Pbx3 (PBX homeobox 3) - Rat Genome Database

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Gene: Pbx3 (PBX homeobox 3) Rattus norvegicus
Analyze
Symbol: Pbx3
Name: PBX homeobox 3
RGD ID: 1307198
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including eye development; nervous system development; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including adult locomotory behavior; dorsal spinal cord development; and regulation of respiratory gaseous exchange by nervous system process. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Orthologous to human PBX3 (PBX homeobox 3); INTERACTS WITH 17beta-estradiol; 3,4-methylenedioxymethamphetamine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC102551296; LOC311876; pre B-cell leukemia transcription factor 3; pre-B-cell leukemia homeobox 3; pre-B-cell leukemia transcription factor 3; pre-B-cell leukemia transcription factor 3-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8337,886,241 - 38,079,956 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl337,886,687 - 38,079,895 (-)EnsemblGRCr8
mRatBN7.2317,488,691 - 17,682,412 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl317,488,693 - 17,682,791 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx320,557,559 - 20,750,825 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0329,142,610 - 29,335,881 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0327,395,628 - 27,589,698 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0313,241,031 - 13,436,084 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl313,182,024 - 13,525,983 (-)Ensemblrn6Rnor6.0
Rnor_5.0318,569,183 - 18,763,413 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4313,200,261 - 13,405,859 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera312,211,343 - 12,404,425 (-)NCBICelera
RGSC_v3.1313,096,449 - 13,311,087 (-)NCBI
Cytogenetic Map3p11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
arsenous acid  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP)
cocaine  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
hexadecanoic acid  (ISO)
indometacin  (ISO)
ketamine  (EXP)
L-methionine  (ISO)
lead diacetate  (ISO)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
toluene  (EXP)
topotecan  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
trovafloxacin  (ISO)
uranium atom  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Non-synonymous variants in pre-B cell leukemia homeobox (PBX) genes are associated with congenital heart defects. Arrington CB, etal., Eur J Med Genet. 2012 Apr;55(4):235-7. doi: 10.1016/j.ejmg.2012.02.002. Epub 2012 Feb 23.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Downregulation of lncRNA-HEIH curbs esophageal squamous cell carcinoma progression by modulating miR-4458/PBX3. Wang D, etal., Thorac Cancer. 2020 Jul;11(7):1963-1971. doi: 10.1111/1759-7714.13489. Epub 2020 May 25.
Additional References at PubMed
PMID:10381567   PMID:10842069   PMID:15466398   PMID:15527896   PMID:16847320   PMID:18155191   PMID:33389498  


Genomics

Comparative Map Data
Pbx3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8337,886,241 - 38,079,956 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl337,886,687 - 38,079,895 (-)EnsemblGRCr8
mRatBN7.2317,488,691 - 17,682,412 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl317,488,693 - 17,682,791 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx320,557,559 - 20,750,825 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0329,142,610 - 29,335,881 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0327,395,628 - 27,589,698 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0313,241,031 - 13,436,084 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl313,182,024 - 13,525,983 (-)Ensemblrn6Rnor6.0
Rnor_5.0318,569,183 - 18,763,413 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4313,200,261 - 13,405,859 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera312,211,343 - 12,404,425 (-)NCBICelera
RGSC_v3.1313,096,449 - 13,311,087 (-)NCBI
Cytogenetic Map3p11NCBI
PBX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389125,747,373 - 125,967,377 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9125,746,737 - 125,967,377 (+)Ensemblhg38GRCh38
GRCh379128,509,652 - 128,729,656 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369127,549,487 - 127,769,477 (+)NCBIBuild 36Build 36hg18NCBI36
Build 349125,589,286 - 125,808,921NCBI
Celera999,158,741 - 99,384,104 (+)NCBICelera
Cytogenetic Map9q33.3NCBI
HuRef998,122,353 - 98,347,071 (+)NCBIHuRef
CHM1_19128,660,292 - 128,880,307 (+)NCBICHM1_1
T2T-CHM13v2.09137,947,324 - 138,172,756 (+)NCBIT2T-CHM13v2.0
Pbx3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39234,061,469 - 34,264,168 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl234,061,469 - 34,263,154 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38234,171,457 - 34,372,045 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl234,171,457 - 34,373,142 (-)Ensemblmm10GRCm38
MGSCv37234,027,429 - 34,227,556 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36233,993,918 - 34,194,045 (-)NCBIMGSCv36mm8
Celera233,869,694 - 34,069,148 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.84NCBI
Pbx3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554192,419,029 - 2,627,607 (-)Ensembl
ChiLan1.0NW_0049554192,419,081 - 2,624,299 (-)NCBIChiLan1.0ChiLan1.0
PBX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21113,387,710 - 13,609,960 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1913,390,056 - 13,612,138 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0996,867,140 - 97,089,205 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19125,379,110 - 125,599,634 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9125,379,489 - 125,598,178 (+)EnsemblpanPan2panpan1.1
PBX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1957,198,531 - 57,429,820 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl957,199,812 - 57,429,811 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha956,399,623 - 56,630,129 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0958,119,354 - 58,350,418 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl958,119,626 - 58,337,153 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1956,877,592 - 57,108,518 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0957,193,844 - 57,424,560 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0957,284,917 - 57,516,098 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pbx3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947194,010,931 - 194,218,090 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648713,779,454 - 13,987,722 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648713,779,999 - 13,986,617 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PBX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1266,382,640 - 266,610,640 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11266,383,311 - 266,610,646 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21300,208,202 - 300,433,688 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PBX3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11212,174,407 - 12,400,184 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660793,721,016 - 3,948,699 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pbx3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247609,352,563 - 9,553,984 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247609,352,759 - 9,555,211 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Pbx3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v151,260,615 - 1,453,402 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pbx3
1475 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:388
Count of miRNA genes:213
Interacting mature miRNAs:246
Transcripts:ENSRNOT00000029600
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32905627547904329Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
11528620Bss113Bone structure and strength QTL 1139.752e-10femur morphology trait (VT:0000559)femoral neck width (CMO:0001695)33688834239639105Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)body weight (CMO:0000012)33777225855937853Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)32862533967641995Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)33540319997383526Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)3612543751125437Rat
8693641Alc30Alcohol consumption QTL 3020.739drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)33083238444921701Rat
1558657Cm43Cardiac mass QTL 436.63e-08heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31527234860272348Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33642511681425116Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)33779691953640235Rat
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)33779691982796919Rat
10450811Scl73Serum cholesterol level QTL 734.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat
10450808Scl72Serum cholesterol level QTL 724.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10450806Scl71Serum cholesterol level QTL 715.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)336721849110333156Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)33736373482363734Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3655634751556347Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)33610140381101403Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)32905627547904329Rat
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)33779691947904329Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)33779691959119581Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat

Markers in Region
D3Chm7  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2317,600,282 - 17,600,509 (+)MAPPERmRatBN7.2
Rnor_6.0313,352,601 - 13,352,827NCBIRnor6.0
Rnor_5.0318,680,823 - 18,681,049UniSTSRnor5.0
RGSC_v3.4313,312,546 - 13,312,772UniSTSRGSC3.4
RGSC_v3.4313,312,545 - 13,312,772RGDRGSC3.4
Celera312,322,409 - 12,322,635UniSTS
Cytogenetic Map3p11UniSTS
RH133967  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2317,672,538 - 17,672,744 (+)MAPPERmRatBN7.2
Rnor_6.0314,159,612 - 14,159,817NCBIRnor6.0
Rnor_6.0313,426,211 - 13,426,416NCBIRnor6.0
Rnor_5.0318,753,576 - 18,753,781UniSTSRnor5.0
Rnor_5.0319,478,517 - 19,478,722UniSTSRnor5.0
RGSC_v3.4313,396,073 - 13,396,278UniSTSRGSC3.4
Celera312,394,614 - 12,394,819UniSTS
Cytogenetic Map3p11UniSTS
G07093  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2317,489,211 - 17,489,318 (+)MAPPERmRatBN7.2
Rnor_6.0313,241,552 - 13,241,658NCBIRnor6.0
Rnor_5.0318,569,704 - 18,569,810UniSTSRnor5.0
RGSC_v3.4313,200,336 - 13,200,442UniSTSRGSC3.4
Celera312,211,418 - 12,211,524UniSTS
Cytogenetic Map3p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 355 192 11 143 80 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000029600   ⟹   ENSRNOP00000029846
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl317,488,693 - 17,682,303 (-)Ensembl
Rnor_6.0 Ensembl313,240,999 - 13,435,979 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000082036   ⟹   ENSRNOP00000075035
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl337,890,623 - 38,079,895 (-)Ensembl
mRatBN7.2 Ensembl317,494,240 - 17,682,350 (-)Ensembl
Rnor_6.0 Ensembl313,182,024 - 13,525,983 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096937   ⟹   ENSRNOP00000087541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl337,886,687 - 38,079,895 (-)Ensembl
mRatBN7.2 Ensembl317,488,954 - 17,682,323 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111698   ⟹   ENSRNOP00000082471
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl317,488,693 - 17,682,791 (-)Ensembl
RefSeq Acc Id: NM_001107834   ⟹   NP_001101304
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8337,886,687 - 38,079,895 (-)NCBI
mRatBN7.2317,489,137 - 17,682,350 (-)NCBI
Rnor_6.0313,241,477 - 13,436,022 (-)NCBI
Rnor_5.0318,569,183 - 18,763,413 (-)NCBI
RGSC_v3.4313,200,261 - 13,405,859 (-)RGD
Celera312,211,343 - 12,404,425 (-)RGD
Sequence:
RefSeq Acc Id: XM_006233975   ⟹   XP_006234037
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8337,887,688 - 38,079,956 (-)NCBI
mRatBN7.2317,489,117 - 17,682,412 (-)NCBI
Rnor_6.0313,241,031 - 13,436,084 (-)NCBI
Rnor_5.0318,569,183 - 18,763,413 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105260   ⟹   XP_038961188
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8337,886,241 - 38,079,715 (-)NCBI
mRatBN7.2317,488,691 - 17,682,153 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001101304 (Get FASTA)   NCBI Sequence Viewer  
  XP_006234037 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961188 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL93176 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000075035
  ENSRNOP00000075035.3
  ENSRNOP00000087541
  ENSRNOP00000087541.2
RefSeq Acc Id: NP_001101304   ⟸   NM_001107834
- UniProtKB: D4AB31 (UniProtKB/TrEMBL),   A6JUC0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234037   ⟸   XM_006233975
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AGR6 (UniProtKB/TrEMBL),   A0A0G2K9K8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075035   ⟸   ENSRNOT00000082036
Ensembl Acc Id: ENSRNOP00000029846   ⟸   ENSRNOT00000029600
RefSeq Acc Id: XP_038961188   ⟸   XM_039105260
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000082471   ⟸   ENSRNOT00000111698
Ensembl Acc Id: ENSRNOP00000087541   ⟸   ENSRNOT00000096937
Protein Domains
Homeobox   PBC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AB31-F1-model_v2 AlphaFold D4AB31 1-434 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692003
Promoter ID:EPDNEW_R2528
Type:single initiation site
Name:Pbx3_1
Description:PBX homeobox 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0313,436,058 - 13,436,118EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307198 AgrOrtholog
BioCyc Gene G2FUF-50090 BioCyc
Ensembl Genes ENSRNOG00000022162 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000082036 ENTREZGENE
  ENSRNOT00000082036.3 UniProtKB/TrEMBL
  ENSRNOT00000096937 ENTREZGENE
  ENSRNOT00000096937.2 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_KN_domain UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
  PBX UniProtKB/TrEMBL
  TALE_homeobox UniProtKB/TrEMBL
KEGG Report rno:311876 UniProtKB/TrEMBL
NCBI Gene 311876 ENTREZGENE
PANTHER HOMEOBOX PROTEIN TRANSCRIPTION FACTORS UniProtKB/TrEMBL
Pfam Homeobox_KN UniProtKB/TrEMBL
  PBC UniProtKB/TrEMBL
PhenoGen Pbx3 PhenoGen
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
  PBC UniProtKB/TrEMBL
RatGTEx ENSRNOG00000022162 RatGTEx
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP Homeodomain_like UniProtKB/TrEMBL
UniProt A0A0G2K9K8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AGR6 ENTREZGENE, UniProtKB/TrEMBL
  A6JUC0 ENTREZGENE, UniProtKB/TrEMBL
  D4AB31 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Pbx3  PBX homeobox 3  LOC102551296  pre-B-cell leukemia transcription factor 3-like  Data merged from RGD:7560948 737654 PROVISIONAL
2016-05-26 Pbx3  PBX homeobox 3  Pbx3  pre-B-cell leukemia homeobox 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-17 LOC102551296  pre-B-cell leukemia transcription factor 3-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-10-30 Pbx3  pre-B-cell leukemia homeobox 3  Pbx3  pre B-cell leukemia transcription factor 3   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Pbx3  pre B-cell leukemia transcription factor 3   Pbx3_predicted  pre B-cell leukemia transcription factor 3 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Pbx3_predicted  pre B-cell leukemia transcription factor 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED