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Gene: Piwil1 (piwi-like RNA-mediated gene silencing 1) Rattus norvegicus

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Symbol:

Piwil1

Name:

piwi-like RNA-mediated gene silencing 1

RGD ID:

1306980

Description:

Predicted to enable several functions, including RNA binding activity; mRNA cap binding complex binding activity; and protein kinase binding activity. Predicted to be involved in regulatory ncRNA-mediated gene silencing and sperm DNA condensation. Predicted to be located in chromatoid body and dense body. Predicted to be active in P granule and nucleus. Orthologous to human PIWIL1 (piwi like RNA-mediated gene silencing 1); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC363912; piwi like homolog 1; piwi like homolog 1 (Drosophila); piwi-like 1; piwi-like 1 (Drosophila); piwi-like protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PIWIL1 (piwi like RNA-mediated gene silencing 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Piwil1 (piwi-like RNA-mediated gene silencing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Piwil1 (piwi like RNA-mediated gene silencing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PIWIL1 (piwi like RNA-mediated gene silencing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PIWIL1 (piwi like RNA-mediated gene silencing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Piwil1 (piwi like RNA-mediated gene silencing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PIWIL1 (piwi like RNA-mediated gene silencing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PIWIL1 (piwi like RNA-mediated gene silencing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Piwil1 (piwi like RNA-mediated gene silencing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Piwil1 (piwi like RNA-mediated gene silencing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PIWIL3 (piwi like RNA-mediated gene silencing 3)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	PIWIL1 (piwi like RNA-mediated gene silencing 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Piwil1 (piwi-like RNA-mediated gene silencing 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	piwil1 (piwi-like RNA-mediated gene silencing 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	AGO3	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	AGO3	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|SonicParanoid)
Caenorhabditis elegans (roundworm):	prg-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	prg-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	aub	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	aub	Alliance	DIOPT (Hieranoid\|OMA\|PANTHER)
Drosophila melanogaster (fruit fly):	piwi	Alliance	DIOPT (Hieranoid\|OMA\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	piwi	Alliance	DIOPT (Hieranoid\|OMA\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	piwil3	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	piwil3	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	piwil1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	piwil1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	33,585,747 - 33,606,715 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	33,585,747 - 33,606,591 (-)	Ensembl				GRCr8
mRatBN7.2	12	27,949,743 - 27,970,645 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	27,949,744 - 27,970,580 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	29,089,050 - 29,109,905 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	29,699,619 - 29,720,472 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	28,758,393 - 28,779,257 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	31,608,641 - 31,629,961 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	31,609,053 - 31,629,881 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	33,532,887 - 33,553,834 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	29,015,659 - 29,036,491 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	29,643,476 - 29,664,308 (-)	NCBI		Celera
RGSC_v3.1	12	28,880,311 - 28,896,981 (-)	NCBI
Cytogenetic Map	12	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

male infertility (ISO)

substance-related disorder (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17alpha-ethynylestradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

cyclosporin A (ISO)

dibutyl phthalate (EXP)

dimethylarsinic acid (EXP)

propanal (ISO)

S-nitrosoglutathione (ISO)

sodium arsenite (ISO)

trichloroethene (EXP)

tunicamycin (ISO)

valproic acid (ISO)

zearalenone (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

piRNA processing (IBA)

piRNA-mediated gene silencing by mRNA destabilization (IEA,ISO)

primary piRNA processing (IEA,ISO)

regulation of translation (IEA)

regulatory ncRNA-mediated gene silencing (IBA,IEA)

sperm DNA condensation (IEA,ISO)

spermatid development (IEA,ISO)

spermatogenesis (IBA,IEA,ISO)

transposable element silencing by piRNA-mediated heterochromatin formation (IEA,ISO)

Cellular Component

chromatoid body (IEA,ISO)

cytoplasm (IEA,ISO)

dense body (IEA,ISO)

nucleus (IBA,IEA,ISO)

P granule (IBA)

Molecular Function

mRNA binding (IEA,ISO)

mRNA cap binding complex binding (IEA,ISO)

nucleic acid binding (IEA)

piRNA binding (IBA,IEA,ISO)

protein binding (ISO)

protein kinase binding (IEA,ISO)

RNA binding (IEA)

RNA endonuclease activity (IBA,IEA,ISO)

single-stranded RNA binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11578866	PMID:12062093	PMID:14736746	PMID:16751776	PMID:16766680	PMID:16787948	PMID:16938833	PMID:20014101	PMID:21539824	PMID:22121019	PMID:22205278	PMID:23328397
PMID:24930433	PMID:26104391	PMID:28254886	PMID:28552346

Genomics

Comparative Map Data

Piwil1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	33,585,747 - 33,606,715 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	33,585,747 - 33,606,591 (-)	Ensembl				GRCr8
mRatBN7.2	12	27,949,743 - 27,970,645 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	27,949,744 - 27,970,580 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	29,089,050 - 29,109,905 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	29,699,619 - 29,720,472 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	28,758,393 - 28,779,257 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	31,608,641 - 31,629,961 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	31,609,053 - 31,629,881 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	33,532,887 - 33,553,834 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	29,015,659 - 29,036,491 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	29,643,476 - 29,664,308 (-)	NCBI		Celera
RGSC_v3.1	12	28,880,311 - 28,896,981 (-)	NCBI
Cytogenetic Map	12	q13	NCBI

PIWIL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	130,337,887 - 130,426,260 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	130,337,887 - 130,372,637 (+)	Ensembl			hg38	GRCh38
GRCh37	12	130,822,432 - 130,857,182 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	129,388,567 - 129,422,826 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	129,347,515 - 129,381,747	NCBI
Celera	12	130,436,876 - 130,471,363 (+)	NCBI		Celera
Cytogenetic Map	12	q24.33	NCBI
HuRef	12	127,807,883 - 127,841,997 (+)	NCBI		HuRef
CHM1_1	12	130,643,298 - 130,677,747 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	130,374,979 - 130,463,542 (+)	NCBI		T2T-CHM13v2.0

Piwil1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	128,813,135 - 128,832,538 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	128,779,588 - 128,832,538 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	128,736,071 - 128,755,474 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	128,702,524 - 128,755,474 (+)	Ensembl			mm10	GRCm38
MGSCv37	5	129,242,121 - 129,261,349 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	129,050,954 - 129,070,182 (+)	NCBI		MGSCv36	mm8
Celera	5	125,768,204 - 125,787,427 (+)	NCBI		Celera
Cytogenetic Map	5	G1.3	NCBI
cM Map	5	67.86	NCBI

Piwil1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955482	1,435,925 - 1,450,857 (-)	Ensembl
ChiLan1.0	NW_004955482	1,435,925 - 1,451,067 (-)	NCBI	ChiLan1.0	ChiLan1.0

PIWIL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	138,398,086 - 138,433,186 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	138,394,605 - 138,429,705 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	127,951,178 - 127,986,173 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	132,169,820 - 132,199,374 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	132,169,820 - 132,199,374 (+)	Ensembl			panPan2	panpan1.1

PIWIL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	1,760,544 - 1,791,204 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	1,761,149 - 1,791,185 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	1,959,935 - 1,990,092 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	2,003,994 - 2,034,410 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	2,003,999 - 2,030,793 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	1,939,796 - 1,967,791 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	2,036,317 - 2,066,550 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	1,946,080 - 1,977,165 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Piwil1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	123,301,659 - 123,323,561 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936660	1,400,212 - 1,418,744 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936660	1,398,640 - 1,418,865 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PIWIL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	24,729,113 - 24,760,320 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	24,729,346 - 24,760,056 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	26,192,428 - 26,219,126 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PIWIL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	125,712,473 - 125,748,280 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	125,717,045 - 125,748,265 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	119,257,698 - 119,295,310 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Piwil1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	27,086,885 - 27,104,011 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624747	27,086,683 - 27,103,223 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Piwil1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	16	25,218,332 - 25,234,717 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Piwil1
143 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	444
Count of miRNA genes:	237
Interacting mature miRNAs:	298
Transcripts:	ENSRNOT00000001238
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	24805022	52308831	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	11200494	52308831	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
8693635	Alc28	Alcohol consumption QTL 28	2.7	0.439	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	50386405	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	25989355	52308831	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	3489416	48489416	Rat
1331739	Hrtrt14	Heart rate QTL 14	3.56232		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	12	1	38687564	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	18473041	52308831	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200497	52308831	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	15264248	52308831	Rat
61331	Eau2	Experimental allergic uveoretinitis QTL 2		0.0005	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	12	1	33700600	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	11743528	52308831	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
2293684	Bmd26	Bone mineral density QTL 26	4.4	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	12	1	38635130	Rat
70169	Eae13	Experimental allergic encephalomyelitis QTL 13		0.032	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	12	29775522	42298555	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	17464979	46784661	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	16187438	52308831	Rat
8693658	Alc33	Alcohol consumption QTL 33	2.1	0.68	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	49212240	Rat
1331787	Rf41	Renal function QTL 41	2.998		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	12	1	33700556	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	16135029	52308831	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	51213550	Rat
1331763	Wbc2	White blood cell count QTL 2	3.162		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	12	11200494	52308831	Rat
61416	Pia4	Pristane induced arthritis QTL 4	8.4		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	12	18749469	36488809	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	11200494	52308831	Rat
7387292	Kidm42	Kidney mass QTL 42	3.03	0.0004	kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	12	1	41361854	Rat
61421	Cia12	Collagen induced arthritis QTL 12	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	18749469	34312613	Rat
1300157	Rf21	Renal function QTL 21	4.4		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	12	29636637	37764351	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2747694	47747694	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	18473041	52308831	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	3087180	48087180	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	5633306	50633306	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	16135029	52308831	Rat
2293086	Iddm30	Insulin dependent diabetes mellitus QTL 30	3.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	7901625	33938215	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
1331755	Bp219	Blood pressure QTL 219	3.041		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	33700556	Rat

Markers in Region

D12Got65

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	12	33,601,650 - 33,601,849 (+)	Marker Load Pipeline
mRatBN7.2	12	27,965,648 - 27,965,847 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	31,624,952 - 31,625,148	NCBI	Rnor6.0
Rnor_5.0	12	33,548,786 - 33,548,982	UniSTS	Rnor5.0
RGSC_v3.4	12	29,031,562 - 29,031,758	UniSTS	RGSC3.4
RGSC_v3.4	12	29,031,561 - 29,031,758	RGD	RGSC3.4
Celera	12	29,659,379 - 29,659,575	UniSTS
RGSC_v3.1	12	28,894,950 - 28,895,146	RGD
RH 3.4 Map	12	464.4	UniSTS
RH 3.4 Map	12	464.4	RGD
Cytogenetic Map	12	q14	UniSTS

UniSTS:498764

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	27,964,862 - 27,965,292 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	31,624,166 - 31,624,595	NCBI	Rnor6.0
Rnor_5.0	12	33,548,000 - 33,548,429	UniSTS	Rnor5.0
RGSC_v3.4	12	29,030,776 - 29,031,205	UniSTS	RGSC3.4
Celera	12	29,658,593 - 29,659,022	UniSTS
Cytogenetic Map	12	q14	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
9	11	34	107	66	65	34	27	34	6	185	84	87	50	63	31	6	6

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108853	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598410	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089632	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000001238 ⟹ ENSRNOP00000001238

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	33,585,747 - 33,606,591 (-)	Ensembl
mRatBN7.2 Ensembl	12	27,949,744 - 27,970,580 (-)	Ensembl
Rnor_6.0 Ensembl	12	31,609,053 - 31,629,881 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115702 ⟹ ENSRNOP00000084832

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	27,951,197 - 27,970,580 (-)	Ensembl

RefSeq Acc Id:

NM_001108853 ⟹ NP_001102323

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	33,585,747 - 33,606,583 (-)	NCBI
mRatBN7.2	12	27,949,743 - 27,970,581 (-)	NCBI
Rnor_6.0	12	31,609,053 - 31,629,881 (-)	NCBI
Rnor_5.0	12	33,532,887 - 33,553,834 (-)	NCBI
RGSC_v3.4	12	29,015,659 - 29,036,491 (-)	RGD
Celera	12	29,643,476 - 29,664,308 (-)	RGD

Sequence:

show sequence

AGAAGCCTGCTGCAGCGACCCGGCGTGAGGAGCCTCAGGGGCTGCGGACCTAAGCGTGCTGAGC
ACGGGGCCAAGATAGGACCAGACGCTGCTGGACCACGACGATCAGGGCGCGACCACACCGGCAT
CCAGCCTGCGACACACGTAGGATTGGAAGGAGGCCAAGCTGAACACCTGAGCTGACTGGAAAAT
GACTGGACGAGCCCGAGCCCGGGCCCGTGGCAGGGCCCGAGGTCAGGAGACGGTGCAGCATGTT
GGGGCTGCTGCAAGCCAGCAACCTGGGTACATCCCGCCGAGACCCCAGCAGTCGCCCACAGAGG
GGGACTTGGTTGGCCGAGGACGACAGAGGGGAATGGTAGTCGGAGCCACGTCCAAGTCACAAGA
ACTGCAGATCTCAGCCGGGTTTCAGGAGCTGTCACTGGCAGAGAGAGGAGGGCGTCGCCGAGAC
TTCCATGACCTTGGTGTGAACACCAGACAGAACCTTGACCATGTCAAAGAGTCAAAGACAGGCT
CCTCTGGCATCATTGTGAAGCTGAGCACCAACCACTTCCGGCTGACCTCGCGCCCACAGTGGGC
CCTGTACCAGTACCACATTGACTATAACCCCCTGATGGAGGCCCGCAGGCTGCGCTCTGCCCTG
CTCTTCCAGCACGAAGACCTCATTGGAAGGTGTCATGCTTTCGACGGGACAATATTGTTTTTAC
CTAAGAGACTACAGCACAAGGTCACGGAAGTATTCAGTCAGACTCGGAATGGGGAACACGTGCG
GATTACCATCACCCTGACCAACGAGCTGCCGCCCACCTCACCCACCTGCCTGCAGTTCTATAAC
ATCATCTTCAGGAGGCTCTTGAAAATCATGAATTTGCAACAAATTGGACGGAATTATTACAACC
CAAGTGACCCGATTGATATTCCAAATCACAGGTTGGTGATCTGGCCCGGCTTCACCACCTCCAT
ACTTCAATATGAGAACAACATCATGCTTTGCACAGACGTCAGCCACAAGGTCCTCCGCAGCGAG
ACCGTTCTAGACTTCATGTTCAATCTGTACCAGCAGACGGAGGAGCACAAGTTCCAGGAGCAAG
TGTCCAAGGAGCTCATAGGCCTCATCGTCCTCACCAAGTACAACAACAAGACCTACAGGGTGGA
TGACATCGACTGGGACCAGAATCCAAAGAGCACCTTCAAGAAGGCAGATGGCTCGGAGGTCAGC
TTCCTGGAGTACTACAGGAAGCAATACAACCAGGAGATCACAGACTTGAAGCAGCCAGTGCTAG
TGAGCCAGCCCAAGCGGAGGAGAGGCCCTGGCGGCACCCTGCCTGGCCCAGCCATGCTCATCCC
AGAGCTCTGCTACCTCACAGGCCTGACTGATAAAATGCGCAATGATTTCAACGTGATGAAGGAC
CTGGCGGTGCACACACGGCTGACCCCTGAGCAGCGGCAGCGGGAGGTGGGCCGCCTCATCGACT
ACATCCACAAGGATGACAATGTGCAGAGAGAGCTTCGAGACTGGGGCCTAAGCTTCGATTCGAA
CTTGCTGTCCTTCTCAGGAAGAATCTTACAATCCGAGAAGATCCACCAGGGTGGAAAGACGTTT
GATTACAACCCACAATTTGCAGACTGGTCCAAAGAAACGAGAGGCGCGCCGCTGATCAGCGTGA
AGCCGTTGGATAACTGGCTGCTGATCTATACCCGCAGGAATTATGAAGCGGCCAACTCGCTGAT
ACAGAACCTGTTCAAAGTGACTCCGGCCATGGGCATCCAGATGAAAAAGGCCATCATGATCGAG
GTGGACGACAGAACAGAAGCTTATCTGAGAGCCTTGCAGCAGAAGGTGACATCAGACACTCAGA
TAGTTGTCTGTCTCTTGTCAAGTAATCGGAAGGACAAGTATGATGCCATCAAGAAGTATTTGTG
CACAGACTGCCCCACCCCAAGTCAGTGTGTGGTGGCCCGGACGCTGGGCAAGCAGCAAACAGTC
ATGGCCATTGCCACCAAGATCGCCCTGCAGATGAACTGCAAGATGGGAGGCGAGCTCTGGCGGG
TGGACATGCCTCTGAAGCTGGCAATGATCGTGGGCATTGACTGTTACCATGACACCACAGCTGG
GCGGAGGTCCATCGCAGGATTCGTTGCCAGCATCAATGAAGGGATGACCCGTTGGTTCTCCCGC
TGCGTCTTTCAGGACCGTGGACAGGAGCTGGTAGACGGTCTGAAGGTGTGCTTGCAAGCTGCCC
TGAGGGCTTGGAGTGGCTGCAATGAATATATGCCCAGCCGAGTCATTGTGTACCGAGACGGTGT
GGGGGACGGGCAGCTGAAGACCCTGGTCAATTATGAGGTCCCACAGTTCCTAGACTGCCTCAAG
TCAGTCGGGAGAGGTTACAACCCAAGACTGACCGTGATCGTAGTGAAGAAGCGAGTCAATGCCA
GGTTTTTTGCTCAGTCTGGGGGAAGACTTCAGAACCCTCTTCCGGGGACAGTCATCGATGTGGA
AGTCACCAGACCAGAGTGGTATGACTTTTTCATCGTGAGCCAGGCAGTGAGAAGTGGGAGTGTG
TCCCCAACACACTACAATGTCATCTACGACAGCAGTGGCCTGAAGCCCGACCACATCCAGCGGC
TGACGTACAAGCTGTGTCACGTGTACTACAATTGGCCTGGAGTCATCCGAGTCCCTGCACCTTG
CCAGTATGCACACAAGCTGGCCTTCCTCGTGGGCCAGAGCATCCACAGAGAGCCGAACCTCTCC
CTGTCCAACCGTCTCTACTACCTCTAACCAGCAGCGAGGGCCTACATGCTGGTTTCCTCCAGAG
CTCTGCCAACCTTTAGTTCTGTTTCTCATATGATGTTGTTCTAGCGGGATGCTGGGGGTGGGGG
TTGGGGGCCGCGGTTTCGTTTTTTTTTTTTTTTTTTAGTTGGTTTGTAGTGGTTATAGAGTTAA
CTAAGGTTCACTGTTTGCTTTGTTTCTCATAGAGCGTTGTGACAATTTGCTTGGCAGAGTGGTG
GCAGGGGGCCGTGGTACCACAGATAGACTTTCCTAAAGCAGCCGAGTCGGCAGCTGCGCTCTCT
CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGCATGTTTGAATTTAAAGGA
GGAAAAGACGCAAGGCAAAAATACCCAGAGCATCCTAGGCTGATGCTATGTGGGACTCTGACCC
TCTGACACCTCAGATCCTAAAGATAAAAAGGCCGGGGGTGCCTCTCTGAATTTCTTTTAAGAGT
TAGGTTATAGGGAATGAAAAGAATTGTTGAGGGTTGGGGATTTAGCTCAGTGGTAGAGCGCTTG
CCTAGCAAGCGCAAGGCCCTGGGTTCGGTCCCCAGCTCCGAAAAAAAAGAAAAAAGAAAAAAAA
ATAATAATTGTTGAAAGTTTTAAACTTTTCTCCATGAAAGTGTTTTAAGACTGATGAGGCCGGT
GGTGGAACGAGTGTTGTTTTCTTTCGCAATTTTCTCACCGAGTGAAATTAGCGACCCTCACTTT
ATTTAAACAGTTTTTAGTTTTCGAAGGCCCGTGTTTTCTTTGTTTTTAAACTGCAGAAGACCAC
TCTGGGATAGGATTCCACTCCCGAAAGTAAGGTGTCGGGCGTGGTGGCACACACCTGTGATCTC
AGCACTTGGGAGGTGAAGCCCGGGGAACCCCAAGTTCCCGGTCAGCCTAGGCTACATAGTGAGA
CCTTGTCTTAACAAACAGGAAAATAAAAGAAAAATGGAGCAGTTATGAGTTATGGGTGTCAGTT
TCTGCAGGAGACTCTGGGAGTAAGAGCTGCCCCTGTCCCCAGAGGCAGCTGGTGGGCCAATTCA
GGTGCCAGGCAAGGTATGGCCACATATGTTTGTCTGGCTCTTTGGCAGTGAAGGAGGCTTGGAG
TTATGTCACGAGAGCAGCTTGAAGTGGCTACAGTGTGATGAGTTTTACACAATGGCAGTGTGTG
CCCCCGGCACAGCTCAATAAAGTTTCTGTCTCACTTT

hide sequence

RefSeq Acc Id:

XM_017598410 ⟹ XP_017453899

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	33,585,747 - 33,606,715 (-)	NCBI
mRatBN7.2	12	27,949,743 - 27,970,645 (-)	NCBI
Rnor_6.0	12	31,610,223 - 31,629,961 (-)	NCBI

Sequence:

show sequence

GATCTGGCAGTTGGGGCTGTTAGCAGGTGCCCGCGGGAGGTGCAGCAGCAGTGCGAGGTGGTGG
CAGCCCTGCGCCCGCGAGAAGCCTGCTGCAGCGACCCGGCGTGAGGAGCCTCAGGGGCTGCGGA
CCTAAGCGTGCTGAGCACGGGGCCAAGATAGGACCAGACGCTGCTGGACCACGACGATCAGGGC
GCGACCACACCGGCATCCAGCCTGCGACACACGTAGGATTGGAAGGAGGCCAAGCTGAACACCT
GAGCTGACTGGAAAATGACTGGACGAGCCCGAGCCCGGGCCCGTGGCAGGGCCCGAGGTCAGGA
GACGGTGCAGCATGTTGGGGCTGCTGCACAGAGCCAGCAACCTGGGTACATCCCGCCGAGACCC
CAGCAGTCGCCCACAGAGGGGGACTTGGTTGGCCGAGGACGACAGAGGGGAATGGTAGTCGGAG
CCACGTCCAAGTCACAAGAACTGCAGATCTCAGCCGGGTTTCAGGAGCTGTCACTGGCAGAGAG
AGGAGGGCGTCGCCGAGACTTCCATGACCTTGGTGTGAACACCAGACAGAACCTTGACCATGTC
AAAGAGTCAAAGACAGGCTCCTCTGGCATCATTGTGAAGCTGAGCACCAACCACTTCCGGCTGA
CCTCGCGCCCACAGTGGGCCCTGTACCAGTACCACATTGACTATAACCCCCTGATGGAGGCCCG
CAGGCTGCGCTCTGCCCTGCTCTTCCAGCACGAAGACCTCATTGGAAGGTGTCATGCTTTCGAC
GGGACAATATTGTTTTTACCTAAGAGACTACAGCACAAGGTCACGGAAGTATTCAGTCAGACTC
GGAATGGGGAACACGTGCGGATTACCATCACCCTGACCAACGAGCTGCCGCCCACCTCACCCAC
CTGCCTGCAGTTCTATAACATCATCTTCAGGAGGCTCTTGAAAATCATGAATTTGCAACAAATT
GGACGGAATTATTACAACCCAAGTGACCCGATTGATATTCCAAATCACAGGTTGGTGATCTGGC
CCGGCTTCACCACCTCCATACTTCAATATGAGAACAACATCATGCTTTGCACAGACGTCAGCCA
CAAGGTCCTCCGCAGCGAGACCGTTCTAGACTTCATGTTCAATCTGTACCAGCAGACGGAGGAG
CACAAGTTCCAGGAGCAAGTGTCCAAGGAGCTCATAGGCCTCATCGTCCTCACCAAGTACAACA
ACAAGACCTACAGGGTGGATGACATCGACTGGGACCAGAATCCAAAGAGCACCTTCAAGAAGGC
AGATGGCTCGGAGGTCAGCTTCCTGGAGTACTACAGGAAGCAATACAACCAGGAGATCACAGAC
TTGAAGCAGCCAGTGCTAGTGAGCCAGCCCAAGCGGAGGAGAGGCCCTGGCGGCACCCTGCCTG
GCCCAGCCATGCTCATCCCAGAGCTCTGCTACCTCACAGGCCTGACTGATAAAATGCGCAATGA
TTTCAACGTGATGAAGGACCTGGCGGTGCACACACGGCTGACCCCTGAGCAGCGGCAGCGGGAG
GTGGGCCGCCTCATCGACTACATCCACAAGGATGACAATGTGCAGAGAGAGCTTCGAGACTGGG
GCCTAAGCTTCGATTCGAACTTGCTGTCCTTCTCAGGAAGAATCTTACAATCCGAGAAGATCCA
CCAGGGTGGAAAGACGTTTGATTACAACCCACAATTTGCAGACTGGTCCAAAGAAACGAGAGGC
GCGCCGCTGATCAGCGTGAAGCCGTTGGATAACTGGCTGCTGATCTATACCCGCAGGAATTATG
AAGCGGCCAACTCGCTGATACAGAACCTGTTCAAAGTGACTCCGGCCATGGGCATCCAGATGAA
AAAGGCCATCATGATCGAGGTGGACGACAGAACAGAAGCTTATCTGAGAGCCTTGCAGCAGAAG
GTGACATCAGACACTCAGATAGTTGTCTGTCTCTTGTCAAGTAATCGGAAGGACAAGTATGATG
CCATCAAGAAGTATTTGTGCACAGACTGCCCCACCCCAAGTCAGTGTGTGGTGGCCCGGACGCT
GGGCAAGCAGCAAACAGTCATGGCCATTGCCACCAAGATCGCCCTGCAGATGAACTGCAAGATG
GGAGGCGAGCTCTGGCGGGTGGACATGCCTCTGAAGCTGGCAATGATCGTGGGCATTGACTGTT
ACCATGACACCACAGCTGGGCGGAGGTCCATCGCAGGATTCGTTGCCAGCATCAATGAAGGGAT
GACCCGTTGGTTCTCCCGCTGCGTCTTTCAGGACCGTGGACAGGAGCTGGTAGACGGTCTGAAG
GTGTGCTTGCAAGCTGCCCTGAGGGCTTGGAGTGGCTGCAATGAATATATGCCCAGCCGAGTCA
TTGTGTACCGAGACGGTGTGGGGGACGGGCAGCTGAAGACCCTGGTCAATTATGAGGTCCCACA
GTTCCTAGACTGCCTCAAGTCAGTCGGGAGAGGTTACAACCCAAGACTGACCGTGATCGTAGTG
AAGAAGCGAGTCAATGCCAGGTTTTTTGCTCAGTCTGGGGGAAGACTTCAGAACCCTCTTCCGG
GGACAGTCATCGATGTGGAAGTCACCAGACCAGAGTGGTATGACTTTTTCATCGTGAGCCAGGC
AGTGAGAAGTGGGAGTGTGTCCCCAACACACTACAATGTCATCTACGACAGCAGTGGCCTGAAG
CCCGACCACATCCAGCGGCTGACGTACAAGCTGTGTCACGTGTACTACAATTGGCCTGGAGTCA
TCCGAGTCCCTGCACCTTGCCAGTATGCACACAAGCTGGCCTTCCTCGTGGGCCAGAGCATCCA
CAGAGAGCCGAACCTCTCCCTGTCCAACCGTCTCTACTACCTCTAACCAGCAGCGAGGGCCTAC
ATGCTGGTTTCCTCCAGAGCTCTGCCAACCTTTAGTTCTGTTTCTCATATGATGTTGTTCTAGC
GGGATGCTGGGGG

hide sequence

RefSeq Acc Id:

XM_039089632 ⟹ XP_038945560

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	33,585,747 - 33,606,715 (-)	NCBI
mRatBN7.2	12	27,949,743 - 27,970,456 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102323	(Get FASTA)	NCBI Sequence Viewer
	XP_017453899	(Get FASTA)	NCBI Sequence Viewer
	XP_038945560	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM13523	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000001238
	ENSRNOP00000001238.5

RefSeq Acc Id:

NP_001102323 ⟸ NM_001108853

- UniProtKB:

D3ZTP9 (UniProtKB/TrEMBL), A6J0T4 (UniProtKB/TrEMBL), A0A8I6A0Y7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTGRARARARGRARGQETVQHVGAAASQQPGYIPPRPQQSPTEGDLVGRGRQRGMVVGATSKSQ
ELQISAGFQELSLAERGGRRRDFHDLGVNTRQNLDHVKESKTGSSGIIVKLSTNHFRLTSRPQW
ALYQYHIDYNPLMEARRLRSALLFQHEDLIGRCHAFDGTILFLPKRLQHKVTEVFSQTRNGEHV
RITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPSDPIDIPNHRLVIWPGFTTS
ILQYENNIMLCTDVSHKVLRSETVLDFMFNLYQQTEEHKFQEQVSKELIGLIVLTKYNNKTYRV
DDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLI
PELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKDDNVQRELRDWGLSFDS
NLLSFSGRILQSEKIHQGGKTFDYNPQFADWSKETRGAPLISVKPLDNWLLIYTRRNYEAANSL
IQNLFKVTPAMGIQMKKAIMIEVDDRTEAYLRALQQKVTSDTQIVVCLLSSNRKDKYDAIKKYL
CTDCPTPSQCVVARTLGKQQTVMAIATKIALQMNCKMGGELWRVDMPLKLAMIVGIDCYHDTTA
GRRSIAGFVASINEGMTRWFSRCVFQDRGQELVDGLKVCLQAALRAWSGCNEYMPSRVIVYRDG
VGDGQLKTLVNYEVPQFLDCLKSVGRGYNPRLTVIVVKKRVNARFFAQSGGRLQNPLPGTVIDV
EVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDSSGLKPDHIQRLTYKLCHVYYNWPGVIRVPAP
CQYAHKLAFLVGQSIHREPNLSLSNRLYYL

hide sequence

RefSeq Acc Id:	XP_017453899 ⟸ XM_017598410
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6A0Y7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTGRARARARGRARGQETVQHVGAAAQSQQPGYIPPRPQQSPTEGDLVGRGRQRGMVVGATSKS QELQISAGFQELSLAERGGRRRDFHDLGVNTRQNLDHVKESKTGSSGIIVKLSTNHFRLTSRPQ WALYQYHIDYNPLMEARRLRSALLFQHEDLIGRCHAFDGTILFLPKRLQHKVTEVFSQTRNGEH VRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPSDPIDIPNHRLVIWPGFTT SILQYENNIMLCTDVSHKVLRSETVLDFMFNLYQQTEEHKFQEQVSKELIGLIVLTKYNNKTYR VDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAML IPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKDDNVQRELRDWGLSFD SNLLSFSGRILQSEKIHQGGKTFDYNPQFADWSKETRGAPLISVKPLDNWLLIYTRRNYEAANS LIQNLFKVTPAMGIQMKKAIMIEVDDRTEAYLRALQQKVTSDTQIVVCLLSSNRKDKYDAIKKY LCTDCPTPSQCVVARTLGKQQTVMAIATKIALQMNCKMGGELWRVDMPLKLAMIVGIDCYHDTT AGRRSIAGFVASINEGMTRWFSRCVFQDRGQELVDGLKVCLQAALRAWSGCNEYMPSRVIVYRD GVGDGQLKTLVNYEVPQFLDCLKSVGRGYNPRLTVIVVKKRVNARFFAQSGGRLQNPLPGTVID VEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDSSGLKPDHIQRLTYKLCHVYYNWPGVIRVPA PCQYAHKLAFLVGQSIHREPNLSLSNRLYYL hide sequence

Ensembl Acc Id:

ENSRNOP00000001238 ⟸ ENSRNOT00000001238

RefSeq Acc Id:	XP_038945560 ⟸ XM_039089632
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6A0Y7 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000084832 ⟸ ENSRNOT00000115702

Protein Domains

PAZ Piwi

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZTP9-F1-model_v2	AlphaFold	D3ZTP9	1-862	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698595

Promoter ID:

EPDNEW_R9120

Type:

initiation region

Name:

Piwil1_1

Description:

piwi-like RNA-mediated gene silencing 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	31,629,953 - 31,630,013	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306980	AgrOrtholog
BioCyc Gene	G2FUF-19466	BioCyc
Ensembl Genes	ENSRNOG00000000934	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000001238	ENTREZGENE
	ENSRNOT00000001238.7	UniProtKB/TrEMBL
Gene3D-CATH	3.30.420.10	UniProtKB/TrEMBL
	3.40.50.2300	UniProtKB/TrEMBL
	paz domain	UniProtKB/TrEMBL
InterPro	ArgoL1	UniProtKB/TrEMBL
	GAGE	UniProtKB/TrEMBL
	PAZ	UniProtKB/TrEMBL
	PAZ_dom_sf	UniProtKB/TrEMBL
	Piwi	UniProtKB/TrEMBL
	PolynucTfrase_RNaseH_fold	UniProtKB/TrEMBL
	RNaseH_sf	UniProtKB/TrEMBL
KEGG Report	rno:363912	UniProtKB/TrEMBL
NCBI Gene	363912	ENTREZGENE
PANTHER	EUKARYOTIC TRANSLATION INITIATION FACTOR 2C	UniProtKB/TrEMBL
Pfam	ArgoL1	UniProtKB/TrEMBL
	GAGE	UniProtKB/TrEMBL
	PAZ	UniProtKB/TrEMBL
	Piwi	UniProtKB/TrEMBL
	Piwi_N	UniProtKB/TrEMBL
PhenoGen	Piwil1	PhenoGen
PROSITE	PAZ	UniProtKB/TrEMBL
	PIWI	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000000934	RatGTEx
SMART	GAGE	UniProtKB/TrEMBL
	PAZ	UniProtKB/TrEMBL
	Piwi	UniProtKB/TrEMBL
Superfamily-SCOP	PAZ	UniProtKB/TrEMBL
	RNaseH_fold	UniProtKB/TrEMBL
UniProt	A0A8I6A0Y7	ENTREZGENE
	A6J0T4	ENTREZGENE, UniProtKB/TrEMBL
	D3ZTP9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-02-27	Piwil1	piwi-like RNA-mediated gene silencing 1	Piwil1	piwi-like 1 (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-09	Piwil1	piwi-like 1 (Drosophila)	Piwil1	piwi like homolog 1 (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Piwil1	piwi like homolog 1 (Drosophila)	Piwil1_predicted	piwi like homolog 1 (Drosophila) (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Piwil1_predicted	piwi like homolog 1 (Drosophila) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD