Kdsr (3-ketodihydrosphingosine reductase) - Rat Genome Database

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Gene: Kdsr (3-ketodihydrosphingosine reductase) Rattus norvegicus
Analyze
Symbol: Kdsr
Name: 3-ketodihydrosphingosine reductase
RGD ID: 1307775
Description: Predicted to enable 3-dehydrosphinganine reductase activity. Predicted to be involved in 3-keto-sphinganine metabolic process and sphingolipid biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis et progressiva 4 and follicular lymphoma. Orthologous to human KDSR (3-ketodihydrosphingosine reductase); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: follicular lymphoma variant translocation 1; Fvt1; LOC360833
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81323,374,101 - 23,408,779 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1323,376,779 - 23,408,897 (-)EnsemblGRCr8
mRatBN7.21322,862,117 - 22,894,118 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1322,862,117 - 22,894,108 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1323,184,947 - 23,216,962 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01324,469,418 - 24,501,431 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01323,155,132 - 23,187,149 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01326,779,386 - 26,812,271 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1326,780,633 - 26,812,215 (-)Ensemblrn6Rnor6.0
Rnor_5.01331,929,862 - 31,962,754 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41312,914,967 - 12,946,853 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1322,721,005 - 22,752,490 (-)NCBICelera
RGSC_v3.11312,914,896 - 12,946,797 (-)NCBI
Cytogenetic Map13p11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
all-trans-retinoic acid  (ISO)
Aroclor 1254  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
Benoxacor  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Butylbenzyl phthalate  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chloroprene  (EXP)
clofibrate  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dichloroacetic acid  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
gallic acid  (ISO)
gentamycin  (EXP)
inulin  (ISO)
levonorgestrel  (ISO)
mercury dichloride  (ISO)
N,N-diethyl-m-toluamide  (EXP)
NADP zwitterion  (ISO)
NADP(+)  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone undecanoate  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. FVT-1, a novel human transcription unit affected by variant translocation t(2;18)(p11;q21) of follicular lymphoma. Rimokh R, etal., Blood. 1993 Jan 1;81(1):136-42.
Additional References at PubMed
PMID:15328338   PMID:15364918   PMID:19946888   PMID:28575652  


Genomics

Comparative Map Data
Kdsr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81323,374,101 - 23,408,779 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1323,376,779 - 23,408,897 (-)EnsemblGRCr8
mRatBN7.21322,862,117 - 22,894,118 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1322,862,117 - 22,894,108 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1323,184,947 - 23,216,962 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01324,469,418 - 24,501,431 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01323,155,132 - 23,187,149 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01326,779,386 - 26,812,271 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1326,780,633 - 26,812,215 (-)Ensemblrn6Rnor6.0
Rnor_5.01331,929,862 - 31,962,754 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41312,914,967 - 12,946,853 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1322,721,005 - 22,752,490 (-)NCBICelera
RGSC_v3.11312,914,896 - 12,946,797 (-)NCBI
Cytogenetic Map13p11NCBI
KDSR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381863,327,726 - 63,367,206 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1863,327,566 - 63,367,615 (-)Ensemblhg38GRCh38
GRCh371860,994,959 - 61,034,439 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361859,145,951 - 59,185,486 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341859,148,812 - 59,185,438NCBI
Celera1857,714,472 - 57,754,142 (-)NCBICelera
Cytogenetic Map18q21.33NCBI
HuRef1857,693,465 - 57,733,080 (-)NCBIHuRef
CHM1_11860,990,909 - 61,030,493 (-)NCBICHM1_1
T2T-CHM13v2.01863,532,776 - 63,572,250 (-)NCBIT2T-CHM13v2.0
Kdsr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391106,648,140 - 106,689,544 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1106,648,189 - 106,687,457 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381106,720,410 - 106,759,742 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1106,720,459 - 106,759,727 (-)Ensemblmm10GRCm38
MGSCv371108,616,987 - 108,656,319 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361108,551,436 - 108,587,347 (-)NCBIMGSCv36mm8
Celera1109,569,745 - 109,609,088 (-)NCBICelera
Cytogenetic Map1E2.1NCBI
cM Map149.99NCBI
Kdsr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540247,092,779 - 47,130,132 (-)Ensembl
ChiLan1.0NW_00495540247,092,779 - 47,130,131 (-)NCBIChiLan1.0ChiLan1.0
KDSR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21780,840,824 - 80,878,698 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11866,530,449 - 66,571,494 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01856,686,914 - 56,727,681 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11860,003,576 - 60,040,365 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1860,001,637 - 60,036,292 (-)EnsemblpanPan2panpan1.1
KDSR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1113,682,838 - 13,726,872 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl113,689,246 - 13,723,528 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha114,654,928 - 14,692,956 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0113,550,434 - 13,588,484 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl113,550,483 - 13,585,739 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1113,588,547 - 13,626,566 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0113,517,813 - 13,555,882 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0113,766,595 - 13,804,675 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Kdsr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494426,931,216 - 26,960,699 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364972,169,712 - 2,203,150 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364972,169,982 - 2,199,600 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KDSR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1158,288,544 - 158,329,881 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11158,288,544 - 158,329,898 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21175,775,310 - 175,822,928 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KDSR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11816,392,714 - 16,429,912 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1816,392,756 - 16,434,035 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660609,258,194 - 9,295,466 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kdsr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247929,040,999 - 9,082,154 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247929,038,076 - 9,081,650 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Kdsr
244 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:233
Count of miRNA genes:158
Interacting mature miRNAs:198
Transcripts:ENSRNOT00000003728
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2317027Aia22Adjuvant induced arthritis QTL 222.29joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)13134785618Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131244842148744906Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)131186625456866254Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
2317034Aia9Adjuvant induced arthritis QTL 94.62joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131228551734884386Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)13308875548088755Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131244842147969993Rat
631672Iddm12Insulin dependent diabetes mellitus QTL 122.20.0032blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)13600200837088115Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
2303031Bp326Blood pressure QTL 326arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131228551723516549Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131746828262468282Rat
2303030Bp327Blood pressure QTL 327arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)13143736554Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
2317044Aia23Adjuvant induced arthritis QTL 232.3joint integrity trait (VT:0010548)ankle joint diameter (CMO:0002148)131228551734884386Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13600200847359539Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131771133662711336Rat
738036Lnnr4Liver neoplastic nodule remodeling QTL 43.64liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)13134785618Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)131186625456866254Rat

Markers in Region
BE100511  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21322,862,523 - 22,862,683 (+)MAPPERmRatBN7.2
Rnor_6.01326,779,793 - 26,779,952NCBIRnor6.0
Rnor_5.01331,930,269 - 31,930,428UniSTSRnor5.0
RGSC_v3.41312,915,374 - 12,915,533UniSTSRGSC3.4
Celera1322,721,412 - 22,721,571UniSTS
Cytogenetic Map13p13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000003728   ⟹   ENSRNOP00000003728
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1322,862,590 - 22,894,100 (-)Ensembl
Rnor_6.0 Ensembl1326,780,633 - 26,812,215 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000090097   ⟹   ENSRNOP00000073187
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1323,376,779 - 23,404,583 (-)Ensembl
mRatBN7.2 Ensembl1322,862,117 - 22,889,925 (-)Ensembl
Rnor_6.0 Ensembl1326,780,633 - 26,811,904 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099177   ⟹   ENSRNOP00000085720
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1323,376,779 - 23,408,897 (-)Ensembl
mRatBN7.2 Ensembl1322,862,117 - 22,893,189 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099271   ⟹   ENSRNOP00000093847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1323,376,779 - 23,408,765 (-)Ensembl
mRatBN7.2 Ensembl1322,862,117 - 22,894,108 (-)Ensembl
RefSeq Acc Id: NM_001108342   ⟹   NP_001101812
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81323,376,779 - 23,408,765 (-)NCBI
mRatBN7.21322,862,117 - 22,894,108 (-)NCBI
Rnor_6.01326,779,386 - 26,812,271 (-)NCBI
Rnor_5.01331,929,862 - 31,962,754 (-)NCBI
RGSC_v3.41312,914,967 - 12,946,853 (-)RGD
Celera1322,721,005 - 22,752,490 (-)RGD
Sequence:
RefSeq Acc Id: XM_039090876   ⟹   XP_038946804
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81323,374,101 - 23,408,779 (-)NCBI
mRatBN7.21322,862,577 - 22,894,118 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001101812 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946804 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL91747 (Get FASTA)   NCBI Sequence Viewer  
  EDL91748 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000073187.2
  ENSRNOP00000085720
  ENSRNOP00000085720.1
  ENSRNOP00000093847
  ENSRNOP00000093847.2
RefSeq Acc Id: NP_001101812   ⟸   NM_001108342
- UniProtKB: A0A8I6AMK1 (UniProtKB/TrEMBL),   A6JSV0 (UniProtKB/TrEMBL),   A6JSU9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073187   ⟸   ENSRNOT00000090097
Ensembl Acc Id: ENSRNOP00000003728   ⟸   ENSRNOT00000003728
RefSeq Acc Id: XP_038946804   ⟸   XM_039090876
- Peptide Label: isoform X1
- UniProtKB: D3Z9P1 (UniProtKB/TrEMBL),   A6JSU9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000093847   ⟸   ENSRNOT00000099271
Ensembl Acc Id: ENSRNOP00000085720   ⟸   ENSRNOT00000099177

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3Z9P1-F1-model_v2 AlphaFold D3Z9P1 1-332 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698749
Promoter ID:EPDNEW_R9274
Type:single initiation site
Name:Kdsr_2
Description:3-ketodihydrosphingosine reductase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R9275  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01326,811,302 - 26,811,362EPDNEW
RGD ID:13698750
Promoter ID:EPDNEW_R9275
Type:initiation region
Name:Kdsr_1
Description:3-ketodihydrosphingosine reductase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R9274  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01326,812,218 - 26,812,278EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307775 AgrOrtholog
BioCyc Gene G2FUF-18602 BioCyc
Ensembl Genes ENSRNOG00000002781 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000090097.3 UniProtKB/TrEMBL
  ENSRNOT00000099177 ENTREZGENE
  ENSRNOT00000099177.2 UniProtKB/TrEMBL
  ENSRNOT00000099271 ENTREZGENE
  ENSRNOT00000099271.2 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro Glc/ribitol_DH UniProtKB/TrEMBL
  KDSR-like UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  Sc_DH/Rdtase_CS UniProtKB/TrEMBL
KEGG Report rno:360833 UniProtKB/TrEMBL
NCBI Gene 360833 ENTREZGENE
PANTHER 3-KETODIHYDROSPHINGOSINE REDUCTASE UniProtKB/TrEMBL
  3-KETODIHYDROSPHINGOSINE REDUCTASE UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
PhenoGen Kdsr PhenoGen
PRINTS GDHRDH UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/TrEMBL
PROSITE ADH_SHORT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002781 RatGTEx
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A0G2K4V4_RAT UniProtKB/TrEMBL
  A0A8I6A295_RAT UniProtKB/TrEMBL
  A0A8I6AMK1 ENTREZGENE, UniProtKB/TrEMBL
  A6JSU9 ENTREZGENE, UniProtKB/TrEMBL
  A6JSV0 ENTREZGENE, UniProtKB/TrEMBL
  D3Z9P1 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-06-27     Kdsr  3-ketodihydrosphingosine reductase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-11 Kdsr  3-ketodihydrosphingosine reductase  Fvt1_predicted  follicular lymphoma variant translocation 1 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Fvt1_predicted  follicular lymphoma variant translocation 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED