Tbc1d2b (TBC1 domain family, member 2B) - Rat Genome Database

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Gene: Tbc1d2b (TBC1 domain family, member 2B) Rattus norvegicus
Analyze
Symbol: Tbc1d2b
Name: TBC1 domain family, member 2B
RGD ID: 1307436
Description: Predicted to enable GTPase activator activity. Predicted to be involved in endocytosis. Predicted to be located in early endosome. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human TBC1D2B (TBC1 domain family member 2B); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC315880; RGD1307436; similar to KIAA1055 protein; TBC1 domain family member 2B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8899,626,019 - 99,694,669 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl899,626,019 - 99,694,637 (-)EnsemblGRCr8
mRatBN7.2890,746,220 - 90,814,867 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl890,746,233 - 90,814,832 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx896,426,206 - 96,494,417 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0894,625,630 - 94,693,850 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0892,473,463 - 92,541,855 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0897,577,551 - 97,647,072 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl897,577,565 - 97,647,072 (-)Ensemblrn6Rnor6.0
Rnor_5.0897,076,261 - 97,145,782 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4895,110,183 - 95,178,776 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera890,288,585 - 90,357,162 (-)NCBICelera
RGSC_v3.1895,132,610 - 95,204,190 (-)NCBI
Cytogenetic Map8q31NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17646400  


Genomics

Comparative Map Data
Tbc1d2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8899,626,019 - 99,694,669 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl899,626,019 - 99,694,637 (-)EnsemblGRCr8
mRatBN7.2890,746,220 - 90,814,867 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl890,746,233 - 90,814,832 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx896,426,206 - 96,494,417 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0894,625,630 - 94,693,850 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0892,473,463 - 92,541,855 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0897,577,551 - 97,647,072 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl897,577,565 - 97,647,072 (-)Ensemblrn6Rnor6.0
Rnor_5.0897,076,261 - 97,145,782 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4895,110,183 - 95,178,776 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera890,288,585 - 90,357,162 (-)NCBICelera
RGSC_v3.1895,132,610 - 95,204,190 (-)NCBI
Cytogenetic Map8q31NCBI
TBC1D2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381577,994,985 - 78,077,711 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1577,984,036 - 78,077,724 (-)Ensemblhg38GRCh38
GRCh371578,287,327 - 78,370,053 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361576,074,383 - 76,156,912 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1555,223,349 - 55,306,006 (-)NCBICelera
Cytogenetic Map15q24.3-q25.1NCBI
HuRef1555,044,906 - 55,127,542 (-)NCBIHuRef
CHM1_11578,405,273 - 78,487,934 (-)NCBICHM1_1
T2T-CHM13v2.01575,857,528 - 75,940,258 (-)NCBIT2T-CHM13v2.0
Tbc1d2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39990,084,100 - 90,152,861 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl990,084,080 - 90,152,857 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38990,202,047 - 90,270,772 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl990,202,027 - 90,270,804 (-)Ensemblmm10GRCm38
MGSCv37990,096,885 - 90,165,607 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36989,999,940 - 90,068,662 (-)NCBIMGSCv36mm8
Celera989,816,380 - 89,885,249 (-)NCBICelera
Cytogenetic Map9E3.1NCBI
cM Map947.48NCBI
Tbc1d2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955450582,223 - 641,876 (-)Ensembl
ChiLan1.0NW_004955450579,651 - 642,237 (-)NCBIChiLan1.0ChiLan1.0
TBC1D2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21667,207,937 - 67,291,319 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11571,373,488 - 71,456,845 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01556,923,368 - 57,006,708 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11575,890,620 - 75,972,066 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1575,874,740 - 75,972,020 (-)EnsemblpanPan2panpan1.1
TBC1D2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1358,225,099 - 58,285,519 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl358,226,184 - 58,286,204 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha360,886,603 - 60,948,432 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0358,662,997 - 58,725,973 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl358,662,997 - 58,709,209 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1358,159,522 - 58,223,334 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0358,367,731 - 58,429,546 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0358,716,864 - 58,783,875 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tbc1d2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640119,057,622 - 119,128,856 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647136,905,684 - 36,981,220 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647136,905,690 - 36,976,916 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBC1D2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl747,839,392 - 47,929,092 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1747,839,380 - 47,927,287 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2753,408,412 - 53,450,431 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TBC1D2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1265,276,348 - 5,358,247 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl265,276,533 - 5,360,373 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666048136,447,551 - 136,526,509 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbc1d2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248942,718,892 - 2,780,241 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248942,719,441 - 2,780,251 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tbc1d2b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1125,419,514 - 5,488,527 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tbc1d2b
400 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1228
Count of miRNA genes:331
Interacting mature miRNAs:451
Transcripts:ENSRNOT00000030645
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)863141536109261840Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)882352698127352698Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)862848139107848139Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)858337123103337123Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)862848139107848139Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)880768445125768445Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)862970527107970527Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)839106363103375781Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)862848139107848139Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)862848139107848139Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)862848139107848139Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)862848139107848139Rat
71120Niddm21Non-insulin dependent diabetes mellitus QTL 213.73blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)866992095111992095Rat
8693654Alc32Alcohol consumption QTL 3220.755drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)897492344116428905Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)860248093105248093Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)839106363103375781Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)839106258103375958Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)898145073122898010Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)862848139107848139Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)863404444108404444Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)855428416107963099Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)862963099107963099Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)880768445125768445Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)850763951107970527Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
724540Uae8Urinary albumin excretion QTL 85urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)839106258103375958Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)862982864107982864Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)880768445125768445Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)880768445125768445Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
BF387914  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2890,755,956 - 90,756,164 (+)MAPPERmRatBN7.2
Rnor_6.0897,587,288 - 97,587,495NCBIRnor6.0
Rnor_5.0897,085,998 - 97,086,205UniSTSRnor5.0
RGSC_v3.4895,119,906 - 95,120,113UniSTSRGSC3.4
Celera890,298,308 - 90,298,515UniSTS
RH 3.4 Map81013.0UniSTS
Cytogenetic Map8q31UniSTS
AI228491  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2890,752,632 - 90,752,739 (+)MAPPERmRatBN7.2
Rnor_6.0897,583,964 - 97,584,070NCBIRnor6.0
Rnor_5.0897,082,674 - 97,082,780UniSTSRnor5.0
RGSC_v3.4895,116,582 - 95,116,688UniSTSRGSC3.4
Celera890,294,984 - 90,295,090UniSTS
RH 3.4 Map81014.2UniSTS
Cytogenetic Map8q31UniSTS
RH131156  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2890,785,312 - 90,785,524 (+)MAPPERmRatBN7.2
Rnor_6.0897,616,831 - 97,617,042NCBIRnor6.0
Rnor_5.0897,115,541 - 97,115,752UniSTSRnor5.0
RGSC_v3.4895,149,259 - 95,149,470UniSTSRGSC3.4
Celera890,327,655 - 90,327,866UniSTS
RH 3.4 Map81015.6UniSTS
Cytogenetic Map8q31UniSTS
RH133286  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2890,746,372 - 90,746,563 (+)MAPPERmRatBN7.2
Rnor_6.0897,577,704 - 97,577,894NCBIRnor6.0
Rnor_5.0897,076,414 - 97,076,604UniSTSRnor5.0
RGSC_v3.4895,110,322 - 95,110,512UniSTSRGSC3.4
Celera890,288,724 - 90,288,914UniSTS
RH 3.4 Map81011.8UniSTS
Cytogenetic Map8q31UniSTS
RH137479  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2890,777,367 - 90,777,579 (+)MAPPERmRatBN7.2
Rnor_6.0897,608,887 - 97,609,098NCBIRnor6.0
Rnor_5.0897,107,597 - 97,107,808UniSTSRnor5.0
RGSC_v3.4895,141,315 - 95,141,526UniSTSRGSC3.4
Celera890,319,717 - 90,319,928UniSTS
Cytogenetic Map8q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000030645   ⟹   ENSRNOP00000029420
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl899,626,019 - 99,680,780 (-)Ensembl
mRatBN7.2 Ensembl890,746,234 - 90,814,832 (-)Ensembl
Rnor_6.0 Ensembl897,577,565 - 97,647,072 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098190   ⟹   ENSRNOP00000077731
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl890,746,233 - 90,801,926 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119718   ⟹   ENSRNOP00000093906
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl899,626,019 - 99,694,637 (-)Ensembl
mRatBN7.2 Ensembl890,746,233 - 90,814,799 (-)Ensembl
RefSeq Acc Id: NM_001413794   ⟹   NP_001400723
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8899,626,019 - 99,694,637 (-)NCBI
mRatBN7.2890,746,220 - 90,814,841 (-)NCBI
RefSeq Acc Id: XM_039081538   ⟹   XP_038937466
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8899,635,726 - 99,694,669 (-)NCBI
mRatBN7.2890,755,925 - 90,814,867 (-)NCBI
RefSeq Acc Id: XM_039081539   ⟹   XP_038937467
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8899,626,019 - 99,664,837 (-)NCBI
mRatBN7.2890,746,220 - 90,786,485 (-)NCBI
RefSeq Acc Id: XM_063265567   ⟹   XP_063121637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8899,626,019 - 99,694,669 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001400723 (Get FASTA)   NCBI Sequence Viewer  
  XP_038937466 (Get FASTA)   NCBI Sequence Viewer  
  XP_038937467 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121637 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL77556 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000029420.6
  ENSRNOP00000093906
  ENSRNOP00000093906.1
Ensembl Acc Id: ENSRNOP00000029420   ⟸   ENSRNOT00000030645
RefSeq Acc Id: XP_038937467   ⟸   XM_039081539
- Peptide Label: isoform X2
- UniProtKB: A6I221 (UniProtKB/TrEMBL),   D3ZAF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937466   ⟸   XM_039081538
- Peptide Label: isoform X1
- UniProtKB: A6I221 (UniProtKB/TrEMBL),   D3ZAF7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000077731   ⟸   ENSRNOT00000098190
Ensembl Acc Id: ENSRNOP00000093906   ⟸   ENSRNOT00000119718
RefSeq Acc Id: NP_001400723   ⟸   NM_001413794
- UniProtKB: A0A8I6ALB6 (UniProtKB/TrEMBL),   A6I221 (UniProtKB/TrEMBL),   D3ZAF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121637   ⟸   XM_063265567
- Peptide Label: isoform X3
- UniProtKB: A6I221 (UniProtKB/TrEMBL),   D3ZAF7 (UniProtKB/TrEMBL)
Protein Domains
PH   Rab-GAP TBC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZAF7-F1-model_v2 AlphaFold D3ZAF7 1-837 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696179
Promoter ID:EPDNEW_R6704
Type:initiation region
Name:Tbc1d2b_1
Description:TBC1 domain family, member 2B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0897,647,081 - 97,647,141EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307436 AgrOrtholog
BioCyc Gene G2FUF-29565 BioCyc
Ensembl Genes ENSRNOG00000014543 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030645.7 UniProtKB/TrEMBL
  ENSRNOT00000119718 ENTREZGENE
  ENSRNOT00000119718.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  putative rabgap domain of human tbc1 domain family member 14 like domains UniProtKB/TrEMBL
  Ypt/Rab-GAP domain of gyp1p, domain 3 UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  Rab-GTPase_TBC_sf UniProtKB/TrEMBL
  Rab_GAP_TBC_domain UniProtKB/TrEMBL
  RabGAP_TBC UniProtKB/TrEMBL
NCBI Gene 315880 ENTREZGENE
PANTHER RAB GTPASE-ACTIVATING PROTEIN 1-LIKE UniProtKB/TrEMBL
  TBC1 DOMAIN FAMILY MEMBER 2B UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
  TBC UniProtKB/TrEMBL
PhenoGen Tbc1d2b PhenoGen
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  TBC_RABGAP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014543 RatGTEx
SMART SM00233 UniProtKB/TrEMBL
  TBC UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  RabGAP_TBC UniProtKB/TrEMBL
UniProt A0A8I6ALB6 ENTREZGENE, UniProtKB/TrEMBL
  A6I221 ENTREZGENE, UniProtKB/TrEMBL
  D3ZAF7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Tbc1d2b  TBC1 domain family, member 2B  RGD1307436  similar to KIAA1055 protein  Symbol and Name updated 1299863 APPROVED
2005-12-06 RGD1307436  similar to KIAA1055 protein  RGD1307436_predicted  similar to KIAA1055 protein (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1307436_predicted  similar to KIAA1055 protein (predicted)  LOC315880_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC315880_predicted  similar to KIAA1055 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL