Tuba1c (tubulin, alpha 1C) - Rat Genome Database

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Gene: Tuba1c (tubulin, alpha 1C) Rattus norvegicus
Analyze
Symbol: Tuba1c
Name: tubulin, alpha 1C
RGD ID: 1307226
Description: Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Located in membrane raft. Orthologous to human TUBA1C (tubulin alpha 1c); PARTICIPATES IN phagocytosis pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: alpha-tubulin 6; LOC100909441; LOC300218; Tuba6; tubulin alpha-1C chain; tubulin alpha-1C chain-like; tubulin alpha-6 chain; tubulin, alpha 6
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87131,636,974 - 132,078,589 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7132,070,536 - 132,079,311 (+)EnsemblGRCr8
mRatBN7.27130,192,050 - 130,199,655 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX149,691,397 - 149,692,751 (-)EnsemblmRatBN7.2
mRatBN7.2 Ensembl7130,192,016 - 130,199,647 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7132,001,836 - 132,009,441 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07134,227,412 - 134,235,015 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07134,139,916 - 134,147,520 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07140,716,113 - 140,723,717 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7140,716,113 - 140,723,714 (+)Ensemblrn6Rnor6.0
Rnor_5.0X115,221,444 - 115,228,658 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47137,809,847 - 137,817,451 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7126,676,874 - 126,684,478 (+)NCBICelera
RGSC_v3.17137,886,283 - 137,893,885 (+)NCBI
Cytogenetic Map7q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-acetamidofluorene  (ISO)
2-amino-14,16-dimethyloctadecan-3-ol  (ISO)
2-butoxyethanol  (ISO)
2-nitrofluorene  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP)
buspirone  (EXP)
butyric acid  (ISO)
calcium silicate  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
diallyl trisulfide  (ISO)
dibenzo[a,l]pyrene  (ISO)
Dibutyl phosphate  (ISO)
diclofenac  (ISO)
diethylstilbestrol  (EXP,ISO)
dioxygen  (ISO)
diquat  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
flutamide  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glyphosate  (ISO)
GSK-J4  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
leflunomide  (ISO)
levofloxacin  (EXP)
methamphetamine  (ISO)
methapyrilene  (EXP)
miconazole  (ISO)
microcystin-LR  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
N-nitrosomorpholine  (EXP)
nefazodone  (EXP)
ochratoxin A  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorodecanoic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenanthrene  (ISO)
phenobarbital  (EXP)
phosgene  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
quartz  (ISO)
quercetin  (EXP)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
T-2 toxin  (EXP)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trimellitic anhydride  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
trovafloxacin  (EXP)
tungsten  (ISO)
tunicamycin  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vitamin E  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. A revised nomenclature for the human and rodent alpha-tubulin gene family. Khodiyar VK, etal., Genomics. 2007 May 31;.
3. Proteomic characterisation of neuronal sphingolipid-cholesterol microdomains: role in plasminogen activation. Ledesma MD, etal., Brain Res. 2003 Oct 10;987(1):107-16.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:19103752   PMID:19190083   PMID:21630459   PMID:22720776   PMID:25002582   PMID:25931508   PMID:29476059  


Genomics

Comparative Map Data
Tuba1c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87131,636,974 - 132,078,589 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7132,070,536 - 132,079,311 (+)EnsemblGRCr8
mRatBN7.27130,192,050 - 130,199,655 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX149,691,397 - 149,692,751 (-)EnsemblmRatBN7.2
mRatBN7.2 Ensembl7130,192,016 - 130,199,647 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7132,001,836 - 132,009,441 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07134,227,412 - 134,235,015 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07134,139,916 - 134,147,520 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07140,716,113 - 140,723,717 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7140,716,113 - 140,723,714 (+)Ensemblrn6Rnor6.0
Rnor_5.0X115,221,444 - 115,228,658 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47137,809,847 - 137,817,451 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7126,676,874 - 126,684,478 (+)NCBICelera
RGSC_v3.17137,886,283 - 137,893,885 (+)NCBI
Cytogenetic Map7q36NCBI
TUBA1C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381249,227,926 - 49,274,600 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1249,188,736 - 49,274,600 (+)Ensemblhg38GRCh38
GRCh371249,621,709 - 49,668,383 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361247,945,132 - 47,953,380 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1248,451,683 - 48,459,932 (+)NCBICelera
Cytogenetic Map12q13.12NCBI
HuRef1246,689,983 - 46,698,231 (+)NCBIHuRef
CHM1_11249,624,585 - 49,632,833 (+)NCBICHM1_1
T2T-CHM13v2.01249,190,111 - 49,236,791 (+)NCBIT2T-CHM13v2.0
Tuba1c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391598,927,772 - 98,935,986 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1598,927,772 - 98,935,991 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381599,029,891 - 99,038,105 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1599,029,891 - 99,038,110 (+)Ensemblmm10GRCm38
MGSCv371598,860,322 - 98,868,536 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361598,857,925 - 98,866,139 (+)NCBIMGSCv36mm8
Celera15101,191,004 - 101,222,463 (+)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1555.61NCBI
LOC102029877
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555008,083,239 - 8,092,137 (+)NCBIChiLan1.0ChiLan1.0
TUBA1C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21044,910,291 - 44,918,683 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11244,907,048 - 44,915,418 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01239,476,809 - 39,524,473 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11240,362,654 - 40,372,167 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1240,362,655 - 40,402,092 (-)EnsemblpanPan2panpan1.1
TUBA1C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1275,333,706 - 5,340,363 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2740,916,167 - 40,922,842 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0275,385,340 - 5,391,982 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl275,381,005 - 5,459,931 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1275,350,293 - 5,356,951 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0275,339,604 - 5,346,261 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02741,309,181 - 41,315,840 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101973343
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494566,131,026 - 66,138,661 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365127,026,102 - 7,033,883 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365127,026,107 - 7,033,804 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100127131
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1515,153,516 - 15,269,783 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2515,559,907 - 15,676,218 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103238262
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11145,494,973 - 45,502,786 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1145,494,919 - 45,503,300 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037200,627,195 - 200,635,303 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tuba1c
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11271,861,017 - 271,869,043 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tuba1c
3446 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:138
Count of miRNA genes:104
Interacting mature miRNAs:108
Transcripts:ENSRNOT00000020932
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)782111382132099989Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7121393075137014596Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7119280025135560836Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)793302009131686183Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7110725024135371468Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7115313999136544683Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)7116269196132020414Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat

Markers in Region
D5Arb10  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.17137,893,337 - 137,893,591RGD
Cytogenetic Map7q36UniSTS
PMC154451P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7q36UniSTS
AI060036  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27130,199,454 - 130,199,644 (+)MAPPERmRatBN7.2
Rnor_6.07140,723,517 - 140,723,706NCBIRnor6.0
Rnor_6.02199,203,541 - 199,203,730NCBIRnor6.0
Rnor_5.02218,687,312 - 218,687,501UniSTSRnor5.0
Rnor_5.0X115,228,458 - 115,228,647UniSTSRnor5.0
RGSC_v3.47137,817,251 - 137,817,440UniSTSRGSC3.4
Celera7126,684,278 - 126,684,467UniSTS
RH 3.4 Map71098.2UniSTS
Cytogenetic Map7q36UniSTS
RH78682  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.04209,800,159 - 209,800,341UniSTSRnor5.0
Rnor_5.02218,687,079 - 218,687,261UniSTSRnor5.0
Cytogenetic Map7q36UniSTS
Cytogenetic Map9q33UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
13 1 24 83 34 30 18 73 18 6 196 119 11 70 46 51 12 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001011995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC110690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC078829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000020932   ⟹   ENSRNOP00000020932
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7132,070,536 - 132,078,503 (+)Ensembl
mRatBN7.2 EnsemblX149,691,397 - 149,692,751 (-)Ensembl
Rnor_6.0 Ensembl2199,199,845 - 199,203,637 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000033450   ⟹   ENSRNOP00000068603
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7130,192,016 - 130,199,647 (+)Ensembl
Rnor_6.0 Ensembl7140,716,113 - 140,723,714 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000120720   ⟹   ENSRNOP00000109253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7132,070,962 - 132,079,311 (+)Ensembl
RefSeq Acc Id: NM_001011995   ⟹   NP_001011995
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87132,070,984 - 132,078,589 (+)NCBI
mRatBN7.27130,192,050 - 130,199,655 (+)NCBI
Rnor_6.07140,716,113 - 140,723,717 (+)NCBI
Rnor_5.0X115,221,444 - 115,228,658 (+)NCBI
RGSC_v3.47137,809,847 - 137,817,451 (+)RGD
Celera7126,676,874 - 126,684,478 (+)RGD
Sequence:
RefSeq Acc Id: XM_063263380   ⟹   XP_063119450
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87131,637,018 - 132,078,589 (+)NCBI
RefSeq Acc Id: XM_063263381   ⟹   XP_063119451
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87131,637,019 - 132,078,589 (+)NCBI
RefSeq Acc Id: XM_063263382   ⟹   XP_063119452
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87131,637,016 - 132,078,589 (+)NCBI
RefSeq Acc Id: XM_063263383   ⟹   XP_063119453
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87131,636,979 - 132,078,589 (+)NCBI
RefSeq Acc Id: XM_063263384   ⟹   XP_063119454
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87131,636,974 - 132,078,589 (+)NCBI
RefSeq Acc Id: NP_001011995   ⟸   NM_001011995
- UniProtKB: Q6AYZ1 (UniProtKB/Swiss-Prot),   A6KCD2 (UniProtKB/TrEMBL),   A0A8I6ALV8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000068603   ⟸   ENSRNOT00000033450
Ensembl Acc Id: ENSRNOP00000020932   ⟸   ENSRNOT00000020932
RefSeq Acc Id: XP_063119454   ⟸   XM_063263384
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ALV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119453   ⟸   XM_063263383
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ALV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119452   ⟸   XM_063263382
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ALV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119450   ⟸   XM_063263380
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ALV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119451   ⟸   XM_063263381
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ALV8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000109253   ⟸   ENSRNOT00000120720
Protein Domains
Tubulin/FtsZ 2-layer sandwich   Tubulin/FtsZ GTPase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0H2UHM7-F1-model_v2 AlphaFold A0A0H2UHM7 1-448 view protein structure
AF-Q6AYZ1-F1-model_v2 AlphaFold Q6AYZ1 1-449 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695637
Promoter ID:EPDNEW_R6162
Type:single initiation site
Name:Tuba1c_1
Description:tubulin, alpha 1C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07140,716,092 - 140,716,152EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307226 AgrOrtholog
BioCyc Gene G2FUF-32091 BioCyc
Ensembl Genes ENSRNOG00000015544 Ensembl
  ENSRNOG00000021438 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000075184 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000020932 ENTREZGENE
  ENSRNOT00000033450.4 UniProtKB/Swiss-Prot
  ENSRNOT00000120720 ENTREZGENE
Gene3D-CATH 1.10.287.600 UniProtKB/Swiss-Prot
  3.30.1330.20 UniProtKB/Swiss-Prot
  3.40.50.1440 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7112420 IMAGE-MGC_LOAD
InterPro Alpha_tubulin UniProtKB/Swiss-Prot
  Tub_FtsZ_C UniProtKB/Swiss-Prot
  Tubulin UniProtKB/Swiss-Prot
  Tubulin/FtsZ_2-layer-sand-dom UniProtKB/Swiss-Prot
  Tubulin/FtsZ_C_sf UniProtKB/Swiss-Prot
  Tubulin/FtsZ_GTPase_sf UniProtKB/Swiss-Prot
  Tubulin_C UniProtKB/Swiss-Prot
  Tubulin_CS UniProtKB/Swiss-Prot
  Tubulin_FtsZ_GTPase UniProtKB/Swiss-Prot
KEGG Report rno:300218 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93445 IMAGE-MGC_LOAD
NCBI Gene 300218 ENTREZGENE
PANTHER PTHR11588 UniProtKB/Swiss-Prot
Pfam Tubulin UniProtKB/Swiss-Prot
  Tubulin_C UniProtKB/Swiss-Prot
PhenoGen Tuba1c PhenoGen
PRINTS ALPHATUBULIN UniProtKB/Swiss-Prot
  TUBULIN UniProtKB/Swiss-Prot
PROSITE TUBULIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000015544 RatGTEx
  ENSRNOG00000021438 RatGTEx
  ENSRNOG00000075184 RatGTEx
SMART Tubulin UniProtKB/Swiss-Prot
  Tubulin_C UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52490 UniProtKB/Swiss-Prot
  SSF55307 UniProtKB/Swiss-Prot
UniProt A0A0H2UHM7_RAT UniProtKB/TrEMBL
  A0A8I6ALV8 ENTREZGENE
  A6KCD2 ENTREZGENE, UniProtKB/TrEMBL
  Q6AYZ1 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Tuba1c  tubulin, alpha 1C  LOC100909441  tubulin alpha-1C chain-like  Data merged from RGD:6503589 737654 PROVISIONAL
2012-07-05 LOC100909441  tubulin alpha-1C chain-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2007-05-17 Tuba1c  tubulin, alpha 1C  Tuba6  tubulin, alpha 6  Symbol and Name updated 1624988 APPROVED
2005-12-06 Tuba6  tubulin, alpha 6  Tuba6_predicted  tubulin, alpha 6 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Tuba6_predicted  tubulin, alpha 6 (predicted)      Symbol and Name status set to approved 70820 APPROVED