Fignl1 (fidgetin-like 1) - Rat Genome Database

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Gene: Fignl1 (fidgetin-like 1) Rattus norvegicus
Analyze
Symbol: Fignl1
Name: fidgetin-like 1
RGD ID: 1307112
Description: Predicted to enable ATP hydrolysis activity; magnesium ion binding activity; and microtubule severing ATPase activity. Predicted to be involved in several processes, including microtubule severing; osteoblast proliferation; and regulation of double-strand break repair via homologous recombination. Predicted to act upstream of or within negative regulation of intrinsic apoptotic signaling pathway. Predicted to be located in nuclear chromosome and perinuclear region of cytoplasm. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in nicotine dependence. Orthologous to human FIGNL1 (fidgetin like 1); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: fidgetin-like protein 1; LOC289777
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81490,573,090 - 90,595,342 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1490,581,771 - 90,592,316 (-)EnsemblGRCr8
mRatBN7.21486,368,670 - 86,381,728 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1486,368,675 - 86,377,455 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1490,774,815 - 90,783,162 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01492,019,146 - 92,027,493 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01488,486,779 - 88,495,126 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01491,895,902 - 91,904,474 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1491,895,909 - 91,904,433 (-)Ensemblrn6Rnor6.0
Rnor_5.01491,679,879 - 91,688,446 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41492,685,445 - 92,693,967 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1485,370,247 - 85,378,768 (-)NCBICelera
RGSC_v3.11492,704,589 - 92,713,112 (-)NCBI
Cytogenetic Map14q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dichloroethane  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-diaminotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
dibenz[a,h]anthracene  (ISO)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
dimethyl sulfoxide  (ISO)
dorsomorphin  (ISO)
Enterolactone  (ISO)
folic acid  (ISO)
furan  (EXP)
gentamycin  (EXP)
glyphosate  (EXP)
hydrogen peroxide  (ISO)
L-methionine  (ISO)
lidocaine  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methylmercury chloride  (ISO)
Muraglitazar  (EXP)
N-nitrosodiethylamine  (ISO)
niclosamide  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO,ISS)
DNA repair complex  (ISO)
nuclear chromosome  (ISO,ISS)
nucleus  (IBA,IEA,ISO,ISS)
perinuclear region of cytoplasm  (IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Intronic variants in the dopa decarboxylase (DDC) gene are associated with smoking behavior in European-Americans and African-Americans. Yu Y, etal., Hum Mol Genet. 2006 Jul 15;15(14):2192-9. doi: 10.1093/hmg/ddl144. Epub 2006 Jun 1.
Additional References at PubMed
PMID:16288221   PMID:17352653   PMID:19056867   PMID:20886204   PMID:22110678   PMID:23533145   PMID:23754376  


Genomics

Comparative Map Data
Fignl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81490,573,090 - 90,595,342 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1490,581,771 - 90,592,316 (-)EnsemblGRCr8
mRatBN7.21486,368,670 - 86,381,728 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1486,368,675 - 86,377,455 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1490,774,815 - 90,783,162 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01492,019,146 - 92,027,493 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01488,486,779 - 88,495,126 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01491,895,902 - 91,904,474 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1491,895,909 - 91,904,433 (-)Ensemblrn6Rnor6.0
Rnor_5.01491,679,879 - 91,688,446 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41492,685,445 - 92,693,967 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1485,370,247 - 85,378,768 (-)NCBICelera
RGSC_v3.11492,704,589 - 92,713,112 (-)NCBI
Cytogenetic Map14q21NCBI
FIGNL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38750,444,133 - 50,450,350 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl750,444,128 - 50,450,406 (-)Ensemblhg38GRCh38
GRCh37750,511,831 - 50,518,048 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36750,479,325 - 50,485,582 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34750,286,040 - 50,292,257NCBI
Celera750,576,751 - 50,583,008 (-)NCBICelera
Cytogenetic Map7p12.2NCBI
HuRef750,361,796 - 50,368,053 (-)NCBIHuRef
CHM1_1750,514,123 - 50,520,380 (-)NCBICHM1_1
T2T-CHM13v2.0750,605,348 - 50,611,565 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2750,517,901 - 50,524,158 (-)NCBI
Fignl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391111,737,429 - 11,758,962 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1111,737,431 - 11,758,962 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381111,800,288 - 11,808,983 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1111,787,431 - 11,808,962 (-)Ensemblmm10GRCm38
MGSCv371111,700,291 - 11,708,965 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361111,700,291 - 11,708,935 (-)NCBIMGSCv36mm8
Celera1112,259,567 - 12,268,241 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map117.08NCBI
Fignl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554563,588,714 - 3,594,559 (+)Ensembl
ChiLan1.0NW_0049554563,588,190 - 3,594,559 (+)NCBIChiLan1.0ChiLan1.0
FIGNL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2655,323,098 - 55,329,366 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17103,647,823 - 103,654,089 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0751,080,052 - 51,093,694 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1751,330,922 - 51,337,201 (-)NCBIPanPan1.1PanPan1.1panPan2
FIGNL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1181,788,063 - 1,792,900 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl181,788,801 - 1,790,831 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha181,779,396 - 1,786,125 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0181,846,815 - 1,853,537 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl181,846,410 - 1,852,892 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1181,819,812 - 1,826,451 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0181,816,264 - 1,822,220 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0181,953,038 - 1,959,746 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fignl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118105,107,576 - 105,111,027 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366861,413,218 - 1,415,248 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366861,412,544 - 1,415,939 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FIGNL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9136,484,216 - 136,488,250 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.19136,484,217 - 136,488,262 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29150,064,983 - 150,068,988 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FIGNL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1218,351,116 - 8,357,841 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl218,354,641 - 8,356,665 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606213,923,269 - 13,930,007 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fignl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247403,739,765 - 3,741,858 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247403,737,482 - 3,748,851 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Fignl1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11180,721,458 - 80,724,267 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fignl1
144 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:66
Count of miRNA genes:54
Interacting mature miRNAs:61
Transcripts:ENSRNOT00000005857
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1484164970100078267Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
4889951Bss92Bone structure and strength QTL 923.9tibia area (VT:1000281)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)1486271332100078267Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat

Markers in Region
RH142989  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21486,376,657 - 86,376,847 (+)MAPPERmRatBN7.2
Rnor_6.01491,903,892 - 91,904,081NCBIRnor6.0
Rnor_5.01491,687,867 - 91,688,056UniSTSRnor5.0
RGSC_v3.41492,693,426 - 92,693,615UniSTSRGSC3.4
Celera1485,378,227 - 85,378,416UniSTS
RH 3.4 Map14635.59UniSTS
Cytogenetic Map14q21UniSTS
RH143134  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21486,378,764 - 86,378,934 (+)MAPPERmRatBN7.2
Rnor_6.01491,905,999 - 91,906,168NCBIRnor6.0
Rnor_5.01491,689,974 - 91,690,143UniSTSRnor5.0
RGSC_v3.41492,695,533 - 92,695,702UniSTSRGSC3.4
Celera1485,380,334 - 85,380,503UniSTS
RH 3.4 Map14636.59UniSTS
Cytogenetic Map14q21UniSTS
UniSTS:236520  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21486,370,105 - 86,370,263 (+)MAPPERmRatBN7.2
Rnor_6.01491,897,340 - 91,897,497NCBIRnor6.0
Rnor_5.01491,681,315 - 91,681,472UniSTSRnor5.0
RGSC_v3.41492,686,874 - 92,687,031UniSTSRGSC3.4
Celera1485,371,676 - 85,371,833UniSTS
Cytogenetic Map14q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 66 164 91 90 59 85 59 6 345 183 11 143 79 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000005857   ⟹   ENSRNOP00000005857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1490,582,325 - 90,590,759 (-)Ensembl
mRatBN7.2 Ensembl1486,368,675 - 86,377,199 (-)Ensembl
Rnor_6.0 Ensembl1491,895,909 - 91,904,433 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107994   ⟹   ENSRNOP00000078689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1490,581,771 - 90,590,954 (-)Ensembl
mRatBN7.2 Ensembl1486,368,677 - 86,377,455 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000134653   ⟹   ENSRNOP00000101365
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1490,581,772 - 90,592,316 (-)Ensembl
RefSeq Acc Id: NM_001011913   ⟹   NP_001011913
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,582,289 - 90,590,818 (-)NCBI
mRatBN7.21486,368,670 - 86,377,199 (-)NCBI
Rnor_6.01491,895,911 - 91,904,433 (-)NCBI
Rnor_5.01491,679,879 - 91,688,446 (-)NCBI
RGSC_v3.41492,685,445 - 92,693,967 (-)RGD
Celera1485,370,247 - 85,378,768 (-)RGD
Sequence:
RefSeq Acc Id: NM_001393808   ⟹   NP_001380737
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,582,289 - 90,590,818 (-)NCBI
mRatBN7.21486,368,670 - 86,377,199 (-)NCBI
RefSeq Acc Id: NM_001393809   ⟹   NP_001380738
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,582,289 - 90,590,818 (-)NCBI
mRatBN7.21486,368,670 - 86,377,199 (-)NCBI
RefSeq Acc Id: XM_006251477   ⟹   XP_006251539
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,582,293 - 90,595,342 (-)NCBI
mRatBN7.21486,368,671 - 86,381,728 (-)NCBI
Rnor_6.01491,895,902 - 91,904,357 (-)NCBI
Rnor_5.01491,679,879 - 91,688,446 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063272953   ⟹   XP_063129023
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,582,293 - 90,584,895 (-)NCBI
RefSeq Acc Id: XM_063272954   ⟹   XP_063129024
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,573,090 - 90,584,895 (-)NCBI
RefSeq Acc Id: NP_001011913   ⟸   NM_001011913
- UniProtKB: Q6GX84 (UniProtKB/Swiss-Prot),   A6KJB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251539   ⟸   XM_006251477
- Peptide Label: isoform X1
- UniProtKB: Q6GX84 (UniProtKB/Swiss-Prot),   A6KJB2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000005857   ⟸   ENSRNOT00000005857
Ensembl Acc Id: ENSRNOP00000078689   ⟸   ENSRNOT00000107994
RefSeq Acc Id: NP_001380738   ⟸   NM_001393809
- UniProtKB: Q6GX84 (UniProtKB/Swiss-Prot),   A6KJB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001380737   ⟸   NM_001393808
- UniProtKB: Q6GX84 (UniProtKB/Swiss-Prot),   A6KJB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129024   ⟸   XM_063272954
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063129023   ⟸   XM_063272953
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000101365   ⟸   ENSRNOT00000134653
Protein Domains
AAA+ ATPase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6GX84-F1-model_v2 AlphaFold Q6GX84 1-677 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699495
Promoter ID:EPDNEW_R10017
Type:single initiation site
Name:Fignl1_1
Description:fidgetin-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01491,904,422 - 91,904,482EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307112 AgrOrtholog
BioCyc Gene G2FUF-14990 BioCyc
Ensembl Genes ENSRNOG00000004440 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000005857 ENTREZGENE
  ENSRNOT00000005857.5 UniProtKB/Swiss-Prot
  ENSRNOT00000107994 ENTREZGENE
  ENSRNOT00000107994.1 UniProtKB/Swiss-Prot
  ENSRNOT00000134653 ENTREZGENE
Gene3D-CATH 1.10.8.60 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
InterPro AAA+_ATPase UniProtKB/Swiss-Prot
  AAA_lid_3 UniProtKB/Swiss-Prot
  ATPase_AAA_core UniProtKB/Swiss-Prot
  ATPase_AAA_CS UniProtKB/Swiss-Prot
  FIGNL1_ATPase UniProtKB/Swiss-Prot
  MT-severing_AAA_ATPase UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  Vps4_C UniProtKB/Swiss-Prot
KEGG Report rno:289777 UniProtKB/Swiss-Prot
NCBI Gene 289777 ENTREZGENE
PANTHER AAA DOMAIN-CONTAINING UniProtKB/Swiss-Prot
  DYNEIN REGULATORY COMPLEX PROTEIN 11-RELATED UniProtKB/Swiss-Prot
Pfam AAA UniProtKB/Swiss-Prot
  AAA_lid_3 UniProtKB/Swiss-Prot
  Vps4_C UniProtKB/Swiss-Prot
PhenoGen Fignl1 PhenoGen
PROSITE AAA UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000004440 RatGTEx
SMART AAA UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A6KJB2 ENTREZGENE, UniProtKB/TrEMBL
  FIGL1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Fignl1  fidgetin-like 1  Fignl1_predicted  fidgetin-like 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Fignl1_predicted  fidgetin-like 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED