Pls1 (plastin 1) - Rat Genome Database

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Gene: Pls1 (plastin 1) Rattus norvegicus
Analyze
Symbol: Pls1
Name: plastin 1
RGD ID: 1307142
Description: Predicted to enable actin filament binding activity. Predicted to be involved in several processes, including actin filament organization; inner ear receptor cell stereocilium organization; and intestinal D-glucose absorption. Predicted to act upstream of or within terminal web assembly. Predicted to be located in several cellular components, including brush border; stereocilium; and terminal web. Predicted to be active in actin filament; actin filament bundle; and cytoplasm. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 76. Orthologous to human PLS1 (plastin 1); PARTICIPATES IN auditory mechanotransduction pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC315926; MGC189074; plastin 1 (I isoform); plastin-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88105,196,312 - 105,306,252 (-)NCBIGRCr8
mRatBN7.2896,316,703 - 96,426,592 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl896,317,849 - 96,385,195 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8101,983,678 - 102,015,932 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08100,182,931 - 100,215,183 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0898,021,875 - 98,054,127 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08103,557,361 - 103,659,625 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8103,557,364 - 103,608,913 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08103,008,357 - 103,110,153 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48100,825,543 - 100,858,153 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18100,845,099 - 100,913,858 (-)NCBI
Celera895,763,631 - 95,795,453 (-)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-benzofuran  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
acrolein  (ISO)
afimoxifene  (ISO)
alpha-pinene  (ISO)
alpha-Zearalanol  (EXP)
amiodarone  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
Butylbenzyl phthalate  (EXP)
caffeine  (ISO)
carbamazepine  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
diethyl phthalate  (EXP)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
glafenine  (EXP)
GW 4064  (ISO)
inulin  (ISO)
ivermectin  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Monobutylphthalate  (ISO)
N-nitrosodiethylamine  (ISO)
naphthalene-1,5-diamine  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
temozolomide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
tributylstannane  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Review series: The cell biology of hearing. Schwander M, etal., J Cell Biol. 2010 Jul 12;190(1):9-20. doi: 10.1083/jcb.201001138.
Additional References at PubMed
PMID:7655078   PMID:12477932   PMID:19056867   PMID:19321664   PMID:22114352   PMID:23376485  


Genomics

Comparative Map Data
Pls1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88105,196,312 - 105,306,252 (-)NCBIGRCr8
mRatBN7.2896,316,703 - 96,426,592 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl896,317,849 - 96,385,195 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8101,983,678 - 102,015,932 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08100,182,931 - 100,215,183 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0898,021,875 - 98,054,127 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08103,557,361 - 103,659,625 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8103,557,364 - 103,608,913 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08103,008,357 - 103,110,153 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48100,825,543 - 100,858,153 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18100,845,099 - 100,913,858 (-)NCBI
Celera895,763,631 - 95,795,453 (-)NCBICelera
Cytogenetic Map8q31NCBI
PLS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383142,596,393 - 142,713,664 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3142,596,393 - 142,713,664 (+)EnsemblGRCh38hg38GRCh38
GRCh373142,315,235 - 142,432,506 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363143,825,034 - 143,915,191 (+)NCBINCBI36Build 36hg18NCBI36
Build 343143,825,041 - 143,915,199NCBI
Celera3140,738,741 - 140,856,000 (+)NCBICelera
Cytogenetic Map3q23NCBI
HuRef3139,687,922 - 139,805,221 (+)NCBIHuRef
CHM1_13142,278,265 - 142,395,516 (+)NCBICHM1_1
T2T-CHM13v2.03145,343,653 - 145,460,901 (+)NCBIT2T-CHM13v2.0
Pls1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39995,634,695 - 95,727,359 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl995,634,695 - 95,727,364 (-)EnsemblGRCm39 Ensembl
GRCm38995,752,642 - 95,845,306 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl995,752,642 - 95,845,311 (-)EnsemblGRCm38mm10GRCm38
MGSCv37995,653,061 - 95,745,698 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36995,563,391 - 95,654,612 (-)NCBIMGSCv36mm8
Celera995,319,770 - 95,411,700 (-)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map950.22NCBI
Pls1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555083,213,646 - 3,260,554 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555083,215,304 - 3,324,240 (-)NCBIChiLan1.0ChiLan1.0
PLS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22140,490,165 - 140,623,025 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13140,494,897 - 140,627,757 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03139,629,825 - 139,747,080 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13147,221,909 - 147,338,600 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3147,289,205 - 147,338,600 (+)Ensemblpanpan1.1panPan2
PLS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12338,243,631 - 38,347,195 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2338,243,024 - 38,347,202 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2338,170,597 - 38,273,260 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02338,775,761 - 38,879,245 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2338,775,186 - 38,879,252 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12338,457,792 - 38,561,305 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02338,534,253 - 38,637,869 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02338,778,573 - 38,881,960 (+)NCBIUU_Cfam_GSD_1.0
Pls1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560277,466,080 - 77,583,189 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365404,205,844 - 4,323,120 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365404,205,871 - 4,323,121 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1383,308,007 - 83,434,128 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11383,307,692 - 83,434,133 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PLS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11547,919,807 - 48,031,158 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1547,919,823 - 48,003,805 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604120,854,232 - 20,965,494 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pls1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473019,163,783 - 19,302,222 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473019,164,360 - 19,302,369 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pls1
565 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:47
Count of miRNA genes:39
Interacting mature miRNAs:46
Transcripts:ENSRNOT00000013209
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)84329616998968765Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)854259986100382532Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)84329616998968765Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)84329616998968765Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)84329616998968765Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)84329616998968765Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)84329616998968765Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
8693654Alc32Alcohol consumption QTL 3220.755drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)888612425107550209Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)85404374498968765Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)84653172299083736Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)85423764499103503Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat

Markers in Region
RH134294  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2896,318,132 - 96,318,327 (+)MAPPERmRatBN7.2
Rnor_6.08103,558,789 - 103,558,983NCBIRnor6.0
Rnor_5.08103,009,785 - 103,009,979UniSTSRnor5.0
RGSC_v3.48100,825,828 - 100,826,022UniSTSRGSC3.4
Celera895,763,916 - 95,764,110UniSTS
RH 3.4 Map81056.7UniSTS
Cytogenetic Map8q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 8 48 113 91 90 59 25 59 6 214 93 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000013209   ⟹   ENSRNOP00000013209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl896,317,849 - 96,385,195 (-)Ensembl
Rnor_6.0 Ensembl8103,557,364 - 103,608,913 (-)Ensembl
RefSeq Acc Id: NM_001108178   ⟹   NP_001101648
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88105,197,454 - 105,229,339 (-)NCBI
mRatBN7.2896,317,848 - 96,349,733 (-)NCBI
Rnor_6.08103,558,504 - 103,596,278 (-)NCBI
Rnor_5.08103,008,357 - 103,110,153 (-)NCBI
RGSC_v3.48100,825,543 - 100,858,153 (-)RGD
Celera895,763,631 - 95,795,453 (-)RGD
Sequence:
RefSeq Acc Id: XM_006243574   ⟹   XP_006243636
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88105,196,312 - 105,292,487 (-)NCBI
mRatBN7.2896,316,703 - 96,412,828 (-)NCBI
Rnor_6.08103,557,361 - 103,659,625 (-)NCBI
Rnor_5.08103,008,357 - 103,110,153 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039081542   ⟹   XP_038937470
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88105,196,312 - 105,306,252 (-)NCBI
mRatBN7.2896,316,705 - 96,426,592 (-)NCBI
RefSeq Acc Id: XM_063265574   ⟹   XP_063121644
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88105,196,312 - 105,264,488 (-)NCBI
RefSeq Acc Id: NP_001101648   ⟸   NM_001108178
- Sequence:
RefSeq Acc Id: XP_006243636   ⟸   XM_006243574
- Peptide Label: isoform X1
- UniProtKB: A0A0G2QC04 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000013209   ⟸   ENSRNOT00000013209
RefSeq Acc Id: XP_038937470   ⟸   XM_039081542
- Peptide Label: isoform X1
- UniProtKB: A0A0G2QC04 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121644   ⟸   XM_063265574
- Peptide Label: isoform X1
- UniProtKB: A0A0G2QC04 (UniProtKB/TrEMBL)
Protein Domains
Calponin-homology (CH)   EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2QC04-F1-model_v2 AlphaFold A0A0G2QC04 1-630 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696188
Promoter ID:EPDNEW_R6712
Type:initiation region
Name:Pls1_1
Description:plastin 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08103,608,975 - 103,609,035EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307142 AgrOrtholog
BioCyc Gene G2FUF-29477 BioCyc
Ensembl Genes ENSRNOG00000009945 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013209.8 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro Actinin_actin-bd_CS UniProtKB/TrEMBL
  Calponin-like_dom_sf UniProtKB/TrEMBL
  CH-domain UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  Fimbrin/Plastin UniProtKB/TrEMBL
KEGG Report rno:315926 UniProtKB/TrEMBL
NCBI Gene 315926 ENTREZGENE
PANTHER PTHR19961 UniProtKB/TrEMBL
  PTHR19961:SF27 UniProtKB/TrEMBL
Pfam EF-hand_7 UniProtKB/TrEMBL
  PF00307 UniProtKB/TrEMBL
PharmGKB PLS1 RGD
PhenoGen Pls1 PhenoGen
PROSITE ACTININ_1 UniProtKB/TrEMBL
  ACTININ_2 UniProtKB/TrEMBL
  EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  PS50021 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009945 RatGTEx
SMART EFh UniProtKB/TrEMBL
  SM00033 UniProtKB/TrEMBL
Superfamily-SCOP Calponin-homology UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
UniProt A0A0G2QC04 ENTREZGENE, UniProtKB/TrEMBL
  B5DEY0_RAT UniProtKB/TrEMBL
UniProt Secondary F1LQQ6 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Pls1  plastin 1  Pls1  plastin 1 (I isoform)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Pls1  plastin 1 (I isoform)   Pls1_predicted  plastin 1 (I isoform) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Pls1_predicted  plastin 1 (I isoform) (predicted)      Symbol and Name status set to approved 70820 APPROVED