Lrrc57 (leucine rich repeat containing 57) - Rat Genome Database

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Gene: Lrrc57 (leucine rich repeat containing 57) Rattus norvegicus
Analyze
Symbol: Lrrc57
Name: leucine rich repeat containing 57
RGD ID: 1307128
Description: Predicted to be located in membrane. Orthologous to human LRRC57 (leucine rich repeat containing 57); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: leucine-rich repeat-containing protein 57; leucine-rich repeat-containing protein 57-like; LOC100910478; LOC311346; MGC109337; RGD1307128; similar to RIKEN cDNA 2810002D13 gene
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83127,998,535 - 128,007,004 (-)NCBIGRCr8
mRatBN7.23107,544,786 - 107,553,256 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3107,547,405 - 107,553,256 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3111,222,226 - 111,228,070 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03119,817,799 - 119,823,643 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03117,478,192 - 117,484,036 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03112,365,936 - 112,371,787 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3112,365,938 - 112,385,528 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl3112,370,057 - 112,371,664 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03118,912,832 - 118,918,683 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43107,365,961 - 107,371,816 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13107,262,390 - 107,268,061 (-)NCBI
Celera3106,454,979 - 106,460,831 (-)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:19056867   PMID:21873635   PMID:22871113   PMID:23376485   PMID:23533145  


Genomics

Comparative Map Data
Lrrc57
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83127,998,535 - 128,007,004 (-)NCBIGRCr8
mRatBN7.23107,544,786 - 107,553,256 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3107,547,405 - 107,553,256 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3111,222,226 - 111,228,070 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03119,817,799 - 119,823,643 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03117,478,192 - 117,484,036 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03112,365,936 - 112,371,787 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3112,365,938 - 112,385,528 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl3112,370,057 - 112,371,664 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03118,912,832 - 118,918,683 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43107,365,961 - 107,371,816 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13107,262,390 - 107,268,061 (-)NCBI
Celera3106,454,979 - 106,460,831 (-)NCBICelera
Cytogenetic Map3q35NCBI
LRRC57
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381542,528,327 - 42,548,793 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1542,537,820 - 42,548,802 (-)EnsemblGRCh38hg38GRCh38
GRCh371542,830,027 - 42,840,991 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361540,622,014 - 40,628,292 (-)NCBINCBI36Build 36hg18NCBI36
Celera1519,602,426 - 19,608,708 (-)NCBICelera
Cytogenetic Map15q15.2NCBI
HuRef1519,682,473 - 19,688,755 (-)NCBIHuRef
CHM1_11542,953,162 - 42,959,444 (-)NCBICHM1_1
T2T-CHM13v2.01540,334,371 - 40,354,843 (-)NCBIT2T-CHM13v2.0
Lrrc57
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392120,434,719 - 120,439,989 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2120,434,719 - 120,440,001 (-)EnsemblGRCm39 Ensembl
GRCm382120,604,238 - 120,609,508 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2120,604,238 - 120,609,520 (-)EnsemblGRCm38mm10GRCm38
MGSCv372120,429,974 - 120,435,244 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362120,295,679 - 120,300,715 (-)NCBIMGSCv36mm8
Celera2121,757,029 - 121,762,300 (-)NCBICelera
Cytogenetic Map2E5NCBI
cM Map260.37NCBI
Lrrc57
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554169,230,362 - 9,237,799 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554169,230,362 - 9,237,799 (-)NCBIChiLan1.0ChiLan1.0
LRRC57
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21631,788,619 - 31,799,619 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11535,945,583 - 35,956,606 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01521,499,139 - 21,510,154 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11539,659,381 - 39,666,068 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1539,659,387 - 39,666,068 (-)Ensemblpanpan1.1panPan2
LRRC57
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1309,497,328 - 9,502,235 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha309,554,594 - 9,559,683 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0309,632,152 - 9,637,242 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl309,632,159 - 9,637,170 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1309,551,416 - 9,556,506 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0309,657,980 - 9,663,060 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0309,790,695 - 9,795,782 (-)NCBIUU_Cfam_GSD_1.0
Lrrc57
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864087,974,785 - 87,978,759 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364715,820,579 - 5,827,084 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364715,822,165 - 5,826,894 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRRC57
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1128,839,204 - 128,847,431 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11128,839,137 - 128,845,749 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21143,731,688 - 143,738,556 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LRRC57
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12640,427,588 - 40,434,108 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2640,427,887 - 40,432,553 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048100,578,130 - 100,584,784 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lrrc57
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248049,648,956 - 9,656,754 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248049,648,956 - 9,656,464 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lrrc57
25 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:383
Count of miRNA genes:227
Interacting mature miRNAs:258
Transcripts:ENSRNOT00000012636, ENSRNOT00000049756
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1582216Bw65Body weight QTL 656.3body mass (VT:0001259)body weight (CMO:0000012)3102200529115665732Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)396127817115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)384091273129091273Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)380800231114297550Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat

Markers in Region
BE101835  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23107,551,388 - 107,551,557 (+)MAPPERmRatBN7.2
Rnor_6.03112,383,844 - 112,384,012NCBIRnor6.0
Rnor_6.03112,369,920 - 112,370,088NCBIRnor6.0
Rnor_5.03118,930,740 - 118,930,908UniSTSRnor5.0
Rnor_5.03118,916,816 - 118,916,984UniSTSRnor5.0
RGSC_v3.43107,369,949 - 107,370,117UniSTSRGSC3.4
Celera3106,458,964 - 106,459,132UniSTS
RH 3.4 Map3941.6UniSTS
Cytogenetic Map3q35UniSTS
Cytogenetic Map19q12UniSTS
RH134600  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23107,547,606 - 107,547,786 (+)MAPPERmRatBN7.2
Rnor_6.03112,366,140 - 112,366,319NCBIRnor6.0
Rnor_5.03118,913,036 - 118,913,215UniSTSRnor5.0
RGSC_v3.43107,366,165 - 107,366,344UniSTSRGSC3.4
Celera3106,455,183 - 106,455,362UniSTS
RH 3.4 Map3940.9UniSTS
Cytogenetic Map3q35UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
18 22 70 202 161 160 98 50 98 12 373 165 163 76 108 62

Sequence


Ensembl Acc Id: ENSRNOT00000012636   ⟹   ENSRNOP00000012636
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3112,370,057 - 112,371,664 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000049756   ⟹   ENSRNOP00000050922
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3107,547,405 - 107,553,256 (-)Ensembl
Rnor_6.0 Ensembl3112,365,938 - 112,385,528 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000079606   ⟹   ENSRNOP00000075733
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3112,370,057 - 112,371,664 (-)Ensembl
RefSeq Acc Id: NM_001012354   ⟹   NP_001012354
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83128,001,152 - 128,007,004 (-)NCBI
mRatBN7.23107,547,403 - 107,553,256 (-)NCBI
Rnor_6.03112,365,936 - 112,371,787 (-)NCBI
Rnor_5.03118,912,832 - 118,918,683 (-)NCBI
RGSC_v3.43107,365,961 - 107,371,816 (-)RGD
Celera3106,454,979 - 106,460,831 (-)RGD
Sequence:
RefSeq Acc Id: XM_006234777   ⟹   XP_006234839
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83127,998,535 - 128,006,968 (-)NCBI
mRatBN7.23107,544,786 - 107,553,210 (-)NCBI
Rnor_6.03112,365,936 - 112,371,688 (-)NCBI
Rnor_5.03118,912,832 - 118,918,683 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006234778   ⟹   XP_006234840
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83127,998,535 - 128,006,907 (-)NCBI
mRatBN7.23107,544,786 - 107,553,157 (-)NCBI
Rnor_6.03112,365,936 - 112,371,631 (-)NCBI
Rnor_5.03118,912,832 - 118,918,683 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006234779   ⟹   XP_006234841
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83127,998,535 - 128,006,832 (-)NCBI
mRatBN7.23107,544,786 - 107,553,080 (-)NCBI
Rnor_6.03112,365,936 - 112,371,561 (-)NCBI
Rnor_5.03118,912,832 - 118,918,683 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006234780   ⟹   XP_006234842
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83127,998,535 - 128,006,881 (-)NCBI
mRatBN7.23107,544,786 - 107,553,136 (-)NCBI
Rnor_6.03112,365,936 - 112,371,680 (-)NCBI
Rnor_5.03118,912,832 - 118,918,683 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001012354   ⟸   NM_001012354
- UniProtKB: Q5FVI3 (UniProtKB/Swiss-Prot),   A6HPK4 (UniProtKB/TrEMBL),   A6HPK3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234839   ⟸   XM_006234777
- Peptide Label: isoform X1
- UniProtKB: A6HPK3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234842   ⟸   XM_006234780
- Peptide Label: isoform X3
- UniProtKB: A6HPK3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234840   ⟸   XM_006234778
- Peptide Label: isoform X2
- UniProtKB: Q5FVI3 (UniProtKB/Swiss-Prot),   A6HPK4 (UniProtKB/TrEMBL),   A6HPK3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234841   ⟸   XM_006234779
- Peptide Label: isoform X2
- UniProtKB: Q5FVI3 (UniProtKB/Swiss-Prot),   A6HPK4 (UniProtKB/TrEMBL),   A6HPK3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075733   ⟸   ENSRNOT00000079606
Ensembl Acc Id: ENSRNOP00000012636   ⟸   ENSRNOT00000012636
Ensembl Acc Id: ENSRNOP00000050922   ⟸   ENSRNOT00000049756

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5FVI3-F1-model_v2 AlphaFold Q5FVI3 1-239 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307128 AgrOrtholog
BioCyc Gene G2FUF-48160 BioCyc
Ensembl Genes ENSRNOG00000009143 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000048310 Ensembl
  ENSRNOG00055002224 UniProtKB/Swiss-Prot
  ENSRNOG00060028465 UniProtKB/Swiss-Prot
  ENSRNOG00065025679 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000049756.6 UniProtKB/Swiss-Prot
  ENSRNOT00055003534 UniProtKB/Swiss-Prot
  ENSRNOT00060049487 UniProtKB/Swiss-Prot
  ENSRNOT00065044251 UniProtKB/Swiss-Prot
Gene3D-CATH 3.80.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7314989 IMAGE-MGC_LOAD
InterPro Leu-rich_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_domain-containing UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:311346 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:109337 IMAGE-MGC_LOAD
NCBI Gene 311346 ENTREZGENE
PANTHER LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47-LIKE PROTEIN UniProtKB/TrEMBL
  PTHR48051 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZGC:77287 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LRR_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lrrc57 PhenoGen
PRINTS LEURICHRPT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE LRR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009143 RatGTEx
  ENSRNOG00000048310 RatGTEx
  ENSRNOG00055002224 RatGTEx
  ENSRNOG00060028465 RatGTEx
  ENSRNOG00065025679 RatGTEx
SMART LRR_BAC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_TYP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6HPK3 ENTREZGENE, UniProtKB/TrEMBL
  A6HPK4 ENTREZGENE, UniProtKB/TrEMBL
  LRC57_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Lrrc57  leucine rich repeat containing 57  LOC100910478  leucine-rich repeat-containing protein 57-like  Data merged from RGD:6498299 737654 PROVISIONAL
2012-07-05 LOC100910478  leucine-rich repeat-containing protein 57-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-07 Lrrc57  leucine rich repeat containing 57  RGD1307128  similar to RIKEN cDNA 2810002D13 gene  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1307128  similar to RIKEN cDNA 2810002D13 gene  RGD1307128_predicted  similar to RIKEN cDNA 2810002D13 gene (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1307128_predicted  similar to RIKEN cDNA 2810002D13 gene (predicted)  LOC311346_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC311346_predicted  similar to RIKEN cDNA 2810002D13 gene (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL