Gene:	Rac2 ( Rattus norvegicus ) ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
Description:	exhibits GTPAse activity, protein binding (homolog); involved in actin cytoskeleton organization and biogeneis, bone resorption; associated with neutrophil immunodeficiency syndrome
Synonyms:	MGC105983; RAS-related C3 botulinum substrate 2; RAS-related C3 botulinum substrate 2 (predicted); LOC366957; Rac2_predicted;  (details...)
ArrayIDs:	6108103; 1372404_at; A_43_P15000; 6466034; 6445345; rc_AI010476_at; 6144822; A_44_P517012; 6137973; 6551662; GE15774; 6593902; A_44_P336727; 5995174;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: RAC2     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Rac2     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Rac2 Rat Celera Assembly 7 106454216 - 106466547     RGSC genome assembly v3.4 7 116520066 - 116532482     Cytogenetic 7 q34     genome assembly 3.1 7 116554295 - 116566712 Mus musculus Rac2 Mouse genome assembly build 36.1 15 78389599 - 78403213     Cytogenetic 15 15 E1 Homo sapiens RAC2 human genome assembly 22 35945811 - 35964805     Human genome assembly build 36.2 22 35951256 - 35970251     Cytogenetic 22 q13.1   View comparative maps:      NCBI MapViewer
Genome
View:
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Annotation
Molecular Function	Gene Ontology GTP binding,  protein binding,  nucleotide binding ...  (details...)
Biological Process	Gene Ontology chemotaxis,  cell projection assembly,  small GTPase mediated signal transduction ...  (details...)
Cellular Component	Gene Ontology intracellular,  cytoplasm,  membrane ...  (details...)
Disease	Ontology Abnormalities,  Syndrome (details...)
External Links
Databases	DATABASE ID SOURCE SMART: RHO IPI PROSITE: RHO IPI UNIPARC: UPI0000001881 IPI KEGG Report: rno:366957 ENTREZGENE HomoloGene Group ID: 55699 ENTREZGENE Germonline: 1307568 Pfam: Ras IPI KEGG Pathway: 04670 ENTREZGENE KEGG Pathway: 04010 ENTREZGENE KEGG Pathway: 04810 ENTREZGENE KEGG Pathway: 04510 ENTREZGENE KEGG Pathway: 04370 ENTREZGENE KEGG Pathway: 04666 ENTREZGENE KEGG Pathway: 05200 ENTREZGENE KEGG Pathway: 05212 ENTREZGENE KEGG Pathway: 04650 ENTREZGENE KEGG Pathway: 04662 ENTREZGENE KEGG Pathway: 04360 ENTREZGENE KEGG Pathway: 04520 ENTREZGENE KEGG Pathway: 04664 ENTREZGENE KEGG Pathway: 05210 ENTREZGENE KEGG Pathway: 04062 ENTREZGENE KEGG Pathway: 04310 ENTREZGENE InterPro: Small_GTP_bd. IPI InterPro: Ras_GTPase. IPI InterPro: GTPase_Rho. IPI InterPro: Ras. IPI Ensembl Protein: ENSRNOP00000009994 IPI IPI: IPI00358641 IPI Entrez Gene: Rac2 ENTREZGENE IMAGE_CLONE: IMAGE:7303112 IMAGE-MGC_LOAD MGC_CLONE: MGC:105983 IMAGE-MGC_LOAD UniProt: Q5U1Y2_RAT IPI Ensembl Genes: ENSRNOG00000007350 IPI TIGRFAMs: small_GTP IPI PRINTS: RASTRNSFRMNG. IPI
Sequences	Nucleotide: NM_001008384 Get FASTA Search GEO Profiles Nucleotide: CH473950 Get FASTA Search GEO Profiles Nucleotide: BC086399 Get FASTA Search GEO Profiles (View all 3 Nucleotide Accessions) Protein: EDM15859 Get FASTA Protein: AAH86399 Get FASTA Protein: Q5U1Y2 Get FASTA Protein: NP_001008385 Get FASTA (View all 4 Protein Accessions)
Clusters	UniGene: 2863
References
Curated References	5 references in RGD related to Rac2
Other References	3 other references at PubMed related to Rac2
Database Information
RGD ID	1307568
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 24-SEP-08: Rac2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) Rac2 RAS-related C3 botulinum substrate 2 APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863 06-DEC-05: Rac2 RAS-related C3 botulinum substrate 2 Rac2_predicted RAS-related C3 botulinum substrate 2 (predicted) APPROVED Symbol and Name updated 1559027 12-JAN-05: Rac2_predicted RAS-related C3 botulinum substrate 2 (predicted) APPROVED Symbol and Name status set to approved 70820