Rassf4 (Ras association domain family member 4) - Rat Genome Database

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Gene: Rassf4 (Ras association domain family member 4) Rattus norvegicus
Analyze
Symbol: Rassf4
Name: Ras association domain family member 4
RGD ID: 1307785
Description: Predicted to be involved in signal transduction. Orthologous to human RASSF4 (Ras association domain family member 4); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362423; MGC105606; Ras association (RalGDS/AF-6) domain family 4; Ras association (RalGDS/AF-6) domain family member 4; ras association domain-containing protein 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84151,569,984 - 151,605,203 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4151,569,984 - 151,604,883 (-)EnsemblGRCr8
mRatBN7.24149,897,525 - 149,932,658 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4149,897,543 - 149,932,411 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4156,139,459 - 156,174,177 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04151,923,501 - 151,958,219 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04150,546,393 - 150,581,114 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04148,769,092 - 148,804,295 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4148,769,096 - 148,803,988 (-)Ensemblrn6Rnor6.0
Rnor_5.04214,707,827 - 214,742,395 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44152,987,396 - 153,021,524 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4138,773,097 - 138,808,461 (-)NCBICelera
RGSC_v3.14153,232,236 - 153,266,365 (-)NCBI
Cytogenetic Map4q42NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-demecolcine  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP,ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
amphetamine  (EXP)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bilirubin IXalpha  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
Butylbenzyl phthalate  (EXP)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
diethyl phthalate  (EXP)
diethylstilbestrol  (EXP)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP)
dimethyl sulfoxide  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
gardiquimod  (ISO)
glucose  (ISO)
glycidol  (EXP)
glyphosate  (ISO)
GSK-J4  (ISO)
hydrogen cyanide  (ISO)
hydrogen peroxide  (ISO)
hypochlorous acid  (ISO)
indometacin  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosodimethylamine  (EXP)
naled  (ISO)
nickel atom  (ISO)
Nutlin-3  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
potassium cyanide  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propanal  (ISO)
propiconazole  (ISO)
protein kinase inhibitor  (ISO)
resveratrol  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
succimer  (ISO)
sunitinib  (ISO)
T-2 toxin  (EXP)
tetraphene  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (EXP,ISO)
trichostatin A  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334  


Genomics

Comparative Map Data
Rassf4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84151,569,984 - 151,605,203 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4151,569,984 - 151,604,883 (-)EnsemblGRCr8
mRatBN7.24149,897,525 - 149,932,658 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4149,897,543 - 149,932,411 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4156,139,459 - 156,174,177 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04151,923,501 - 151,958,219 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04150,546,393 - 150,581,114 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04148,769,092 - 148,804,295 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4148,769,096 - 148,803,988 (-)Ensemblrn6Rnor6.0
Rnor_5.04214,707,827 - 214,742,395 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44152,987,396 - 153,021,524 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4138,773,097 - 138,808,461 (-)NCBICelera
RGSC_v3.14153,232,236 - 153,266,365 (-)NCBI
Cytogenetic Map4q42NCBI
RASSF4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381044,959,802 - 44,995,891 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1044,959,407 - 44,995,891 (+)Ensemblhg38GRCh38
GRCh371045,455,250 - 45,491,339 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361044,775,225 - 44,810,178 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1041,458,395 - 41,493,346 (+)NCBICelera
Cytogenetic Map10q11.21NCBI
HuRef1041,979,838 - 42,015,546 (+)NCBIHuRef
CHM1_11045,494,198 - 45,529,149 (+)NCBICHM1_1
T2T-CHM13v2.01045,840,766 - 45,876,855 (+)NCBIT2T-CHM13v2.0
Rassf4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396116,609,969 - 116,650,797 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6116,609,969 - 116,650,913 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm386116,633,008 - 116,673,836 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6116,633,008 - 116,673,952 (-)Ensemblmm10GRCm38
MGSCv376116,583,026 - 116,623,854 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366116,598,627 - 116,639,410 (-)NCBIMGSCv36mm8
Celera6118,473,009 - 118,515,414 (-)NCBICelera
Cytogenetic Map6E3NCBI
cM Map653.83NCBI
Rassf4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555462,277,412 - 2,307,877 (+)Ensembl
ChiLan1.0NW_0049555462,277,679 - 2,307,877 (+)NCBIChiLan1.0ChiLan1.0
RASSF4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2857,694,441 - 57,729,424 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11057,699,779 - 57,734,753 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01041,954,378 - 41,989,334 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11045,134,004 - 45,168,949 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1045,134,004 - 45,168,949 (+)EnsemblpanPan2panpan1.1
RASSF4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1282,450,935 - 2,473,461 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl282,452,175 - 2,482,880 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha282,686,338 - 2,718,305 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0282,629,803 - 2,661,762 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl282,627,785 - 2,661,735 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1282,428,369 - 2,460,336 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0282,465,643 - 2,497,621 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0282,596,808 - 2,628,796 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rassf4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721382,022,044 - 82,061,426 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366174,722,597 - 4,761,472 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366174,722,574 - 4,761,472 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RASSF4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1491,103,526 - 91,125,360 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11491,103,518 - 91,138,501 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21499,566,741 - 99,612,051 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RASSF4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1940,584,187 - 40,619,479 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl940,584,200 - 40,619,478 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605645,784,765 - 45,819,902 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rassf4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1629,934,927 - 29,969,104 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rassf4
185 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:187
Count of miRNA genes:137
Interacting mature miRNAs:162
Transcripts:ENSRNOT00000018101
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4107346299152346299Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4134095016179095016Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4149763204169799698Rat
61446Coreg2Compensatory renal growth QTL 23.5kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)4150095743159267220Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4117737142152833657Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
1358364Sradr4Stress Responsive Adrenal Weight QTL 44.92adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)4131384565176384565Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4123870974168870974Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4140059299181024663Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4117559384162559384Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4111383604156383604Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4108206096153206096Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4106848959168870974Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4127263297172263297Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4126334185171334185Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4111383604156383604Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482944895154403548Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4124700988169700988Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4137447185182447185Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4137430611182430611Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4134199006168870974Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4148121375176967367Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4116184844161184844Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4148834094168870974Rat

Markers in Region
RH129280  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr84151,570,023 - 151,570,223 (+)Marker Load Pipeline
mRatBN7.24149,897,578 - 149,897,778 (+)MAPPERmRatBN7.2
Rnor_6.04148,769,132 - 148,769,331NCBIRnor6.0
Rnor_5.04214,707,867 - 214,708,066UniSTSRnor5.0
RGSC_v3.44152,987,436 - 152,987,635UniSTSRGSC3.4
Celera4138,773,137 - 138,773,336UniSTS
RH 3.4 Map4968.82UniSTS
Cytogenetic Map4q42UniSTS
RH141008  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24149,912,572 - 149,912,792 (+)MAPPERmRatBN7.2
Rnor_6.04148,784,126 - 148,784,345NCBIRnor6.0
Rnor_5.04214,722,861 - 214,723,080UniSTSRnor5.0
RGSC_v3.44153,002,125 - 153,002,344UniSTSRGSC3.4
Celera4138,788,131 - 138,788,350UniSTS
RH 3.4 Map4966.6UniSTS
Cytogenetic Map4q42UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 355 192 11 144 80 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000018101   ⟹   ENSRNOP00000018101
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4151,569,984 - 151,604,883 (-)Ensembl
mRatBN7.2 Ensembl4149,897,543 - 149,932,411 (-)Ensembl
Rnor_6.0 Ensembl4148,769,096 - 148,803,988 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101033   ⟹   ENSRNOP00000077644
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4151,570,288 - 151,604,883 (-)Ensembl
mRatBN7.2 Ensembl4149,898,641 - 149,932,411 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119956   ⟹   ENSRNOP00000087510
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4149,908,782 - 149,932,411 (-)Ensembl
RefSeq Acc Id: NM_001024275   ⟹   NP_001019446
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84151,569,984 - 151,604,883 (-)NCBI
mRatBN7.24149,897,539 - 149,932,439 (-)NCBI
Rnor_6.04148,769,092 - 148,803,988 (-)NCBI
Rnor_5.04214,707,827 - 214,742,395 (-)NCBI
RGSC_v3.44152,987,396 - 153,021,524 (-)RGD
Celera4138,773,097 - 138,808,461 (-)RGD
Sequence:
RefSeq Acc Id: XM_017592701   ⟹   XP_017448190
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84151,569,984 - 151,605,203 (-)NCBI
mRatBN7.24149,897,525 - 149,932,658 (-)NCBI
Rnor_6.04148,770,462 - 148,804,295 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039107862   ⟹   XP_038963790
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84151,569,984 - 151,604,968 (-)NCBI
mRatBN7.24149,897,525 - 149,932,521 (-)NCBI
RefSeq Acc Id: XM_039107863   ⟹   XP_038963791
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84151,569,984 - 151,581,479 (-)NCBI
mRatBN7.24149,897,525 - 149,909,030 (-)NCBI
RefSeq Acc Id: NP_001019446   ⟸   NM_001024275
- UniProtKB: Q566C5 (UniProtKB/Swiss-Prot),   A6IL26 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448190   ⟸   XM_017592701
- Peptide Label: isoform X1
- UniProtKB: Q566C5 (UniProtKB/Swiss-Prot),   A6IL26 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018101   ⟸   ENSRNOT00000018101
RefSeq Acc Id: XP_038963790   ⟸   XM_039107862
- Peptide Label: isoform X2
- UniProtKB: A0A8I5YBY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963791   ⟸   XM_039107863
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000087510   ⟸   ENSRNOT00000119956
Ensembl Acc Id: ENSRNOP00000077644   ⟸   ENSRNOT00000101033
Protein Domains
Ras-associating   SARAH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q566C5-F1-model_v2 AlphaFold Q566C5 1-322 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693338
Promoter ID:EPDNEW_R3862
Type:multiple initiation site
Name:Rassf4_1
Description:Ras association domain family member 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04148,804,022 - 148,804,082EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307785 AgrOrtholog
BioCyc Gene G2FUF-43280 BioCyc
Ensembl Genes ENSRNOG00000013526 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000018101 ENTREZGENE
  ENSRNOT00000018101.8 UniProtKB/Swiss-Prot
  ENSRNOT00000101033 ENTREZGENE
Gene3D-CATH Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7315142 IMAGE-MGC_LOAD
InterPro C-RASSF UniProtKB/Swiss-Prot
  RA_dom UniProtKB/Swiss-Prot
  RASSF4 UniProtKB/Swiss-Prot
  SARAH_dom UniProtKB/Swiss-Prot
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot
KEGG Report rno:362423 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105606 IMAGE-MGC_LOAD
NCBI Gene 362423 ENTREZGENE
PANTHER PTHR22738 UniProtKB/Swiss-Prot
  PTHR22738:SF4 UniProtKB/Swiss-Prot
Pfam Nore1-SARAH UniProtKB/Swiss-Prot
  PF00788 UniProtKB/Swiss-Prot
PhenoGen Rassf4 PhenoGen
PROSITE PS50200 UniProtKB/Swiss-Prot
  SARAH UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000013526 RatGTEx
SMART SM00314 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54236 UniProtKB/Swiss-Prot
UniProt A0A8I5YBY7 ENTREZGENE, UniProtKB/TrEMBL
  A6IL26 ENTREZGENE, UniProtKB/TrEMBL
  Q566C5 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-03 Rassf4  Ras association domain family member 4  Rassf4  Ras association (RalGDS/AF-6) domain family member 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-25 Rassf4  Ras association (RalGDS/AF-6) domain family member 4  Rassf4  Ras association (RalGDS/AF-6) domain family 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Rassf4  Ras association (RalGDS/AF-6) domain family 4  Rassf4_predicted  Ras association (RalGDS/AF-6) domain family 4 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Rassf4_predicted  Ras association (RalGDS/AF-6) domain family 4 (predicted)      Symbol and Name status set to approved 70820 APPROVED