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Gene: Urb2 (URB2 ribosome biogenesis homolog) Rattus norvegicus

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Symbol:

Urb2

Name:

URB2 ribosome biogenesis homolog

RGD ID:

1307980

Description:

Predicted to be involved in ribosome biogenesis. Predicted to be located in midbody. Predicted to be active in nucleolus. Orthologous to human URB2 (URB2 ribosome biogenesis homolog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC292087; RGD1307980; similar to mKIAA0133 protein; unhealthy ribosome biogenesis protein 2 homolog; URB2 ribosome biogenesis 2; URB2 ribosome biogenesis 2 homolog; URB2 ribosome biogenesis 2 homolog (S. cerevisiae)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	URB2 (URB2 ribosome biogenesis homolog)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Urb2 (URB2 ribosome biogenesis 2 homolog (S. cerevisiae))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Urb2 (URB2 ribosome biogenesis homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	URB2 (URB2 ribosome biogenesis homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	URB2 (URB2 ribosome biogenesis homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Urb2 (URB2 ribosome biogenesis homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	URB2 (URB2 ribosome biogenesis homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	URB2 (URB2 ribosome biogenesis homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Urb2 (URB2 ribosome biogenesis homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Urb2 (URB2 ribosome biogenesis homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Urb2 (URB2 ribosome biogenesis 2 homolog (S. cerevisiae))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	URB2 (URB2 ribosome biogenesis homolog)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	urb2 (URB2 ribosome biogenesis homolog)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	urb2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	68,908,466 - 68,934,058 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	19	68,908,590 - 68,934,057 (+)	Ensembl				GRCr8
mRatBN7.2	19	52,011,019 - 52,036,607 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	52,011,112 - 52,036,597 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	19	58,796,572 - 58,819,905 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	59,648,965 - 59,672,273 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	61,722,999 - 61,746,332 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	56,802,843 - 56,827,017 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	56,803,382 - 56,826,960 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	19	67,516,625 - 67,541,817 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	19	54,212,367 - 54,235,676 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	19	51,387,782 - 51,411,090 (+)	NCBI		Celera
RGSC_v3.1	19	54,217,247 - 54,239,326 (+)	NCBI
Cytogenetic Map	19	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

epilepsy (ISO)

prostate cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(-)-alpha-phellandrene (ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,4'-trichlorobiphenyl (ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-phellandrene (ISO)

antirheumatic drug (ISO)

atrazine (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dimethyl sulfoxide (ISO)

dioxygen (ISO)

ethyl methanesulfonate (ISO)

formaldehyde (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

methyl methanesulfonate (ISO)

nickel atom (ISO)

paracetamol (EXP)

PCB138 (ISO)

perfluorononanoic acid (ISO)

pirinixic acid (ISO)

potassium dichromate (ISO)

quercetin (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

thiram (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

urethane (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ribosome biogenesis (IBA)

Cellular Component

midbody (IEA,ISO)

nucleolus (IBA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:19799413

Genomics

Comparative Map Data

Urb2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	68,908,466 - 68,934,058 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	19	68,908,590 - 68,934,057 (+)	Ensembl				GRCr8
mRatBN7.2	19	52,011,019 - 52,036,607 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	52,011,112 - 52,036,597 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	19	58,796,572 - 58,819,905 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	59,648,965 - 59,672,273 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	61,722,999 - 61,746,332 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	56,802,843 - 56,827,017 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	56,803,382 - 56,826,960 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	19	67,516,625 - 67,541,817 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	19	54,212,367 - 54,235,676 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	19	51,387,782 - 51,411,090 (+)	NCBI		Celera
RGSC_v3.1	19	54,217,247 - 54,239,326 (+)	NCBI
Cytogenetic Map	19	q12	NCBI

URB2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	229,626,247 - 229,660,200 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	229,625,855 - 229,660,887 (+)	Ensembl			hg38	GRCh38
GRCh37	1	229,761,994 - 229,795,947 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	227,828,604 - 227,862,569 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	226,068,715 - 226,102,681	NCBI
Celera	1	203,029,860 - 203,063,824 (+)	NCBI		Celera
Cytogenetic Map	1	q42.13	NCBI
HuRef	1	200,252,200 - 200,286,198 (+)	NCBI		HuRef
CHM1_1	1	231,034,292 - 231,068,275 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	229,005,197 - 229,039,181 (+)	NCBI		T2T-CHM13v2.0

Urb2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	124,748,236 - 124,775,244 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	124,748,247 - 124,775,244 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	8	124,021,497 - 124,048,505 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	124,021,508 - 124,048,505 (+)	Ensembl			mm10	GRCm38
MGSCv37	8	126,547,373 - 126,572,404 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	8	126,909,563 - 126,934,594 (+)	NCBI		MGSCv36	mm8
Celera	8	128,304,194 - 128,330,714 (+)	NCBI		Celera
Cytogenetic Map	8	E2	NCBI
cM Map	8	72.33	NCBI

Urb2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955492	8,451,048 - 8,478,728 (-)	Ensembl
ChiLan1.0	NW_004955492	8,451,367 - 8,478,213 (-)	NCBI	ChiLan1.0	ChiLan1.0

URB2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	19,550,586 - 19,585,859 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	19,744,201 - 19,778,132 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	205,170,805 - 205,204,644 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	210,202,498 - 210,234,815 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	210,202,498 - 210,234,815 (+)	Ensembl			panPan2	panpan1.1

URB2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	9,617,824 - 9,645,763 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	9,616,020 - 9,645,835 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	9,608,994 - 9,636,917 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	9,648,363 - 9,676,329 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	9,648,379 - 9,676,430 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	9,651,782 - 9,679,703 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	9,766,644 - 9,794,546 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	10,018,697 - 10,046,621 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Urb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	43,928,113 - 43,954,446 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936484	20,098,208 - 20,118,823 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936484	20,098,210 - 20,118,808 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

URB2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	60,229,112 - 60,254,974 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	60,229,026 - 60,254,462 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	65,040,686 - 65,077,788 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

URB2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	66,893,033 - 66,926,921 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	66,893,112 - 66,929,487 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666055	68,753,682 - 68,788,595 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Urb2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624775	19,467,428 - 19,492,825 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624775	19,467,978 - 19,496,827 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Urb2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	17	43,565,911 - 43,591,412 (+)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	271
Count of miRNA genes:	156
Interacting mature miRNAs:	195
Transcripts:	ENSRNOT00000036042
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631840	Niddm38	Non-insulin dependent diabetes mellitus QTL 38	3.86		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	19	10329076	74246245	Rat
724546	Kidm3	Kidney mass QTL 3	3.1		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	19	46226778	74246245	Rat
7411549	Bw130	Body weight QTL 130	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	32365311	74246245	Rat
1331737	Uae29	Urinary albumin excretion QTL 29	5.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	36289	74246245	Rat
724518	Uae19	Urinary albumin excretion QTL 19	5.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	24093973	69093973	Rat
61423	Cia14	Collagen induced arthritis QTL 14	3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	19	10833618	74246245	Rat
2313395	Anxrr26	Anxiety related response QTL 26			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	19	44385134	74246245	Rat
1578764	Stresp19	Stress response QTL 19	3.6	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	19	32539615	74246245	Rat
5135224	Leukc1	Leukocyte quantity QTL 1			eosinophil quantity (VT:0002602)	blood eosinophil count (CMO:0000033)	19	61249161	74246245	Rat
1331788	Rf45	Renal function QTL 45	2.818		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	19	31777888	74246245	Rat
7247442	Uae39	Urinary albumin excretion QTL 39			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	2194317	74246245	Rat
1549835	Tcas7	Tongue tumor susceptibility QTL 7		0.001	tongue integrity trait (VT:0010553)	squamous cell carcinoma of the head and neck tumor number (CMO:0001876)	19	41722546	74246245	Rat
724566	Uae12	Urinary albumin excretion QTL 12	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	2194317	74246245	Rat

Markers in Region

RH137246

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	19	52,036,289 - 52,036,439 (+)	MAPPER	mRatBN7.2
Rnor_6.0	19	56,826,700 - 56,826,849	NCBI	Rnor6.0
Rnor_5.0	19	67,541,500 - 67,541,649	UniSTS	Rnor5.0
RGSC_v3.4	19	54,235,359 - 54,235,508	UniSTS	RGSC3.4
Celera	19	51,410,773 - 51,410,922	UniSTS
RH 3.4 Map	19	727.7	UniSTS
Cytogenetic Map	19	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001135708	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097655	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001842206	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005496645	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC133405	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474054	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000036042 ⟹ ENSRNOP00000029895

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	19	68,908,590 - 68,934,057 (+)	Ensembl
mRatBN7.2 Ensembl	19	52,011,112 - 52,036,597 (+)	Ensembl
Rnor_6.0 Ensembl	19	56,803,382 - 56,826,960 (+)	Ensembl

RefSeq Acc Id:

NM_001135708 ⟹ NP_001129180

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	68,910,749 - 68,934,058 (+)	NCBI
mRatBN7.2	19	52,013,300 - 52,036,607 (+)	NCBI
Rnor_6.0	19	56,803,708 - 56,827,017 (+)	NCBI
Rnor_5.0	19	67,516,625 - 67,541,817 (+)	NCBI
RGSC_v3.4	19	54,212,367 - 54,235,676 (+)	RGD
Celera	19	51,387,782 - 51,411,090 (+)	RGD

Sequence:

show sequence

ATGGCTGCTGTTTATTCTGGTATTTCCTTTAAACTTAAAAGCAAGACAACTTCCTGGGAAGATA
AACTAAAATTAGCTCACTTTGCTTGGATTTCTCATCAGTGCTTTCTACCAAATAAAGAACAAGT
TTTACTTGATTGGGCAAGACAGTCATTGGTTGCATTTTATAAGAAGAAGCTTGAACTGCAGGAA
GATATTGTTGAAAGGCTCTGGGTCTATGTAGATAACATTCTACATAGCAGGAGATTACAGAATC
TCCTCAAGAATGGAAAGACTATAAATCTTCAGATTTCCCTTGTCAAGATCATAAATGAGAAAAT
CGAAGAGTTCTCACTTTCGGGATCCCAGAGGAGTATCTGCGCCATCCTGAGTTGCTGCCAGGGC
ATCCTCTCAGCACCTGCCCTTGCTGTCATCTACACAGCCAAACCAGAGCTTATTGTGGCTTTGC
TGAGCCAGCTCTGCTGGTCAGCCTGCAGACAACCAGAAGGAGCCATGACAGCCAAGCTATTTGA
GGTCATTCATCTGGCTCTTGACCATTACCTCAAACTTCAGCAGCAACAAGCCAACCCTAGGCGT
GTCTTTGGAGATATGACTGGCCACCTCTTCCAGCCCTGCCTAGTCCTGAGACACTTGCTTTTGG
GGGGCACATGGACACAGGCTAGTCAGGGTCAGCTATGGCAGGTACTGAGCCGAGATATCAGGAG
TAAGATTGATGCTGTTCTTCGAGGTGGCGTTTTTCGATATGATTTACTCTCATCCTATAAAGAG
GAGCTCCTGGAACAGCAACAAGAGAACGTAAAGATGGGAGTCCTGAAGAATCTCCTCACTCCGA
TGGACACTGTGATTACGAGACTGGTGGAGCCTGACTATGTCAAATCAGACCTGCATGCTTTGGT
TGTGGCCAGCTCAGTATCCTTGTTGTACAGACTCTTTCTGGACTCATACCTTAAGGAAGAAAAC
CAGTTTCTCTGCTTTCAGGTTCTCCCCAGGTTGTTTGGCTGCTTGCAAATTTCACACCTGCAGG
AGGGACAGATGGAAGCCCTGTCCCTCTCAGATTGGACCACAGAGCTTCTGGCTGTAGAGCAACT
ACTAAACTTAGTGGCCACCAGTAACATCTACAATGTAGCTGCTGACAGGATTCGGCATGGGGAG
ACACAGTTCCACTTCTACCGCCGTGTGGCTGAGCTGCTGATCAACCATTCACAAGCATCTGTGC
CAGCTTGGTTTCGCTGCCTCAAGATTCTGATGTCTCTAAATCATTTGATTTTAGAGCCAGACCT
GGATGACCTGTTGTCTTCGGCTTGGATAGATGCAGAAGTAACAGAATTTCGAGCCAAAAAAGCC
CAGGAGGTACTTATTAACACTGTCTTCCAGACGTATGCCAAGCTCCGACAGATGCCACAGTTGT
TTCAGGAGCTTTTAGAGGTGATCTGCCGTCCAGCTGCTGAGGCACTTCGACAGCCTTTGCTTGC
CTCAGGCCTCTCTATGGCTCTCTGTGCTTGTTTTTTGGAGCTGCCACTGAGTCAGATCCTGGAT
ACATGGTCCCTTGTACTGGATAAGTTCCAGTCTTTAGTCATGCCCTGTTTGCAGAGTGATACTG
ATATGGCTTTTAAGGCAATGTCACTTAGCTCTCTGCTACACTGCATCATGTTCAACATGCAGAG
TCTGGACAATAACATGCCTCTGCCCATCATCAGACGGACACAGTGCATGATGGAGAGGATGCTG
AGAGAGCTTGTGAAGCCCCTTTTGGGCCTTCTCCTGGACCTCTGGAGCCCAGAGCCTGAGCCGT
GGCAGCAGAAGGTGAGTGACTCTGCACTCTTACTCTCTTACACCTGGGCTCAGGTGGACACTAC
CCTGAGTTTGCACTGCAGCCAGTATTATTCTCTGGCAGTCTCCCTAGCCAGGGCTGCACTGGAC
AGCTCAAACCTCCCTTTGTTGCTACCAGGTGTGGAAACAGAGCTTTGGAAGAAGGTGGAAAAGT
GTATAGCCCAGTCCAGGTCTCTCAGTAGGTACTGCTTAGAACAGCTGTACCTTCAGAAGGTGAA
AAGGACTTTAATTCGGACTAGTTCCCAGTCCAAAGAAGCCCTTCAAACCTTGAGGTTTGACACT
GCCCACATTCTTGATTCTAGCAGAGACTGTTTAAGTCAGAAGACAGTAACTGCCTGGGATAGGC
AGGTGTCGACGATGAATGAGTCCTTGTATCCTGTAGCACACTGGCACTTGATTGTATCAAACCT
TACAGTTTTAATACCATATCTTTGTTTGAATGATGTGAGATATGTGGCCACTGTCTTGTTAAGA
ACTTTACCAACAAGTAAAGCCCAGGGAAGCTTGGCACCTGGTGAGTCATATGTCACACTTGAGA
AAATATCCACAGCCCTCCTTCACAGCCCTCTCTTTCCAGAGATGCAGTCCCTCTATTCTGCCTT
CCTGACTTGCATCATTGCAAAATGTTCTAACATTCTGTGCTCTGGTGCGCATAATGATCTGAGT
CTTAGTCAGCAGCTCCCCTGGCTTTTTGGAAAGGACTACCACACACTTGTGGCTCACTGGGAAA
CCAGATTGGCCAAAGTTGGATCTGAAGGTGTAGAACCAAGAGGAGAAATTGCCCAGAATTTTCT
ATCCATGGTCAAGAGTGGTTTTCCAATCAAGCTGCATGAAGATCAACTGAAAGACCTCCTGGAG
CTCTTCGATGTCATCTCTGCCCTCCACCTGGACAGCCTCTGGCCATCTTACCACGTGCATTTGT
TTTTCCTGCTGTTCTCCATGGCCGTCTCCACATTAGGGCATTGCTCTTGCCCCCTAGCCCTCCA
GTTCTTGGTGAAGTGCTACCAGCTCCTCAGTGGCCTGCAGAGAGGAAGGAACGCCCGCTCCGTA
TTCAGGGTCATGTACGTTAGTGACATCTTTGAGGTGGTGCTGACTTCACTGTTGCAAGCCAGTG
CAGAGTTTCAAGTTAGGGAGGATGACCCTGCTTGGCTGCAGCTTCTTCAAGTGTCAGGGGTGTT
CTTGGAACAGCTCATGCAAATGCTTATCCAAGCAAAGCTGAGCTTGGTGCTCAATTTTGGGAAA
ATCACTGCCTTTCTCTCCAAGTACAGTAAGGGAGCTTCCAGCAAAGAATTGAATATCCAGAACC
TTCGGAGCAGGCAACTGCTTCTGGTGGCTCTAACCAAATTGTGTCAAAGTTTGGGGCCTTGTGT
TAAGGAGCGGAGGCAGCTATTGGAGGCCCCAGCAGCACTCCCTGAGCTGCTGCAGCAGGCCATG
ATGCAGATGGGGGCCATGCTGCAGCTCTGCTTAGTGCCTGGGACTACAGGCTGCCGCCGCCGCC
TGCCTTCAGTTCTCCTCTCAGCTGTCCCTACACTTTTAGAAGTAGACCTGAGCCAGCACCTCAG
GGAAGGACAGCCCAAAATTGCTCAAGTGGTGGATACCGACAGAGCACTGCTTTCTCATGTGACA
CTTTACCAGGATGTCTACACTCAGTTGCTGGAGGAGTTGCCAGCCCTGTCGGGGAATACTCAGT
CTTTCCAGGCGGCGTTGCGATTTCTAACCTTGTTCCTTTTGGCCCCAGAGTTCCATTCCAAGGA
GAGCTCTGTTTTTGCTTCCATATTTTATTCTGTGCAGAAAGTTCTTACAGGTCCATGCATACCT
GCTCCAGTCACTCAGGATACTGAGCCTCATCTGGGAGCCCTGCTCACCCAAATGTTTAAGGCTG
AGACAACAGAGCACTTTGGGATGGTACTGCAGTCTATTCTTCAGGGGCTGGATGTCACTCAGGC
ATGGAGGTCGGATCTACAGGTTGTTTTGTGTGCCATTAGACTACTCAACCTGCTGCTCAAATGT
CCACTCAGTGGAGAAAAGGCGAGTTTGCTATGGCGTTCTTGCCCCCAGATAGTGACGGCTCTGA
TGCTGCAACACCGAGAGGCCTGCCAGGAGCAGCCTGTGGCCCTAGTAGTGGTTGAGCCTATTCT
TGAAGTGTTGGCTGTTCTGCTTCGGAAAGGGGAGGAGAGCATCAGCAACCCTCACCATGTCAAC
CTGGCCTTTAACATCTTGCTCACAGTCCCTCTTGAGCACCTGAAGCCACGGGAGTTTGGCAGTG
TCTTCCTGAAGACGCACAATGTGCTCTTCTCCATCTTGCAGTGCCACTCTAAGGTGATGCTGAA
GGCCATTCCGTCTTTCTTGAACTCCTTTAATAGACTGTTGCTTTCAGTGCTGCATGAAGGACGG
CAGAAAGACCAAGGGAGCATGGATGACCTGCCAGTGGTCCTTGAATGCGCACGCCTGGTGGAGA
GGATGTATAGCCACATTGCTACTCGAGCTGAGGAGTTCACCACGTTCTCCCCATTCCTGGTGGC
CCAGTATGTGACAGAGGTACAGAAGGTAACCTTGTACCCACCTGTGAAGAACCTACTTCAGGAA
GGAATTTATCTCATCTTGGATCTCTGCATGGAGCGGGATATCCAGTTTCTACGGGCTTCACTAC
AGTCTGGAGCCCGAGATGTCTTTAAGGACCTGCACAGTGACTACCTCAAGTACCACAAGGCCAA
GCATGAGGGAGAGAAGAGATATACGGCCTAGGCCACAGCACAGAAGCACCTGGGGCACCTTGCA
GAATATTCATGGTTCAGAGCCCTGGAGGATGTCAGGCTTCTGAAGTTCTCATGCATATTGTCAA
CAACCATAGGACACACACAGACACACACTCGCACTCACACACTCTCTCACTGTACATCCTTGAA
TGGCCTAGAGCTCACTATGTAGAACACCAGCGTGGCCTTGAACTCACAAAGATACCTGTGCTTT
CTGTATGCTGAGTCTAAATGCACAAACCACCTTGCCCACTTTGGAGATTTCATATTTTTATAGC
TTTTTTTAAAATGCTAAATGTTTTTTTGATATCCTGTCCCCAGCAGGATAAAGATTGAACACAG
CCCCCCCACACACACACACACACACACACACTAATCTCACACTGCTGCTGCTCAGTACACCTTT
TAAAACTAAGTGTGGTATAAGAGTCCTGGAAATCGGGACTGGGGCTGGTGGTATACACCTTTAA
TCTCAGCATTCAGGAGGCAGAAGGAGGTGGATCTCTGTGAGTTTGAGGCCAGCAAAGTCTAGGA
CAGCCACACAAAGAAACCCTATATCAAAAACCAAAAGAAAGAAAGAAACAAACTTGGATATAGG
TTCTGAGGTTAATTTAATGGAGAAATTGCTGACCATTATGACTGTACCTTGTGTGGTCCTTTCC
TTTTTTTCTCTCCTGGCTGGAAACTGTAGAACTGGTGTTTTGCTTCTGATACATGGGTCAATAA
TTAAATCCTGTTTGAATAACTCTTCTCTTTAAATTAAATCAGGCTGCAGAGAGACACTTTCCAG
CTGCCACCCTGTGCCTTCCCTTTGAGAATTCTGGTGGTGCTGGGGAAGAGCCATGGCCCTGCAT
AGGGTGGTGTGTAACTGTCTGGTAGGAGGTACTCTAGCACACGAGACAGGACTCCTGCTAGTTC
CCGCCTCAGTTTGAGAAATTGATTACAAATATTTTCCTACTCAGTTAAAAATAATGTTAAATGT
TCTTACTACCTAAACAATAATATTGTAATGGTCTCAATTATCAAGCCTTTATTATCACTTGGAA
ATGTCTTGTTTTAGAGTCTTTGTTATGTATATATAAATACATATGTATATATATATGTGTGTGT
ATACAGTAAATTGATCAAAAATGTGTTTTAAGGTTACTTAATTTTTTTATTGTAATAGTTGTCA
TTAACTTAAGAGTCAATAAAAATATTTGGTATTTTTTTAATGTTA

hide sequence

RefSeq Acc Id:

XM_039097655 ⟹ XP_038953583

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	68,908,609 - 68,934,058 (+)	NCBI
mRatBN7.2	19	52,011,106 - 52,036,607 (+)	NCBI

RefSeq Acc Id:

XM_063277955 ⟹ XP_063134025

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	68,908,466 - 68,934,058 (+)	NCBI

RefSeq Acc Id:

XR_005496645

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	68,908,609 - 68,927,720 (+)	NCBI
mRatBN7.2	19	52,011,149 - 52,030,268 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001129180	(Get FASTA)	NCBI Sequence Viewer
	XP_038953583	(Get FASTA)	NCBI Sequence Viewer
	XP_063134025	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL96723	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000029895
	ENSRNOP00000029895.6

RefSeq Acc Id:

NP_001129180 ⟸ NM_001135708

- UniProtKB:

D4AAN0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAVYSGISFKLKSKTTSWEDKLKLAHFAWISHQCFLPNKEQVLLDWARQSLVAFYKKKLELQE
DIVERLWVYVDNILHSRRLQNLLKNGKTINLQISLVKIINEKIEEFSLSGSQRSICAILSCCQG
ILSAPALAVIYTAKPELIVALLSQLCWSACRQPEGAMTAKLFEVIHLALDHYLKLQQQQANPRR
VFGDMTGHLFQPCLVLRHLLLGGTWTQASQGQLWQVLSRDIRSKIDAVLRGGVFRYDLLSSYKE
ELLEQQQENVKMGVLKNLLTPMDTVITRLVEPDYVKSDLHALVVASSVSLLYRLFLDSYLKEEN
QFLCFQVLPRLFGCLQISHLQEGQMEALSLSDWTTELLAVEQLLNLVATSNIYNVAADRIRHGE
TQFHFYRRVAELLINHSQASVPAWFRCLKILMSLNHLILEPDLDDLLSSAWIDAEVTEFRAKKA
QEVLINTVFQTYAKLRQMPQLFQELLEVICRPAAEALRQPLLASGLSMALCACFLELPLSQILD
TWSLVLDKFQSLVMPCLQSDTDMAFKAMSLSSLLHCIMFNMQSLDNNMPLPIIRRTQCMMERML
RELVKPLLGLLLDLWSPEPEPWQQKVSDSALLLSYTWAQVDTTLSLHCSQYYSLAVSLARAALD
SSNLPLLLPGVETELWKKVEKCIAQSRSLSRYCLEQLYLQKVKRTLIRTSSQSKEALQTLRFDT
AHILDSSRDCLSQKTVTAWDRQVSTMNESLYPVAHWHLIVSNLTVLIPYLCLNDVRYVATVLLR
TLPTSKAQGSLAPGESYVTLEKISTALLHSPLFPEMQSLYSAFLTCIIAKCSNILCSGAHNDLS
LSQQLPWLFGKDYHTLVAHWETRLAKVGSEGVEPRGEIAQNFLSMVKSGFPIKLHEDQLKDLLE
LFDVISALHLDSLWPSYHVHLFFLLFSMAVSTLGHCSCPLALQFLVKCYQLLSGLQRGRNARSV
FRVMYVSDIFEVVLTSLLQASAEFQVREDDPAWLQLLQVSGVFLEQLMQMLIQAKLSLVLNFGK
ITAFLSKYSKGASSKELNIQNLRSRQLLLVALTKLCQSLGPCVKERRQLLEAPAALPELLQQAM
MQMGAMLQLCLVPGTTGCRRRLPSVLLSAVPTLLEVDLSQHLREGQPKIAQVVDTDRALLSHVT
LYQDVYTQLLEELPALSGNTQSFQAALRFLTLFLLAPEFHSKESSVFASIFYSVQKVLTGPCIP
APVTQDTEPHLGALLTQMFKAETTEHFGMVLQSILQGLDVTQAWRSDLQVVLCAIRLLNLLLKC
PLSGEKASLLWRSCPQIVTALMLQHREACQEQPVALVVVEPILEVLAVLLRKGEESISNPHHVN
LAFNILLTVPLEHLKPREFGSVFLKTHNVLFSILQCHSKVMLKAIPSFLNSFNRLLLSVLHEGR
QKDQGSMDDLPVVLECARLVERMYSHIATRAEEFTTFSPFLVAQYVTEVQKVTLYPPVKNLLQE
GIYLILDLCMERDIQFLRASLQSGARDVFKDLHSDYLKYHKAKHEGEKRYTA

hide sequence

Ensembl Acc Id:

ENSRNOP00000029895 ⟸ ENSRNOT00000036042

RefSeq Acc Id:	XP_038953583 ⟸ XM_039097655
- Peptide Label:	isoform X1
- UniProtKB:	D4AAN0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063134025 ⟸ XM_063277955
- Peptide Label:	isoform X1
- UniProtKB:	D4AAN0 (UniProtKB/TrEMBL)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4AAN0-F1-model_v2	AlphaFold	D4AAN0	1-1569	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307980	AgrOrtholog
BioCyc Gene	G2FUF-5255	BioCyc
Ensembl Genes	ENSRNOG00000026853	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000036042	ENTREZGENE
	ENSRNOT00000036042.6	UniProtKB/TrEMBL
InterPro	27S_pre-rRNA_process_Urb2/Npa2	UniProtKB/TrEMBL
	Ribosome_Biogenesis_Reg	UniProtKB/TrEMBL
KEGG Report	rno:292087	UniProtKB/TrEMBL
NCBI Gene	292087	ENTREZGENE
PANTHER	UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG	UniProtKB/TrEMBL
	UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG	UniProtKB/TrEMBL
Pfam	Urb2	UniProtKB/TrEMBL
PhenoGen	Urb2	PhenoGen
RatGTEx	ENSRNOG00000026853	RatGTEx
UniProt	D4AAN0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-08-21	Urb2	URB2 ribosome biogenesis homolog	Urb2	URB2 ribosome biogenesis 2 homolog (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-10-16	Urb2	URB2 ribosome biogenesis 2 homolog (S. cerevisiae)	RGD1307980	similar to mKIAA0133 protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1307980	similar to mKIAA0133 protein	RGD1307980_predicted	similar to mKIAA0133 protein (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-20	RGD1307980_predicted	similar to mKIAA0133 protein (predicted)	LOC292087_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC292087_predicted	similar to mKIAA0133 protein (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar