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Gene: Sema4b (semaphorin 4B) Rattus norvegicus

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Symbol:

Sema4b

Name:

semaphorin 4B

RGD ID:

1307872

Description:

Predicted to enable chemorepellent activity; neuropilin binding activity; and semaphorin receptor binding activity. Predicted to be involved in several processes, including axon guidance; neural crest cell migration; and semaphorin-plexin signaling pathway. Predicted to be located in membrane and synapse. Predicted to be active in glutamatergic synapse and postsynaptic density membrane. Orthologous to human SEMA4B (semaphorin 4B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; alpha-Zearalanol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC293042; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B; semaphorin-4B

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	143,545,727 - 143,587,037 (+)	NCBI		GRCr8
mRatBN7.2	1	134,136,646 - 134,177,777 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	134,149,536 - 134,177,775 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	142,058,363 - 142,086,508 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	149,227,763 - 149,255,908 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	142,145,557 - 142,173,801 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	141,986,145 - 142,014,400 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	141,986,145 - 142,014,398 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	142,941,088 - 142,968,795 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	136,001,219 - 136,031,302 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	136,079,624 - 136,109,702 (+)	NCBI
Celera	1	126,209,674 - 126,237,909 (+)	NCBI		Celera
Cytogenetic Map	1	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Sema4b	Rat	Bloom syndrome		ISO	SEMA4B (Homo sapiens)	8554872	ClinVar Annotator: match by term: Bloom syndrome	ClinVar	PMID:17407155 and PMID:28492532
Sema4b	Rat	colorectal cancer		ISO	SEMA4B (Homo sapiens)	8554872	ClinVar Annotator: match by term: Familial colorectal cancer	ClinVar	PMID:28492532
Sema4b	Rat	D-2-hydroxyglutaric aciduria 2		ISO	SEMA4B (Homo sapiens)	8554872	ClinVar Annotator: match by term: D-2-hydroxyglutaric aciduria 2	ClinVar	PMID:17407155 and PMID:28492532

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Sema4b	Rat	17beta-estradiol	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	Estradiol results in decreased expression of SEMA4B mRNA	CTD	PMID:24758408
Sema4b	Rat	17beta-estradiol	multiple interactions	ISO	SEMA4B (Homo sapiens)	6480464	EGF protein inhibits the reaction [Estradiol results in decreased expression of SEMA4B mRNA]	CTD	PMID:24758408
Sema4b	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	EXP		6480464	Tetrachlorodibenzodioxin affects the expression of SEMA4B mRNA	CTD	PMID:22298810
Sema4b	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	Sema4b (Mus musculus)	6480464	Tetrachlorodibenzodioxin affects the expression of SEMA4B mRNA	CTD	PMID:21570461
Sema4b	Rat	2-methylcholine	affects expression	ISO	SEMA4B (Homo sapiens)	6480464	beta-methylcholine affects the expression of SEMA4B mRNA	CTD	PMID:21179406
Sema4b	Rat	3,4-methylenedioxymethamphetamine	decreases expression	ISO	Sema4b (Mus musculus)	6480464	N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of SEMA4B mRNA	CTD	PMID:26251327
Sema4b	Rat	4,4'-sulfonyldiphenol	decreases expression	ISO	Sema4b (Mus musculus)	6480464	bisphenol S results in decreased expression of SEMA4B mRNA	CTD	PMID:39298647
Sema4b	Rat	4,4'-sulfonyldiphenol	decreases methylation	ISO	SEMA4B (Homo sapiens)	6480464	bisphenol S results in decreased methylation of SEMA4B gene	CTD	PMID:31601247
Sema4b	Rat	6-propyl-2-thiouracil	affects expression	EXP		6480464	Propylthiouracil affects the expression of SEMA4B mRNA	CTD	PMID:24780913
Sema4b	Rat	6-propyl-2-thiouracil	decreases expression	EXP		6480464	Propylthiouracil results in decreased expression of SEMA4B mRNA	CTD	PMID:30047161 and PMID:36843608
Sema4b	Rat	acetazolamide	increases expression	ISO	Sema4b (Mus musculus)	6480464	Acetazolamide results in increased expression of SEMA4B mRNA	CTD	PMID:19274763
Sema4b	Rat	all-trans-retinoic acid	increases expression	ISO	SEMA4B (Homo sapiens)	6480464	Tretinoin results in increased expression of SEMA4B mRNA	CTD	PMID:33167477
Sema4b	Rat	alpha-Zearalanol	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] results in increased expression of SEMA4B mRNA	CTD	PMID:35163327
Sema4b	Rat	amitrole	decreases expression	EXP		6480464	Amitrole results in decreased expression of SEMA4B mRNA	CTD	PMID:30047161
Sema4b	Rat	antirheumatic drug	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	Antirheumatic Agents results in decreased expression of SEMA4B mRNA	CTD	PMID:24449571
Sema4b	Rat	arsane	affects methylation	ISO	SEMA4B (Homo sapiens)	6480464	Arsenic affects the methylation of SEMA4B gene	CTD	PMID:25304211
Sema4b	Rat	arsenic atom	affects methylation	ISO	SEMA4B (Homo sapiens)	6480464	Arsenic affects the methylation of SEMA4B gene	CTD	PMID:25304211
Sema4b	Rat	azoxystrobin	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	azoxystrobin results in decreased expression of SEMA4B mRNA	CTD	PMID:33512557
Sema4b	Rat	benzo[a]pyrene	affects methylation	ISO	SEMA4B (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of SEMA4B 5' UTR and Benzo(a)pyrene affects the methylation of SEMA4B promoter	CTD	PMID:27901495
Sema4b	Rat	beta-lapachone	increases expression	ISO	SEMA4B (Homo sapiens)	6480464	beta-lapachone results in increased expression of SEMA4B mRNA	CTD	PMID:38218311
Sema4b	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of SEMA4B mRNA	CTD	PMID:25181051 and PMID:34947998
Sema4b	Rat	bisphenol A	increases expression	ISO	SEMA4B (Homo sapiens)	6480464	bisphenol A results in increased expression of SEMA4B mRNA	CTD	PMID:33670352
Sema4b	Rat	butan-1-ol	multiple interactions	ISO	SEMA4B (Homo sapiens)	6480464	[[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of SEMA4B mRNA	CTD	PMID:29432896
Sema4b	Rat	butanal	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	butyraldehyde results in decreased expression of SEMA4B mRNA	CTD	PMID:26079696
Sema4b	Rat	cadmium dichloride	increases expression	ISO	SEMA4B (Homo sapiens)	6480464	Cadmium Chloride results in increased expression of SEMA4B mRNA	CTD	PMID:38382870
Sema4b	Rat	caffeine	increases phosphorylation	ISO	SEMA4B (Homo sapiens)	6480464	Caffeine results in increased phosphorylation of SEMA4B protein	CTD	PMID:35688186
Sema4b	Rat	calcitriol	increases expression	ISO	SEMA4B (Homo sapiens)	6480464	Calcitriol results in increased expression of SEMA4B mRNA	CTD	PMID:16002434 and PMID:26485663
Sema4b	Rat	carbon nanotube	increases expression	ISO	Sema4b (Mus musculus)	6480464	Nanotubes more ...	CTD	PMID:25620056
Sema4b	Rat	CGP 52608	multiple interactions	ISO	SEMA4B (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to SEMA4B gene]	CTD	PMID:28238834
Sema4b	Rat	chlorpyrifos	increases expression	ISO	Sema4b (Mus musculus)	6480464	Chlorpyrifos results in increased expression of SEMA4B mRNA	CTD	PMID:20350560 and PMID:37019170
Sema4b	Rat	cocaine	increases expression	EXP		6480464	Cocaine results in increased expression of SEMA4B mRNA	CTD	PMID:15691709
Sema4b	Rat	Cuprizon	affects expression	EXP		6480464	Cuprizone affects the expression of SEMA4B mRNA	CTD	PMID:26577399
Sema4b	Rat	cyclosporin A	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	Cyclosporine results in decreased expression of SEMA4B mRNA	CTD	PMID:20106945
Sema4b	Rat	deguelin	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	deguelin results in decreased expression of SEMA4B mRNA	CTD	PMID:33512557
Sema4b	Rat	diclofenac	increases expression	ISO	Sema4b (Mus musculus)	6480464	Diclofenac results in increased expression of SEMA4B mRNA	CTD	PMID:26934552
Sema4b	Rat	dioxygen	increases expression	ISO	SEMA4B (Homo sapiens)	6480464	Oxygen deficiency results in increased expression of SEMA4B mRNA	CTD	PMID:26516004
Sema4b	Rat	doxorubicin	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	Doxorubicin results in decreased expression of SEMA4B mRNA	CTD	PMID:29803840
Sema4b	Rat	ethanol	increases expression	ISO	Sema4b (Mus musculus)	6480464	Ethanol results in increased expression of SEMA4B mRNA	CTD	PMID:30319688
Sema4b	Rat	fenpyroximate	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	fenpyroximate results in decreased expression of SEMA4B mRNA	CTD	PMID:33512557
Sema4b	Rat	fenthion	decreases expression	ISO	Sema4b (Mus musculus)	6480464	Fenthion results in decreased expression of SEMA4B mRNA	CTD	PMID:34813904
Sema4b	Rat	glycidol	decreases expression	EXP		6480464	glycidol results in decreased expression of SEMA4B mRNA	CTD	PMID:24915197
Sema4b	Rat	iron dichloride	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	ferrous chloride results in decreased expression of SEMA4B mRNA	CTD	PMID:35984750
Sema4b	Rat	ivermectin	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	Ivermectin results in decreased expression of SEMA4B protein	CTD	PMID:32959892
Sema4b	Rat	methidathion	decreases expression	ISO	Sema4b (Mus musculus)	6480464	methidathion results in decreased expression of SEMA4B mRNA	CTD	PMID:34813904
Sema4b	Rat	methimazole	decreases expression	EXP		6480464	Methimazole results in decreased expression of SEMA4B mRNA	CTD	PMID:30047161
Sema4b	Rat	oxaliplatin	multiple interactions	EXP		6480464	[oxaliplatin co-treated with Topotecan] results in decreased expression of SEMA4B mRNA	CTD	PMID:25729387
Sema4b	Rat	ozone	multiple interactions	ISO	SEMA4B (Homo sapiens)	6480464	[Air Pollutants results in increased abundance of Ozone] which affects the expression of SEMA4B mRNA	CTD	PMID:35430440
Sema4b	Rat	paracetamol	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	Acetaminophen results in decreased expression of SEMA4B mRNA	CTD	PMID:21420995 and PMID:29067470
Sema4b	Rat	perfluorohexanesulfonic acid	decreases expression	ISO	Sema4b (Mus musculus)	6480464	perfluorohexanesulfonic acid results in decreased expression of SEMA4B mRNA	CTD	PMID:37995155
Sema4b	Rat	perfluorononanoic acid	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	perfluoro-n-nonanoic acid results in decreased expression of SEMA4B mRNA	CTD	PMID:32588087
Sema4b	Rat	perfluorooctanoic acid	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] results in increased expression of SEMA4B mRNA	CTD	PMID:35163327
Sema4b	Rat	picoxystrobin	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	picoxystrobin results in decreased expression of SEMA4B mRNA	CTD	PMID:33512557
Sema4b	Rat	progesterone	affects expression	ISO	Sema4b (Mus musculus)	6480464	Progesterone affects the expression of SEMA4B mRNA	CTD	PMID:17251523
Sema4b	Rat	pyrimidifen	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	pyrimidifen results in decreased expression of SEMA4B mRNA	CTD	PMID:33512557
Sema4b	Rat	raloxifene	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	Raloxifene Hydrochloride results in decreased expression of SEMA4B mRNA	CTD	PMID:19429434
Sema4b	Rat	senecionine	decreases expression	ISO	Sema4b (Mus musculus)	6480464	senecionine results in decreased expression of SEMA4B protein	CTD	PMID:35357534
Sema4b	Rat	silicon dioxide	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	Silicon Dioxide analog results in decreased expression of SEMA4B mRNA	CTD	PMID:25895662
Sema4b	Rat	sodium arsenite	multiple interactions	ISO	SEMA4B (Homo sapiens)	6480464	sodium arsenite results in decreased expression of and affects the splicing of SEMA4B mRNA	CTD	PMID:25879800
Sema4b	Rat	sodium arsenite	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	sodium arsenite results in decreased expression of SEMA4B mRNA	CTD	PMID:38568856
Sema4b	Rat	sulfadimethoxine	decreases expression	EXP		6480464	Sulfadimethoxine results in decreased expression of SEMA4B mRNA	CTD	PMID:30047161
Sema4b	Rat	tamoxifen	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	Tamoxifen results in decreased expression of SEMA4B mRNA	CTD	PMID:19429434
Sema4b	Rat	tebufenpyrad	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of SEMA4B mRNA	CTD	PMID:33512557
Sema4b	Rat	temozolomide	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	Temozolomide results in decreased expression of SEMA4B mRNA	CTD	PMID:31758290
Sema4b	Rat	thiram	decreases expression	ISO	SEMA4B (Homo sapiens)	6480464	Thiram results in decreased expression of SEMA4B mRNA	CTD	PMID:38568856
Sema4b	Rat	titanium dioxide	decreases expression	ISO	Sema4b (Mus musculus)	6480464	titanium dioxide results in decreased expression of SEMA4B mRNA	CTD	PMID:29264374
Sema4b	Rat	titanium dioxide	decreases methylation	ISO	Sema4b (Mus musculus)	6480464	titanium dioxide results in decreased methylation of SEMA4B gene and titanium dioxide results in decreased methylation of SEMA4B promoter	CTD	PMID:35295148
Sema4b	Rat	topotecan	decreases expression	EXP		6480464	Topotecan results in decreased expression of SEMA4B mRNA	CTD	PMID:25729387
Sema4b	Rat	topotecan	multiple interactions	EXP		6480464	[oxaliplatin co-treated with Topotecan] results in decreased expression of SEMA4B mRNA	CTD	PMID:25729387
Sema4b	Rat	trichloroethene	increases expression	EXP		6480464	Trichloroethylene results in increased expression of SEMA4B mRNA	CTD	PMID:33387578
Sema4b	Rat	triphenyl phosphate	affects expression	ISO	SEMA4B (Homo sapiens)	6480464	triphenyl phosphate affects the expression of SEMA4B mRNA	CTD	PMID:37042841
Sema4b	Rat	tris(2-butoxyethyl) phosphate	affects expression	ISO	SEMA4B (Homo sapiens)	6480464	tris(2-butoxyethyl) phosphate affects the expression of SEMA4B mRNA	CTD	PMID:29024780
Sema4b	Rat	trovafloxacin	increases expression	ISO	Sema4b (Mus musculus)	6480464	trovafloxacin results in increased expression of SEMA4B mRNA	CTD	PMID:35537566
Sema4b	Rat	tungsten	decreases expression	ISO	Sema4b (Mus musculus)	6480464	Tungsten results in decreased expression of SEMA4B mRNA	CTD	PMID:30912803
Sema4b	Rat	urethane	increases expression	ISO	SEMA4B (Homo sapiens)	6480464	Urethane results in increased expression of SEMA4B mRNA	CTD	PMID:28818685
Sema4b	Rat	vinclozolin	increases expression	EXP		6480464	vinclozolin results in increased expression of SEMA4B mRNA	CTD	PMID:23869203
Sema4b	Rat	vinclozolin	decreases methylation	EXP		6480464	vinclozolin results in decreased methylation of SEMA4B gene	CTD	PMID:31079544
Sema4b	Rat	zinc atom	multiple interactions	ISO	SEMA4B (Homo sapiens)	6480464	[PCI 5002 co-treated with Zinc] results in increased expression of SEMA4B mRNA	CTD	PMID:18593933
Sema4b	Rat	zinc(0)	multiple interactions	ISO	SEMA4B (Homo sapiens)	6480464	[PCI 5002 co-treated with Zinc] results in increased expression of SEMA4B mRNA	CTD	PMID:18593933

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Sema4b	Rat	axon guidance	involved_in	IBA	FB:FBgn0011259 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Sema4b	Rat	cell differentiation	involved_in	IEA	UniProtKB-KW:KW-0221	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Sema4b	Rat	negative chemotaxis	involved_in	IBA	FB:FBgn0011260 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Sema4b	Rat	nervous system development	involved_in	IEA	UniProtKB-KW:KW-0524	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Sema4b	Rat	neural crest cell migration	involved_in	IBA	MGI:107557 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Sema4b	Rat	positive regulation of cell migration	involved_in	IBA	MGI:107556 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Sema4b	Rat	regulation of plasma membrane bounded cell projection organization	involved_in	IEA	ARBA:ARBA00028050	1600115	GO_REF:0000117	UniProt	GO_REF:0000117
Sema4b	Rat	semaphorin-plexin signaling pathway	involved_in	IBA	FB:FBgn0011259 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Sema4b	Rat	glutamatergic synapse	is_active_in	ISO	Sema4b (Mus musculus)	1624291	PMID:15978582	RGD	PMID:15978582
Sema4b	Rat	glutamatergic synapse	is_active_in	IEA	UniProtKB:Q62179 and ensembl:ENSMUSP00000032754	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Sema4b	Rat	membrane	located_in	IEA	UniProtKB:Q62179 and ensembl:ENSMUSP00000032754	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Sema4b	Rat	membrane	located_in	ISO	Sema4b (Mus musculus)	1624291	PMID:15978582	RGD	PMID:15978582
Sema4b	Rat	membrane	located_in	IEA	UniProtKB-SubCell:SL-0162	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Sema4b	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Sema4b	Rat	plasma membrane	is_active_in	IBA	MGI:107559 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Sema4b	Rat	plasma membrane	located_in	IEA	UniProtKB:Q62179 and ensembl:ENSMUSP00000032754	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Sema4b	Rat	plasma membrane	located_in	ISO	Sema4b (Mus musculus)	1624291	PMID:15978582	RGD	PMID:15978582
Sema4b	Rat	postsynaptic density membrane	is_active_in	ISO	Sema4b (Mus musculus)	1624291	PMID:15978582	RGD	PMID:15978582
Sema4b	Rat	postsynaptic density membrane	is_active_in	IEA	UniProtKB:Q62179 and ensembl:ENSMUSP00000032754	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Sema4b	Rat	synapse	located_in	ISO	Sema4b (Mus musculus)	1624291	PMID:15978582	RGD	PMID:15978582
Sema4b	Rat	synapse	located_in	IEA	UniProtKB:Q62179 and ensembl:ENSMUSP00000032754	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Sema4b	Rat	chemorepellent activity	enables	IBA	MGI:107558 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Sema4b	Rat	neuropilin binding	enables	IBA	MGI:107558 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Sema4b	Rat	protein binding	enables	ISO	SEMA4B (Homo sapiens)	1624291	UniProtKB:P0DTD8 more ...	RGD	PMID:33845483 more ...
Sema4b	Rat	protein binding	enables	ISO	Sema4b (Mus musculus)	1624291	PR:Q62108 more ...	RGD	PMID:15978582
Sema4b	Rat	semaphorin receptor binding	enables	IBA	MGI:107556 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Sema4b	Rat	semaphorin receptor binding	enables	IEA	InterPro:IPR027231	1600115	GO_REF:0000002	InterPro	GO_REF:0000002

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

PMID:8889548	PMID:15978582

Sema4b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	143,545,727 - 143,587,037 (+)	NCBI		GRCr8
mRatBN7.2	1	134,136,646 - 134,177,777 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	134,149,536 - 134,177,775 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	142,058,363 - 142,086,508 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	149,227,763 - 149,255,908 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	142,145,557 - 142,173,801 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	141,986,145 - 142,014,400 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	141,986,145 - 142,014,398 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	142,941,088 - 142,968,795 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	136,001,219 - 136,031,302 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	136,079,624 - 136,109,702 (+)	NCBI
Celera	1	126,209,674 - 126,237,909 (+)	NCBI		Celera
Cytogenetic Map	1	q31	NCBI

SEMA4B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	90,184,920 - 90,229,661 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	90,160,604 - 90,229,679 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	90,728,152 - 90,772,893 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	88,529,156 - 88,573,896 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	88,545,565 - 88,573,894	NCBI
Celera	15	67,132,562 - 67,177,271 (+)	NCBI		Celera
Cytogenetic Map	15	q26.1	NCBI
HuRef	15	66,840,233 - 66,884,886 (+)	NCBI		HuRef
CHM1_1	15	90,570,020 - 90,614,740 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	87,940,946 - 87,985,668 (+)	NCBI		T2T-CHM13v2.0

Sema4b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	79,836,618 - 79,876,394 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	79,836,589 - 79,876,275 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	80,186,870 - 80,226,646 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	80,186,841 - 80,226,527 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	87,331,727 - 87,371,410 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	80,072,038 - 80,099,907 (+)	NCBI		MGSCv36	mm8
Celera	7	77,588,064 - 77,627,863 (+)	NCBI		Celera
Cytogenetic Map	7	D2	NCBI
cM Map	7	45.51	NCBI

Sema4b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955416	15,108,175 - 15,130,746 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955416	15,107,258 - 15,143,338 (-)	NCBI	ChiLan1.0	ChiLan1.0

SEMA4B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	79,733,117 - 79,777,995 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	83,432,586 - 83,477,430 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	68,873,927 - 68,918,792 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	88,076,399 - 88,120,729 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	88,076,399 - 88,120,729 (+)	Ensembl	panpan1.1		panPan2

SEMA4B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	53,159,233 - 53,184,102 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	53,121,775 - 53,184,118 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	55,751,921 - 55,822,246 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	53,575,541 - 53,600,478 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	53,575,536 - 53,600,127 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	53,050,291 - 53,120,581 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	53,306,792 - 53,331,717 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	53,647,261 - 53,672,192 (+)	NCBI		UU_Cfam_GSD_1.0

Sema4b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	130,371,613 - 130,410,098 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936483	15,937,398 - 15,961,911 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936483	15,937,132 - 15,963,170 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SEMA4B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	55,753,097 - 55,793,980 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	55,752,854 - 55,793,982 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SEMA4B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	29	8,733,647 - 8,776,618 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	29	8,749,015 - 8,775,621 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666059	37,953,982 - 37,981,988 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sema4b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624768	17,185,161 - 17,207,666 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624768	17,170,732 - 17,208,601 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Sema4b
244 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	44
Count of miRNA genes:	43
Interacting mature miRNAs:	44
Transcripts:	ENSRNOT00000030914
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61442	Strs1	Sensitivity to stroke QTL 1	7.4		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	1	121767634	166767634	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49393172	159356837	Rat
1598866	Bp287	Blood pressure QTL 287	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	121006655	166006655	Rat
1578770	Stresp23	Stress response QTL 23			kidney sympathetic nerve activity (VT:0004050)	stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)	1	123350408	182418476	Rat
9590300	Scort16	Serum corticosterone level QTL 16	4.39	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	103111621	148111621	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	57336763	151090257	Rat
7794788	Mcs32	Mammary carcinoma susceptibility QTL 32	2.61		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	1	115540693	238914717	Rat
631199	Cm23	Cardiac mass QTL 23	4.6	0.0004	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	115585465	172949803	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	48963584	144267916	Rat
1598850	Bp297	Blood pressure QTL 297	2.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	121006655	166006655	Rat
631570	Bp94	Blood pressure QTL 94		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123479780	142990467	Rat
152025235	Bw194	Body weight QTL 194	4.86		body mass (VT:0001259)		1	123556856	242907031	Rat
152025232	Bw192	Body weight QTL 192	3.93		body mass (VT:0001259)		1	117917486	196963478	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	90508614	173018436	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	90508614	180359386	Rat
61346	Rf2	Renal disease susceptibility QTL 2	3.7		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	1	99267916	144267916	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	100357752	183970443	Rat
1300153	Bp171	Blood pressure QTL 171	3.37		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	90664883	143200202	Rat
2317833	Alcrsp19	Alcohol response QTL 19	12.4	0.001	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	1	100979852	145979852	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94642644	214537671	Rat
631202	Gluco13	Glucose level QTL 13		0.0001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	131763437	159756369	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118944897	199050459	Rat
1300158	Bp173	Blood pressure QTL 173	3.48		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	1	115540693	185145286	Rat
1641897	Alcrsp1	Alcohol response QTL 1			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	1	100979852	145979852	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	94494440	198211706	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	94494440	181830018	Rat
2293142	Bp314	Blood pressure QTL 314			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	92184926	137184926	Rat
9685799	Bp375	Blood pressure QTL 375			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	125611501	170611501	Rat
2293140	Bp313	Blood pressure QTL 313			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	121833674	166833674	Rat
9685802	Bp376	Blood pressure QTL 376			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	126540680	171540680	Rat
724529	Cm16	Cardiac mass QTL 16	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	1	87580395	150700247	Rat
61370	Mcs3	Mammary carcinoma susceptibility QTL 3	2.15		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	102268556	147268556	Rat
1641895	Bp298	Blood pressure QTL 298			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	123350408	182418476	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	94494440	198324465	Rat
631496	Bp97	Blood pressure QTL 97	3.08		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	106047847	151047847	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
2303591	Gluco41	Glucose level QTL 41	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	102168504	147168504	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94494440	172949803	Rat
2313060	Bss71	Bone structure and strength QTL 71	2.6	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	1	118944747	163944747	Rat
6893347	Bw98	Body weight QTL 98	0.2	0.53	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	102813953	201278233	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118608292	241799120	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32356093	162846471	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
61399	Tcat1	Tongue tumor resistance QTL 1	3.3		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879)	1	99267916	144267916	Rat
6893361	Bw104	Body weight QTL 104	0.59	0.27	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
724567	Tcas6	Tongue tumor susceptibility QTL 6	6.85		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	1	92948896	144267916	Rat
738006	Anxrr14	Anxiety related response QTL 14	4	0.00035	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	130636910	175636910	Rat
1558645	Bw55	Body weight QTL 55	3.2	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	102813953	201278233	Rat
634348	Bp138	Blood pressure QTL 138			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	125611501	168883176	Rat
8694370	Bw154	Body weight QTL 154	8.91	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	1	103111621	148111621	Rat
738028	Anxrr12	Anxiety related response QTL 12	4.9	0.00001	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	130636910	175636910	Rat
1354623	Rf46	Renal function QTL 46	3.8		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	1	102813953	151162766	Rat
631654	Bp107	Blood pressure QTL 107			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	125611501	170611501	Rat
631544	Bp84	Blood pressure QTL 84	5.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123350408	181759564	Rat
152025212	Bw190	Body weight QTL 190	5.7		body mass (VT:0001259)		1	123556856	196963478	Rat
631549	Bp89	Blood pressure QTL 89	5.7		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123350581	201284552	Rat
1358189	Cstrr1	Cold stress response QTL 1		0.0001	catecholamine amount (VT:0010543)	urine norepinephrine level (CMO:0001629)	1	123350408	182418476	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	102813953	218753816	Rat

BE121204

Rat Assembly	Chr	Position (strand)	Source
Celera	1	126,236,930 - 126,237,090	UniSTS
RH 3.4 Map	1	1068.9	UniSTS
Cytogenetic Map	1	q31	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001170462	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105603	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105606	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC098793	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BQ199902	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB766016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO560916	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DN936852	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ210687	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000030914 ⟹ ENSRNOP00000030864

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	134,149,536 - 134,177,775 (+)	Ensembl
Rnor_6.0 Ensembl	1	141,986,145 - 142,014,398 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000108313 ⟹ ENSRNOP00000092953

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	134,160,096 - 134,177,775 (+)	Ensembl

RefSeq Acc Id:

NM_001170462 ⟹ NP_001163933

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	143,558,797 - 143,587,037 (+)	NCBI
mRatBN7.2	1	134,149,536 - 134,177,777 (+)	NCBI
Rnor_6.0	1	141,986,145 - 142,014,400 (+)	NCBI
Rnor_5.0	1	142,941,088 - 142,968,795 (+)	NCBI
RGSC_v3.4	1	136,001,219 - 136,031,302 (+)	RGD
Celera	1	126,209,674 - 126,237,909 (+)	RGD

Sequence:

show sequence

ACTCCACTTGAGCAACCTGAGCCGGAGGACGCCGCTCCTGCCGCGGTCCGAGCTCCACGCGCCGCGATGGGCCGGGCGAGCCGCTCCGCCGACCTGCTGAGCGCGCTGCAGCTGCTGTTGCTACTGCT
GCGGACGACGACGGCGCGGGCGCTCGGCCCACGGATCAGTGTGCCGCTGGACTCTGAAGAAAGGCTGATTAGAAAATTTGAAGCTGAAAACATCTCCAACTACACGGCCCTTCTGCTGAGCCAAGATG
GCAAGACGCTGTATGTGGGGGCCCGAGAGGCCCTCTTTGCCCTTAACAGCAACCTCAGCTTCTTGCCGGGCGGGGAGTACCAAGAGCTGCTGTGGAGTGCAGATCCTGACAGGAAGCAGCAGTGCAGC
TTCAAGGGCAAGGACCCAAAGCGTGACTGTCAAAACTACATCAAGATCCTTCTGCCCCTCAACAGCAGCCATCTGCTCACCTGTGGCACCGCAGCCTTCAGCCCCCTGTGTGCTTACATTAACACAGC
AAGCTTTACATTAGCCCGAGACGAGGCTGGCAGTGTCCTCCTAGAGGATGGCAAGGGCCGGTGTCCCTTTGACCCCAACTTCAAGTCCACGGCTCTGGTGGTTGATGGTGAGCTGTACACTGGAACAG
TCAGTAGCTTCCAGGGAAACGACCCAGCCATTTCCCGGAGCCAGAGTCCCCGCCCCACCAAGACTGAGAGCTCCCTCAACTGGCTGCAAGACCCTGCCTTTGTGGCCTCAGCCTATGTTCCTGAGAGC
CTGGGCAGCCCAATAGGTGATGATGATAAGATCTACTTCTTCTTCAGCGAGACGGGCCAGGAGTTTGAGTTCTTTGAGAACACCATTGTCTCCAGAGTTGCCCGAGTCTGTAAGGGCGATGAGGGTGG
AGAGCGGGTGTTGCAGCAGCGCTGGACTTCCTTCCTCAAGGCTCAGCTCCTGTGCTCCCGGCCCGATGATGGCTTTCCCTTTAACGTGCTACAAGATGTCTTCACCCTGAACCCCAACCCTCAGGACT
GGCGCAAGACCCTTTTCTATGGGGTCTTTACCTCCCAGTGGCACAGAGGGACCACAGAAGGCTCTGCCATCTGCGTCTTCACCATGAATGACGTGCAGAAGGCCTTTGATGGTCTGTATAAGAAAGTG
AACAGAGAGACACAGCAGTGGTATACTGAGACCCACCCAGTGCCCACTCCCCGGCCGGGAGCGTGTATCACCAACAGTGCCCGGGAACGGAAGATCAACTCGTCGCTGCAGCTCCCGGACCGAGTGCT
GAACTTCCTCAAGGATCACTTCTTGATGGATGGGCAGGTCCGCAGCCGCCTGCTGCTGCTCCAGCCACAAGCCCGCTACCAGCGTGTGGCCGTGCACCGAGTGCCTGGCCTGCACAGCACGTATGATG
TACTATTTCTGGGCACTGGTGATGGTCGCCTGCACAAGGCAGTGACCCTGGACTCCAGAGTGCACATCATTGAGGAGCTGCAGGTCTTCCCTCAAGGACAGCCTGTGCAGAACCTGCTCTTGGACAGC
CATGGGGGACTGTTGTATGCCTCCTCCCATTCTGGGGTAGTGCAAGTGCCCGTAGCCAACTGCAGCCTGTACCCAACCTGTGGAGACTGCCTCCTGGCTCGAGACCCTTACTGCGCCTGGAACGGCTC
CACCTGCAAGCTCCTTAGTCTCTACCAGCCTGATCTGGCCTCCAGGCCATGGATCCAGGATATTGAGGGTGCCAATACCAAGGAACTCTGCAATATTTCCTCAGCCAAGGCCCGGTCTTTTAAGCCAG
GTAAGCCATGTAAACAAGTCCAGATCCAAGCAAACACAGTGAACACCCTGGCCTGCCCACTCCTCTCAAACCTGGCTACTCGGCTCTGGCTGCACAATGGGGCTCCTGTCAATGCTTCTGCCTCCTGC
CGGGTGTTACCCAGTGGGGACCTGCTGCTGGTAGGCAGCCAGCAGGGCTTGGGGGTGTTCCAGTGTTGGTCCATAGAAGAAGGATTCCGGCAGCTGGTGGCCAGCTACTGCCCAGAGGTGAAGGAGGA
TGGAGTAATGGACCAAAATGACCAGAGTGATGGCACCCCGGTCATTATCAACACATCACGAGTGAGTGCACCTGCTGGTGGCAGGGCCAGCTGGGGTGCAGACAAGTCATACTGGAATGAATTCCTGG
TGATGTGTACTCTGTTTGGGCTTGCTGTGGTGCTTCTGGTTCTGTTCTTTCTCTACCGAAATCGGGATGGCATGAAGCTCTTCCTAAAGCAGGGCGAATGTGCCAGTGTGCACCCCAAGACTCGCCCT
GCAGTGCTCCCACCTGAGACCCGACCACTCAATGGTGTTGGCCCTCCCAGCACCCCCCTTGACCACCGAGGCTACCAGGCTCTGTCGGATAGCTCCCCAGGGCCCCGAGTCTTTACTGAGTCAGAGAA
GAGGCCACTGAGTATCCAGGACAGCTTTGTGGAGGTGTCTCCTGTGTGTCCCCGGCCCCGAGTTCGACTGGGCTCTGAGATCCGAGACTCTGTGGTATGAGAACTGACTTTAGATGTAGCCACCCTGA
CCTCAGGGGCTGTGAATGTTCAGTGGAGGTCAGCTACCTCTGCTGTCACAGAACACAACCATGGTACCCTGCCTGGGAGGCAGCTGGTATCACAGCACCAACAGCCTGGCCAGCCGGTTCCAATGTCT
GGCTGAAAAGGGCTGCCTCCAGGGGCCAGAGGGTCCCTGTCTGGATGGCAGAACTCTGCTACTTAACTGAGCCCTTTGTTTAAAACTGCAAATGTGAAGCCAGAGAGAGAGGAAGGAGAGATAGATAA
GGAAGACTGTACGGCACAGCCACTCCAATTCAGCCTGCTGGGCTCTTGGGGACTTCTCTGAAGTGGCTTTGTGAGCTGGAGTTGGGAATCCCTCCCCCACTGGACTATTCATTNTACCTTCCGCCTTA
CTCCGCTGCTGAGGCCACTGCAGAATCAGGGCCCTGCTCCAGCTTCAGCCAACCAAGGACATGTCTGTGACCGCTGACACCCCACCACCTCAGGGACTAGAGGGCTAGGCTGGCTNTGCAGCCCTCCT
CACCAGACCCTGGGCTCAGTCCCAGTTCCCAGACTTCTCCAGCCTGTATCAGGCTGTGGCCTGGAAAGCAAGGGAGTGACCCCAGGGGGCGTTGTGACAGAAGACTGTTGCCTGCTGTCCTTTTCCCA
GTTGAGGAACTGTGTCGCCACCCACCTCATCAGCCCTGTTTTCTAATTCCAACACAGACTTCTGGATCCTCCCTGTTCCCTGTCCTAGCTCACCATGCCCTTGCCCACCACTCTAAGGGATACTGACA
CTGCCCATCACGAGGACCCTGAATTTACATGGGTTTTGTATTTTTTTTAATAAGATGCACTTTACTTTCTTTTTTTTAAAAATAAAGTCCAGCAAATTATAGTTAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039105603 ⟹ XP_038961531

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	143,545,727 - 143,587,032 (+)	NCBI
mRatBN7.2	1	134,136,671 - 134,177,777 (+)	NCBI

RefSeq Acc Id:

XM_039105606 ⟹ XP_038961534

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	143,545,901 - 143,584,774 (+)	NCBI
mRatBN7.2	1	134,136,646 - 134,175,512 (+)	NCBI


Protein RefSeqs	NP_001163933	(Get FASTA)	NCBI Sequence Viewer
	XP_038961531	(Get FASTA)	NCBI Sequence Viewer
	XP_038961534	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH98793	(Get FASTA)	NCBI Sequence Viewer
	EDM08612	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000030864
	ENSRNOP00000030864.6
	ENSRNOP00000092953.1
	ENSRNOP00000104021

RefSeq Acc Id:	NP_001163933 ⟸ NM_001170462
- Peptide Label:	precursor
- UniProtKB:	F1LSV0 (UniProtKB/TrEMBL), A6JC85 (UniProtKB/TrEMBL), A0A8I6AWC2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGRASRSADLLSALQLLLLLLRTTTARALGPRISVPLDSEERLIRKFEAENISNYTALLLSQDGKTLYVGAREALFALNSNLSFLPGGEYQELLWSADPDRKQQCSFKGKDPKRDCQNYIKILLPLNS SHLLTCGTAAFSPLCAYINTASFTLARDEAGSVLLEDGKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSPRPTKTESSLNWLQDPAFVASAYVPESLGSPIGDDDKIYFFFSETGQEF EFFENTIVSRVARVCKGDEGGERVLQQRWTSFLKAQLLCSRPDDGFPFNVLQDVFTLNPNPQDWRKTLFYGVFTSQWHRGTTEGSAICVFTMNDVQKAFDGLYKKVNRETQQWYTETHPVPTPRPGAC ITNSARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRLLLLQPQARYQRVAVHRVPGLHSTYDVLFLGTGDGRLHKAVTLDSRVHIIEELQVFPQGQPVQNLLLDSHGGLLYASSHSGVVQVPVANCS LYPTCGDCLLARDPYCAWNGSTCKLLSLYQPDLASRPWIQDIEGANTKELCNISSAKARSFKPGKPCKQVQIQANTVNTLACPLLSNLATRLWLHNGAPVNASASCRVLPSGDLLLVGSQQGLGVFQC WSIEEGFRQLVASYCPEVKEDGVMDQNDQSDGTPVIINTSRVSAPAGGRASWGADKSYWNEFLVMCTLFGLAVVLLVLFFLYRNRDGMKLFLKQGECASVHPKTRPAVLPPETRPLNGVGPPSTPLDH RGYQALSDSSPGPRVFTESEKRPLSIQDSFVEVSPVCPRPRVRLGSEIRDSVV hide sequence

Ensembl Acc Id:

ENSRNOP00000030864 ⟸ ENSRNOT00000030914

RefSeq Acc Id:	XP_038961534 ⟸ XM_039105606
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038961531 ⟸ XM_039105603
- Peptide Label:	isoform X1
- UniProtKB:	F1LSV0 (UniProtKB/TrEMBL), A6JC85 (UniProtKB/TrEMBL), A0A8I6AWC2 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000092953 ⟸ ENSRNOT00000108313

Protein Domains

Sema

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LSV0-F1-model_v2	AlphaFold	F1LSV0	1-819	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13690138

Promoter ID:

EPDNEW_R662

Type:

multiple initiation site

Name:

Sema4b_1

Description:

semaphorin 4B

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	141,986,145 - 141,986,205	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-58756	BioCyc
Ensembl Genes	ENSRNOG00000025167	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000030914	ENTREZGENE
	ENSRNOT00000030914.7	UniProtKB/TrEMBL
	ENSRNOT00000108313.1	UniProtKB/TrEMBL
	ENSRNOT00000171530	ENTREZGENE
Gene3D-CATH	2.130.10.10	UniProtKB/TrEMBL
	ligand-binding face of the semaphorins, domain 2	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7375669	IMAGE-MGC_LOAD
InterPro	Plexin-like_fold	UniProtKB/TrEMBL
	Plexin_repeat	UniProtKB/TrEMBL
	Semap_dom_sf	UniProtKB/TrEMBL
	Semaphorin	UniProtKB/TrEMBL
	Semaphorin/CD100_Ag	UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom	UniProtKB/TrEMBL
KEGG Report	rno:293042	UniProtKB/TrEMBL
MGC_CLONE	MGC:112834	IMAGE-MGC_LOAD
NCBI Gene	293042	ENTREZGENE
PANTHER	PTHR11036	UniProtKB/TrEMBL
	SEMAPHORIN-4B	UniProtKB/TrEMBL
Pfam	PSI	UniProtKB/TrEMBL
	Sema	UniProtKB/TrEMBL
PhenoGen	Sema4b	PhenoGen
PROSITE	SEMA	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000025167	RatGTEx
SMART	PSI	UniProtKB/TrEMBL
	Sema	UniProtKB/TrEMBL
Superfamily-SCOP	Plexin repeat	UniProtKB/TrEMBL
	Sema	UniProtKB/TrEMBL
UniProt	A0A8I6AWC2	ENTREZGENE, UniProtKB/TrEMBL
	A6JC85	ENTREZGENE, UniProtKB/TrEMBL
	F1LSV0	ENTREZGENE, UniProtKB/TrEMBL
	Q4KM50_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-01-21	Sema4b	semaphorin 4B	Sema4b	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Sema4b	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B	Sema4b_predicted	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Sema4b_predicted	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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