4 mRNA | CTD | PMID:29275510 | Neurl4 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of NEURL4 mRNA | CTD | PMID:36041667 | Neurl4 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of NEURL4 mRNA | CTD | PMID:34947998 | Neurl4 | Rat | bisphenol A | multiple interactions | ISO | NEURL4 (Homo sapiens) | 6480464 | [[ginger extract results in increased abundance of Oils and Volatile] which co-treated with bisphenol A] affects the expression of NEURL4 protein | CTD | PMID:33376534 | Neurl4 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of NEURL4 mRNA | CTD | PMID:36041667 | Neurl4 | Rat | cadmium dichloride | increases methylation | EXP | | 6480464 | Cadmium Chloride results in increased methylation of NEURL4 promoter | CTD | PMID:22457795 | Neurl4 | Rat | cadmium dichloride | decreases expression | ISO | NEURL4 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of NEURL4 mRNA | CTD | PMID:38568856 | Neurl4 | Rat | cadmium dichloride | increases expression | ISO | NEURL4 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of NEURL4 protein | CTD | PMID:38185225 | Neurl4 | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of NEURL4 mRNA | CTD | PMID:33453195 | Neurl4 | Rat | carbon nanotube | decreases expression | ISO | Neurl4 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of NEURL4 mRNA | CTD | PMID:25554681 | Neurl4 | Rat | copper(II) sulfate | decreases expression | ISO | NEURL4 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of NEURL4 mRNA | CTD | PMID:19549813 | Neurl4 | Rat | coumarin | decreases phosphorylation | ISO | NEURL4 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of NEURL4 protein | CTD | PMID:35688186 | Neurl4 | Rat | dicrotophos | increases expression | ISO | NEURL4 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of NEURL4 mRNA | CTD | PMID:28302478 | Neurl4 | Rat | ethanol | affects splicing | ISO | Neurl4 (Mus musculus) | 6480464 | Ethanol affects the splicing of NEURL4 mRNA | CTD | PMID:30319688 | Neurl4 | Rat | folic acid | multiple interactions | ISO | Neurl4 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NEURL4 mRNA | CTD | PMID:22206623 | Neurl4 | Rat | folic acid | increases expression | ISO | Neurl4 (Mus musculus) | 6480464 | Folic Acid results in increased expression of NEURL4 mRNA | CTD | PMID:25629700 | Neurl4 | Rat | FR900359 | decreases phosphorylation | ISO | NEURL4 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of NEURL4 protein | CTD | PMID:37730182 | Neurl4 | Rat | lead diacetate | increases expression | ISO | Neurl4 (Mus musculus) | 6480464 | lead acetate results in increased expression of NEURL4 mRNA | CTD | PMID:20542052 | Neurl4 | Rat | ozone | multiple interactions | ISO | NEURL4 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of and results in increased oxidation of NEURL4 mRNA more ... | CTD | PMID:32699268 and PMID:35430440 | Neurl4 | Rat | rac-lactic acid | decreases expression | ISO | NEURL4 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of NEURL4 mRNA | CTD | PMID:30851411 | Neurl4 | Rat | titanium dioxide | decreases methylation | ISO | Neurl4 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of NEURL4 gene and titanium dioxide results in decreased methylation of NEURL4 promoter alternative form | CTD | PMID:35295148 | Neurl4 | Rat | titanium dioxide | decreases methylation | ISO | NEURL4 (Homo sapiens) | 6480464 | titanium dioxide results in decreased methylation of NEURL4 gene | CTD | PMID:34973136 | Neurl4 | Rat | titanium dioxide | increases expression | ISO | NEURL4 (Homo sapiens) | 6480464 | titanium dioxide results in increased expression of NEURL4 mRNA | CTD | PMID:34973136 | Neurl4 | Rat | valproic acid | increases methylation | ISO | NEURL4 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of NEURL4 gene | CTD | PMID:29154799 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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