Rhoh (ras homolog family member H) - Rat Genome Database

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Gene: Rhoh (ras homolog family member H) Chinchilla lanigera
Analyze
Symbol: Rhoh
Name: ras homolog family member H
RGD ID: 8821472
Description: ENCODES a protein that exhibits GTP binding (ortholog); kinase inhibitor activity (ortholog); INVOLVED IN mast cell activation (ortholog); negative regulation of canonical NF-kappaB signal transduction (ortholog); positive regulation of T cell differentiation (ortholog); ASSOCIATED WITH coronin-1A deficiency (ortholog); Epidermodysplasia Verruciformis 4 (ortholog); Hyperglycinemia, Lactic Acidosis, and Seizures (ortholog); FOUND IN cytoplasm (ortholog); immunological synapse (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rho-related GTP-binding protein RhoH
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554437,227,751 - 7,264,821 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554437,227,751 - 7,269,984 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rhoh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554437,227,751 - 7,264,821 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554437,227,751 - 7,269,984 (-)NCBIChiLan1.0ChiLan1.0
RHOH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38440,191,080 - 40,246,967 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl440,191,011 - 40,246,967 (+)EnsemblGRCh38hg38GRCh38
GRCh37440,192,700 - 40,248,587 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36439,874,922 - 39,922,676 (+)NCBINCBI36Build 36hg18NCBI36
Build 34440,021,167 - 40,068,419NCBI
Celera440,637,435 - 40,685,176 (+)NCBICelera
Cytogenetic Map4p14NCBI
HuRef439,515,874 - 39,569,650 (+)NCBIHuRef
CHM1_1440,191,833 - 40,245,593 (+)NCBICHM1_1
T2T-CHM13v2.0440,161,181 - 40,217,041 (+)NCBIT2T-CHM13v2.0
Rhoh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39566,018,092 - 66,054,043 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl566,018,556 - 66,054,043 (+)EnsemblGRCm39 Ensembl
GRCm38565,860,742 - 65,896,700 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl565,861,213 - 65,896,700 (+)EnsemblGRCm38mm10GRCm38
MGSCv37566,254,808 - 66,287,939 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36566,140,350 - 66,175,835 (+)NCBIMGSCv36mm8
Celera563,159,997 - 63,193,217 (+)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map533.8NCBI
Rhoh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81442,694,860 - 42,725,690 (-)NCBIGRCr8
mRatBN7.21442,341,135 - 42,371,971 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1442,337,751 - 42,386,369 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1442,695,015 - 42,725,936 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01443,995,052 - 44,025,974 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01442,475,045 - 42,505,966 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01443,961,756 - 43,992,587 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1443,961,756 - 43,992,587 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01443,781,206 - 43,812,028 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41445,024,482 - 45,055,940 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11445,026,872 - 45,058,331 (-)NCBI
Celera1441,494,501 - 41,525,255 (-)NCBICelera
Cytogenetic Map14p11NCBI
RHOH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2340,381,386 - 40,430,592 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1440,573,329 - 40,622,540 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0434,517,487 - 34,569,934 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1440,374,816 - 40,420,753 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl440,419,549 - 40,420,124 (+)Ensemblpanpan1.1panPan2
RHOH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1372,272,446 - 72,277,015 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl372,276,418 - 72,276,993 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha374,822,104 - 74,825,439 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0373,040,298 - 73,043,633 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl373,039,977 - 73,089,743 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1372,309,276 - 72,312,610 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0372,459,426 - 72,462,761 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0372,843,539 - 72,846,874 (-)NCBIUU_Cfam_GSD_1.0
Rhoh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528538,574,902 - 38,615,064 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364827,689,371 - 7,723,321 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364827,721,815 - 7,723,395 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RHOH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl831,321,059 - 31,372,364 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1831,321,005 - 31,372,366 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2832,988,403 - 33,036,670 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RHOH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12710,061,316 - 10,109,124 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2710,062,014 - 10,062,589 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604756,429,868 - 56,477,900 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rhoh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476126,720,478 - 26,721,053 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476126,717,857 - 26,721,628 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000005593   ⟹   ENSCLAP00000005492
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554437,227,751 - 7,264,821 (-)Ensembl
RefSeq Acc Id: XM_005391959   ⟹   XP_005392016
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554437,227,751 - 7,264,821 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005391960   ⟹   XP_005392017
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554437,227,751 - 7,269,984 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005391961   ⟹   XP_005392018
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554437,227,751 - 7,248,770 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005391962   ⟹   XP_005392019
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554437,227,751 - 7,264,821 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013518115   ⟹   XP_013373569
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554437,227,751 - 7,264,821 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013518116   ⟹   XP_013373570
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554437,227,751 - 7,266,609 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005392017   ⟸   XM_005391960
- UniProtKB: A0A8C2UT87 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005392016   ⟸   XM_005391959
- UniProtKB: A0A8C2UT87 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005392019   ⟸   XM_005391962
- UniProtKB: A0A8C2UT87 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005392018   ⟸   XM_005391961
- UniProtKB: A0A8C2UT87 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013373570   ⟸   XM_013518116
- UniProtKB: A0A8C2UT87 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013373569   ⟸   XM_013518115
- UniProtKB: A0A8C2UT87 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000005492   ⟸   ENSCLAT00000005593


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003895 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000005593 ENTREZGENE
  ENSCLAT00000005593.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
  Small_GTPase_Rho UniProtKB/TrEMBL
NCBI Gene Rhoh ENTREZGENE
PANTHER PTHR24072 UniProtKB/TrEMBL
  RHO-RELATED GTP-BINDING PROTEIN RHOH UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8C2UT87 ENTREZGENE, UniProtKB/TrEMBL