Fignl1 (fidgetin like 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Fignl1 (fidgetin like 1) Ictidomys tridecemlineatus
Analyze
Symbol: Fignl1
Name: fidgetin like 1
RGD ID: 12576266
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); microtubule severing ATPase activity (inferred); INVOLVED IN negative regulation of intrinsic apoptotic signaling pathway (ortholog); ASSOCIATED WITH genetic disease (ortholog); Kidney Neoplasms (ortholog); nicotine dependence (ortholog); FOUND IN cytoplasm (inferred); nuclear chromosome (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fidgetin-like protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118105,107,576 - 105,111,027 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366861,413,218 - 1,415,248 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366861,412,544 - 1,415,939 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Fignl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118105,107,576 - 105,111,027 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366861,413,218 - 1,415,248 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366861,412,544 - 1,415,939 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FIGNL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38750,444,133 - 50,450,350 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl750,444,128 - 50,450,390 (-)EnsemblGRCh38hg38GRCh38
GRCh37750,511,831 - 50,518,048 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36750,479,325 - 50,485,582 (-)NCBINCBI36Build 36hg18NCBI36
Build 34750,286,040 - 50,292,257NCBI
Celera750,576,751 - 50,583,008 (-)NCBICelera
Cytogenetic Map7p12.2NCBI
HuRef750,361,796 - 50,368,053 (-)NCBIHuRef
CHM1_1750,514,123 - 50,520,380 (-)NCBICHM1_1
T2T-CHM13v2.0750,605,348 - 50,611,565 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2750,517,901 - 50,524,158 (-)NCBI
Fignl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391111,737,429 - 11,758,962 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1111,737,431 - 11,758,962 (-)EnsemblGRCm39 Ensembl
GRCm381111,800,288 - 11,808,983 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1111,787,431 - 11,808,962 (-)EnsemblGRCm38mm10GRCm38
MGSCv371111,700,291 - 11,708,965 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361111,700,291 - 11,708,935 (-)NCBIMGSCv36mm8
Celera1112,259,567 - 12,268,241 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map117.08NCBI
Fignl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81490,573,090 - 90,595,342 (-)NCBIGRCr8
mRatBN7.21486,368,670 - 86,381,728 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1486,368,675 - 86,377,455 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1490,774,815 - 90,783,162 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01492,019,146 - 92,027,493 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01488,486,779 - 88,495,126 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01491,895,902 - 91,904,474 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1491,895,909 - 91,904,433 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01491,679,879 - 91,688,446 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41492,685,445 - 92,693,967 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11492,704,589 - 92,713,112 (-)NCBI
Celera1485,370,247 - 85,378,768 (-)NCBICelera
Cytogenetic Map14q21NCBI
Fignl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554563,588,714 - 3,594,559 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554563,588,190 - 3,594,559 (+)NCBIChiLan1.0ChiLan1.0
FIGNL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2655,323,098 - 55,329,366 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17103,647,823 - 103,654,089 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0751,080,052 - 51,093,694 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1751,330,922 - 51,337,201 (-)NCBIpanpan1.1PanPan1.1panPan2
FIGNL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1181,788,063 - 1,792,900 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl181,788,801 - 1,790,831 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha181,779,396 - 1,786,125 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0181,846,815 - 1,853,537 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl181,846,410 - 1,852,892 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1181,819,812 - 1,826,451 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0181,816,264 - 1,822,220 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0181,953,038 - 1,959,746 (-)NCBIUU_Cfam_GSD_1.0
FIGNL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9136,484,216 - 136,488,250 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19136,484,217 - 136,488,262 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29150,064,983 - 150,068,988 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FIGNL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1218,351,116 - 8,357,841 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl218,354,641 - 8,356,665 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606213,923,269 - 13,930,007 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fignl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247403,739,765 - 3,741,858 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247403,737,482 - 3,748,851 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005337545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000003582   ⟹   ENSSTOP00000003208
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366861,413,218 - 1,415,248 (+)Ensembl
RefSeq Acc Id: XM_005337545   ⟹   XP_005337602
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118105,107,576 - 105,111,027 (-)NCBI
SpeTri2.0NW_0049366861,412,544 - 1,415,939 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005337602 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000003208.3
GenBank Protein KAG3278282 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005337602   ⟸   XM_005337545
- UniProtKB: I3M2J3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000003208   ⟸   ENSSTOT00000003582
Protein Domains
AAA+ ATPase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000003589 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000003582.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.60 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  AAA_lid_3 UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  ATPase_AAA_CS UniProtKB/TrEMBL
  FIGNL1_ATPase UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Vps4_C UniProtKB/TrEMBL
NCBI Gene Fignl1 ENTREZGENE
PANTHER AAA DOMAIN-CONTAINING UniProtKB/TrEMBL
  DYNEIN REGULATORY COMPLEX PROTEIN 11-RELATED UniProtKB/TrEMBL
Pfam AAA UniProtKB/TrEMBL
  AAA_lid_3 UniProtKB/TrEMBL
  Vps4_C UniProtKB/TrEMBL
PROSITE AAA UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt I3M2J3 ENTREZGENE, UniProtKB/TrEMBL