Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Tbc1d15 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of TBC1D15 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Tbc1d15 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TBC1D15 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | multiple interactions | ISO | Tbc1d15 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TBC1D15 mRNA | CTD | PMID:17942748 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of TBC1D15 mRNA | CTD | PMID:32145629 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Tbc1d15 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TBC1D15 mRNA | CTD | PMID:19465110 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TBC1D15 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tbc1d15 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TBC1D15 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Tbc1d15 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TBC1D15 mRNA | CTD | PMID:19770486 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Tbc1d15 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TBC1D15 mRNA | CTD | PMID:17942748 | acrolein | multiple interactions | ISO | TBC1D15 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TBC1D15 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TBC1D15 mRNA | CTD | PMID:32699268 | aflatoxin B1 | increases methylation | ISO | TBC1D15 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of TBC1D15 gene | CTD | PMID:27153756 | aflatoxin B1 | decreases methylation | ISO | TBC1D15 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TBC1D15 intron | CTD | PMID:30157460 | aflatoxin M1 | decreases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of TBC1D15 mRNA | CTD | PMID:30928695 | all-trans-retinoic acid | decreases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of TBC1D15 mRNA | CTD | PMID:33167477 | alpha-pinene | multiple interactions | ISO | TBC1D15 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TBC1D15 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TBC1D15 mRNA | CTD | PMID:32699268 | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of TBC1D15 mRNA | CTD | PMID:30779732 | aristolochic acid A | decreases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of TBC1D15 mRNA | CTD | PMID:33212167 | arsenous acid | increases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of TBC1D15 mRNA | CTD | PMID:20458559 | auramine O | increases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Benzophenoneidum results in increased expression of TBC1D15 protein | CTD | PMID:28722353 | benzo[a]pyrene | increases expression | ISO | Tbc1d15 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of TBC1D15 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | affects methylation | ISO | TBC1D15 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TBC1D15 promoter | CTD | PMID:27901495 | benzo[e]pyrene | increases methylation | ISO | TBC1D15 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of TBC1D15 intron | CTD | PMID:30157460 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TBC1D15 mRNA | CTD | PMID:25181051 more ... | cadmium atom | decreases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Cadmium results in decreased expression of TBC1D15 mRNA | CTD | PMID:23369406 | carbon nanotube | increases expression | ISO | Tbc1d15 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in increased expression of TBC1D15 mRNA | CTD | PMID:25620056 | clorgyline | increases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Clorgyline results in increased expression of TBC1D15 mRNA | CTD | PMID:19691856 | clozapine | increases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Clozapine results in increased expression of TBC1D15 protein | CTD | PMID:36482696 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of TBC1D15 mRNA | CTD | PMID:24386269 | cobalt dichloride | increases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of TBC1D15 mRNA | CTD | PMID:19320972 | copper(II) sulfate | increases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of TBC1D15 mRNA | CTD | PMID:19549813 | coumarin | decreases phosphorylation | ISO | TBC1D15 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of TBC1D15 protein | CTD | PMID:35688186 | crocidolite asbestos | decreases expression | ISO | Tbc1d15 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of TBC1D15 mRNA | CTD | PMID:29279043 | CU-O LINKAGE | increases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | cupric oxide results in increased expression of TBC1D15 mRNA | CTD | PMID:22077320 | cyclosporin A | increases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of TBC1D15 mRNA | CTD | PMID:20106945 more ... | deoxynivalenol | decreases phosphorylation | ISO | Tbc1d15 (Mus musculus) | 6480464 | deoxynivalenol results in decreased phosphorylation of TBC1D15 protein | CTD | PMID:23352502 | dextran sulfate | multiple interactions | ISO | Tbc1d15 (Mus musculus) | 6480464 | Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of TBC1D15 protein] | CTD | PMID:32272095 | dextran sulfate | decreases expression | ISO | Tbc1d15 (Mus musculus) | 6480464 | Dextran Sulfate results in decreased expression of TBC1D15 protein | CTD | PMID:32272095 | diarsenic trioxide | increases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of TBC1D15 mRNA | CTD | PMID:20458559 | dicrotophos | decreases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of TBC1D15 mRNA | CTD | PMID:28302478 | dorsomorphin | multiple interactions | ISO | TBC1D15 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | enzyme inhibitor | multiple interactions | ISO | TBC1D15 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of TBC1D15 protein | CTD | PMID:23301498 | epoxiconazole | decreases expression | ISO | Tbc1d15 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of TBC1D15 mRNA | CTD | PMID:35436446 | ethanol | affects splicing | ISO | Tbc1d15 (Mus musculus) | 6480464 | Ethanol affects the splicing of TBC1D15 mRNA | CTD | PMID:30319688 | fluoranthene | multiple interactions | ISO | Tbc1d15 (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of TBC1D15 mRNA | CTD | PMID:28329830 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of TBC1D15 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Tbc1d15 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TBC1D15 mRNA | CTD | PMID:22206623 | folic acid | decreases expression | ISO | Tbc1d15 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of TBC1D15 mRNA | CTD | PMID:25629700 | FR900359 | affects phosphorylation | ISO | TBC1D15 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of TBC1D15 protein | CTD | PMID:37730182 | gallic acid | increases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Gallic Acid results in increased expression of TBC1D15 mRNA | CTD | PMID:34408198 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of TBC1D15 mRNA | CTD | PMID:22061828 and PMID:33387578 | hydrogen peroxide | multiple interactions | ISO | Tbc1d15 (Mus musculus) | 6480464 | [Hydrogen Peroxide co-treated with N-(oxo-5 more ... | CTD | PMID:31494107 | isoprenaline | increases expression | ISO | Tbc1d15 (Mus musculus) | 6480464 | Isoproterenol results in increased expression of TBC1D15 mRNA | CTD | PMID:20003209 | ivermectin | decreases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of TBC1D15 protein | CTD | PMID:32959892 | methapyrilene | increases methylation | ISO | TBC1D15 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of TBC1D15 intron | CTD | PMID:30157460 | methyl methanesulfonate | increases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of TBC1D15 mRNA | CTD | PMID:23649840 | methylparaben | increases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | methylparaben results in increased expression of TBC1D15 mRNA | CTD | PMID:31745603 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of TBC1D15 mRNA | CTD | PMID:24136188 | ozone | multiple interactions | ISO | TBC1D15 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TBC1D15 mRNA more ... | CTD | PMID:32699268 | paracetamol | affects expression | ISO | Tbc1d15 (Mus musculus) | 6480464 | Acetaminophen affects the expression of TBC1D15 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of TBC1D15 mRNA | CTD | PMID:29067470 | phenobarbital | affects expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of TBC1D15 mRNA | CTD | PMID:19159669 | phenobarbital | affects expression | ISO | Tbc1d15 (Mus musculus) | 6480464 | Phenobarbital affects the expression of TBC1D15 mRNA | CTD | PMID:23091169 | phenylmercury acetate | decreases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of TBC1D15 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | TBC1D15 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TBC1D15 mRNA | CTD | PMID:27188386 | pirinixic acid | increases expression | ISO | Tbc1d15 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of TBC1D15 mRNA | CTD | PMID:17426115 and PMID:23811191 | SB 431542 | multiple interactions | ISO | TBC1D15 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | multiple interactions | ISO | TBC1D15 (Homo sapiens) | 6480464 | sodium arsenite promotes the reaction [TBC1D15 protein binds to CAPRIN1 protein] | CTD | PMID:33939924 | sodium fluoride | decreases expression | ISO | Tbc1d15 (Mus musculus) | 6480464 | Sodium Fluoride results in decreased expression of TBC1D15 mRNA | CTD | PMID:27862939 | tetrachloroethene | increases expression | ISO | Tbc1d15 (Mus musculus) | 6480464 | Tetrachloroethylene results in increased expression of TBC1D15 mRNA | CTD | PMID:28973375 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of TBC1D15 mRNA | CTD | PMID:31150632 | tetrachloromethane | increases expression | ISO | Tbc1d15 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of TBC1D15 mRNA | CTD | PMID:31919559 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of TBC1D15 mRNA | CTD | PMID:34492290 | trichostatin A | decreases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of TBC1D15 mRNA | CTD | PMID:24935251 | tunicamycin | increases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of TBC1D15 mRNA | CTD | PMID:22378314 | valdecoxib | increases expression | EXP | | 6480464 | valdecoxib results in increased expression of TBC1D15 mRNA | CTD | PMID:24136188 | valproic acid | increases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TBC1D15 mRNA | CTD | PMID:29154799 | valproic acid | decreases methylation | ISO | TBC1D15 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of TBC1D15 gene | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | TBC1D15 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of TBC1D15 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | TBC1D15 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TBC1D15 mRNA | CTD | PMID:27188386 | |