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Gene: Rhoh (ras homolog family member H) Rattus norvegicus

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Symbol:

Rhoh

Name:

ras homolog family member H

RGD ID:

1307623

Description:

Predicted to enable several functions, including GTP binding activity; GTPase activity; and kinase inhibitor activity. Predicted to be involved in several processes, including mast cell activation; negative regulation of canonical NF-kappaB signal transduction; and positive regulation of T cell differentiation. Predicted to be located in cytoplasm and immunological synapse. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in immunodeficiency 129. Orthologous to human RHOH (ras homolog family member H); INTERACTS WITH 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil; acetamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC305341; MGC109123; ras homolog gene family, member H; rho-related GTP-binding protein RhoH

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RHOH (ras homolog family member H)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Rhoh (ras homolog family member H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rhoh (ras homolog family member H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RHOH (ras homolog family member H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RHOH (ras homolog family member H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rhoh (ras homolog family member H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RHOH (ras homolog family member H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RHOH (ras homolog family member H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rhoh (ras homolog family member H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Rhoh (ras homolog family member H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PDC (phosducin)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	RHOH (ras homolog family member H)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rhoh (ras homolog family member H)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rhoh (ras homolog family member H)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	RhoL	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	rhoh	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	42,694,860 - 42,725,690 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	42,693,413 - 42,749,967 (-)	Ensembl				GRCr8
mRatBN7.2	14	42,341,135 - 42,371,971 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	42,337,751 - 42,386,369 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	42,695,015 - 42,725,936 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	43,995,052 - 44,025,974 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	42,475,045 - 42,505,966 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	43,961,756 - 43,992,587 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	43,961,756 - 43,992,587 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	43,781,206 - 43,812,028 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	45,024,482 - 45,055,940 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	41,494,501 - 41,525,255 (-)	NCBI		Celera
RGSC_v3.1	14	45,026,872 - 45,058,331 (-)	NCBI
Cytogenetic Map	14	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

coronin-1A deficiency (ISO)

immunodeficiency 129 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-anisomycin (ISO)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

15-acetyldeoxynivalenol (ISO)

2-palmitoylglycerol (ISO)

3-methylcholanthrene (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

amitrole (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzoates (ISO)

bisphenol A (EXP,ISO)

buta-1,3-diene (ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

CGP 52608 (ISO)

chloroprene (ISO)

choline (ISO)

cisplatin (ISO)

Cuprizon (EXP)

deoxynivalenol (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

dimethylarsinic acid (ISO)

disodium selenite (ISO)

dorsomorphin (ISO)

entinostat (ISO)

folic acid (ISO)

gentamycin (EXP)

L-methionine (ISO)

methimazole (EXP)

methyl methanesulfonate (ISO)

methylarsonic acid (ISO)

methylmercury chloride (ISO)

N-nitrosodiethylamine (ISO)

nickel atom (ISO)

nitrates (ISO)

ouabain (ISO)

panobinostat (ISO)

paracetamol (ISO)

phenylmercury acetate (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

T-2 toxin (EXP)

Tetrachlorobisphenol A (ISO)

thapsigargin (ISO)

Theaflavin 3,3'-digallate (ISO)

thioacetamide (EXP)

toluene (ISO)

Tributyltin oxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin filament organization (IBA)

mast cell activation (IEA,ISO)

negative regulation of canonical NF-kappaB signal transduction (IEA,ISO)

positive regulation of T cell differentiation (IEA,ISO)

signal transduction (IBA)

small GTPase-mediated signal transduction (IEA)

T cell differentiation (IEA,ISO)

Cellular Component

cytoplasm (IEA,ISO)

immunological synapse (IEA,ISO)

plasma membrane (IBA,IEA,ISO)

Molecular Function

GTP binding (IBA,IEA,ISO)

GTPase activity (IBA,IEA)

kinase inhibitor activity (IEA,ISO)

nucleotide binding (IEA)

protein binding (ISO)

protein kinase binding (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:11809807	PMID:17028588	PMID:17119112	PMID:19124738	PMID:22850876

Genomics

Comparative Map Data

Rhoh
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	42,694,860 - 42,725,690 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	42,693,413 - 42,749,967 (-)	Ensembl				GRCr8
mRatBN7.2	14	42,341,135 - 42,371,971 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	42,337,751 - 42,386,369 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	42,695,015 - 42,725,936 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	43,995,052 - 44,025,974 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	42,475,045 - 42,505,966 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	43,961,756 - 43,992,587 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	43,961,756 - 43,992,587 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	43,781,206 - 43,812,028 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	45,024,482 - 45,055,940 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	41,494,501 - 41,525,255 (-)	NCBI		Celera
RGSC_v3.1	14	45,026,872 - 45,058,331 (-)	NCBI
Cytogenetic Map	14	p11	NCBI

RHOH
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	40,191,080 - 40,246,967 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	40,191,011 - 40,246,967 (+)	Ensembl			hg38	GRCh38
GRCh37	4	40,192,700 - 40,248,587 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	39,874,922 - 39,922,676 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	4	40,021,167 - 40,068,419	NCBI
Celera	4	40,637,435 - 40,685,176 (+)	NCBI		Celera
Cytogenetic Map	4	p14	NCBI
HuRef	4	39,515,874 - 39,569,650 (+)	NCBI		HuRef
CHM1_1	4	40,191,833 - 40,245,593 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	40,161,181 - 40,217,041 (+)	NCBI		T2T-CHM13v2.0

Rhoh
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	66,018,092 - 66,054,043 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	66,018,556 - 66,054,043 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	65,860,742 - 65,896,700 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	65,861,213 - 65,896,700 (+)	Ensembl			mm10	GRCm38
MGSCv37	5	66,254,808 - 66,287,939 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	66,140,350 - 66,175,835 (+)	NCBI		MGSCv36	mm8
Celera	5	63,159,997 - 63,193,217 (+)	NCBI		Celera
Cytogenetic Map	5	C3.1	NCBI
cM Map	5	33.8	NCBI

Rhoh
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955443	7,227,751 - 7,264,821 (-)	Ensembl
ChiLan1.0	NW_004955443	7,227,751 - 7,269,984 (-)	NCBI	ChiLan1.0	ChiLan1.0

RHOH
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	40,381,386 - 40,430,592 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	40,573,329 - 40,622,540 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	34,517,487 - 34,569,934 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	40,374,816 - 40,420,753 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	40,419,549 - 40,420,124 (+)	Ensembl			panPan2	panpan1.1

RHOH
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	72,272,446 - 72,277,015 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	72,276,418 - 72,276,993 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	74,822,104 - 74,825,439 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	73,040,298 - 73,043,633 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	73,039,977 - 73,089,743 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	72,309,276 - 72,312,610 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	72,459,426 - 72,462,761 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	72,843,539 - 72,846,874 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rhoh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	38,574,902 - 38,615,064 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936482	7,689,371 - 7,723,321 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936482	7,721,815 - 7,723,395 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RHOH
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	31,321,059 - 31,372,364 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	8	31,321,005 - 31,372,366 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	32,988,403 - 33,036,670 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RHOH
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	27	10,061,316 - 10,109,124 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	27	10,062,014 - 10,062,589 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666047	56,429,868 - 56,477,900 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rhoh
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624761	26,720,478 - 26,721,053 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624761	26,717,857 - 26,721,628 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rhoh
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	11	22,960,673 - 22,961,918 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rhoh
84 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	206
Count of miRNA genes:	139
Interacting mature miRNAs:	156
Transcripts:	ENSRNOT00000003425
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313089	Bss81	Bone structure and strength QTL 81	3.4	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	14	38023710	83023710	Rat
70214	Niddm28	Non-insulin dependent diabetes mellitus QTL 28	4.06		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	39009444	84009444	Rat
1300154	Bp189	Blood pressure QTL 189	3.04		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	14	31238080	72970315	Rat
70187	Pancm5	Pancreatic morphology QTL 5	16.7		pancreas mass (VT:0010144)	pancreas weight to body weight ratio (CMO:0000630)	14	30674469	85041098	Rat
631523	Pia13	Pristane induced arthritis QTL 13	3.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	33424686	102238540	Rat
1358296	Ael3	Aortic elastin QTL 3	3.7	0.00051	aorta elastin amount (VT:0003905)	aortic elastin	14	8621398	53621398	Rat
2313100	Bss82	Bone structure and strength QTL 82	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	14	38023710	83023710	Rat
7387267	Uae42	Urinary albumin excretion QTL 42		0.61	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	14	22521517	67521517	Rat
631839	Niddm37	Non-insulin dependent diabetes mellitus QTL 37	3.37		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11334716	100078267	Rat
2313397	Coatc1	Coat color QTL1			coat/hair pigmentation trait (VT:0010463)	coat/hair color measurement (CMO:0001808)	14	18895192	63895192	Rat
631262	Tcas4	Tongue tumor susceptibility QTL 4	7.29		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	14	17906726	54251504	Rat
1300136	Rf22	Renal function QTL 22	3.9		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	14	42616258	99224555	Rat
2313048	Bss84	Bone structure and strength QTL 84	3.1	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	14	38023710	83023710	Rat
2302045	Pia39	Pristane induced arthritis QTL 39	4.9	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G2a level (CMO:0002116)	14	8621398	53621398	Rat
738037	Hcas6	Hepatocarcinoma susceptibility QTL 6	2.93		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	14	39411170	87582095	Rat
2313084	Bss83	Bone structure and strength QTL 83	2.9	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	14	38023710	83023710	Rat

Markers in Region

RH141876

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	42,341,178 - 42,341,358 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	43,961,800 - 43,961,979	NCBI	Rnor6.0
Rnor_5.0	14	43,781,250 - 43,781,429	UniSTS	Rnor5.0
RGSC_v3.4	14	45,024,526 - 45,024,705	UniSTS	RGSC3.4
Celera	14	41,494,545 - 41,494,724	UniSTS
Cytogenetic Map	14	p11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	162	91	90	59	92	59	6	356	192	11	138	81	92	31	14	14

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013430	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC091449	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC091269	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ225032	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ225173	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228192	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232983	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000003425 ⟹ ENSRNOP00000003425

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	42,694,875 - 42,696,536 (-)	Ensembl
mRatBN7.2 Ensembl	14	42,341,135 - 42,386,369 (-)	Ensembl
Rnor_6.0 Ensembl	14	43,961,756 - 43,992,587 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000110238 ⟹ ENSRNOP00000094121

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	42,693,413 - 42,726,052 (-)	Ensembl
mRatBN7.2 Ensembl	14	42,337,751 - 42,372,160 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115442 ⟹ ENSRNOP00000078680

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	42,694,769 - 42,740,516 (-)	Ensembl
mRatBN7.2 Ensembl	14	42,340,344 - 42,346,884 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000136710 ⟹ ENSRNOP00000100850

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	42,694,864 - 42,696,414 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000143827 ⟹ ENSRNOP00000101404

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	42,694,905 - 42,725,757 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000149467 ⟹ ENSRNOP00000100460

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	42,694,862 - 42,749,967 (-)	Ensembl

RefSeq Acc Id:

NM_001013430 ⟹ NP_001013448

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	42,694,860 - 42,725,690 (-)	NCBI
mRatBN7.2	14	42,341,135 - 42,371,971 (-)	NCBI
Rnor_6.0	14	43,961,756 - 43,992,587 (-)	NCBI
Rnor_5.0	14	43,781,206 - 43,812,028 (-)	NCBI
RGSC_v3.4	14	45,024,482 - 45,055,940 (-)	RGD
Celera	14	41,494,501 - 41,525,255 (-)	RGD

Sequence:

show sequence

GTTCCTGCTGTCGGTCACCTCGGACACCAAGAGCCACCACCTCTGGTGGACTCTGCCAGTCCAG
TGTTACAAATTTTCCGACAGTGATTCACTGGGAGCCTTGAGAGGTAGCTTAGCTCCCAGGAGGA
ACTCTCAGCAGTGATAGGTTTTAGCTACCCTAGATTTTACATGGCGTCGAGAGCTACTTAGACT
TCCGGAGTCAGTGGTTTTGGTGTTGAGACCTTCATTTGGCATTCTACAACAGTTCCCAAAGTGA
CTGAGATCTACTAGAACCCTGAGGCCACAAACACGCAGCTGCCTTTGCCTGGGTTCTTTTCTGC
TTCTTGGCCAGTCAACAGCTGTTCACGAGTGTCATTCACACATCAGTTGGCAGCCACGCGTCAG
AGGTTTCCCACTGCTTCTCACCTGGCCAGACTGGAGACGCAACATCTGTAACCGATGTCTGAGA
TTCTACGAACATAAGCCCCAGTTGTTGTCTCCTCACTCTATGGAACCTGTTATAGAAACCCATT
GAGGGTTCTTCCCCTTGAGATCCTAGACTCTTAGATACAACTTCAGACGAGGAAGATGCTGAGC
TCTATCAAGTGTGTGCTGGTCGGCGACAGTGCTGTGGGAAAAACCTCACTGTTGGTGCGCTTCA
CCTCTGAGACCTTCCCCGAGGCCTACAAACCCACTGTGTATGAGAATACAGGTGTAGACGTCTT
CATGGATGGCATCCAGATCAGCCTGGGTCTCTGGGACACTGCAGGCAATGATGCCTTCAGAAGC
ATCCGCCCCCTGTCCTACCAGCAGGCAGATGTGGTACTAATGTGTTACTCGGTGGCCAACCATA
GCTCGTTCCTGAACTTGAAGAACAAATGGATTAGTGAGGTCAGGAGCAACCTACCCTGTACCCC
GGTGCTGGTGGTGGCCACTCAGACTGACCAGAGAGAGATGGGACCTCACAGGGCTTCCTGCATC
AATGCCATAGAAGGGAAGAGACTTGCCCAGGATGTGCGAGCCAAGGGCTACCTGGAGTGCTCAG
CCCTTAGCAACCGGGGAGTCCAGCAGGTATTTGAATGTGCTGTCCGAACAGCTGTCAACCAGGC
CAGGAGACGAAATAGAAGGAAGCTGTTTTCCATCAACGAATGCAAGATCTTCTAACCCCGAGGT
CCTGTACCCAACATTCATGAACATACCTCAAAGACTCATGGGAGAGGGGAAGGGGGCAAGCCAC
GAGGACCGATCTTGACCGATCTTGGCACATCTGAACAATCTTTCAGTTATGGGGAAGTCTGCCA
CTGATGCTTTCACAAACTGTACTCTGCAGATGAACTCTGTGCCAACACAACCTGAGAGATTCCT
TGGGGAGCCATGTGAGAAGTCCGTCTTCAATGAGAGATTAAAACGACCATCCTAATTTAGACAA
TGAAGTGCATTTCCCAAGTATGCTGTATTTAAACCCACATCTTATTTAAATAATGACCAAATAT
AGAGCTCTTGTTTTCCTGTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001013448	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH91269	(Get FASTA)	NCBI Sequence Viewer
	EDL90051	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000003425.4
	ENSRNOP00000078680.1
	ENSRNOP00000094121
	ENSRNOP00000094121.1
	ENSRNOP00000100460.1
	ENSRNOP00000100850.1
	ENSRNOP00000101404.1

RefSeq Acc Id:	NP_001013448 ⟸ NM_001013430
- UniProtKB:	Q5BJZ5 (UniProtKB/TrEMBL), A0A8I5ZLD5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTAGNDA FRSIRPLSYQQADVVLMCYSVANHSSFLNLKNKWISEVRSNLPCTPVLVVATQTDQREMGPHRA SCINAIEGKRLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRRKLFSINECKIF hide sequence

Ensembl Acc Id:

ENSRNOP00000003425 ⟸ ENSRNOT00000003425

Ensembl Acc Id:

ENSRNOP00000094121 ⟸ ENSRNOT00000110238

Ensembl Acc Id:

ENSRNOP00000078680 ⟸ ENSRNOT00000115442

Ensembl Acc Id:

ENSRNOP00000100460 ⟸ ENSRNOT00000149467

Ensembl Acc Id:

ENSRNOP00000100850 ⟸ ENSRNOT00000136710

Ensembl Acc Id:

ENSRNOP00000101404 ⟸ ENSRNOT00000143827

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5BJZ5-F1-model_v2	AlphaFold	Q5BJZ5	1-191	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699309

Promoter ID:

EPDNEW_R9834

Type:

initiation region

Name:

Rhoh_1

Description:

ras homolog family member H

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	43,992,647 - 43,992,707	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307623	AgrOrtholog
BioCyc Gene	G2FUF-15755	BioCyc
Ensembl Genes	ENSRNOG00000002540	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000003425.6	UniProtKB/TrEMBL
	ENSRNOT00000110238	ENTREZGENE
	ENSRNOT00000110238.2	UniProtKB/TrEMBL
	ENSRNOT00000115442.2	UniProtKB/TrEMBL
	ENSRNOT00000136710.1	UniProtKB/TrEMBL
	ENSRNOT00000143827.1	UniProtKB/TrEMBL
	ENSRNOT00000149467.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7381512	IMAGE-MGC_LOAD
InterPro	P-loop_NTPase	UniProtKB/TrEMBL
	Ras_GTPase	UniProtKB/TrEMBL
	Small_GTP_bd	UniProtKB/TrEMBL
	Small_GTPase_Rho	UniProtKB/TrEMBL
KEGG Report	rno:305341	UniProtKB/TrEMBL
MGC_CLONE	MGC:109123	IMAGE-MGC_LOAD
NCBI Gene	305341	ENTREZGENE
PANTHER	PTHR24072	UniProtKB/TrEMBL
Pfam	Ras	UniProtKB/TrEMBL
PhenoGen	Rhoh	PhenoGen
PRINTS	RASTRNSFRMNG	UniProtKB/TrEMBL
PROSITE	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000002540	RatGTEx
SMART	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A8I5ZLD5	ENTREZGENE, UniProtKB/TrEMBL
	Q5BJZ5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-10-15	Rhoh	ras homolog family member H	Rhoh	ras homolog gene family, member H	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Rhoh	ras homolog gene family, member H	Rhoh_predicted	ras homolog gene family, member H (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Rhoh_predicted	ras homolog gene family, member H (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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