PLS1 (plastin 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: PLS1 (plastin 1) Pan paniscus
Analyze
Symbol: PLS1
Name: plastin 1
RGD ID: 11741410
Description: ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); calcium ion binding (inferred); INVOLVED IN microvillus assembly (ortholog); terminal web assembly (ortholog); PARTICIPATES IN auditory mechanotransduction pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness (ortholog); autosomal dominant nonsyndromic deafness 76 (ortholog); genetic disease (ortholog); FOUND IN actin filament (inferred); actin filament bundle (inferred); brush border (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: plastin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22140,490,165 - 140,623,025 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13140,494,897 - 140,627,757 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03139,629,825 - 139,747,080 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13147,221,909 - 147,338,600 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3147,289,205 - 147,338,600 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PLS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22140,490,165 - 140,623,025 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13140,494,897 - 140,627,757 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03139,629,825 - 139,747,080 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13147,221,909 - 147,338,600 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3147,289,205 - 147,338,600 (+)Ensemblpanpan1.1panPan2
PLS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383142,596,393 - 142,713,664 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3142,596,393 - 142,713,664 (+)EnsemblGRCh38hg38GRCh38
GRCh373142,315,235 - 142,432,506 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363143,825,034 - 143,915,191 (+)NCBINCBI36Build 36hg18NCBI36
Build 343143,825,041 - 143,915,199NCBI
Celera3140,738,741 - 140,856,000 (+)NCBICelera
Cytogenetic Map3q23NCBI
HuRef3139,687,922 - 139,805,221 (+)NCBIHuRef
CHM1_13142,278,265 - 142,395,516 (+)NCBICHM1_1
T2T-CHM13v2.03145,343,653 - 145,460,901 (+)NCBIT2T-CHM13v2.0
Pls1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39995,634,695 - 95,727,359 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl995,634,695 - 95,727,364 (-)EnsemblGRCm39 Ensembl
GRCm38995,752,642 - 95,845,306 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl995,752,642 - 95,845,311 (-)EnsemblGRCm38mm10GRCm38
MGSCv37995,653,061 - 95,745,698 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36995,563,391 - 95,654,612 (-)NCBIMGSCv36mm8
Celera995,319,770 - 95,411,700 (-)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map950.22NCBI
Pls1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88105,196,312 - 105,306,252 (-)NCBIGRCr8
mRatBN7.2896,316,703 - 96,426,592 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl896,317,849 - 96,385,195 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8101,983,678 - 102,015,932 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08100,182,931 - 100,215,183 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0898,021,875 - 98,054,127 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08103,557,361 - 103,659,625 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8103,557,364 - 103,608,913 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08103,008,357 - 103,110,153 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48100,825,543 - 100,858,153 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18100,845,099 - 100,913,858 (-)NCBI
Celera895,763,631 - 95,795,453 (-)NCBICelera
Cytogenetic Map8q31NCBI
Pls1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555083,213,646 - 3,260,554 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555083,215,304 - 3,324,240 (-)NCBIChiLan1.0ChiLan1.0
PLS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12338,243,631 - 38,347,195 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2338,243,024 - 38,347,202 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2338,170,597 - 38,273,260 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02338,775,761 - 38,879,245 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2338,775,186 - 38,879,252 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12338,457,792 - 38,561,305 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02338,534,253 - 38,637,869 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02338,778,573 - 38,881,960 (+)NCBIUU_Cfam_GSD_1.0
Pls1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560277,466,080 - 77,583,189 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365404,205,844 - 4,323,120 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365404,205,871 - 4,323,121 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1383,308,007 - 83,434,128 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11383,307,692 - 83,434,133 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PLS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11547,919,807 - 48,031,158 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1547,919,823 - 48,003,805 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604120,854,232 - 20,965,494 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pls1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473019,163,783 - 19,302,222 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473019,164,360 - 19,302,369 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000062089   ⟹   ENSPPAP00000039180
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3147,289,205 - 147,338,600 (+)Ensembl
RefSeq Acc Id: XM_003826515   ⟹   XP_003826563
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22140,505,061 - 140,623,025 (+)NCBI
NHGRI_mPanPan13140,512,368 - 140,627,757 (+)NCBI
Mhudiblu_PPA_v03139,629,827 - 139,747,080 (+)NCBI
PanPan1.13147,221,909 - 147,338,600 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034957552   ⟹   XP_034813443
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22140,505,059 - 140,623,025 (+)NCBI
NHGRI_mPanPan13140,512,368 - 140,627,757 (+)NCBI
Mhudiblu_PPA_v03139,629,826 - 139,745,468 (+)NCBI
RefSeq Acc Id: XM_034957553   ⟹   XP_034813444
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22140,505,057 - 140,617,020 (+)NCBI
NHGRI_mPanPan13140,512,368 - 140,621,034 (+)NCBI
Mhudiblu_PPA_v03139,629,825 - 139,738,745 (+)NCBI
RefSeq Acc Id: XM_055110580   ⟹   XP_054966555
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22140,505,058 - 140,623,025 (+)NCBI
NHGRI_mPanPan13140,512,373 - 140,627,757 (+)NCBI
RefSeq Acc Id: XM_055110581   ⟹   XP_054966556
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22140,490,169 - 140,623,025 (+)NCBI
NHGRI_mPanPan13140,494,901 - 140,627,757 (+)NCBI
RefSeq Acc Id: XM_055110582   ⟹   XP_054966557
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22140,505,060 - 140,623,025 (+)NCBI
NHGRI_mPanPan13140,512,373 - 140,627,757 (+)NCBI
RefSeq Acc Id: XM_055110584   ⟹   XP_054966559
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22140,490,165 - 140,623,025 (+)NCBI
NHGRI_mPanPan13140,494,897 - 140,627,757 (+)NCBI
RefSeq Acc Id: XM_055110586   ⟹   XP_054966561
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22140,567,839 - 140,623,025 (+)NCBI
NHGRI_mPanPan13140,572,571 - 140,627,757 (+)NCBI
RefSeq Acc Id: XM_055110587   ⟹   XP_054966562
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22140,530,263 - 140,623,025 (+)NCBI
NHGRI_mPanPan13140,535,067 - 140,627,757 (+)NCBI
RefSeq Acc Id: XP_003826563   ⟸   XM_003826515
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CB66 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034813444   ⟸   XM_034957553
- Peptide Label: isoform X3
RefSeq Acc Id: XP_034813443   ⟸   XM_034957552
- Peptide Label: isoform X1
RefSeq Acc Id: ENSPPAP00000039180   ⟸   ENSPPAT00000062089
RefSeq Acc Id: XP_054966559   ⟸   XM_055110584
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CB66 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054966556   ⟸   XM_055110581
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CB66 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054966555   ⟸   XM_055110580
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054966557   ⟸   XM_055110582
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CB66 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054966562   ⟸   XM_055110587
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CB66 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054966561   ⟸   XM_055110586
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CB66 (UniProtKB/TrEMBL)
Protein Domains
Calponin-homology (CH)   EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042289 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000062089.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro Actinin_actin-bd_CS UniProtKB/TrEMBL
  CH-domain UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  Fimbrin/Plastin UniProtKB/TrEMBL
KEGG Report pps:100974055 UniProtKB/TrEMBL
NCBI Gene PLS1 ENTREZGENE
PANTHER PTHR19961 UniProtKB/TrEMBL
  PTHR19961:SF27 UniProtKB/TrEMBL
Pfam EF-hand_7 UniProtKB/TrEMBL
  PF00307 UniProtKB/TrEMBL
PROSITE ACTININ_1 UniProtKB/TrEMBL
  ACTININ_2 UniProtKB/TrEMBL
  EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  PS50021 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
  SM00033 UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
  SSF47576 UniProtKB/TrEMBL
UniProt A0A2R9CB66 ENTREZGENE, UniProtKB/TrEMBL