Ttc8 (tetratricopeptide repeat domain 8)

Gene: Ttc8 (tetratricopeptide repeat domain 8) Rattus norvegicus

Analyze

Symbol:

Ttc8

Name:

tetratricopeptide repeat domain 8

RGD ID:

1307769

Description:

Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity. Predicted to be involved in establishment of anatomical structure orientation; fat cell differentiation; and non-motile cilium assembly. Predicted to act upstream of or within several processes, including morphogenesis of a polarized epithelium; multi-ciliated epithelial cell differentiation; and nervous system development. Predicted to be located in centrosome; ciliary membrane; and photoreceptor connecting cilium. Predicted to be part of BBSome. Predicted to be active in ciliary basal body and non-motile cilium. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 8; and retinitis pigmentosa 51. Orthologous to human TTC8 (tetratricopeptide repeat domain 8); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cobalt dichloride.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC299246; tetratricopeptide repeat protein 8

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TTC8 (tetratricopeptide repeat domain 8)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Ttc8 (tetratricopeptide repeat domain 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ttc8 (tetratricopeptide repeat domain 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TTC8 (tetratricopeptide repeat domain 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TTC8 (tetratricopeptide repeat domain 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ttc8 (tetratricopeptide repeat domain 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TTC8 (tetratricopeptide repeat domain 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TTC8 (tetratricopeptide repeat domain 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ttc8 (tetratricopeptide repeat domain 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	TTC8 (tetratricopeptide repeat domain 8)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ttc8 (tetratricopeptide repeat domain 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ttc8 (tetratricopeptide repeat domain 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	BBS8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	bbs-8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ttc8	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	123,927,657 - 124,025,354 (+)	NCBI		GRCr8
mRatBN7.2	6	118,198,186 - 118,252,422 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	118,198,201 - 118,252,418 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	118,348,070 - 118,402,289 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	118,644,871 - 118,699,091 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	117,979,722 - 118,033,939 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	122,920,308 - 122,974,525 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	122,920,317 - 122,974,522 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	132,140,808 - 132,207,306 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	123,117,534 - 123,171,840 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	123,121,373 - 123,174,881 (+)	NCBI
Celera	6	115,755,975 - 115,810,232 (+)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bardet-Biedl syndrome (ISO)

Bardet-Biedl syndrome 8 (ISO,ISS)

fundus dystrophy (ISO)

genetic disease (ISO)

intellectual disability (ISO)

Leber congenital amaurosis 3 (ISO)

macular degeneration (ISO)

retinal degeneration (ISO)

retinitis pigmentosa (ISO)

retinitis pigmentosa 51 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,1-dichloroethene (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4-hydroxyphenyl retinamide (ISO)

all-trans-retinoic acid (ISO)

Aroclor 1254 (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

carbon nanotube (ISO)

CGP 52608 (ISO)

clothianidin (ISO)

cobalt dichloride (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dibutyl phthalate (ISO)

doxorubicin (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

furan (EXP)

gentamycin (EXP)

lead diacetate (ISO)

manganese(II) chloride (EXP)

methyl methanesulfonate (ISO)

N,N-diethyl-m-toluamide (EXP)

N-ethyl-N-nitrosourea (ISO)

N-methyl-4-phenylpyridinium (EXP)

paracetamol (EXP,ISO)

permethrin (EXP)

pirinixic acid (ISO)

potassium chromate (ISO)

Soman (EXP)

sunitinib (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axon guidance (ISO)

biological_process (ND)

camera-type eye photoreceptor cell differentiation (ISO)

cilium assembly (ISO)

establishment of anatomical structure orientation (ISO)

establishment of epithelial cell apical/basal polarity (ISO)

establishment of planar polarity (ISO)

fat cell differentiation (ISO)

inner ear receptor cell stereocilium organization (ISO)

multi-ciliated epithelial cell differentiation (ISO)

multicellular organism growth (ISO)

non-motile cilium assembly (IBA)

olfactory bulb development (ISO)

protein localization to plasma membrane (ISO)

regulation of protein localization (ISO)

regulation of stress fiber assembly (ISO)

renal tubule development (ISO)

sensory perception of smell (ISO)

Cellular Component

BBSome (IBA,ISO)

centrosome (ISO)

ciliary basal body (IBA,ISO)

ciliary membrane (ISO)

cilium (ISO)

membrane (ISO)

non-motile cilium (IBA)

photoreceptor connecting cilium (ISO)

Molecular Function

protein binding (ISO)

RNA polymerase II-specific DNA-binding transcription factor binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome.	Ansley SJ, etal., Nature. 2003 Oct 9;425(6958):628-33. Epub 2003 Sep 21.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:12477932	PMID:17379567	PMID:17574030	PMID:20080638	PMID:21646512	PMID:22072986	PMID:22139371	PMID:22302990	PMID:22479622	PMID:22500027	PMID:23716571	PMID:24550735
PMID:25243405	PMID:25605782	PMID:27684375

Genomics

Comparative Map Data

Ttc8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	123,927,657 - 124,025,354 (+)	NCBI		GRCr8
mRatBN7.2	6	118,198,186 - 118,252,422 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	118,198,201 - 118,252,418 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	118,348,070 - 118,402,289 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	118,644,871 - 118,699,091 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	117,979,722 - 118,033,939 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	122,920,308 - 122,974,525 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	122,920,317 - 122,974,522 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	132,140,808 - 132,207,306 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	123,117,534 - 123,171,840 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	123,121,373 - 123,174,881 (+)	NCBI
Celera	6	115,755,975 - 115,810,232 (+)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

TTC8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	88,824,153 - 88,881,079 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	88,824,153 - 88,881,078 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	89,290,497 - 89,347,423 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	88,360,731 - 88,414,088 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	88,360,730 - 88,414,087	NCBI
Celera	14	69,339,325 - 69,392,681 (+)	NCBI		Celera
Cytogenetic Map	14	q31.3	NCBI
HuRef	14	69,465,840 - 69,519,171 (+)	NCBI		HuRef
CHM1_1	14	89,228,786 - 89,282,145 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	83,047,758 - 83,104,682 (+)	NCBI		T2T-CHM13v2.0

Ttc8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	98,886,796 - 98,949,509 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	98,886,833 - 98,949,497 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	98,920,537 - 98,983,250 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	98,920,574 - 98,983,238 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	100,158,784 - 100,221,448 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	99,321,639 - 99,384,288 (+)	NCBI		MGSCv36	mm8
Celera	12	100,146,253 - 100,210,179 (+)	NCBI		Celera
Cytogenetic Map	12	E	NCBI
cM Map	12	49.88	NCBI

Ttc8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955438	11,409,982 - 11,466,523 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955438	11,410,196 - 11,466,044 (+)	NCBI	ChiLan1.0	ChiLan1.0

TTC8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	89,967,618 - 90,027,137 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	89,187,209 - 89,243,644 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	69,446,355 - 69,502,351 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	88,802,812 - 88,857,055 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	88,802,812 - 88,857,055 (+)	Ensembl	panpan1.1		panPan2

TTC8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	60,061,670 - 60,115,464 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	60,061,732 - 60,115,075 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	59,641,066 - 59,693,906 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	60,332,658 - 60,386,187 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	60,332,402 - 60,386,190 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	60,013,742 - 60,066,541 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	60,063,485 - 60,116,262 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	60,391,356 - 60,444,177 (+)	NCBI		UU_Cfam_GSD_1.0

Ttc8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	15,762,381 - 15,810,727 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936488	16,258,058 - 16,306,589 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936488	16,258,247 - 16,306,077 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TTC8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	110,731,731 - 110,784,853 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	110,731,729 - 110,783,999 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	117,222,186 - 117,274,088 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TTC8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	66,483,808 - 66,539,717 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	66,483,864 - 66,539,142 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	53,829,890 - 53,884,739 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ttc8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	13,437,221 - 13,497,510 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	13,437,234 - 13,497,269 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ttc8
215 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	11
Count of miRNA genes:	11
Interacting mature miRNAs:	11
Transcripts:	ENSRNOT00000068595
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
731173	Uae22	Urinary albumin excretion QTL 22	10.1		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
2290393	Uae37	Urinary albumin excretion QTL 37		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	72202632	130729475	Rat
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	72202632	130919985	Rat
1581550	Pur8	Proteinuria QTL 8			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	72227641	130729205	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	72227641	130729205	Rat
738034	Anxrr5	Anxiety related response QTL 5	5.9		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	6	84130881	129130881	Rat
10054138	Gmadr3	Adrenal mass QTL 3	3.68	0.00045	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	6	85140138	130140138	Rat
10054123	Srcrt6	Stress Responsive Cort QTL 6	2.5	0.0043	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	85140138	130140138	Rat
724513	Uae14	Urinary albumin excretion QTL 14	6.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	85311061	133478515	Rat
1300076	Glom8	Glomerulus QTL 8	7	0.000000009	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	6	86894788	131894788	Rat
2303624	Vencon5	Ventilatory control QTL 5	4.45		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	6	88047916	133047916	Rat
1331725	Bp212	Blood pressure QTL 212	3.52475		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	93701310	128713626	Rat
61414	Pia3	Pristane induced arthritis QTL 3	4.5		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	6	94968928	137848904	Rat
12801411	Schws8	Schwannoma susceptibility QTL 8			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	94968928	139968928	Rat
8552796	Vie3	Viral induced encephalitis QTL 3	2.6		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	6	96833997	140994061	Rat
1358355	Srcrt4	Stress Responsive Cort QTL 4	6.39		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	100364669	140994061	Rat
2313399	Anxrr28	Anxiety related response QTL 28			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	6	100671796	132340886	Rat
1331797	Bp213	Blood pressure QTL 213	3.291		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	104085867	128713626	Rat
71111	Iddm8	Insulin dependent diabetes mellitus QTL 8	1.9	0.002	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	6	105156861	140994061	Rat
4145118	Mcs26	Mammary carcinoma susceptibility QTL 26		0.0001	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	6	106752656	132339866	Rat
737976	Pia24	Pristane induced arthritis QTL 24			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	6	112636280	140994061	Rat
1298087	Iddm18	Insulin dependent diabetes mellitus QTL 18		0.0001	urine glucose amount (VT:0001758)	percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)	6	116506292	130245370	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		4	11	4		4			67	23	37
Low	3	39	46	37	19	37	8	10	7	12	4	11	8
Below cutoff								1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106752	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399497	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399499	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006240424	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112067	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112069	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261759	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261760	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261761	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010052074	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010052075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC117104	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC161880	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473982	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218320	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218321	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218322	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218323	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218324	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218325	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218326	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218327	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218328	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218329	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218330	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218331	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218332	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218333	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218334	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218335	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218336	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218337	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218338	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218339	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218340	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218341	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218342	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218343	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218344	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218345	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218346	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218347	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218348	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218350	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218351	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218352	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218355	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218356	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218357	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218358	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218359	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218360	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX218361	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000068595 ⟹ ENSRNOP00000060304

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	118,198,201 - 118,252,415 (+)	Ensembl
Rnor_6.0 Ensembl	6	122,920,317 - 122,974,522 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000082856 ⟹ ENSRNOP00000068618

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	118,198,211 - 118,252,418 (+)	Ensembl
Rnor_6.0 Ensembl	6	122,920,339 - 122,974,519 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000094428 ⟹ ENSRNOP00000085100

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	118,198,255 - 118,252,270 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000094918 ⟹ ENSRNOP00000096518

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	118,198,201 - 118,217,368 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000097062 ⟹ ENSRNOP00000093561

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	118,214,467 - 118,252,270 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000102593 ⟹ ENSRNOP00000083411

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	118,199,380 - 118,252,270 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000107635 ⟹ ENSRNOP00000085312

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	118,198,201 - 118,232,325 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000114010 ⟹ ENSRNOP00000097577

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	118,212,002 - 118,252,418 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000114433 ⟹ ENSRNOP00000088851

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	118,198,255 - 118,252,270 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000118948 ⟹ ENSRNOP00000077009

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	118,198,211 - 118,252,418 (+)	Ensembl

RefSeq Acc Id:

NM_001106752 ⟹ NP_001100222

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,927,907 - 123,982,114 (+)	NCBI
mRatBN7.2	6	118,198,201 - 118,252,415 (+)	NCBI
Rnor_6.0	6	122,920,317 - 122,974,522 (+)	NCBI
Rnor_5.0	6	132,140,808 - 132,207,306 (+)	NCBI
RGSC_v3.4	6	123,117,534 - 123,171,840 (+)	RGD
Celera	6	115,755,975 - 115,810,232 (+)	RGD

Sequence:

show sequence

GACGCCTCCCGCTCTCAGCTCCCGGACCCCGCCCACCCCAGGCCGGGTTCTGGGCACAGGACCT
TTGAGCTCGTTGAGCGCTCTCCCGGACCACCATGGGCTCAGAGATGGAGCCACTGTTCCGGGCC
TGGAGCTATTTTAGACGCAGGAAGTTCCAGCTCTGCGCCGATCTATGCACGCAGATGCTGGAGA
AGTCCCCTTATGACCAGGCGGCTTGGATTTTGAAAGCGCGAGCGCTGACAGAAATGGTGTACGT
AGATGAAATTGACGTGGACCAGGAAGGGATTGCTGAGATGACCCTGGATGAAAATGCTATTGCT
CAGGTCCCACGCCCTGGCACATCTTTGAAGCTCCCTGGCACTAACCAGACAGGAGGACCGACTC
AAGCTGTCAGGCCAATCACTCAAGCTGGAAGACCCATAACGGGCTTCCTTAGGCCCAGCACACA
GAGTGGAAGACCGGGTACAATGGAGCAGGCCATCAGAACACCCAGAACGGCCTACACAGCACGA
CCTATCACCAGCTCATCTGGAAGATTCGTCAGACTGGGGACTGCTTTATTTGAATATATTTTCC
ACCATGAAAACGATGTTAAGATGAAGCAAATCATAATTGAGAATGAATTGTTTTCAAAGGCTTT
GGACTTGGCGTCCCTTTCCACGGAGTATTCTCAGTACAAGGACTGGTGGTGGAAGGTGCAGATT
GGAAAATGTTACTACAGGTTAGGAATGTACCGTGAAGCAGAGAAACAGTTCAAATCAGCCCTGA
AGCAGCAGGAAATGGTAGATACATTTCTCTATCTGGCAAAAGTTTATATCATATTGGATCAACC
TGTGACTGCTTTAAATCTATTCAAACAAGGCTTAGATAAGTTTCCAGGAGAGGTGACCCTGCTT
TGTGGAATTGCCAGGATCTACGAGGAAATGAACAACAGTTCGTCCGCAGCAGAATACTACAAAG
AGGTTCTCAAACAAGACAATACTCATGTGGAAGCCATTGCCTGCATTGGAAGCAACCACTTTTA
TTCTGACCAGCCAGAGGTTGCCCTCCGGTTTTACAGGCGCCTCTTGCAGATGGGAGTTTACAAC
TGCCAGCTTTTCAACAACCTGGGGCTGTGCTGCTTCTATGCCCAGCAGTACGACATGACTCTGA
CCTCATTCGAGCGCGCCCTTTCCCTGGCCGAGAACGAGGAAGAGGCAGCTGACGTCTGGTACAA
CCTGGGGCACATTGCAGTGGGAATAGGAGACACAAACCTGGCCCACCAGTGCTTCAGGCTGGCC
CTGGTCCACAACAACCACCATGCTGAGGCCTACAACAACCTAGCCGTGCTGGAGATGCGGAAGG
GTCACATTGAACAGTTGTTAAACATTTTAATGAACCTCAATTTTTTTTTTATAAATGTGTATTT
TAAAAGTCTTTAATCCAAAAACAAAAGTTCTTAAGCATTAGCTATCGTTGAAAACTTAGGTCAG
AAATCTGCTTTAAAATTTTTTATGGCTCATAATGTGTGGTTTTATCATGAGTACTTTAATTAGA
ACGTTAAAATTTATATTTTAATAAACTTTTTATCAGAAACTTTGTATTGTATATTGCACTTTAA
AATAAATCAGTATGTAAA

hide sequence

RefSeq Acc Id:

NM_001399497 ⟹ NP_001386426

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,927,909 - 123,982,117 (+)	NCBI
mRatBN7.2	6	118,198,203 - 118,252,418 (+)	NCBI

RefSeq Acc Id:

NM_001399499 ⟹ NP_001386428

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,927,909 - 123,982,117 (+)	NCBI
mRatBN7.2	6	118,198,203 - 118,252,418 (+)	NCBI

RefSeq Acc Id:

XM_039112066 ⟹ XP_038967994

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,927,657 - 123,962,143 (+)	NCBI
mRatBN7.2	6	118,198,191 - 118,232,479 (+)	NCBI

RefSeq Acc Id:

XM_039112067 ⟹ XP_038967995

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,945,353 - 123,982,117 (+)	NCBI
mRatBN7.2	6	118,214,472 - 118,252,422 (+)	NCBI

RefSeq Acc Id:

XM_039112069 ⟹ XP_038967997

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,927,735 - 123,962,143 (+)	NCBI
mRatBN7.2	6	118,198,194 - 118,232,478 (+)	NCBI

RefSeq Acc Id:

XM_063261759 ⟹ XP_063117829

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,929,144 - 123,982,117 (+)	NCBI

RefSeq Acc Id:

XM_063261760 ⟹ XP_063117830

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,945,189 - 123,982,117 (+)	NCBI

RefSeq Acc Id:

XM_063261761 ⟹ XP_063117831

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,927,829 - 123,973,926 (+)	NCBI

RefSeq Acc Id:

XR_010052074

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,927,885 - 123,990,734 (+)	NCBI

RefSeq Acc Id:

XR_010052075

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,927,885 - 124,025,354 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100222	(Get FASTA)	NCBI Sequence Viewer
	NP_001386426	(Get FASTA)	NCBI Sequence Viewer
	NP_001386428	(Get FASTA)	NCBI Sequence Viewer
	XP_038967994	(Get FASTA)	NCBI Sequence Viewer
	XP_038967995	(Get FASTA)	NCBI Sequence Viewer
	XP_038967997	(Get FASTA)	NCBI Sequence Viewer
	XP_063117829	(Get FASTA)	NCBI Sequence Viewer
	XP_063117830	(Get FASTA)	NCBI Sequence Viewer
	XP_063117831	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI61880	(Get FASTA)	NCBI Sequence Viewer
	AQA28051	(Get FASTA)	NCBI Sequence Viewer
	AQA28052	(Get FASTA)	NCBI Sequence Viewer
	AQA28053	(Get FASTA)	NCBI Sequence Viewer
	AQA28054	(Get FASTA)	NCBI Sequence Viewer
	AQA28055	(Get FASTA)	NCBI Sequence Viewer
	AQA28056	(Get FASTA)	NCBI Sequence Viewer
	AQA28057	(Get FASTA)	NCBI Sequence Viewer
	AQA28058	(Get FASTA)	NCBI Sequence Viewer
	AQA28059	(Get FASTA)	NCBI Sequence Viewer
	AQA28060	(Get FASTA)	NCBI Sequence Viewer
	AQA28061	(Get FASTA)	NCBI Sequence Viewer
	AQA28062	(Get FASTA)	NCBI Sequence Viewer
	AQA28063	(Get FASTA)	NCBI Sequence Viewer
	AQA28064	(Get FASTA)	NCBI Sequence Viewer
	AQA28065	(Get FASTA)	NCBI Sequence Viewer
	AQA28066	(Get FASTA)	NCBI Sequence Viewer
	AQA28067	(Get FASTA)	NCBI Sequence Viewer
	AQA28068	(Get FASTA)	NCBI Sequence Viewer
	AQA28069	(Get FASTA)	NCBI Sequence Viewer
	AQA28070	(Get FASTA)	NCBI Sequence Viewer
	AQA28071	(Get FASTA)	NCBI Sequence Viewer
	AQA28072	(Get FASTA)	NCBI Sequence Viewer
	AQA28073	(Get FASTA)	NCBI Sequence Viewer
	AQA28074	(Get FASTA)	NCBI Sequence Viewer
	AQA28075	(Get FASTA)	NCBI Sequence Viewer
	AQA28076	(Get FASTA)	NCBI Sequence Viewer
	AQA28077	(Get FASTA)	NCBI Sequence Viewer
	AQA28078	(Get FASTA)	NCBI Sequence Viewer
	AQA28079	(Get FASTA)	NCBI Sequence Viewer
	AQA28080	(Get FASTA)	NCBI Sequence Viewer
	AQA28081	(Get FASTA)	NCBI Sequence Viewer
	AQA28082	(Get FASTA)	NCBI Sequence Viewer
	AQA28083	(Get FASTA)	NCBI Sequence Viewer
	AQA28084	(Get FASTA)	NCBI Sequence Viewer
	AQA28085	(Get FASTA)	NCBI Sequence Viewer
	AQA28086	(Get FASTA)	NCBI Sequence Viewer
	AQA28087	(Get FASTA)	NCBI Sequence Viewer
	AQA28088	(Get FASTA)	NCBI Sequence Viewer
	AQA28089	(Get FASTA)	NCBI Sequence Viewer
	AQA28090	(Get FASTA)	NCBI Sequence Viewer
	AQA28091	(Get FASTA)	NCBI Sequence Viewer
	AQA28092	(Get FASTA)	NCBI Sequence Viewer
	EDL81698	(Get FASTA)	NCBI Sequence Viewer
	EDL81699	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000060304
	ENSRNOP00000060304.1
	ENSRNOP00000068618
	ENSRNOP00000068618.1
	ENSRNOP00000077009.1
	ENSRNOP00000083411.1
	ENSRNOP00000085100
	ENSRNOP00000085100.1
	ENSRNOP00000085312
	ENSRNOP00000085312.1
	ENSRNOP00000088851.1
	ENSRNOP00000093561
	ENSRNOP00000093561.1
	ENSRNOP00000096518.1
	ENSRNOP00000097577.1

RefSeq Acc Id:	NP_001100222 ⟸ NM_001106752
- Peptide Label:	isoform 2
- UniProtKB:	D3ZND5 (UniProtKB/TrEMBL), A6JEF4 (UniProtKB/TrEMBL), A0A8I5ZJC8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGSEMEPLFRAWSYFRRRKFQLCADLCTQMLEKSPYDQAAWILKARALTEMVYVDEIDVDQEGI AEMTLDENAIAQVPRPGTSLKLPGTNQTGGPTQAVRPITQAGRPITGFLRPSTQSGRPGTMEQA IRTPRTAYTARPITSSSGRFVRLGTALFEYIFHHENDVKMKQIIIENELFSKALDLASLSTEYS QYKDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQEMVDTFLYLAKVYIILDQPVTALNLFKQG LDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRF YRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHIAVGIGD TNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQLLNILMNLNFFFINVYFKSL hide sequence

RefSeq Acc Id:

ENSRNOP00000068618 ⟸ ENSRNOT00000082856

RefSeq Acc Id:

ENSRNOP00000060304 ⟸ ENSRNOT00000068595

RefSeq Acc Id:	XP_038967994 ⟸ XM_039112066
- Peptide Label:	isoform X4
- UniProtKB:	A0A1P8YVD4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038967997 ⟸ XM_039112069
- Peptide Label:	isoform X6
- UniProtKB:	A0A1P8YVD8 (UniProtKB/TrEMBL), A0A1P8YVF9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038967995 ⟸ XM_039112067
- Peptide Label:	isoform X5
- UniProtKB:	A0A1P8YVE4 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000093561 ⟸ ENSRNOT00000097062

RefSeq Acc Id:

ENSRNOP00000083411 ⟸ ENSRNOT00000102593

RefSeq Acc Id:

ENSRNOP00000077009 ⟸ ENSRNOT00000118948

RefSeq Acc Id:

ENSRNOP00000096518 ⟸ ENSRNOT00000094918

RefSeq Acc Id:

ENSRNOP00000088851 ⟸ ENSRNOT00000114433

RefSeq Acc Id:

ENSRNOP00000085100 ⟸ ENSRNOT00000094428

RefSeq Acc Id:

ENSRNOP00000097577 ⟸ ENSRNOT00000114010

RefSeq Acc Id:

ENSRNOP00000085312 ⟸ ENSRNOT00000107635

RefSeq Acc Id:	NP_001386428 ⟸ NM_001399499
- Peptide Label:	isoform 3
- UniProtKB:	A0A1P8YVD0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386426 ⟸ NM_001399497
- Peptide Label:	isoform 1
- UniProtKB:	B1WBT5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063117831 ⟸ XM_063261761
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_063117829 ⟸ XM_063261759
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063117830 ⟸ XM_063261760
- Peptide Label:	isoform X2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B1WBT5-F1-model_v2	AlphaFold	B1WBT5	1-505	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694773

Promoter ID:

EPDNEW_R5296

Type:

initiation region

Name:

Ttc8_1

Description:

tetratricopeptide repeat domain 8

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	122,920,327 - 122,920,387	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307769	AgrOrtholog
BioCyc Gene	G2FUF-36532	BioCyc
Ensembl Genes	ENSRNOG00000004542	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000068595	ENTREZGENE
	ENSRNOT00000068595.3	UniProtKB/TrEMBL
	ENSRNOT00000082856	ENTREZGENE
	ENSRNOT00000082856.2	UniProtKB/TrEMBL
	ENSRNOT00000094428	ENTREZGENE
	ENSRNOT00000094428.1	UniProtKB/TrEMBL
	ENSRNOT00000094918.1	UniProtKB/TrEMBL
	ENSRNOT00000097062.1	UniProtKB/TrEMBL
	ENSRNOT00000102593.1	UniProtKB/TrEMBL
	ENSRNOT00000107635.1	UniProtKB/TrEMBL
	ENSRNOT00000114010.1	UniProtKB/TrEMBL
	ENSRNOT00000114433.1	UniProtKB/TrEMBL
	ENSRNOT00000118948.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7126409	IMAGE-MGC_LOAD
InterPro	BBS8	UniProtKB/TrEMBL
	TPR-like_helical	UniProtKB/TrEMBL
	TPR_repeat	UniProtKB/TrEMBL
KEGG Report	rno:299246	UniProtKB/TrEMBL
MGC_CLONE	MGC:187444	IMAGE-MGC_LOAD
NCBI Gene	299246	ENTREZGENE
PANTHER	PTHR44177	UniProtKB/TrEMBL
	TETRATRICOPEPTIDE REPEAT PROTEIN 8	UniProtKB/TrEMBL
Pfam	TPR_12	UniProtKB/TrEMBL
	TPR_16	UniProtKB/TrEMBL
	TPR_8	UniProtKB/TrEMBL
PhenoGen	Ttc8	PhenoGen
PROSITE	TPR	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000004542	RatGTEx
SMART	TPR	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48452	UniProtKB/TrEMBL
UniProt	A0A1P8YVD0	ENTREZGENE, UniProtKB/TrEMBL
	A0A1P8YVD2_RAT	UniProtKB/TrEMBL
	A0A1P8YVD4	ENTREZGENE, UniProtKB/TrEMBL
	A0A1P8YVD6_RAT	UniProtKB/TrEMBL
	A0A1P8YVD7_RAT	UniProtKB/TrEMBL
	A0A1P8YVD8	ENTREZGENE, UniProtKB/TrEMBL
	A0A1P8YVE2_RAT	UniProtKB/TrEMBL
	A0A1P8YVE4	ENTREZGENE, UniProtKB/TrEMBL
	A0A1P8YVE5_RAT	UniProtKB/TrEMBL
	A0A1P8YVF2_RAT	UniProtKB/TrEMBL
	A0A1P8YVF5_RAT	UniProtKB/TrEMBL
	A0A1P8YVF7_RAT	UniProtKB/TrEMBL
	A0A1P8YVF8_RAT	UniProtKB/TrEMBL
	A0A1P8YVF9	ENTREZGENE, UniProtKB/TrEMBL
	A0A1P8YVG2_RAT	UniProtKB/TrEMBL
	A0A1P8YVG3_RAT	UniProtKB/TrEMBL
	A0A1P8YVG4_RAT	UniProtKB/TrEMBL
	A0A1P8YVG5_RAT	UniProtKB/TrEMBL
	A0A1P8YVG6_RAT	UniProtKB/TrEMBL
	A0A1P8YVG7_RAT	UniProtKB/TrEMBL
	A0A1P8YVG8_RAT	UniProtKB/TrEMBL
	A0A1P8YVG9_RAT	UniProtKB/TrEMBL
	A0A1P8YVH6_RAT	UniProtKB/TrEMBL
	A0A1P8YVH7_RAT	UniProtKB/TrEMBL
	A0A8I5ZJC8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZVU2_RAT	UniProtKB/TrEMBL
	A0A8I6ASM6_RAT	UniProtKB/TrEMBL
	A0A8I6GM46_RAT	UniProtKB/TrEMBL
	A6JEF4	ENTREZGENE, UniProtKB/TrEMBL
	B1WBT5	ENTREZGENE, UniProtKB/TrEMBL
	D3ZND5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Ttc8	tetratricopeptide repeat domain 8	Ttc8_predicted	tetratricopeptide repeat domain 8 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Ttc8_predicted	tetratricopeptide repeat domain 8 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIA

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIA

Imported Disease Annotations - OMIM