Suv39h2 (SUV39H2 histone lysine methyltransferase) - Rat Genome Database

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Gene: Suv39h2 (SUV39H2 histone lysine methyltransferase) Rattus norvegicus
Analyze
Symbol: Suv39h2
Name: SUV39H2 histone lysine methyltransferase
RGD ID: 1306969
Description: Predicted to enable several functions, including cation binding activity; histone H3K9me2 methyltransferase activity; and ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in several processes, including epigenetic regulation of gene expression; male meiotic nuclear division; and negative regulation of DNA-templated transcription. Predicted to act upstream of or within cellular response to hypoxia and negative regulation of transcription by RNA polymerase II. Predicted to be located in heterochromatin. Predicted to be active in nucleus. Orthologous to human SUV39H2 (SUV39H2 histone lysine methyltransferase); PARTICIPATES IN histone modification pathway; homocysteine metabolic pathway; methionine cycle/metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; decabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: histone-lysine N-methyltransferase SUV39H2; LOC364785; suppressor of variegation 3-9 homolog 2; suppressor of variegation 3-9 homolog 2 (Drosophila)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81779,665,467 - 79,684,492 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1779,665,376 - 79,684,492 (+)EnsemblGRCr8
mRatBN7.21774,756,290 - 74,775,332 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1774,756,306 - 74,775,332 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1778,209,501 - 78,228,542 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01782,057,802 - 82,076,828 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01776,092,937 - 76,111,981 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01778,762,897 - 78,782,016 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1778,762,991 - 78,782,016 (+)Ensemblrn6Rnor6.0
Rnor_5.01780,406,940 - 80,425,965 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41785,875,954 - 85,894,979 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1774,141,962 - 74,160,987 (+)NCBICelera
RGSC_v3.11785,886,805 - 85,903,145 (+)NCBI
Cytogenetic Map17q12.3NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
cylindrospermopsin  (ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
FR900359  (ISO)
glycerol 2-phosphate  (ISO)
GSK-J4  (ISO)
hydrogen peroxide  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
methylmercury chloride  (ISO)
nickel atom  (ISO)
nitric oxide  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
succimer  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Histone lysine methylation dynamics: establishment, regulation, and biological impact. Black JC, etal., Mol Cell. 2012 Nov 30;48(4):491-507. doi: 10.1016/j.molcel.2012.11.006.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Targeting protein lysine methylation and demethylation in cancers. He Y, etal., Acta Biochim Biophys Sin (Shanghai). 2012 Jan;44(1):70-9. doi: 10.1093/abbs/gmr109.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression. O'Carroll D, etal., Mol Cell Biol 2000 Dec;20(24):9423-33.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:10949293   PMID:15788566   PMID:20084102   PMID:21402781   PMID:23451023   PMID:24413057  


Genomics

Comparative Map Data
Suv39h2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81779,665,467 - 79,684,492 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1779,665,376 - 79,684,492 (+)EnsemblGRCr8
mRatBN7.21774,756,290 - 74,775,332 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1774,756,306 - 74,775,332 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1778,209,501 - 78,228,542 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01782,057,802 - 82,076,828 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01776,092,937 - 76,111,981 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01778,762,897 - 78,782,016 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1778,762,991 - 78,782,016 (+)Ensemblrn6Rnor6.0
Rnor_5.01780,406,940 - 80,425,965 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41785,875,954 - 85,894,979 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1774,141,962 - 74,160,987 (+)NCBICelera
RGSC_v3.11785,886,805 - 85,903,145 (+)NCBI
Cytogenetic Map17q12.3NCBI
SUV39H2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381014,878,866 - 14,904,315 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1014,878,820 - 14,904,315 (+)Ensemblhg38GRCh38
GRCh371014,920,865 - 14,946,314 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361014,960,905 - 14,986,320 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341014,960,904 - 14,986,308NCBI
Celera1014,848,822 - 14,874,354 (+)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1014,831,341 - 14,856,796 (+)NCBIHuRef
CHM1_11014,921,216 - 14,946,434 (+)NCBICHM1_1
T2T-CHM13v2.01014,892,831 - 14,918,279 (+)NCBIT2T-CHM13v2.0
Suv39h2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3923,456,852 - 3,476,085 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl23,456,852 - 3,476,068 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3823,455,815 - 3,474,986 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl23,455,815 - 3,475,031 (-)Ensemblmm10GRCm38
MGSCv3723,373,087 - 3,392,258 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3623,373,092 - 3,392,235 (-)NCBIMGSCv36mm8
Celera23,406,803 - 3,425,973 (-)NCBICelera
Cytogenetic Map2A1NCBI
cM Map21.95NCBI
Suv39h2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542919,503,197 - 19,528,027 (-)Ensembl
ChiLan1.0NW_00495542919,503,197 - 19,526,454 (-)NCBIChiLan1.0ChiLan1.0
SUV39H2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2827,404,606 - 27,429,895 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11027,409,940 - 27,435,229 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01014,882,491 - 14,907,724 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11015,211,360 - 15,236,272 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1015,211,360 - 15,237,097 (+)EnsemblpanPan2panpan1.1
SUV39H2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1221,715,677 - 21,749,732 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl221,728,964 - 21,749,597 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha218,828,959 - 18,863,033 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0222,017,081 - 22,051,385 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl222,029,347 - 22,051,353 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1219,228,679 - 19,251,776 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0220,052,418 - 20,086,507 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0220,679,024 - 20,713,098 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Suv39h2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093446,893,110 - 6,922,105 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366131,443,629 - 1,467,229 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366131,443,663 - 1,467,776 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SUV39H2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1046,873,126 - 46,900,040 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11046,874,606 - 46,900,058 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21051,595,641 - 51,633,086 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SUV39H2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1914,900,503 - 14,924,017 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl914,900,945 - 14,923,447 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605120,439,417 - 20,464,204 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Suv39h2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624805597,406 - 618,969 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624805594,986 - 619,115 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Suv39h2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1149,911,302 - 9,928,870 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Suv39h2
191 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:269
Count of miRNA genes:190
Interacting mature miRNAs:220
Transcripts:ENSRNOT00000020924
Prediction methods:Miranda, Pita, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172413612784432719Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)174238816487388164Rat
631502Cm26Cardiac mass QTL 263.71heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)177061350286062352Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175819406487388164Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)173803135483031354Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)175482950393515804Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174096801789341781Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172723344583975845Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)173803135483031354Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172439059584432719Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)173803135483031354Rat
61466Niddm12Non-insulin dependent diabetes mellitus QTL 123.20.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)176515487293515804Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173803135483031354Rat
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)174238816487388164Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)174605012691050126Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175560459793006569Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)174265489587654895Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)173768787782687877Rat
1300131Bp193Blood pressure QTL 1933.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176855004093515804Rat
7488963Bp369Blood pressure QTL 3690.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176369714782818564Rat
1300129Rf25Renal function QTL 253.03blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)174106235286062352Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172413612784432719Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173219953486201342Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2413612784432719Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172413612784432719Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173604553781045537Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)176456982086954580Rat

Markers in Region
RH133530  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21774,773,483 - 74,773,677 (+)MAPPERmRatBN7.2
Rnor_6.01778,780,168 - 78,780,361NCBIRnor6.0
Rnor_5.01780,424,117 - 80,424,310UniSTSRnor5.0
RGSC_v3.41785,893,131 - 85,893,324UniSTSRGSC3.4
Celera1774,159,139 - 74,159,332UniSTS
RH 3.4 Map17758.1UniSTS
Cytogenetic Map17q12.3UniSTS
ksks283  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21774,766,817 - 74,767,142 (+)MAPPERmRatBN7.2
Rnor_6.01778,773,503 - 78,773,827NCBIRnor6.0
Rnor_5.01780,417,452 - 80,417,776UniSTSRnor5.0
RGSC_v3.41785,886,466 - 85,886,790UniSTSRGSC3.4
Celera1774,152,474 - 74,152,798UniSTS
Cytogenetic Map17q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 66 164 91 90 59 90 59 6 351 189 11 143 79 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000020924   ⟹   ENSRNOP00000020924
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1779,665,467 - 79,684,492 (+)Ensembl
mRatBN7.2 Ensembl1774,756,306 - 74,775,332 (+)Ensembl
Rnor_6.0 Ensembl1778,762,991 - 78,782,016 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077953   ⟹   ENSRNOP00000072847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1778,764,506 - 78,779,545 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102582   ⟹   ENSRNOP00000096548
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1779,665,467 - 79,684,492 (+)Ensembl
mRatBN7.2 Ensembl1774,756,306 - 74,775,332 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000144553   ⟹   ENSRNOP00000106598
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1779,665,376 - 79,684,492 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000147697   ⟹   ENSRNOP00000104997
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1779,666,410 - 79,684,492 (+)Ensembl
RefSeq Acc Id: NM_001108883   ⟹   NP_001102353
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81779,665,467 - 79,684,492 (+)NCBI
mRatBN7.21774,756,306 - 74,775,332 (+)NCBI
Rnor_6.01778,762,991 - 78,782,016 (+)NCBI
Rnor_5.01780,406,940 - 80,425,965 (+)NCBI
RGSC_v3.41785,875,954 - 85,894,979 (+)RGD
Celera1774,141,962 - 74,160,987 (+)RGD
Sequence:
RefSeq Acc Id: XM_039095983   ⟹   XP_038951911
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81779,665,486 - 79,681,915 (+)NCBI
mRatBN7.21774,756,290 - 74,773,743 (+)NCBI
RefSeq Acc Id: XM_063276676   ⟹   XP_063132746
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81779,666,284 - 79,681,915 (+)NCBI
RefSeq Acc Id: NP_001102353   ⟸   NM_001108883
- UniProtKB: D3ZIH5 (UniProtKB/TrEMBL),   A6JM14 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072847   ⟸   ENSRNOT00000077953
Ensembl Acc Id: ENSRNOP00000020924   ⟸   ENSRNOT00000020924
RefSeq Acc Id: XP_038951911   ⟸   XM_039095983
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000096548   ⟸   ENSRNOT00000102582
RefSeq Acc Id: XP_063132746   ⟸   XM_063276676
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000106598   ⟸   ENSRNOT00000144553
Ensembl Acc Id: ENSRNOP00000104997   ⟸   ENSRNOT00000147697
Protein Domains
Chromo   Post-SET   Pre-SET   SET

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZIH5-F1-model_v2 AlphaFold D3ZIH5 1-481 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700581
Promoter ID:EPDNEW_R11105
Type:multiple initiation site
Name:Suv39h2_1
Description:suppressor of variegation 3-9 homolog 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01778,763,001 - 78,763,061EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306969 AgrOrtholog
BioCyc Gene G2FUF-8649 BioCyc
Ensembl Genes ENSRNOG00000015585 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020924 ENTREZGENE
  ENSRNOT00000020924.6 UniProtKB/TrEMBL
  ENSRNOT00000102582.2 UniProtKB/TrEMBL
  ENSRNOT00000144553 ENTREZGENE
  ENSRNOT00000144553.1 UniProtKB/TrEMBL
  ENSRNOT00000147697 ENTREZGENE
  ENSRNOT00000147697.1 UniProtKB/TrEMBL
Gene3D-CATH 2.170.270.10 UniProtKB/TrEMBL
  2.40.50.40 UniProtKB/TrEMBL
InterPro Chromo_domain UniProtKB/TrEMBL
  Chromo_domain/shadow UniProtKB/TrEMBL
  Chromodomain-like UniProtKB/TrEMBL
  Chromodomain_CS UniProtKB/TrEMBL
  H3K9_Histone-Lys_N-MTase UniProtKB/TrEMBL
  Histone_H3-K9_MeTrfase UniProtKB/TrEMBL
  Post-SET_dom UniProtKB/TrEMBL
  Pre-SET_dom UniProtKB/TrEMBL
  SET_dom UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/TrEMBL
KEGG Report rno:364785 UniProtKB/TrEMBL
NCBI Gene 364785 ENTREZGENE
PANTHER HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H UniProtKB/TrEMBL
  HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H2 UniProtKB/TrEMBL
Pfam Chromo UniProtKB/TrEMBL
  Pre-SET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
PhenoGen Suv39h2 PhenoGen
PIRSF SUV39_SET UniProtKB/TrEMBL
PROSITE CHROMO_1 UniProtKB/TrEMBL
  CHROMO_2 UniProtKB/TrEMBL
  POST_SET UniProtKB/TrEMBL
  PRE_SET UniProtKB/TrEMBL
  SAM_MT43_SUVAR39_3 UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015585 RatGTEx
SMART CHROMO UniProtKB/TrEMBL
  PostSET UniProtKB/TrEMBL
  PreSET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
Superfamily-SCOP Chromodomain-like UniProtKB/TrEMBL
  SSF82199 UniProtKB/TrEMBL
UniProt A0A8I6GM48_RAT UniProtKB/TrEMBL
  A0ABK0LKG9_RAT UniProtKB/TrEMBL
  A0ABK0LW82_RAT UniProtKB/TrEMBL
  A6JM14 ENTREZGENE, UniProtKB/TrEMBL
  D3ZIH5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-08-24 Suv39h2  SUV39H2 histone lysine methyltransferase  Suv39h2  suppressor of variegation 3-9 homolog 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-12-09 Suv39h2  suppressor of variegation 3-9 homolog 2  Suv39h2  suppressor of variegation 3-9 homolog 2 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Suv39h2  suppressor of variegation 3-9 homolog 2 (Drosophila)   Suv39h2_predicted  suppressor of variegation 3-9 homolog 2 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Suv39h2_predicted  suppressor of variegation 3-9 homolog 2 (Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED