Drc4 (dynein regulatory complex subunit 4) - Rat Genome Database

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Gene: Drc4 (dynein regulatory complex subunit 4) Rattus norvegicus
Analyze
Symbol: Drc4 (Ensembl: Gas8)
Name: dynein regulatory complex subunit 4 (Ensembl:growth arrest specific 8)
RGD ID: 1307817
Description: Predicted to enable microtubule binding activity and small GTPase binding activity. Predicted to be involved in several processes, including flagellated sperm motility; positive regulation of protein localization to cilium; and positive regulation of smoothened signaling pathway. Predicted to act upstream of or within several processes, including brain development; determination of left/right symmetry; and epithelial cilium movement involved in extracellular fluid movement. Predicted to be located in cytoskeleton; glial cell projection; and sperm flagellum. Predicted to be active in Golgi apparatus and microtubule. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 33. Orthologous to human GAS8 (growth arrest specific 8); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GAS-11; GAS-8; Gas8; growth arrest specific 8; growth arrest-specific protein 11; growth arrest-specific protein 8; LOC361438; MGC124779
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81968,461,280 - 68,480,810 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1968,461,304 - 68,480,806 (+)EnsemblGRCr8
mRatBN7.21951,552,770 - 51,572,323 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1951,552,816 - 51,572,305 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1958,351,220 - 58,370,726 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01959,025,183 - 59,044,617 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01961,249,809 - 61,269,317 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01956,316,367 - 56,335,873 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1956,316,268 - 56,335,870 (+)Ensemblrn6Rnor6.0
Rnor_5.01967,025,533 - 67,045,034 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41953,838,508 - 53,852,302 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1950,784,247 - 50,803,673 (+)NCBICelera
RGSC_v3.11953,845,757 - 53,862,677 (+)NCBI
Cytogenetic Map19q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
9+2 motile cilium  (ISO)
axoneme  (IEA,ISO,ISS)
ciliary basal body  (IBA,ISO,ISS)
cilium  (IEA,ISO,ISS)
cytoplasm  (IEA,ISO,ISS)
cytoskeleton  (IEA)
extracellular region  (IEA)
Golgi apparatus  (IBA,IEA,ISO)
microtubule  (IBA,IEA,ISO)
microtubule cytoskeleton  (ISO,ISS)
motile cilium  (IEA,ISO,ISS)
plasma membrane  (ISO)
sperm end piece  (ISO)
sperm flagellum  (IBA,ISO,ISS)
sperm midpiece  (ISO)
sperm principal piece  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10969087   PMID:11751847   PMID:12477932   PMID:16643277   PMID:17366626   PMID:18396146   PMID:21659505   PMID:26387594   PMID:27120127   PMID:27472056   PMID:29317443  


Genomics

Comparative Map Data
Drc4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81968,461,280 - 68,480,810 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1968,461,304 - 68,480,806 (+)EnsemblGRCr8
mRatBN7.21951,552,770 - 51,572,323 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1951,552,816 - 51,572,305 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1958,351,220 - 58,370,726 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01959,025,183 - 59,044,617 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01961,249,809 - 61,269,317 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01956,316,367 - 56,335,873 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1956,316,268 - 56,335,870 (+)Ensemblrn6Rnor6.0
Rnor_5.01967,025,533 - 67,045,034 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41953,838,508 - 53,852,302 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1950,784,247 - 50,803,673 (+)NCBICelera
RGSC_v3.11953,845,757 - 53,862,677 (+)NCBI
Cytogenetic Map19q12NCBI
DRC4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381690,019,633 - 90,044,960 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1690,019,629 - 90,044,975 (+)Ensemblhg38GRCh38
GRCh371690,086,041 - 90,111,368 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361688,616,509 - 88,638,880 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341688,616,508 - 88,638,880NCBI
Celera1675,152,846 - 75,175,909 (+)NCBICelera
Cytogenetic Map16q24.3NCBI
HuRef1675,780,971 - 75,803,087 (+)NCBIHuRef
CHM1_11691,500,795 - 91,523,162 (+)NCBICHM1_1
T2T-CHM13v2.01696,105,808 - 96,131,173 (+)NCBIT2T-CHM13v2.0
Gas8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398124,245,630 - 124,263,394 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8124,245,573 - 124,263,389 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm388123,518,835 - 123,536,657 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8123,518,834 - 123,536,650 (+)Ensemblmm10GRCm38
MGSCv378126,042,735 - 126,060,550 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368126,404,925 - 126,422,740 (+)NCBIMGSCv36mm8
Celera8127,758,666 - 127,777,359 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map872.1NCBI
Gas8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555413,476,451 - 3,496,572 (+)Ensembl
ChiLan1.0NW_0049555413,477,067 - 3,494,991 (+)NCBIChiLan1.0ChiLan1.0
GAS8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21899,866,451 - 99,895,651 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116105,754,148 - 105,781,531 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01670,777,446 - 70,806,437 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11690,441,096 - 90,469,533 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1690,444,141 - 90,467,849 (+)EnsemblpanPan2panpan1.1
GAS8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1563,589,196 - 63,609,014 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl563,573,941 - 63,619,476 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha563,601,193 - 63,622,312 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0563,816,046 - 63,837,239 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl563,817,448 - 63,837,160 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1563,836,478 - 63,857,592 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0563,675,685 - 63,695,315 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0564,080,348 - 64,101,462 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101960318
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934924,337,994 - 24,355,538 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493664191,497 - 109,012 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493664192,893 - 109,006 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GAS8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl664,714 - 105,993 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1686,817 - 105,987 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26181,968 - 198,141 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DRC4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1575,353,493 - 75,370,012 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl575,354,117 - 75,371,796 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604742,425 - 74,415 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gas8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474629,776 - 44,741 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474629,776 - 44,825 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Gas8
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11743,117,806 - 43,131,218 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:36
Count of miRNA genes:35
Interacting mature miRNAs:36
Transcripts:ENSRNOT00000029999
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)196124916174246245Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat

Markers in Region
BE106712  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21951,572,085 - 51,572,242 (+)MAPPERmRatBN7.2
Rnor_6.01956,335,636 - 56,335,792NCBIRnor6.0
Rnor_5.01967,044,797 - 67,044,953UniSTSRnor5.0
Celera1950,803,439 - 50,803,595UniSTS
RH 3.4 Map19714.0UniSTS
Cytogenetic Map19q12UniSTS
AA943006  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21951,570,928 - 51,571,100 (+)MAPPERmRatBN7.2
Rnor_6.01956,334,479 - 56,334,650NCBIRnor6.0
Rnor_5.01967,043,640 - 67,043,811UniSTSRnor5.0
RGSC_v3.41953,856,916 - 53,857,087UniSTSRGSC3.4
Celera1950,802,282 - 50,802,453UniSTS
RH 3.4 Map19710.91UniSTS
Cytogenetic Map19q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 160 91 90 59 81 59 6 345 181 11 139 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000029999   ⟹   ENSRNOP00000031180
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1968,461,379 - 68,480,806 (+)Ensembl
mRatBN7.2 Ensembl1951,552,816 - 51,572,305 (+)Ensembl
Rnor_6.0 Ensembl1956,316,268 - 56,335,870 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101403   ⟹   ENSRNOP00000084663
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1968,461,304 - 68,479,629 (+)Ensembl
mRatBN7.2 Ensembl1951,552,816 - 51,570,913 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000123640   ⟹   ENSRNOP00000103862
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1968,464,014 - 68,478,907 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000132851   ⟹   ENSRNOP00000112125
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1968,467,608 - 68,479,629 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000151378   ⟹   ENSRNOP00000107041
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1968,463,736 - 68,480,806 (+)Ensembl
RefSeq Acc Id: NM_001039030   ⟹   NP_001034119
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,461,381 - 68,480,807 (+)NCBI
mRatBN7.21951,552,894 - 51,572,320 (+)NCBI
Rnor_6.01956,316,444 - 56,335,870 (+)NCBI
Rnor_5.01967,025,533 - 67,045,034 (+)NCBI
RGSC_v3.41953,838,508 - 53,852,302 (+)RGD
Celera1950,784,247 - 50,803,673 (+)RGD
Sequence:
RefSeq Acc Id: XM_006255779   ⟹   XP_006255841
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,461,280 - 68,474,412 (+)NCBI
mRatBN7.21951,552,770 - 51,565,646 (+)NCBI
Rnor_6.01956,316,367 - 56,329,174 (+)NCBI
Rnor_5.01967,025,533 - 67,045,034 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772635   ⟹   XP_008770857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,468,924 - 68,480,810 (+)NCBI
mRatBN7.21951,560,435 - 51,572,323 (+)NCBI
Rnor_6.01956,324,035 - 56,335,873 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772636   ⟹   XP_008770858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,468,929 - 68,480,810 (+)NCBI
mRatBN7.21951,552,821 - 51,572,323 (+)NCBI
Rnor_6.01956,324,040 - 56,335,873 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772637   ⟹   XP_008770859
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,468,924 - 68,480,810 (+)NCBI
mRatBN7.21951,560,435 - 51,572,323 (+)NCBI
Rnor_6.01956,324,035 - 56,335,873 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039097896   ⟹   XP_038953824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,461,280 - 68,479,630 (+)NCBI
mRatBN7.21951,552,770 - 51,571,621 (+)NCBI
RefSeq Acc Id: XM_039097897   ⟹   XP_038953825
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,468,929 - 68,480,810 (+)NCBI
mRatBN7.21951,560,440 - 51,572,323 (+)NCBI
RefSeq Acc Id: XM_039097898   ⟹   XP_038953826
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,468,929 - 68,480,810 (+)NCBI
mRatBN7.21951,560,440 - 51,572,323 (+)NCBI
RefSeq Acc Id: XM_063278166   ⟹   XP_063134236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,464,027 - 68,480,810 (+)NCBI
RefSeq Acc Id: NP_001034119   ⟸   NM_001039030
- UniProtKB: Q499U4 (UniProtKB/Swiss-Prot),   A6IZY9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255841   ⟸   XM_006255779
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008770857   ⟸   XM_008772635
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008770859   ⟸   XM_008772637
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_008770858   ⟸   XM_008772636
- Peptide Label: isoform X5
- Sequence:
Ensembl Acc Id: ENSRNOP00000031180   ⟸   ENSRNOT00000029999
RefSeq Acc Id: XP_038953824   ⟸   XM_039097896
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZZT3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038953825   ⟸   XM_039097897
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038953826   ⟸   XM_039097898
- Peptide Label: isoform X6
Ensembl Acc Id: ENSRNOP00000084663   ⟸   ENSRNOT00000101403
RefSeq Acc Id: XP_063134236   ⟸   XM_063278166
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000112125   ⟸   ENSRNOT00000132851
Ensembl Acc Id: ENSRNOP00000107041   ⟸   ENSRNOT00000151378
Ensembl Acc Id: ENSRNOP00000103862   ⟸   ENSRNOT00000123640
Protein Domains
Growth arrest-specific protein

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q499U4-F1-model_v2 AlphaFold Q499U4 1-478 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307817 AgrOrtholog
BioCyc Gene G2FUF-5320 BioCyc
Ensembl Genes ENSRNOG00000026964 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000029999 ENTREZGENE
  ENSRNOT00000029999.7 UniProtKB/Swiss-Prot
  ENSRNOT00000101403 ENTREZGENE
  ENSRNOT00000151378 ENTREZGENE
IMAGE_CLONE IMAGE:7929646 IMAGE-MGC_LOAD
InterPro GAS8 UniProtKB/Swiss-Prot
  GAS8_dom UniProtKB/Swiss-Prot
KEGG Report rno:361438 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124779 IMAGE-MGC_LOAD
NCBI Gene 361438 ENTREZGENE
PANTHER DYNEIN REGULATORY COMPLEX SUBUNIT 4 UniProtKB/Swiss-Prot
  PTHR31543 UniProtKB/Swiss-Prot
Pfam GAS UniProtKB/Swiss-Prot
PhenoGen Drc4 PhenoGen
RatGTEx ENSRNOG00000026964 RatGTEx
UniProt A0A8I5ZZT3 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L9D2_RAT UniProtKB/TrEMBL
  A0ABK0LEU7_RAT UniProtKB/TrEMBL
  A0ABK0M7W5_RAT UniProtKB/TrEMBL
  A6IZY9 ENTREZGENE, UniProtKB/TrEMBL
  DRC4_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-11-13 Drc4  dynein regulatory complex subunit 4  Gas8  growth arrest specific 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Gas8  growth arrest specific 8  Gas8_predicted  growth arrest specific 8 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Gas8_predicted  growth arrest specific 8 (predicted)      Symbol and Name status set to approved 70820 APPROVED