Gene:	Grap2 ( Rattus norvegicus ) GRB2-related adaptor protein 2
Description:	exhibits protein binding and SH3/SH2 adaptor activity; involved in Ras protein signal transduction, antimicrobial humoral response (homolog)
Synonyms:	Grap2_predicted; MGC125066; GRB2-related adaptor protein 2 (predicted); LOC366962;  (details...)
ArrayIDs:	1391896_at;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: GRAP2     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Grap2     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Grap2 Rat Celera Assembly 7 108442874 - 108515048     RGSC genome assembly v3.4 7 118856130 - 118931148     Cytogenetic 7 q34     genome assembly 3.1 7 118882484 - 118965381 Mus musculus Grap2 Mouse genome assembly build 36.1 15 80453913 - 80480728     Cytogenetic 15 15 E2 Homo sapiens GRAP2 human genome assembly 22 38621585 - 38691884     Human genome assembly build 36.2 22 38627032 - 38697330     Cytogenetic 22 q13.2   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Gene Ontology protein binding (details...)
Cellular Component	Gene Ontology cytosol (details...)
External Links
Databases	DATABASE ID SOURCE SMART: SH2 IPI SMART: SH3 IPI PROSITE: SH3 IPI PROSITE: SH2 IPI UNIPARC: UPI00005C2E01 IPI UNIPARC: UPI0001B7ACD4 IPI HomoloGene Group ID: 21007 ENTREZGENE Germonline: 1307605 Pfam: SH3_1 IPI Pfam: SH2 IPI InterPro: SH3_domain. IPI InterPro: SH3_region. IPI InterPro: SH2. IPI IPI: IPI00949845 IPI IPI: IPI00370169 IPI Ensembl Protein: ENSRNOP00000058829 IPI Ensembl Protein: ENSRNOP00000024673 IPI Gene3D-CATH: SH2 IPI IMAGE_CLONE: IMAGE:7380480 IMAGE-MGC_LOAD Entrez Gene: Grap2 ENTREZGENE MGC_CLONE: MGC:125066 IMAGE-MGC_LOAD UniProt: Q3KR57_RAT IPI Ensembl Genes: ENSRNOG00000018316 IPI Superfamily-SCOP: SH3 IPI PRINTS: SH3DOMAIN. IPI PRINTS: SH2DOMAIN. IPI
Sequences	Nucleotide: BC105895 Get FASTA Search GEO Profiles Nucleotide: CH473950 Get FASTA Search GEO Profiles Nucleotide: NM_001034944 Get FASTA Search GEO Profiles (View all 3 Nucleotide Accessions) Protein: EDM15749 Get FASTA Protein: Q3KR57 Get FASTA Protein: AAI05896 Get FASTA Protein: EDM15748 Get FASTA Protein: NP_001030116 Get FASTA (View all 5 Protein Accessions)
Clusters	UniGene: 206804
References
Curated References	3 references in RGD related to Grap2
Other References	1 other references at PubMed related to Grap2
Database Information
RGD ID	1307605
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 06-DEC-05: Grap2 GRB2-related adaptor protein 2 Grap2_predicted GRB2-related adaptor protein 2 (predicted) APPROVED Symbol and Name updated 1559027 12-JAN-05: Grap2_predicted GRB2-related adaptor protein 2 (predicted) APPROVED Symbol and Name status set to approved 70820