Cyrib (CYFIP related Rac1 interactor B) - Rat Genome Database

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Pathways
Gene: Cyrib (CYFIP related Rac1 interactor B) Rattus norvegicus
Analyze
Symbol: Cyrib
Name: CYFIP related Rac1 interactor B
RGD ID: 1307697
Description: Predicted to enable MHC class Ib protein binding, via antigen binding activity groove and small GTPase binding activity. Predicted to be involved in several processes, including negative regulation of actin filament polymerization; positive regulation of memory T cell activation; and positive regulation of type II interferon production. Predicted to be located in cilium and mitochondrion. Orthologous to human CYRIB (CYFIP related Rac1 interactor B); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CYFIP-related Rac1 interactor B; Fam49b; family with sequence similarity 49, member B; hypothetical protein LOC299909; LOC299909; RGD1307697; similar to 0910001A06Rik protein; uncharacterized protein LOC299909
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8797,524,941 - 97,649,846 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl797,523,121 - 97,649,853 (-)EnsemblGRCr8
mRatBN7.2795,633,876 - 95,760,588 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl795,633,876 - 95,697,686 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx797,406,820 - 97,531,642 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0799,608,486 - 99,733,302 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0799,530,454 - 99,655,160 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07104,514,566 - 104,641,875 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7104,516,391 - 104,556,419 (-)Ensemblrn6Rnor6.0
Rnor_5.0791,517,911 - 91,644,771 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47101,150,480 - 101,275,452 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera792,233,570 - 92,357,399 (-)NCBICelera
RGSC_v3.17101,184,709 - 101,246,506 (-)NCBI
Cytogenetic Map7q33NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:19056867   PMID:20458337   PMID:22326026   PMID:22522492   PMID:22871113   PMID:23376485   PMID:29059164   PMID:30250061   PMID:31285585  


Genomics

Comparative Map Data
Cyrib
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8797,524,941 - 97,649,846 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl797,523,121 - 97,649,853 (-)EnsemblGRCr8
mRatBN7.2795,633,876 - 95,760,588 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl795,633,876 - 95,697,686 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx797,406,820 - 97,531,642 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0799,608,486 - 99,733,302 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0799,530,454 - 99,655,160 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07104,514,566 - 104,641,875 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7104,516,391 - 104,556,419 (-)Ensemblrn6Rnor6.0
Rnor_5.0791,517,911 - 91,644,771 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47101,150,480 - 101,275,452 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera792,233,570 - 92,357,399 (-)NCBICelera
RGSC_v3.17101,184,709 - 101,246,506 (-)NCBI
Cytogenetic Map7q33NCBI
CYRIB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388129,839,593 - 130,017,129 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8129,839,593 - 130,017,504 (-)Ensemblhg38GRCh38
GRCh378130,851,839 - 131,029,375 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368130,922,898 - 131,021,182 (-)NCBIBuild 36Build 36hg18NCBI36
Build 348130,922,899 - 131,021,182NCBI
Celera8127,031,822 - 127,130,443 (-)NCBICelera
Cytogenetic Map8q24.21NCBI
HuRef8126,170,455 - 126,302,342 (-)NCBIHuRef
CHM1_18130,892,084 - 131,069,252 (-)NCBICHM1_1
T2T-CHM13v2.08130,965,555 - 131,143,607 (-)NCBIT2T-CHM13v2.0
Cyrib
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391563,800,943 - 63,932,627 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1563,800,946 - 63,932,327 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381563,929,094 - 64,060,778 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1563,929,097 - 64,060,478 (-)Ensemblmm10GRCm38
MGSCv371563,760,649 - 63,892,010 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361563,758,763 - 63,890,121 (-)NCBIMGSCv36mm8
Celera1565,431,654 - 65,563,033 (-)NCBICelera
Cytogenetic Map15D1NCBI
cM Map1528.16NCBI
Cyrib
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554614,632,263 - 4,662,016 (-)Ensembl
ChiLan1.0NW_0049554614,634,324 - 4,786,723 (-)NCBIChiLan1.0ChiLan1.0
CYRIB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27147,210,064 - 147,386,043 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18122,726,860 - 122,902,812 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08126,478,020 - 126,653,936 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18129,209,655 - 129,341,048 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8129,209,655 - 129,272,844 (-)EnsemblpanPan2panpan1.1
CYRIB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11326,942,036 - 27,056,547 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1326,942,229 - 27,003,644 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1326,909,797 - 27,057,242 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01327,286,332 - 27,433,998 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1327,286,332 - 27,432,203 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11327,002,963 - 27,150,335 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01327,123,335 - 27,270,680 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01327,423,241 - 27,570,947 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cyrib
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530311,268,360 - 11,377,229 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647018,721,037 - 18,804,065 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647018,665,898 - 18,803,864 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYRIB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1410,476,137 - 10,643,395 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2410,736,165 - 10,859,545 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CYRIB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18124,308,911 - 124,406,261 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8124,307,049 - 124,345,548 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603915,634,158 - 15,808,284 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cyrib
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473525,820,175 - 25,894,193 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473525,752,675 - 25,894,193 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cyrib
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11238,158,043 - 238,284,855 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cyrib
425 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)792388565119280177Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)782111245123048330Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)771103011106126789Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)731770293110435881Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)773618702118618702Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)793302009131686183Rat
1298525Cm1Cardiac mass QTL 12.7heart mass (VT:0007028)heart wet weight (CMO:0000069)756625161101625161Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)771621154114982716Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)785043242130043242Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)785497398130497398Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
1331723Bw25Body weight QTL 253.348body mass (VT:0001259)body weight (CMO:0000012)796700404111672180Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)783626689128626689Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)782111382132099989Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)763889858108889858Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)755498584105834451Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
631201Panci1Pancreas inflammation QTL 100.001pancreas integrity trait (VT:0010560)percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)773557047118557047Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)782111245123048330Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)796700404118618702Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
10450862Kidm55Kidney mass QTL 554.9kidney mass (VT:0002707)kidney weight (CMO:0000081)772725037117725037Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)762963207107963207Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)763889858108889858Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
10450856Livw4Liver weight QTL 43.8liver mass (VT:0003402)liver weight (CMO:0000092)772725037117725037Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)778682549123682549Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)771621154119349044Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat

Markers in Region
RH12645  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2795,635,771 - 95,635,956 (+)MAPPERmRatBN7.2
Rnor_6.07104,516,462 - 104,516,646NCBIRnor6.0
Rnor_5.0791,519,807 - 91,519,991UniSTSRnor5.0
RGSC_v3.47101,150,553 - 101,150,737UniSTSRGSC3.4
Celera792,233,643 - 92,233,827UniSTS
Cytogenetic Map7q33UniSTS
RH141686  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2795,650,786 - 95,650,969 (+)MAPPERmRatBN7.2
Rnor_6.07104,531,927 - 104,532,109NCBIRnor6.0
Rnor_5.0791,535,064 - 91,535,246UniSTSRnor5.0
RGSC_v3.47101,165,579 - 101,165,761UniSTSRGSC3.4
Celera792,247,544 - 92,247,726UniSTS
RH 3.4 Map7661.8UniSTS
Cytogenetic Map7q33UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
28 14 94 250 91 90 59 208 59 6 575 346 24 236 134 145 31 51 51

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001126267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC166469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000078116   ⟹   ENSRNOP00000073189
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl797,523,121 - 97,649,853 (-)Ensembl
mRatBN7.2 Ensembl795,640,002 - 95,697,510 (-)Ensembl
Rnor_6.0 Ensembl7104,517,063 - 104,541,392 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000090784   ⟹   ENSRNOP00000070286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl797,523,121 - 97,586,753 (-)Ensembl
mRatBN7.2 Ensembl795,633,876 - 95,697,686 (-)Ensembl
Rnor_6.0 Ensembl7104,516,391 - 104,556,419 (-)Ensembl
RefSeq Acc Id: NM_001126267   ⟹   NP_001119739
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8797,524,941 - 97,649,812 (-)NCBI
mRatBN7.2795,635,699 - 95,760,588 (-)NCBI
Rnor_6.07104,516,389 - 104,641,795 (-)NCBI
Rnor_5.0791,517,911 - 91,644,771 (-)NCBI
RGSC_v3.47101,150,480 - 101,275,452 (-)RGD
Celera792,233,570 - 92,357,399 (-)RGD
Sequence:
RefSeq Acc Id: XM_006241633   ⟹   XP_006241695
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8797,524,941 - 97,586,673 (-)NCBI
mRatBN7.2795,633,876 - 95,697,522 (-)NCBI
Rnor_6.07104,514,566 - 104,578,771 (-)NCBI
Rnor_5.0791,517,911 - 91,644,771 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006241635   ⟹   XP_006241697
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8797,524,941 - 97,586,673 (-)NCBI
mRatBN7.2795,633,876 - 95,697,499 (-)NCBI
Rnor_6.07104,514,569 - 104,578,752 (-)NCBI
Rnor_5.0791,517,911 - 91,644,771 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765501   ⟹   XP_008763723
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8797,524,941 - 97,649,765 (-)NCBI
mRatBN7.2795,633,876 - 95,760,579 (-)NCBI
Rnor_6.07104,514,566 - 104,641,875 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594751   ⟹   XP_017450240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8797,524,941 - 97,649,765 (-)NCBI
mRatBN7.2795,633,876 - 95,760,579 (-)NCBI
Rnor_6.07104,514,566 - 104,641,874 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039078771   ⟹   XP_038934699
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8797,524,941 - 97,649,765 (-)NCBI
mRatBN7.2795,633,876 - 95,760,579 (-)NCBI
RefSeq Acc Id: XM_039078773   ⟹   XP_038934701
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8797,524,941 - 97,649,765 (-)NCBI
mRatBN7.2795,633,876 - 95,760,579 (-)NCBI
RefSeq Acc Id: XM_039078774   ⟹   XP_038934702
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8797,524,941 - 97,586,673 (-)NCBI
mRatBN7.2795,633,876 - 95,697,508 (-)NCBI
RefSeq Acc Id: XM_039078775   ⟹   XP_038934703
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8797,524,941 - 97,649,846 (-)NCBI
mRatBN7.2795,633,876 - 95,760,573 (-)NCBI
RefSeq Acc Id: XM_063263248   ⟹   XP_063119318
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8797,524,941 - 97,586,673 (-)NCBI
RefSeq Acc Id: NP_001119739   ⟸   NM_001126267
- UniProtKB: B2GUZ9 (UniProtKB/TrEMBL),   A0A0G2K4V6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241695   ⟸   XM_006241633
- Peptide Label: isoform X2
- UniProtKB: B2GUZ9 (UniProtKB/TrEMBL),   A0A0G2K4V6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241697   ⟸   XM_006241635
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JXI6 (UniProtKB/TrEMBL),   A6HRP7 (UniProtKB/TrEMBL),   A0A0G2K4V6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763723   ⟸   XM_008765501
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JXI6 (UniProtKB/TrEMBL),   A6HRP7 (UniProtKB/TrEMBL),   A0A0G2K4V6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450240   ⟸   XM_017594751
- Peptide Label: isoform X2
- UniProtKB: B2GUZ9 (UniProtKB/TrEMBL),   A0A0G2K4V6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070286   ⟸   ENSRNOT00000090784
Ensembl Acc Id: ENSRNOP00000073189   ⟸   ENSRNOT00000078116
RefSeq Acc Id: XP_038934701   ⟸   XM_039078773
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038934699   ⟸   XM_039078771
- Peptide Label: isoform X2
- UniProtKB: B2GUZ9 (UniProtKB/TrEMBL),   A0A0G2K4V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934703   ⟸   XM_039078775
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038934702   ⟸   XM_039078774
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063119318   ⟸   XM_063263248
- Peptide Label: isoform X2
- UniProtKB: B2GUZ9 (UniProtKB/TrEMBL),   A0A0G2K4V6 (UniProtKB/TrEMBL)
Protein Domains
CYRIA/CYRIB Rac1 binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2GUZ9-F1-model_v2 AlphaFold B2GUZ9 1-324 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307697 AgrOrtholog
BioCyc Gene G2FUF-33149 BioCyc
Ensembl Genes ENSRNOG00000061246 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000078116 ENTREZGENE
  ENSRNOT00000078116.3 UniProtKB/TrEMBL
  ENSRNOT00000090784 ENTREZGENE
  ENSRNOT00000090784.3 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9036548 IMAGE-MGC_LOAD
InterPro DUF1394 UniProtKB/TrEMBL
  FAM49 UniProtKB/TrEMBL
KEGG Report rno:299909 UniProtKB/TrEMBL
MGC_CLONE MGC:187849 IMAGE-MGC_LOAD
NCBI Gene 299909 ENTREZGENE
PANTHER PTHR12422 UniProtKB/TrEMBL
Pfam DUF1394 UniProtKB/TrEMBL
PhenoGen Cyrib PhenoGen
RatGTEx ENSRNOG00000061246 RatGTEx
UniProt A0A0G2JXI6 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K4V6 ENTREZGENE, UniProtKB/TrEMBL
  A6HRP7 ENTREZGENE, UniProtKB/TrEMBL
  B2GUZ9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-12-06 Cyrib  CYFIP related Rac1 interactor B  Fam49b  family with sequence similarity 49, member B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Fam49b  family with sequence similarity 49, member B  RGD1307697_predicted  similar to 0910001A06Rik protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1307697_predicted  similar to 0910001A06Rik protein (predicted)  LOC299909_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC299909_predicted  similar to 0910001A06Rik protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL