Atp13a2 (ATPase cation transporting 13A2) - Rat Genome Database

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Gene: Atp13a2 (ATPase cation transporting 13A2) Rattus norvegicus
Analyze
Symbol: Atp13a2
Name: ATPase cation transporting 13A2
RGD ID: 1307977
Description: Predicted to enable ATPase-coupled monoatomic cation transmembrane transporter activity; phospholipid binding activity; and polyamine transmembrane transporter activity. Involved in regulation of autophagosome size and regulation of mitochondrion organization. Predicted to be located in several cellular components, including cytoplasmic vesicle; neuronal cell body; and vacuole. Predicted to be active in late endosome membrane. Human ortholog(s) of this gene implicated in Kufor-Rakeb syndrome; Parkinson's disease; and hereditary spastic paraplegia 78. Orthologous to human ATP13A2 (ATPase cation transporting 13A2); PARTICIPATES IN Parkinson's disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ATPase 13A2; ATPase type 13A2; LOC362645; MGC188455; polyamine-transporting ATPase 13A2; probable cation-transporting ATPase 13A2; RGD1307977; similar to RIKEN cDNA 1110012E06
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85158,575,727 - 158,595,157 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5158,575,749 - 158,595,156 (+)EnsemblGRCr8
mRatBN7.25153,292,722 - 153,312,143 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,292,751 - 153,312,139 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5155,981,005 - 156,000,631 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05157,754,276 - 157,773,902 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05157,743,460 - 157,763,086 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05159,512,208 - 159,531,631 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,512,285 - 159,531,637 (+)Ensemblrn6Rnor6.0
Rnor_5.05163,224,470 - 163,243,886 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45159,847,016 - 159,866,362 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5151,657,698 - 151,677,052 (+)NCBICelera
RGSC_v3.15159,857,176 - 159,876,542 (+)NCBI
Cytogenetic Map5q36NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Genes associated with Parkinson's disease: regulation of autophagy and beyond. Beilina A and Cookson MR, J Neurochem. 2015 Jul 30. doi: 10.1111/jnc.13266.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity. Ramonet D, etal., Hum Mol Genet. 2012 Apr 15;21(8):1725-43. doi: 10.1093/hmg/ddr606. Epub 2011 Dec 20.
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932   PMID:16964263   PMID:17897319   PMID:21542062   PMID:21724849   PMID:22198378   PMID:22285144   PMID:23205587   PMID:23499937   PMID:24334770   PMID:24603074   PMID:25392495  
PMID:26134396   PMID:26818499   PMID:27057733   PMID:27278822   PMID:30538141   PMID:31132336   PMID:31996848  


Genomics

Comparative Map Data
Atp13a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85158,575,727 - 158,595,157 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5158,575,749 - 158,595,156 (+)EnsemblGRCr8
mRatBN7.25153,292,722 - 153,312,143 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,292,751 - 153,312,139 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5155,981,005 - 156,000,631 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05157,754,276 - 157,773,902 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05157,743,460 - 157,763,086 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05159,512,208 - 159,531,631 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,512,285 - 159,531,637 (+)Ensemblrn6Rnor6.0
Rnor_5.05163,224,470 - 163,243,886 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45159,847,016 - 159,866,362 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5151,657,698 - 151,677,052 (+)NCBICelera
RGSC_v3.15159,857,176 - 159,876,542 (+)NCBI
Cytogenetic Map5q36NCBI
ATP13A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38116,985,958 - 17,011,928 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl116,985,958 - 17,011,928 (-)Ensemblhg38GRCh38
GRCh37117,312,453 - 17,338,423 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36117,185,040 - 17,210,854 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34117,057,758 - 17,083,573NCBI
Celera115,634,791 - 15,660,760 (-)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef115,556,532 - 15,582,505 (-)NCBIHuRef
CHM1_1117,420,791 - 17,446,761 (-)NCBICHM1_1
T2T-CHM13v2.0116,796,381 - 16,822,349 (-)NCBIT2T-CHM13v2.0
Atp13a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394140,711,812 - 140,734,641 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4140,714,184 - 140,734,641 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm384140,986,216 - 141,007,330 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4140,986,873 - 141,007,330 (+)Ensemblmm10GRCm38
MGSCv374140,542,788 - 140,563,616 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364140,259,004 - 140,279,406 (+)NCBIMGSCv36mm8
Celera4142,787,644 - 142,807,639 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map473.29NCBI
Atp13a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555271,806,009 - 1,823,344 (+)Ensembl
ChiLan1.0NW_0049555271,805,854 - 1,823,623 (+)NCBIChiLan1.0ChiLan1.0
ATP13A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21210,118,487 - 210,144,515 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11209,237,298 - 209,263,315 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0115,929,613 - 15,955,631 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1116,975,538 - 17,006,022 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl116,986,385 - 17,006,033 (-)EnsemblpanPan2panpan1.1
PanPan1.1 Ensembl116,975,544 - 17,006,022 (-)EnsemblpanPan2panpan1.1
ATP13A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1281,196,355 - 81,215,736 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl281,196,463 - 81,215,689 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha277,733,475 - 77,752,482 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0281,842,888 - 81,861,861 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl281,842,987 - 81,861,861 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1278,595,908 - 78,614,871 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0279,612,457 - 79,631,767 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0280,680,908 - 80,699,865 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Atp13a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505838,143,432 - 38,156,097 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364743,968,506 - 3,980,815 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364743,968,216 - 3,980,821 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP13A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl675,618,319 - 75,638,591 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1675,618,317 - 75,638,591 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2669,931,621 - 69,951,929 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATP13A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120115,578,185 - 115,605,416 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20115,578,261 - 115,605,647 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666033515,071 - 542,556 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atp13a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247642,614,827 - 2,631,793 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247642,614,541 - 2,631,972 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Atp13a2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1117,139,547 - 17,159,056 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Atp13a2
107 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:46
Count of miRNA genes:41
Interacting mature miRNAs:46
Transcripts:ENSRNOT00000010884
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116702075161702075Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5141212838172190305Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5149642129171146538Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5156396728172190305Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5149805999162987697Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5138002522170842766Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)5141764300172190305Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5148093485172129029Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5156396728167181764Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114131300159131300Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5149661912166600247Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116702075161702075Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116702075161702075Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116702075161702075Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5156289283171137955Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114131300159131300Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat

Markers in Region
RH134640  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25153,311,825 - 153,312,020 (+)MAPPERmRatBN7.2
Rnor_6.05159,531,317 - 159,531,511NCBIRnor6.0
Rnor_5.05163,243,569 - 163,243,763UniSTSRnor5.0
RGSC_v3.45159,866,048 - 159,866,242UniSTSRGSC3.4
Celera5151,676,738 - 151,676,932UniSTS
RH 3.4 Map51052.4UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001173432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC134642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC168672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000010884   ⟹   ENSRNOP00000010884
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5158,575,757 - 158,595,156 (+)Ensembl
mRatBN7.2 Ensembl5153,292,793 - 153,312,139 (+)Ensembl
Rnor_6.0 Ensembl5159,512,285 - 159,531,630 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000088082   ⟹   ENSRNOP00000070096
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5158,575,755 - 158,595,151 (+)Ensembl
mRatBN7.2 Ensembl5153,292,751 - 153,312,128 (+)Ensembl
Rnor_6.0 Ensembl5159,512,380 - 159,531,637 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114069   ⟹   ENSRNOP00000082003
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5158,575,749 - 158,595,156 (+)Ensembl
mRatBN7.2 Ensembl5153,292,873 - 153,312,139 (+)Ensembl
RefSeq Acc Id: NM_001173432   ⟹   NP_001166903
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,575,811 - 158,595,157 (+)NCBI
mRatBN7.25153,292,793 - 153,312,140 (+)NCBI
Rnor_6.05159,512,285 - 159,531,631 (+)NCBI
Rnor_5.05163,224,470 - 163,243,886 (+)NCBI
Celera5151,657,698 - 151,677,052 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239246   ⟹   XP_006239308
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,575,742 - 158,595,157 (+)NCBI
mRatBN7.25153,292,722 - 153,312,143 (+)NCBI
Rnor_6.05159,512,209 - 159,531,631 (+)NCBI
Rnor_5.05163,224,470 - 163,243,886 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239247   ⟹   XP_006239309
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,575,741 - 158,595,157 (+)NCBI
mRatBN7.25153,292,722 - 153,312,143 (+)NCBI
Rnor_6.05159,512,208 - 159,531,631 (+)NCBI
Rnor_5.05163,224,470 - 163,243,886 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239250   ⟹   XP_006239312
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,575,741 - 158,595,157 (+)NCBI
mRatBN7.25153,292,722 - 153,312,143 (+)NCBI
Rnor_6.05159,512,209 - 159,531,631 (+)NCBI
Rnor_5.05163,224,470 - 163,243,886 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239251   ⟹   XP_006239313
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,575,741 - 158,595,157 (+)NCBI
mRatBN7.25153,292,751 - 153,311,968 (+)NCBI
Rnor_6.05159,512,208 - 159,531,631 (+)NCBI
Rnor_5.05163,224,470 - 163,243,886 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063288077   ⟹   XP_063144147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,575,741 - 158,595,157 (+)NCBI
RefSeq Acc Id: XM_063288078   ⟹   XP_063144148
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,575,727 - 158,595,157 (+)NCBI
RefSeq Acc Id: XM_063288079   ⟹   XP_063144149
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,575,742 - 158,595,157 (+)NCBI
RefSeq Acc Id: XM_063288080   ⟹   XP_063144150
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,575,741 - 158,595,157 (+)NCBI
RefSeq Acc Id: XM_063288081   ⟹   XP_063144151
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,575,741 - 158,595,157 (+)NCBI
RefSeq Acc Id: XM_063288082   ⟹   XP_063144152
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,575,741 - 158,595,157 (+)NCBI
RefSeq Acc Id: NP_001166903   ⟸   NM_001173432
- UniProtKB: B5DEH6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239308   ⟸   XM_006239246
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006239312   ⟸   XM_006239250
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006239309   ⟸   XM_006239247
- Peptide Label: isoform X10
- UniProtKB: B5DEH6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239313   ⟸   XM_006239251
- Peptide Label: isoform X4
- Sequence:
Ensembl Acc Id: ENSRNOP00000010884   ⟸   ENSRNOT00000010884
Ensembl Acc Id: ENSRNOP00000070096   ⟸   ENSRNOT00000088082
Ensembl Acc Id: ENSRNOP00000082003   ⟸   ENSRNOT00000114069
RefSeq Acc Id: XP_063144148   ⟸   XM_063288078
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063144147   ⟸   XM_063288077
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063144151   ⟸   XM_063288081
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063144150   ⟸   XM_063288080
- Peptide Label: isoform X7
- UniProtKB: B5DEH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144152   ⟸   XM_063288082
- Peptide Label: isoform X9
- UniProtKB: B5DEH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144149   ⟸   XM_063288079
- Peptide Label: isoform X6
Protein Domains
P5B-type ATPase N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1MAA4-F1-model_v2 AlphaFold F1MAA4 1-1145 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694215
Promoter ID:EPDNEW_R4740
Type:multiple initiation site
Name:Atp13a2_1
Description:ATPase 13A2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05159,512,229 - 159,512,289EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307977 AgrOrtholog
BioCyc Gene G2FUF-39374 BioCyc
Ensembl Genes ENSRNOG00000008052 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010884 ENTREZGENE
  ENSRNOT00000010884.9 UniProtKB/TrEMBL
  ENSRNOT00000088082 ENTREZGENE
  ENSRNOT00000088082.3 UniProtKB/TrEMBL
  ENSRNOT00000114069 ENTREZGENE
  ENSRNOT00000114069.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.1110.10 UniProtKB/TrEMBL
  3.40.50.1000 UniProtKB/TrEMBL
  Calcium-transporting ATPase, cytoplasmic transduction domain A UniProtKB/TrEMBL
  Calcium-transporting ATPase, transmembrane domain UniProtKB/TrEMBL
InterPro ATPase_P-typ_ATPase-assoc-dom UniProtKB/TrEMBL
  ATPase_P-typ_cyto_domN UniProtKB/TrEMBL
  ATPase_P-typ_ion-transptr UniProtKB/TrEMBL
  ATPase_P-typ_P_site UniProtKB/TrEMBL
  ATPase_P-typ_TM_dom UniProtKB/TrEMBL
  ATPase_P-typ_unknown-pump-sp UniProtKB/TrEMBL
  HAD-like_sf UniProtKB/TrEMBL
  HAD_sf UniProtKB/TrEMBL
  P5A-ATPase_N UniProtKB/TrEMBL
  P5B-type_ATPase UniProtKB/TrEMBL
  P_typ_ATPase_HD_dom UniProtKB/TrEMBL
KEGG Report rno:362645 UniProtKB/TrEMBL
NCBI Gene 362645 ENTREZGENE
PANTHER CATION-TRANSPORTING ATPASE-RELATED UniProtKB/TrEMBL
  POLYAMINE-TRANSPORTING ATPASE 13A2 UniProtKB/TrEMBL
Pfam E1-E2_ATPase UniProtKB/TrEMBL
  Hydrolase UniProtKB/TrEMBL
  P5-ATPase UniProtKB/TrEMBL
PhenoGen Atp13a2 PhenoGen
PRINTS CATATPASE UniProtKB/TrEMBL
  HATPASE UniProtKB/TrEMBL
PROSITE ATPASE_E1_E2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008052 RatGTEx
Superfamily-SCOP ATPase_cation_domN UniProtKB/TrEMBL
  HAD-like_dom UniProtKB/TrEMBL
  SSF81653 UniProtKB/TrEMBL
  SSF81665 UniProtKB/TrEMBL
UniProt A0A0G2JX15 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZTP8_RAT UniProtKB/TrEMBL
  B5DEH6 ENTREZGENE, UniProtKB/TrEMBL
  F1MAA4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-03-13 Atp13a2  ATPase cation transporting 13A2  Atp13a2  ATPase 13A2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-17 Atp13a2  ATPase 13A2  Atp13a2  ATPase type 13A2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Atp13a2  ATPase type 13A2   Atp13a2_predicted  ATPase type 13A2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Atp13a2_predicted  ATPase type 13A2 (predicted)  RGD1307977_predicted  similar to RIKEN cDNA 1110012E06 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1307977_predicted  similar to RIKEN cDNA 1110012E06 (predicted)  LOC362645_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC362645_predicted  similar to RIKEN cDNA 1110012E06 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL