Tbc1d7 (TBC1 domain family, member 7) - Rat Genome Database

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Gene: Tbc1d7 (TBC1 domain family, member 7) Rattus norvegicus
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Symbol: Tbc1d7
Name: TBC1 domain family, member 7
RGD ID: 1307661
Description: Predicted to enable GTPase activator activity; TSC1-TSC2 complex binding activity; and small GTPase binding activity. Predicted to be involved in several processes, including negative regulation of TORC1 signaling; negative regulation of cilium assembly; and positive regulation of protein ubiquitination. Predicted to be located in ciliary basal body; cytoplasmic vesicle; and cytosol. Predicted to be part of TSC1-TSC2 complex. Predicted to be active in lysosomal membrane. Orthologous to human TBC1D7 (TBC1 domain family member 7); PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC361227; TBC1 domain family member 7
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81721,736,898 - 21,754,499 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1721,736,913 - 21,755,108 (+)EnsemblGRCr8
mRatBN7.21721,530,709 - 21,548,556 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1721,531,016 - 21,548,553 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1721,419,590 - 21,436,641 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01723,023,254 - 23,040,309 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01721,346,690 - 21,363,740 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01723,774,793 - 23,792,389 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1723,775,220 - 23,792,353 (-)Ensemblrn6Rnor6.0
Rnor_5.01725,726,868 - 25,744,430 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41727,360,670 - 27,377,803 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1721,227,501 - 21,244,566 (+)NCBICelera
RGSC_v3.11727,364,984 - 27,380,364 (+)NCBI
Cytogenetic Map17p14NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Regulation of mTORC1 by PI3K signaling. Dibble CC and Cantley LC, Trends Cell Biol. 2015 Sep;25(9):545-55. doi: 10.1016/j.tcb.2015.06.002. Epub 2015 Jul 6.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17646400   PMID:17658474   PMID:22795129  


Genomics

Comparative Map Data
Tbc1d7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81721,736,898 - 21,754,499 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1721,736,913 - 21,755,108 (+)EnsemblGRCr8
mRatBN7.21721,530,709 - 21,548,556 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1721,531,016 - 21,548,553 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1721,419,590 - 21,436,641 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01723,023,254 - 23,040,309 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01721,346,690 - 21,363,740 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01723,774,793 - 23,792,389 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1723,775,220 - 23,792,353 (-)Ensemblrn6Rnor6.0
Rnor_5.01725,726,868 - 25,744,430 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41727,360,670 - 27,377,803 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1721,227,501 - 21,244,566 (+)NCBICelera
RGSC_v3.11727,364,984 - 27,380,364 (+)NCBI
Cytogenetic Map17p14NCBI
TBC1D7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38613,266,536 - 13,328,537 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl613,266,542 - 13,328,583 (-)Ensemblhg38GRCh38
GRCh37613,266,768 - 13,328,769 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36613,413,162 - 13,436,593 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34613,413,162 - 13,436,593NCBI
Celera614,538,134 - 14,561,738 (-)NCBICelera
Cytogenetic Map6p24.1NCBI
HuRef613,242,164 - 13,265,772 (-)NCBIHuRef
CHM1_1613,269,098 - 13,331,159 (-)NCBICHM1_1
T2T-CHM13v2.0613,139,813 - 13,201,777 (-)NCBIT2T-CHM13v2.0
Tbc1d7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391343,305,214 - 43,324,977 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1343,305,216 - 43,324,977 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381343,151,740 - 43,171,501 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1343,151,740 - 43,171,501 (-)Ensemblmm10GRCm38
MGSCv371343,247,113 - 43,266,728 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361343,162,716 - 43,182,331 (-)NCBIMGSCv36mm8
Celera1344,236,751 - 44,256,441 (-)NCBICelera
Cytogenetic Map13A4NCBI
cM Map1321.31NCBI
Tbc1d7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554651,362,759 - 1,382,190 (+)Ensembl
ChiLan1.0NW_0049554651,362,453 - 1,380,814 (+)NCBIChiLan1.0ChiLan1.0
TBC1D7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2527,959,687 - 27,983,685 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1623,917,815 - 23,973,698 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0613,150,677 - 13,174,661 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1613,491,734 - 13,546,859 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl613,491,734 - 13,546,853 (-)EnsemblpanPan2panpan1.1
Tbc1d7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494611,739,260 - 11,753,493 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365348,281 - 27,544 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365348,104 - 17,056 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBC1D7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl79,685,266 - 9,708,781 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.179,685,273 - 9,708,781 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2710,026,850 - 10,049,820 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TBC1D7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11758,822,288 - 58,844,659 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1758,822,415 - 58,846,047 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604413,347,730 - 13,370,863 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbc1d7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475612,903,359 - 12,921,805 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475612,902,917 - 12,921,805 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Tbc1d7
351 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:50
Count of miRNA genes:46
Interacting mature miRNAs:50
Transcripts:ENSRNOT00000019089
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17143999106Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17926675540968173Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17436005727233623Rat
8552966Pigfal18Plasma insulin-like growth factor 1 level QTL 188.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)171286094257860942Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17212084342054133Rat
1582224Epfw4Epididymal fat weight QTL 43.50.0058epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)17920650523859062Rat
1582225Bw67Body weight QTL 676.20.0001body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)17622199858177198Rat
1582226Bw64Body weight QTL 644.20.0017body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
9589151Insul30Insulin level QTL 308.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)171286094257860942Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172149899450592236Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131706603Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17473353449733534Rat
9589057Scfw6Subcutaneous fat weight QTL 68.620.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)171286094257860942Rat
1582208Kidm32Kidney mass QTL 323.90.0018kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17920650523859062Rat
9590154Scort9Serum corticosterone level QTL 923.570.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)171286094257860942Rat
9590088Insglur7Insulin/glucose ratio QTL 720.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)171286094257860942Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)17122181410Rat
1331720Rf43Renal function QTL 432.881kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)171553702528637951Rat
2317053Aia25Adjuvant induced arthritis QTL 252.69joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)171060469455604694Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17136045694Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171553702560531414Rat
7411666Foco31Food consumption QTL 3111.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)171286094257860942Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17473353449733534Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17857434232199534Rat
1582258Bw76Body weight QTL 764.60.0005body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17138037084Rat
1582199Insul5Insulin level QTL 53.40.0119blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)17920650523859062Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17143999106Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17436005727233623Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17143999106Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17212084322087569Rat
1582241Bw70Body weight QTL 704.60.0003body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
1582245Bw73Body weight QTL 734.60.0004body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122877318Rat

Markers in Region
AI230799  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21721,532,879 - 21,533,080 (-)MAPPERmRatBN7.2
Rnor_6.01723,790,267 - 23,790,467NCBIRnor6.0
Rnor_5.01725,742,342 - 25,742,542UniSTSRnor5.0
RGSC_v3.41727,362,556 - 27,362,756UniSTSRGSC3.4
Celera1721,229,395 - 21,229,595UniSTS
RH 3.4 Map17267.3UniSTS
Cytogenetic Map17p12UniSTS
AI171242  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21721,548,163 - 21,548,274 (-)MAPPERmRatBN7.2
Rnor_6.01723,775,075 - 23,775,185NCBIRnor6.0
Rnor_6.01723,713,164 - 23,713,274NCBIRnor6.0
Rnor_5.01725,727,150 - 25,727,260UniSTSRnor5.0
Rnor_5.01725,667,333 - 25,667,443UniSTSRnor5.0
RGSC_v3.41727,377,838 - 27,377,948UniSTSRGSC3.4
Celera1721,244,601 - 21,244,711UniSTS
RH 3.4 Map17267.9UniSTS
Cytogenetic Map17p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000019089   ⟹   ENSRNOP00000019089
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1721,736,931 - 21,754,498 (+)Ensembl
mRatBN7.2 Ensembl1721,531,016 - 21,548,553 (+)Ensembl
Rnor_6.0 Ensembl1723,775,220 - 23,792,353 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105011   ⟹   ENSRNOP00000083656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1721,736,930 - 21,755,108 (+)Ensembl
mRatBN7.2 Ensembl1721,531,016 - 21,548,553 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000141058   ⟹   ENSRNOP00000106262
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1721,736,913 - 21,755,108 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000143207   ⟹   ENSRNOP00000108977
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1721,736,964 - 21,755,096 (+)Ensembl
RefSeq Acc Id: NM_001108411   ⟹   NP_001101881
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81721,736,939 - 21,754,072 (+)NCBI
mRatBN7.21721,530,994 - 21,548,129 (+)NCBI
Rnor_6.01723,775,220 - 23,792,353 (-)NCBI
Rnor_5.01725,726,868 - 25,744,430 (-)NCBI
RGSC_v3.41727,360,670 - 27,377,803 (+)RGD
Celera1721,227,501 - 21,244,566 (+)RGD
Sequence:
RefSeq Acc Id: XM_006253830   ⟹   XP_006253892
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81721,736,905 - 21,754,499 (+)NCBI
mRatBN7.21721,530,979 - 21,548,556 (+)NCBI
Rnor_6.01723,774,793 - 23,792,389 (-)NCBI
Rnor_5.01725,726,868 - 25,744,430 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006253831   ⟹   XP_006253893
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81721,736,900 - 21,754,499 (+)NCBI
mRatBN7.21721,530,979 - 21,548,556 (+)NCBI
Rnor_6.01723,774,793 - 23,792,389 (-)NCBI
Rnor_5.01725,726,868 - 25,744,430 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039095869   ⟹   XP_038951797
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81721,736,900 - 21,754,499 (+)NCBI
mRatBN7.21721,530,979 - 21,548,556 (+)NCBI
RefSeq Acc Id: XM_063276570   ⟹   XP_063132640
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81721,736,909 - 21,754,499 (+)NCBI
RefSeq Acc Id: XM_063276571   ⟹   XP_063132641
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81721,736,909 - 21,754,499 (+)NCBI
RefSeq Acc Id: XM_063276572   ⟹   XP_063132642
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81721,736,900 - 21,754,499 (+)NCBI
RefSeq Acc Id: XM_063276573   ⟹   XP_063132643
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81721,736,900 - 21,754,499 (+)NCBI
RefSeq Acc Id: XM_063276575   ⟹   XP_063132645
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81721,736,900 - 21,750,938 (+)NCBI
RefSeq Acc Id: XM_063276576   ⟹   XP_063132646
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81721,736,900 - 21,754,499 (+)NCBI
RefSeq Acc Id: XM_063276577   ⟹   XP_063132647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81721,736,898 - 21,746,246 (+)NCBI
RefSeq Acc Id: XM_063276578   ⟹   XP_063132648
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81721,736,903 - 21,745,931 (+)NCBI
RefSeq Acc Id: NP_001101881   ⟸   NM_001108411
- UniProtKB: A6J751 (UniProtKB/TrEMBL),   A0A8I5ZX17 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253893   ⟸   XM_006253831
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZX17 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253892   ⟸   XM_006253830
- Peptide Label: isoform X2
- UniProtKB: D4AAY4 (UniProtKB/TrEMBL),   A0A8I5ZX17 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000019089   ⟸   ENSRNOT00000019089
RefSeq Acc Id: XP_038951797   ⟸   XM_039095869
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZX17 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000083656   ⟸   ENSRNOT00000105011
RefSeq Acc Id: XP_063132647   ⟸   XM_063276577
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063132642   ⟸   XM_063276572
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063132643   ⟸   XM_063276573
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063132646   ⟸   XM_063276576
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063132645   ⟸   XM_063276575
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063132648   ⟸   XM_063276578
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063132640   ⟸   XM_063276570
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZX17 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132641   ⟸   XM_063276571
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZX17 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000106262   ⟸   ENSRNOT00000141058
Ensembl Acc Id: ENSRNOP00000108977   ⟸   ENSRNOT00000143207
Protein Domains
Rab-GAP TBC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AAY4-F1-model_v2 AlphaFold D4AAY4 1-293 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700384
Promoter ID:EPDNEW_R10908
Type:initiation region
Name:Tbc1d7_1
Description:TBC1 domain family, member 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01723,792,331 - 23,792,391EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307661 AgrOrtholog
BioCyc Gene G2FUF-9792 BioCyc
Ensembl Genes ENSRNOG00000014019 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019089 ENTREZGENE
  ENSRNOT00000019089.8 UniProtKB/TrEMBL
  ENSRNOT00000105011.2 UniProtKB/TrEMBL
  ENSRNOT00000141058 ENTREZGENE
  ENSRNOT00000141058.1 UniProtKB/TrEMBL
  ENSRNOT00000143207 ENTREZGENE
  ENSRNOT00000143207.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.680 UniProtKB/TrEMBL
  Ypt/Rab-GAP domain of gyp1p, domain 1 UniProtKB/TrEMBL
  Ypt/Rab-GAP domain of gyp1p, domain 3 UniProtKB/TrEMBL
InterPro Rab-GTPase_TBC_sf UniProtKB/TrEMBL
  RabGAP_TBC UniProtKB/TrEMBL
  TBC1D7 UniProtKB/TrEMBL
  TBC1D7_dom2 UniProtKB/TrEMBL
KEGG Report rno:361227 UniProtKB/TrEMBL
NCBI Gene 361227 ENTREZGENE
PANTHER PTHR13530 UniProtKB/TrEMBL
  TBC1 DOMAIN FAMILY MEMBER 7 UniProtKB/TrEMBL
Pfam TBC UniProtKB/TrEMBL
PhenoGen Tbc1d7 PhenoGen
PROSITE TBC_RABGAP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014019 RatGTEx
Superfamily-SCOP RabGAP_TBC UniProtKB/TrEMBL
UniProt A0A8I5ZX17 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LQU0_RAT UniProtKB/TrEMBL
  A0ABK0M1L8_RAT UniProtKB/TrEMBL
  A6J751 ENTREZGENE, UniProtKB/TrEMBL
  D4AAY4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Tbc1d7  TBC1 domain family, member 7   Tbc1d7_predicted  TBC1 domain family, member 7 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Tbc1d7_predicted  TBC1 domain family, member 7 (predicted)      Symbol and Name status set to approved 70820 APPROVED