Symbol:
Ints7
Name:
integrator complex subunit 7
RGD ID:
1308014
Description:
Predicted to be involved in DNA damage checkpoint signaling; RNA metabolic process; and cellular response to ionizing radiation. Predicted to be located in chromosome; cytoplasm; and nuclear body. Predicted to be part of INTAC complex and integrator complex. Predicted to be active in nucleus. Orthologous to human INTS7 (integrator complex subunit 7); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
LOC289382; RGD1308014; similar to DKFZP434B168 protein
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
INTS7 (integrator complex subunit 7)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Ints7 (integrator complex subunit 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Ints7 (integrator complex subunit 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
INTS7 (integrator complex subunit 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
INTS7 (integrator complex subunit 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Ints7 (integrator complex subunit 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
INTS7 (integrator complex subunit 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
INTS7 (integrator complex subunit 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Ints7 (integrator complex subunit 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Ints7 (integrator complex subunit 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
NCKAP5 (NCK associated protein 5)
HGNC
OMA
Alliance orthologs 3
Mus musculus (house mouse):
Ints7 (integrator complex subunit 7)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
INTS7 (integrator complex subunit 7)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
ints7 (integrator complex subunit 7)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
D1043.1
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|SonicParanoid)
Caenorhabditis elegans (roundworm):
D1043.1
Alliance
DIOPT (Ensembl Compara|InParanoid|OrthoFinder|OrthoInspector|PANTHER)
Drosophila melanogaster (fruit fly):
defl
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
ints7
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
ints7
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|PANTHER|PhylomeDB)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 13 105,686,208 - 105,739,609 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 13 105,686,128 - 105,739,608 (+) Ensembl GRCr8 mRatBN7.2 13 103,155,123 - 103,207,953 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 13 103,155,090 - 103,208,592 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 13 105,675,160 - 105,727,919 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 13 107,059,009 - 107,111,770 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 13 104,274,080 - 104,326,845 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Dahl_SR_JrHsd 13 105,057,215 - 105,109,964 (+) NCBI Dahl_SR_JrHsd Lyon_Normotensive 13 105,271,699 - 105,324,453 (+) NCBI Lyon_Normotensive Lyon_Hypertensive 13 105,212,696 - 105,265,453 (+) NCBI Lyon_Hypertensive F344_StmMcwi 13 105,267,782 - 105,320,541 (+) NCBI F344_StmMcwi Rnor_6.0 13 110,257,571 - 110,310,413 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 13 110,257,571 - 110,310,413 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 13 114,821,472 - 114,873,815 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 13 107,641,207 - 107,696,311 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 13 102,594,374 - 102,646,905 (+) NCBI Celera RGSC_v3.1 13 107,830,267 - 107,884,967 (+) NCBI Cytogenetic Map 13 q27 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Ints7 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Ints7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ints7 Rat 17beta-estradiol increases expression ISO INTS7 (Homo sapiens) 6480464 Estradiol results in increased expression of INTS7 mRNA CTD PMID:19167446 Ints7 Rat 17beta-estradiol multiple interactions ISO INTS7 (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of INTS7 mRNA CTD PMID:20823114 Ints7 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Ints7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ints7 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Ints7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ints7 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of INTS7 mRNA CTD PMID:22298810 Ints7 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO INTS7 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of INTS7 mRNA CTD PMID:22574217 Ints7 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ints7 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of INTS7 mRNA CTD PMID:21570461 Ints7 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Ints7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ints7 Rat 2-hydroxypropanoic acid decreases expression ISO INTS7 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of INTS7 mRNA CTD PMID:30851411 Ints7 Rat 4,4'-diaminodiphenylmethane increases expression ISO Ints7 (Mus musculus) 6480464 4,4'-diaminodiphenylmethane results in increased expression of INTS7 mRNA CTD PMID:18648102 Ints7 Rat 4,4'-sulfonyldiphenol decreases expression ISO Ints7 (Mus musculus) 6480464 bisphenol S results in decreased expression of INTS7 mRNA CTD PMID:39298647 Ints7 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of INTS7 mRNA CTD PMID:24780913|PMID:30047161 Ints7 Rat all-trans-retinoic acid decreases expression ISO INTS7 (Homo sapiens) 6480464 Tretinoin results in decreased expression of INTS7 mRNA CTD PMID:33167477 Ints7 Rat amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of INTS7 mRNA CTD PMID:38685447 Ints7 Rat amitrole increases expression EXP 6480464 Amitrole results in increased expression of INTS7 mRNA CTD PMID:30047161 Ints7 Rat antirheumatic drug increases expression ISO INTS7 (Homo sapiens) 6480464 Antirheumatic Agents results in increased expression of INTS7 mRNA CTD PMID:24449571 Ints7 Rat benzo[a]pyrene multiple interactions ISO Ints7 (Mus musculus) 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to INTS7 promoter] CTD PMID:19654925 Ints7 Rat benzo[a]pyrene diol epoxide I increases expression ISO INTS7 (Homo sapiens) 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of INTS7 mRNA CTD PMID:26238291 Ints7 Rat benzo[e]pyrene decreases methylation ISO INTS7 (Homo sapiens) 6480464 benzo(e)pyrene results in decreased methylation of INTS7 intron CTD PMID:30157460 Ints7 Rat bisphenol A decreases expression ISO Ints7 (Mus musculus) 6480464 bisphenol A results in decreased expression of INTS7 mRNA CTD PMID:26063408 Ints7 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of INTS7 mRNA CTD PMID:32145629|PMID:34947998 Ints7 Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of INTS7 mRNA CTD PMID:25181051 Ints7 Rat bucladesine multiple interactions ISO INTS7 (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of INTS7 mRNA CTD PMID:20823114 Ints7 Rat C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of INTS7 mRNA CTD PMID:19167457 Ints7 Rat cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of INTS7 more ... CTD PMID:39012411 Ints7 Rat cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of INTS7 more ... CTD PMID:39012411 Ints7 Rat caffeine decreases phosphorylation ISO INTS7 (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of INTS7 protein CTD PMID:35688186 Ints7 Rat carbon nanotube increases expression ISO Ints7 (Mus musculus) 6480464 Nanotubes, Carbon results in increased expression of INTS7 mRNA CTD PMID:25554681 Ints7 Rat chlorpyrifos decreases expression ISO Ints7 (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of INTS7 mRNA CTD PMID:37019170 Ints7 Rat coumestrol increases expression ISO INTS7 (Homo sapiens) 6480464 Coumestrol results in increased expression of INTS7 mRNA CTD PMID:19167446 Ints7 Rat coumestrol multiple interactions ISO INTS7 (Homo sapiens) 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of INTS7 mRNA CTD PMID:19167446 Ints7 Rat crocidolite asbestos decreases expression ISO Ints7 (Mus musculus) 6480464 Asbestos, Crocidolite results in decreased expression of INTS7 mRNA CTD PMID:29279043 Ints7 Rat cyclosporin A increases expression ISO INTS7 (Homo sapiens) 6480464 Cyclosporine results in increased expression of INTS7 mRNA CTD PMID:25562108 Ints7 Rat diethyl maleate decreases expression ISO Ints7 (Mus musculus) 6480464 diethyl maleate results in decreased expression of INTS7 mRNA CTD PMID:25270620 Ints7 Rat dorsomorphin multiple interactions ISO INTS7 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Ints7 Rat doxorubicin decreases expression ISO INTS7 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of INTS7 mRNA CTD PMID:29803840 Ints7 Rat epoxiconazole decreases expression ISO Ints7 (Mus musculus) 6480464 epoxiconazole results in decreased expression of INTS7 mRNA CTD PMID:35436446 Ints7 Rat ethanol affects expression ISO Ints7 (Mus musculus) 6480464 Ethanol affects the expression of INTS7 mRNA CTD PMID:30319688 Ints7 Rat fenvalerate increases expression EXP 6480464 fenvalerate results in increased expression of INTS7 mRNA CTD PMID:30307764 Ints7 Rat folic acid decreases expression ISO Ints7 (Mus musculus) 6480464 Folic Acid results in decreased expression of INTS7 mRNA CTD PMID:25629700 Ints7 Rat formaldehyde decreases expression ISO INTS7 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of INTS7 mRNA CTD PMID:23649840 Ints7 Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of INTS7 mRNA CTD PMID:33387578 Ints7 Rat hypochlorous acid decreases expression ISO Ints7 (Mus musculus) 6480464 Hypochlorous Acid results in decreased expression of INTS7 mRNA CTD PMID:19376150 Ints7 Rat ivermectin decreases expression ISO INTS7 (Homo sapiens) 6480464 Ivermectin results in decreased expression of INTS7 protein CTD PMID:32959892 Ints7 Rat medroxyprogesterone acetate multiple interactions ISO INTS7 (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of INTS7 mRNA CTD PMID:20823114 Ints7 Rat methapyrilene decreases methylation ISO INTS7 (Homo sapiens) 6480464 Methapyrilene results in decreased methylation of INTS7 intron CTD PMID:30157460 Ints7 Rat methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of INTS7 mRNA CTD PMID:38685447 Ints7 Rat methimazole increases expression EXP 6480464 Methimazole results in increased expression of INTS7 mRNA CTD PMID:30047161 Ints7 Rat methylmercury chloride decreases expression ISO INTS7 (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of INTS7 mRNA CTD PMID:28001369 Ints7 Rat nickel atom decreases expression ISO INTS7 (Homo sapiens) 6480464 Nickel results in decreased expression of INTS7 mRNA CTD PMID:23195993 Ints7 Rat okadaic acid increases expression ISO INTS7 (Homo sapiens) 6480464 Okadaic Acid results in increased expression of INTS7 mRNA CTD PMID:38832940 Ints7 Rat oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of INTS7 mRNA CTD PMID:25729387 Ints7 Rat paracetamol increases expression ISO INTS7 (Homo sapiens) 6480464 Acetaminophen results in increased expression of INTS7 mRNA CTD PMID:22230336 Ints7 Rat paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of INTS7 mRNA CTD PMID:33387578 Ints7 Rat PCB138 multiple interactions ISO Ints7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ints7 Rat perfluorohexanesulfonic acid decreases expression ISO INTS7 (Homo sapiens) 6480464 perfluorohexanesulfonic acid results in decreased expression of INTS7 mRNA CTD PMID:25812627 Ints7 Rat perfluorononanoic acid decreases expression ISO INTS7 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of INTS7 mRNA CTD PMID:25812627 Ints7 Rat perfluorooctane-1-sulfonic acid decreases expression ISO INTS7 (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in decreased expression of INTS7 mRNA CTD PMID:25812627 Ints7 Rat perfluorooctanoic acid decreases expression ISO INTS7 (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of INTS7 mRNA CTD PMID:25812627 Ints7 Rat rac-lactic acid decreases expression ISO INTS7 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of INTS7 mRNA CTD PMID:30851411 Ints7 Rat resveratrol multiple interactions ISO INTS7 (Homo sapiens) 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of INTS7 mRNA CTD PMID:19167446 Ints7 Rat resveratrol decreases expression ISO Ints7 (Mus musculus) 6480464 resveratrol results in decreased expression of INTS7 protein CTD PMID:25505154 Ints7 Rat SB 431542 multiple interactions ISO INTS7 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Ints7 Rat Soman increases expression EXP 6480464 Soman results in increased expression of INTS7 mRNA CTD PMID:19281266 Ints7 Rat sulfadimethoxine increases expression EXP 6480464 Sulfadimethoxine results in increased expression of INTS7 mRNA CTD PMID:30047161 Ints7 Rat tert-butyl hydroperoxide decreases methylation ISO INTS7 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in decreased methylation of INTS7 gene CTD PMID:29432895 Ints7 Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of INTS7 mRNA CTD PMID:23411599|PMID:34492290 Ints7 Rat titanium dioxide decreases methylation ISO Ints7 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of INTS7 gene CTD PMID:35295148 Ints7 Rat topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of INTS7 mRNA CTD PMID:25729387 Ints7 Rat trimellitic anhydride increases expression ISO Ints7 (Mus musculus) 6480464 trimellitic anhydride results in increased expression of INTS7 mRNA CTD PMID:19042947 Ints7 Rat triphenyl phosphate affects expression ISO INTS7 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of INTS7 mRNA CTD PMID:37042841 Ints7 Rat triptonide decreases expression ISO Ints7 (Mus musculus) 6480464 triptonide results in decreased expression of INTS7 mRNA CTD PMID:33045310 Ints7 Rat valproic acid decreases methylation ISO INTS7 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of INTS7 gene CTD PMID:29154799 Ints7 Rat valproic acid affects expression ISO INTS7 (Homo sapiens) 6480464 Valproic Acid affects the expression of INTS7 mRNA CTD PMID:25979313 Ints7 Rat valproic acid multiple interactions ISO INTS7 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Ints7 Rat valproic acid decreases expression ISO INTS7 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of INTS7 mRNA CTD PMID:23179753|PMID:24935251|PMID:26272509|PMID:27188386|PMID:28001369 Ints7 Rat vorinostat decreases expression ISO INTS7 (Homo sapiens) 6480464 vorinostat results in decreased expression of INTS7 mRNA CTD PMID:27188386