Fignl1 (fidgetin-like 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Fignl1 (fidgetin-like 1) Rattus norvegicus
Analyze
Symbol: Fignl1
Name: fidgetin-like 1
RGD ID: 1307112
Description: Predicted to enable hydrolase activity; magnesium ion binding activity; and microtubule severing ATPase activity. Predicted to be involved in several processes, including cellular response to ionizing radiation; osteoblast proliferation; and regulation of double-strand break repair via homologous recombination. Predicted to act upstream of or within negative regulation of intrinsic apoptotic signaling pathway. Predicted to be located in nuclear chromosome and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in nicotine dependence. Orthologous to human FIGNL1 (fidgetin like 1); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: fidgetin-like protein 1; LOC289777
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81490,573,090 - 90,595,342 (-)NCBIGRCr8
mRatBN7.21486,368,670 - 86,381,728 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1486,368,675 - 86,377,455 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1490,774,815 - 90,783,162 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01492,019,146 - 92,027,493 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01488,486,779 - 88,495,126 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01491,895,902 - 91,904,474 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1491,895,909 - 91,904,433 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01491,679,879 - 91,688,446 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41492,685,445 - 92,693,967 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11492,704,589 - 92,713,112 (-)NCBI
Celera1485,370,247 - 85,378,768 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-diaminotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-methylcholanthrene  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP)
calcitriol  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
dibenz[a,h]anthracene  (ISO)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
Enterolactone  (ISO)
folic acid  (ISO)
furan  (EXP)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
L-methionine  (ISO)
lidocaine  (EXP)
methylmercury chloride  (ISO)
Muraglitazar  (EXP)
N-nitrosodiethylamine  (ISO)
niclosamide  (ISO)
ozone  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO,ISS)
nuclear chromosome  (ISO,ISS)
nucleus  (ISO,ISS)
perinuclear region of cytoplasm  (ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Intronic variants in the dopa decarboxylase (DDC) gene are associated with smoking behavior in European-Americans and African-Americans. Yu Y, etal., Hum Mol Genet. 2006 Jul 15;15(14):2192-9. doi: 10.1093/hmg/ddl144. Epub 2006 Jun 1.
Additional References at PubMed
PMID:16288221   PMID:17352653   PMID:19056867   PMID:20886204   PMID:22110678   PMID:23533145   PMID:23754376  


Genomics

Comparative Map Data
Fignl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81490,573,090 - 90,595,342 (-)NCBIGRCr8
mRatBN7.21486,368,670 - 86,381,728 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1486,368,675 - 86,377,455 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1490,774,815 - 90,783,162 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01492,019,146 - 92,027,493 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01488,486,779 - 88,495,126 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01491,895,902 - 91,904,474 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1491,895,909 - 91,904,433 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01491,679,879 - 91,688,446 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41492,685,445 - 92,693,967 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11492,704,589 - 92,713,112 (-)NCBI
Celera1485,370,247 - 85,378,768 (-)NCBICelera
Cytogenetic Map14q21NCBI
FIGNL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38750,444,133 - 50,450,350 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl750,444,128 - 50,450,390 (-)EnsemblGRCh38hg38GRCh38
GRCh37750,511,831 - 50,518,048 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36750,479,325 - 50,485,582 (-)NCBINCBI36Build 36hg18NCBI36
Build 34750,286,040 - 50,292,257NCBI
Celera750,576,751 - 50,583,008 (-)NCBICelera
Cytogenetic Map7p12.2NCBI
HuRef750,361,796 - 50,368,053 (-)NCBIHuRef
CHM1_1750,514,123 - 50,520,380 (-)NCBICHM1_1
T2T-CHM13v2.0750,605,348 - 50,611,565 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2750,517,901 - 50,524,158 (-)NCBI
Fignl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391111,737,429 - 11,758,962 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1111,737,431 - 11,758,962 (-)EnsemblGRCm39 Ensembl
GRCm381111,800,288 - 11,808,983 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1111,787,431 - 11,808,962 (-)EnsemblGRCm38mm10GRCm38
MGSCv371111,700,291 - 11,708,965 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361111,700,291 - 11,708,935 (-)NCBIMGSCv36mm8
Celera1112,259,567 - 12,268,241 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map117.08NCBI
Fignl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554563,588,714 - 3,594,559 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554563,588,190 - 3,594,559 (+)NCBIChiLan1.0ChiLan1.0
FIGNL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2655,323,098 - 55,329,366 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17103,647,823 - 103,654,089 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0751,080,052 - 51,093,694 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1751,330,922 - 51,337,201 (-)NCBIpanpan1.1PanPan1.1panPan2
FIGNL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1181,788,063 - 1,792,900 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl181,788,801 - 1,790,831 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha181,779,396 - 1,786,125 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0181,846,815 - 1,853,537 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl181,846,410 - 1,852,892 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1181,819,812 - 1,826,451 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0181,816,264 - 1,822,220 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0181,953,038 - 1,959,746 (-)NCBIUU_Cfam_GSD_1.0
Fignl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118105,107,576 - 105,111,027 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366861,413,218 - 1,415,248 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366861,412,544 - 1,415,939 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FIGNL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9136,484,216 - 136,488,250 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19136,484,217 - 136,488,262 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29150,064,983 - 150,068,988 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FIGNL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1218,351,116 - 8,357,841 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl218,354,641 - 8,356,665 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606213,923,269 - 13,930,007 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fignl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247403,739,765 - 3,741,858 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247403,737,482 - 3,748,851 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fignl1
36 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:66
Count of miRNA genes:54
Interacting mature miRNAs:61
Transcripts:ENSRNOT00000005857
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
4889951Bss92Bone structure and strength QTL 923.9tibia area (VT:1000281)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)148205747195876975Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1455624247100624247Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)145002321195023211Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147341532392554092Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532395876975Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147341532392554092Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)147995092195876975Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat

Markers in Region
RH142989  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21486,376,657 - 86,376,847 (+)MAPPERmRatBN7.2
Rnor_6.01491,903,892 - 91,904,081NCBIRnor6.0
Rnor_5.01491,687,867 - 91,688,056UniSTSRnor5.0
RGSC_v3.41492,693,426 - 92,693,615UniSTSRGSC3.4
Celera1485,378,227 - 85,378,416UniSTS
RH 3.4 Map14635.59UniSTS
Cytogenetic Map14q21UniSTS
RH143134  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21486,378,764 - 86,378,934 (+)MAPPERmRatBN7.2
Rnor_6.01491,905,999 - 91,906,168NCBIRnor6.0
Rnor_5.01491,689,974 - 91,690,143UniSTSRnor5.0
RGSC_v3.41492,695,533 - 92,695,702UniSTSRGSC3.4
Celera1485,380,334 - 85,380,503UniSTS
RH 3.4 Map14636.59UniSTS
Cytogenetic Map14q21UniSTS
UniSTS:236520  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21486,370,105 - 86,370,263 (+)MAPPERmRatBN7.2
Rnor_6.01491,897,340 - 91,897,497NCBIRnor6.0
Rnor_5.01491,681,315 - 91,681,472UniSTSRnor5.0
RGSC_v3.41492,686,874 - 92,687,031UniSTSRGSC3.4
Celera1485,371,676 - 85,371,833UniSTS
Cytogenetic Map14q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 26 19 18 4 18 10 12 26
Low 3 13 30 15 15 15 2 2 60 20 15 11 2
Below cutoff 4 8 8 8 6 8 4 3 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000005857   ⟹   ENSRNOP00000005857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1486,368,675 - 86,377,199 (-)Ensembl
Rnor_6.0 Ensembl1491,895,909 - 91,904,433 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107994   ⟹   ENSRNOP00000078689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1486,368,677 - 86,377,455 (-)Ensembl
RefSeq Acc Id: NM_001011913   ⟹   NP_001011913
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,582,289 - 90,590,818 (-)NCBI
mRatBN7.21486,368,670 - 86,377,199 (-)NCBI
Rnor_6.01491,895,911 - 91,904,433 (-)NCBI
Rnor_5.01491,679,879 - 91,688,446 (-)NCBI
RGSC_v3.41492,685,445 - 92,693,967 (-)RGD
Celera1485,370,247 - 85,378,768 (-)RGD
Sequence:
RefSeq Acc Id: NM_001393808   ⟹   NP_001380737
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,582,289 - 90,590,818 (-)NCBI
mRatBN7.21486,368,670 - 86,377,199 (-)NCBI
RefSeq Acc Id: NM_001393809   ⟹   NP_001380738
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,582,289 - 90,590,818 (-)NCBI
mRatBN7.21486,368,670 - 86,377,199 (-)NCBI
RefSeq Acc Id: XM_006251477   ⟹   XP_006251539
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,582,293 - 90,595,342 (-)NCBI
mRatBN7.21486,368,671 - 86,381,728 (-)NCBI
Rnor_6.01491,895,902 - 91,904,357 (-)NCBI
Rnor_5.01491,679,879 - 91,688,446 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063272953   ⟹   XP_063129023
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,582,293 - 90,584,895 (-)NCBI
RefSeq Acc Id: XM_063272954   ⟹   XP_063129024
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,573,090 - 90,584,895 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001011913   ⟸   NM_001011913
- UniProtKB: Q6GX84 (UniProtKB/Swiss-Prot),   A6KJB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251539   ⟸   XM_006251477
- Peptide Label: isoform X1
- UniProtKB: Q6GX84 (UniProtKB/Swiss-Prot),   A6KJB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000005857   ⟸   ENSRNOT00000005857
RefSeq Acc Id: ENSRNOP00000078689   ⟸   ENSRNOT00000107994
RefSeq Acc Id: NP_001380738   ⟸   NM_001393809
- UniProtKB: Q6GX84 (UniProtKB/Swiss-Prot),   A6KJB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001380737   ⟸   NM_001393808
- UniProtKB: Q6GX84 (UniProtKB/Swiss-Prot),   A6KJB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129024   ⟸   XM_063272954
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063129023   ⟸   XM_063272953
- Peptide Label: isoform X2
Protein Domains
AAA+ ATPase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6GX84-F1-model_v2 AlphaFold Q6GX84 1-677 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699495
Promoter ID:EPDNEW_R10017
Type:single initiation site
Name:Fignl1_1
Description:fidgetin-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01491,904,422 - 91,904,482EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307112 AgrOrtholog
BioCyc Gene G2FUF-14990 BioCyc
Ensembl Genes ENSRNOG00000004440 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000005857 ENTREZGENE
  ENSRNOT00000005857.5 UniProtKB/Swiss-Prot
  ENSRNOT00000107994.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.8.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATPase_AAA_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FIGNL1_ATPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Spast_Vps4_C UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
KEGG Report rno:289777 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 289777 ENTREZGENE
PANTHER AAA DOMAIN-CONTAINING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DYNEIN REGULATORY COMPLEX PROTEIN 11-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Vps4_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fignl1 PhenoGen
PROSITE AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004440 RatGTEx
SMART AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP P-loop containing nucleoside triphosphate hydrolases UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A6KJB2 ENTREZGENE, UniProtKB/TrEMBL
  FIGL1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Fignl1  fidgetin-like 1  Fignl1_predicted  fidgetin-like 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Fignl1_predicted  fidgetin-like 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED