Symbol:
Ints7
Name:
integrator complex subunit 7
RGD ID:
1308014
Description:
Predicted to be involved in DNA damage checkpoint signaling; RNA metabolic process; and cellular response to ionizing radiation. Predicted to be located in chromosome and cytoplasm. Predicted to be part of INTAC complex and integrator complex. Predicted to be active in nucleus. Orthologous to human INTS7 (integrator complex subunit 7); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
LOC289382; RGD1308014; similar to DKFZP434B168 protein
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
INTS7 (integrator complex subunit 7)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Ints7 (integrator complex subunit 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Ints7 (integrator complex subunit 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
INTS7 (integrator complex subunit 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
INTS7 (integrator complex subunit 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Ints7 (integrator complex subunit 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
INTS7 (integrator complex subunit 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
INTS7 (integrator complex subunit 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Ints7 (integrator complex subunit 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Ints7 (integrator complex subunit 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
NCKAP5 (NCK associated protein 5)
HGNC
OMA
Alliance orthologs 3
Mus musculus (house mouse):
Ints7 (integrator complex subunit 7)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
INTS7 (integrator complex subunit 7)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
ints7 (integrator complex subunit 7)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
D1043.1
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|SonicParanoid)
Caenorhabditis elegans (roundworm):
D1043.1
Alliance
DIOPT (Ensembl Compara|InParanoid|OrthoFinder|OrthoInspector|PANTHER)
Drosophila melanogaster (fruit fly):
defl
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
ints7
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
ints7
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|PANTHER|PhylomeDB)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 13 105,686,208 - 105,739,609 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 13 105,686,128 - 105,739,608 (+) Ensembl GRCr8 mRatBN7.2 13 103,155,123 - 103,207,953 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 13 103,155,090 - 103,208,592 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 13 105,675,160 - 105,727,919 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 13 107,059,009 - 107,111,770 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 13 104,274,080 - 104,326,845 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 13 110,257,571 - 110,310,413 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 13 110,257,571 - 110,310,413 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 13 114,821,472 - 114,873,815 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 13 107,641,207 - 107,696,311 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 13 102,594,374 - 102,646,905 (+) NCBI Celera RGSC_v3.1 13 107,830,267 - 107,884,967 (+) NCBI Cytogenetic Map 13 q27 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Ints7 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Ints7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ints7 Rat 17beta-estradiol increases expression ISO INTS7 (Homo sapiens) 6480464 Estradiol results in increased expression of INTS7 mRNA CTD PMID:19167446 Ints7 Rat 17beta-estradiol multiple interactions ISO INTS7 (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of INTS7 mRNA CTD PMID:20823114 Ints7 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Ints7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ints7 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Ints7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ints7 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of INTS7 mRNA CTD PMID:22298810 Ints7 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO INTS7 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of INTS7 mRNA CTD PMID:22574217 Ints7 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ints7 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of INTS7 mRNA CTD PMID:21570461 Ints7 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Ints7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ints7 Rat 2-hydroxypropanoic acid decreases expression ISO INTS7 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of INTS7 mRNA CTD PMID:30851411 Ints7 Rat 4,4'-diaminodiphenylmethane increases expression ISO Ints7 (Mus musculus) 6480464 4,4'-diaminodiphenylmethane results in increased expression of INTS7 mRNA CTD PMID:18648102 Ints7 Rat 4,4'-sulfonyldiphenol decreases expression ISO Ints7 (Mus musculus) 6480464 bisphenol S results in decreased expression of INTS7 mRNA CTD PMID:39298647 Ints7 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of INTS7 mRNA CTD PMID:24780913|PMID:30047161 Ints7 Rat all-trans-retinoic acid decreases expression ISO INTS7 (Homo sapiens) 6480464 Tretinoin results in decreased expression of INTS7 mRNA CTD PMID:33167477 Ints7 Rat amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of INTS7 mRNA CTD PMID:38685447 Ints7 Rat amitrole increases expression EXP 6480464 Amitrole results in increased expression of INTS7 mRNA CTD PMID:30047161 Ints7 Rat antirheumatic drug increases expression ISO INTS7 (Homo sapiens) 6480464 Antirheumatic Agents results in increased expression of INTS7 mRNA CTD PMID:24449571 Ints7 Rat benzo[a]pyrene multiple interactions ISO Ints7 (Mus musculus) 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to INTS7 promoter] CTD PMID:19654925 Ints7 Rat benzo[a]pyrene diol epoxide I increases expression ISO INTS7 (Homo sapiens) 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of INTS7 mRNA CTD PMID:26238291 Ints7 Rat benzo[e]pyrene decreases methylation ISO INTS7 (Homo sapiens) 6480464 benzo(e)pyrene results in decreased methylation of INTS7 intron CTD PMID:30157460 Ints7 Rat bisphenol A decreases expression ISO Ints7 (Mus musculus) 6480464 bisphenol A results in decreased expression of INTS7 mRNA CTD PMID:26063408 Ints7 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of INTS7 mRNA CTD PMID:32145629|PMID:34947998 Ints7 Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of INTS7 mRNA CTD PMID:25181051 Ints7 Rat bucladesine multiple interactions ISO INTS7 (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of INTS7 mRNA CTD PMID:20823114 Ints7 Rat C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of INTS7 mRNA CTD PMID:19167457 Ints7 Rat cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of INTS7 more ... CTD PMID:39012411 Ints7 Rat cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of INTS7 more ... CTD PMID:39012411 Ints7 Rat caffeine decreases phosphorylation ISO INTS7 (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of INTS7 protein CTD PMID:35688186 Ints7 Rat carbon nanotube increases expression ISO Ints7 (Mus musculus) 6480464 Nanotubes, Carbon results in increased expression of INTS7 mRNA CTD PMID:25554681 Ints7 Rat chlorpyrifos decreases expression ISO Ints7 (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of INTS7 mRNA CTD PMID:37019170 Ints7 Rat coumestrol increases expression ISO INTS7 (Homo sapiens) 6480464 Coumestrol results in increased expression of INTS7 mRNA CTD PMID:19167446 Ints7 Rat coumestrol multiple interactions ISO INTS7 (Homo sapiens) 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of INTS7 mRNA CTD PMID:19167446 Ints7 Rat crocidolite asbestos decreases expression ISO Ints7 (Mus musculus) 6480464 Asbestos, Crocidolite results in decreased expression of INTS7 mRNA CTD PMID:29279043 Ints7 Rat cyclosporin A increases expression ISO INTS7 (Homo sapiens) 6480464 Cyclosporine results in increased expression of INTS7 mRNA CTD PMID:25562108 Ints7 Rat diethyl maleate decreases expression ISO Ints7 (Mus musculus) 6480464 diethyl maleate results in decreased expression of INTS7 mRNA CTD PMID:25270620 Ints7 Rat dorsomorphin multiple interactions ISO INTS7 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Ints7 Rat doxorubicin decreases expression ISO INTS7 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of INTS7 mRNA CTD PMID:29803840 Ints7 Rat epoxiconazole decreases expression ISO Ints7 (Mus musculus) 6480464 epoxiconazole results in decreased expression of INTS7 mRNA CTD PMID:35436446 Ints7 Rat ethanol affects expression ISO Ints7 (Mus musculus) 6480464 Ethanol affects the expression of INTS7 mRNA CTD PMID:30319688 Ints7 Rat fenvalerate increases expression EXP 6480464 fenvalerate results in increased expression of INTS7 mRNA CTD PMID:30307764 Ints7 Rat folic acid decreases expression ISO Ints7 (Mus musculus) 6480464 Folic Acid results in decreased expression of INTS7 mRNA CTD PMID:25629700 Ints7 Rat formaldehyde decreases expression ISO INTS7 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of INTS7 mRNA CTD PMID:23649840 Ints7 Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of INTS7 mRNA CTD PMID:33387578 Ints7 Rat hypochlorous acid decreases expression ISO Ints7 (Mus musculus) 6480464 Hypochlorous Acid results in decreased expression of INTS7 mRNA CTD PMID:19376150 Ints7 Rat ivermectin decreases expression ISO INTS7 (Homo sapiens) 6480464 Ivermectin results in decreased expression of INTS7 protein CTD PMID:32959892 Ints7 Rat medroxyprogesterone acetate multiple interactions ISO INTS7 (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of INTS7 mRNA CTD PMID:20823114 Ints7 Rat methapyrilene decreases methylation ISO INTS7 (Homo sapiens) 6480464 Methapyrilene results in decreased methylation of INTS7 intron CTD PMID:30157460 Ints7 Rat methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of INTS7 mRNA CTD PMID:38685447 Ints7 Rat methimazole increases expression EXP 6480464 Methimazole results in increased expression of INTS7 mRNA CTD PMID:30047161 Ints7 Rat methylmercury chloride decreases expression ISO INTS7 (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of INTS7 mRNA CTD PMID:28001369 Ints7 Rat nickel atom decreases expression ISO INTS7 (Homo sapiens) 6480464 Nickel results in decreased expression of INTS7 mRNA CTD PMID:23195993 Ints7 Rat okadaic acid increases expression ISO INTS7 (Homo sapiens) 6480464 Okadaic Acid results in increased expression of INTS7 mRNA CTD PMID:38832940 Ints7 Rat oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of INTS7 mRNA CTD PMID:25729387 Ints7 Rat paracetamol increases expression ISO INTS7 (Homo sapiens) 6480464 Acetaminophen results in increased expression of INTS7 mRNA CTD PMID:22230336 Ints7 Rat paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of INTS7 mRNA CTD PMID:33387578 Ints7 Rat PCB138 multiple interactions ISO Ints7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ints7 Rat perfluorohexanesulfonic acid decreases expression ISO INTS7 (Homo sapiens) 6480464 perfluorohexanesulfonic acid results in decreased expression of INTS7 mRNA CTD PMID:25812627 Ints7 Rat perfluorononanoic acid decreases expression ISO INTS7 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of INTS7 mRNA CTD PMID:25812627 Ints7 Rat perfluorooctane-1-sulfonic acid decreases expression ISO INTS7 (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in decreased expression of INTS7 mRNA CTD PMID:25812627 Ints7 Rat perfluorooctanoic acid decreases expression ISO INTS7 (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of INTS7 mRNA CTD PMID:25812627 Ints7 Rat rac-lactic acid decreases expression ISO INTS7 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of INTS7 mRNA CTD PMID:30851411 Ints7 Rat resveratrol multiple interactions ISO INTS7 (Homo sapiens) 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of INTS7 mRNA CTD PMID:19167446 Ints7 Rat resveratrol decreases expression ISO Ints7 (Mus musculus) 6480464 resveratrol results in decreased expression of INTS7 protein CTD PMID:25505154 Ints7 Rat SB 431542 multiple interactions ISO INTS7 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Ints7 Rat Soman increases expression EXP 6480464 Soman results in increased expression of INTS7 mRNA CTD PMID:19281266 Ints7 Rat sulfadimethoxine increases expression EXP 6480464 Sulfadimethoxine results in increased expression of INTS7 mRNA CTD PMID:30047161 Ints7 Rat tert-butyl hydroperoxide decreases methylation ISO INTS7 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in decreased methylation of INTS7 gene CTD PMID:29432895 Ints7 Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of INTS7 mRNA CTD PMID:23411599|PMID:34492290 Ints7 Rat titanium dioxide decreases methylation ISO Ints7 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of INTS7 gene CTD PMID:35295148 Ints7 Rat topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of INTS7 mRNA CTD PMID:25729387 Ints7 Rat trimellitic anhydride increases expression ISO Ints7 (Mus musculus) 6480464 trimellitic anhydride results in increased expression of INTS7 mRNA CTD PMID:19042947 Ints7 Rat triphenyl phosphate affects expression ISO INTS7 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of INTS7 mRNA CTD PMID:37042841 Ints7 Rat triptonide decreases expression ISO Ints7 (Mus musculus) 6480464 triptonide results in decreased expression of INTS7 mRNA CTD PMID:33045310 Ints7 Rat valproic acid decreases methylation ISO INTS7 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of INTS7 gene CTD PMID:29154799 Ints7 Rat valproic acid affects expression ISO INTS7 (Homo sapiens) 6480464 Valproic Acid affects the expression of INTS7 mRNA CTD PMID:25979313 Ints7 Rat valproic acid multiple interactions ISO INTS7 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Ints7 Rat valproic acid decreases expression ISO INTS7 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of INTS7 mRNA CTD PMID:23179753|PMID:24935251|PMID:26272509|PMID:27188386|PMID:28001369 Ints7 Rat vorinostat decreases expression ISO INTS7 (Homo sapiens) 6480464 vorinostat results in decreased expression of INTS7 mRNA CTD PMID:27188386