Donson (DNA replication fork stabilization factor DONSON) - Rat Genome Database

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Gene: Donson (DNA replication fork stabilization factor DONSON) Rattus norvegicus
Analyze
Symbol: Donson
Name: DNA replication fork stabilization factor DONSON
RGD ID: 1306823
Description: Predicted to be involved in DNA-templated DNA replication and mitotic G2/M transition checkpoint. Predicted to be located in replication fork. Predicted to be part of replisome. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in microcephaly, short stature, and limb abnormalities and microcephaly-micromelia syndrome. Orthologous to human DONSON (DNA replication fork stabilization factor DONSON); INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; acetamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: downstream neighbor of SON; LOC288257; MGC94546; protein downstream neighbor of Son
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81144,405,794 - 44,419,099 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1144,405,804 - 44,418,791 (-)EnsemblGRCr8
mRatBN7.21130,919,834 - 30,933,150 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1130,923,239 - 30,932,889 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1139,613,755 - 39,626,757 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01132,285,188 - 32,298,190 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01131,450,393 - 31,463,308 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01131,834,608 - 31,847,751 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1131,837,839 - 31,847,490 (-)Ensemblrn6Rnor6.0
Rnor_5.01135,443,360 - 35,456,223 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41131,652,219 - 31,661,872 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1130,590,666 - 30,600,291 (-)NCBICelera
RGSC_v3.11131,691,277 - 31,700,929 (-)NCBI
Cytogenetic Map11q11NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA,IEA,ISO)
replication fork  (IEA,ISO)
replisome  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:16778019   PMID:28191891  


Genomics

Comparative Map Data
Donson
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81144,405,794 - 44,419,099 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1144,405,804 - 44,418,791 (-)EnsemblGRCr8
mRatBN7.21130,919,834 - 30,933,150 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1130,923,239 - 30,932,889 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1139,613,755 - 39,626,757 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01132,285,188 - 32,298,190 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01131,450,393 - 31,463,308 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01131,834,608 - 31,847,751 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1131,837,839 - 31,847,490 (-)Ensemblrn6Rnor6.0
Rnor_5.01135,443,360 - 35,456,223 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41131,652,219 - 31,661,872 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1130,590,666 - 30,600,291 (-)NCBICelera
RGSC_v3.11131,691,277 - 31,700,929 (-)NCBI
Cytogenetic Map11q11NCBI
DONSON
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382133,577,551 - 33,588,684 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2133,559,542 - 33,589,015 (-)Ensemblhg38GRCh38
GRCh372134,949,857 - 34,960,990 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362133,872,081 - 33,882,884 (-)NCBIBuild 36Build 36hg18NCBI36
Celera2120,149,845 - 20,160,634 (-)NCBICelera
Cytogenetic Map21q22.11NCBI
HuRef2120,428,274 - 20,439,407 (-)NCBIHuRef
CHM1_12134,512,501 - 34,523,651 (-)NCBICHM1_1
T2T-CHM13v2.02131,959,392 - 31,970,473 (-)NCBIT2T-CHM13v2.0
Donson
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391691,463,744 - 91,485,702 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1691,473,696 - 91,485,658 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381691,666,856 - 91,688,932 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1691,676,808 - 91,688,770 (-)Ensemblmm10GRCm38
MGSCv371691,679,510 - 91,688,973 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361691,568,124 - 91,577,587 (-)NCBIMGSCv36mm8
Celera1692,757,855 - 92,767,320 (-)NCBICelera
Cytogenetic Map16C3.3- C4NCBI
cM Map1653.25NCBI
Donson
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540733,007,257 - 33,015,039 (-)Ensembl
ChiLan1.0NW_00495540733,007,257 - 33,014,600 (-)NCBIChiLan1.0ChiLan1.0
DONSON
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22229,695,344 - 29,706,364 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12124,553,559 - 24,564,583 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02119,944,692 - 19,956,140 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12133,317,147 - 33,328,132 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2133,317,841 - 33,328,132 (-)EnsemblpanPan2panpan1.1
DONSON
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13128,192,338 - 28,209,512 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3128,190,358 - 28,207,190 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03128,397,647 - 28,414,510 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3128,404,214 - 28,414,516 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13128,264,474 - 28,281,296 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03128,284,547 - 28,295,252 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03128,778,176 - 28,794,943 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Donson
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497128,746,902 - 28,755,645 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365008,712,205 - 8,739,953 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365008,712,168 - 8,720,728 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DONSON
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13197,193,658 - 197,203,932 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113197,192,661 - 197,204,243 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213207,004,438 - 207,014,637 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DONSON
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1258,598,341 - 58,627,279 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl258,598,967 - 58,609,316 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660711,100,313 - 1,128,775 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Donson
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474521,798,075 - 21,807,556 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474521,798,712 - 21,807,657 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Donson
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1452,909,339 - 52,932,048 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Donson
95 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:101
Count of miRNA genes:78
Interacting mature miRNAs:91
Transcripts:ENSRNOT00000061304
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)113330600878306008Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11381815448818154Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113330600878306008Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)111080612555806125Rat
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)113532319955805892Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)112995899657754989Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113191546976915469Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)112631803155806125Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111282315257823152Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
631510Spl2Serum phospholipid level QTL 24.1blood phospholipid amount (VT:0006084)serum phospholipid level (CMO:0001171)112755668572556685Rat

Markers in Region
RH127092  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21130,922,750 - 30,922,972 (+)MAPPERmRatBN7.2
mRatBN7.2518,469,521 - 18,469,743 (-)MAPPERmRatBN7.2
mRatBN7.2518,469,521 - 18,469,743 (+)MAPPERmRatBN7.2
mRatBN7.21130,922,750 - 30,922,972 (-)MAPPERmRatBN7.2
Rnor_6.01131,837,353 - 31,837,574NCBIRnor6.0
Rnor_6.0518,442,651 - 18,442,872NCBIRnor6.0
Rnor_5.0523,233,857 - 23,234,078UniSTSRnor5.0
Rnor_5.01135,446,086 - 35,446,307UniSTSRnor5.0
RGSC_v3.4518,796,322 - 18,796,543UniSTSRGSC3.4
RGSC_v3.41131,651,735 - 31,651,956UniSTSRGSC3.4
Celera1130,590,182 - 30,590,403UniSTS
Celera517,788,011 - 17,788,232UniSTS
Cytogenetic Map5q12UniSTS
Cytogenetic Map11q11UniSTS
SON  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2518,469,460 - 18,469,551 (-)MAPPERmRatBN7.2
mRatBN7.21130,922,942 - 30,923,040 (+)MAPPERmRatBN7.2
Rnor_6.01131,837,545 - 31,837,642NCBIRnor6.0
Rnor_5.01135,446,278 - 35,446,375UniSTSRnor5.0
RGSC_v3.41131,651,927 - 31,652,024UniSTSRGSC3.4
Celera1130,590,374 - 30,590,471UniSTS
Cytogenetic Map11q11UniSTS
RH139817  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21130,923,382 - 30,923,593 (+)MAPPERmRatBN7.2
Rnor_6.01131,837,985 - 31,838,195NCBIRnor6.0
Rnor_5.01135,446,718 - 35,446,928UniSTSRnor5.0
RGSC_v3.41131,652,367 - 31,652,577UniSTSRGSC3.4
Celera1130,590,814 - 30,591,024UniSTS
RH 3.4 Map11176.7UniSTS
Cytogenetic Map11q11UniSTS
GDB:335409  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21130,922,942 - 30,923,111 (+)MAPPERmRatBN7.2
mRatBN7.2257,767,720 - 57,767,887 (+)MAPPERmRatBN7.2
Rnor_6.0257,873,107 - 57,873,273NCBIRnor6.0
Rnor_6.01131,837,545 - 31,837,713NCBIRnor6.0
Rnor_5.01135,446,278 - 35,446,446UniSTSRnor5.0
Rnor_5.0279,360,669 - 79,360,835UniSTSRnor5.0
RGSC_v3.4258,282,464 - 58,282,630UniSTSRGSC3.4
RGSC_v3.41131,651,927 - 31,652,095UniSTSRGSC3.4
Celera1130,590,374 - 30,590,542UniSTS
Celera253,380,092 - 53,380,258UniSTS
Cytogenetic Map11q11UniSTS
Cytogenetic Map2q16UniSTS
RH124814  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2518,469,458 - 18,469,554 (-)MAPPERmRatBN7.2
mRatBN7.21130,922,939 - 30,923,035 (+)MAPPERmRatBN7.2
Rnor_6.01131,837,542 - 31,837,637NCBIRnor6.0
Rnor_5.01135,446,275 - 35,446,370UniSTSRnor5.0
RGSC_v3.41131,651,924 - 31,652,019UniSTSRGSC3.4
Celera1130,590,371 - 30,590,466UniSTS
Cytogenetic Map11q11UniSTS
Donson  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21130,926,002 - 30,926,597 (+)MAPPERmRatBN7.2
Rnor_6.01131,840,605 - 31,841,199NCBIRnor6.0
Rnor_5.01135,449,338 - 35,449,932UniSTSRnor5.0
RGSC_v3.41131,654,987 - 31,655,581UniSTSRGSC3.4
Celera1130,593,406 - 30,594,000UniSTS
Cytogenetic Map11q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 355 192 11 144 80 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000061304   ⟹   ENSRNOP00000058017
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1144,405,804 - 44,418,791 (-)Ensembl
mRatBN7.2 Ensembl1130,923,239 - 30,932,889 (-)Ensembl
Rnor_6.0 Ensembl1131,837,839 - 31,847,490 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093955   ⟹   ENSRNOP00000089568
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1144,408,956 - 44,418,791 (-)Ensembl
mRatBN7.2 Ensembl1130,923,245 - 30,932,821 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000172465   ⟹   ENSRNOP00000105624
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1144,409,844 - 44,418,791 (-)Ensembl
RefSeq Acc Id: NM_001008287   ⟹   NP_001008288
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81144,409,195 - 44,418,791 (-)NCBI
mRatBN7.21130,923,235 - 30,932,832 (-)NCBI
Rnor_6.01131,837,837 - 31,847,490 (-)NCBI
Rnor_5.01135,443,360 - 35,456,223 (-)NCBI
RGSC_v3.41131,652,219 - 31,661,872 (-)RGD
Celera1130,590,666 - 30,600,291 (-)RGD
Sequence:
RefSeq Acc Id: NM_001399266   ⟹   NP_001386195
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81144,409,195 - 44,418,791 (-)NCBI
mRatBN7.21130,923,235 - 30,932,832 (-)NCBI
RefSeq Acc Id: NM_001399267   ⟹   NP_001386196
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81144,405,794 - 44,418,791 (-)NCBI
mRatBN7.21130,919,834 - 30,932,832 (-)NCBI
RefSeq Acc Id: XM_017597939   ⟹   XP_017453428
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81144,409,195 - 44,419,099 (-)NCBI
mRatBN7.21130,923,232 - 30,933,150 (-)NCBI
Rnor_6.01131,837,623 - 31,847,751 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017597940   ⟹   XP_017453429
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81144,409,195 - 44,419,099 (-)NCBI
mRatBN7.21130,923,235 - 30,933,150 (-)NCBI
Rnor_6.01131,837,837 - 31,847,751 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063270424   ⟹   XP_063126494
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81144,409,195 - 44,419,099 (-)NCBI
RefSeq Acc Id: XM_063270425   ⟹   XP_063126495
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81144,409,195 - 44,419,099 (-)NCBI
RefSeq Acc Id: XM_063270426   ⟹   XP_063126496
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81144,409,195 - 44,419,099 (-)NCBI
RefSeq Acc Id: NP_001008288   ⟸   NM_001008287
- Peptide Label: isoform 2
- UniProtKB: E9PSU2 (UniProtKB/TrEMBL),   Q5U2V7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453428   ⟸   XM_017597939
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ACX2 (UniProtKB/TrEMBL),   A6JLH3 (UniProtKB/TrEMBL),   Q5U2V7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453429   ⟸   XM_017597940
- Peptide Label: isoform X2
- UniProtKB: Q5U2V7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000058017   ⟸   ENSRNOT00000061304
Ensembl Acc Id: ENSRNOP00000089568   ⟸   ENSRNOT00000093955
RefSeq Acc Id: NP_001386196   ⟸   NM_001399267
- Peptide Label: isoform 1
- UniProtKB: A0A8I6ACX2 (UniProtKB/TrEMBL),   A6JLH3 (UniProtKB/TrEMBL),   Q5U2V7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386195   ⟸   NM_001399266
- Peptide Label: isoform 1
- UniProtKB: A0A8I6ACX2 (UniProtKB/TrEMBL),   A6JLH3 (UniProtKB/TrEMBL),   Q5U2V7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126496   ⟸   XM_063270426
- Peptide Label: isoform X4
- UniProtKB: Q5U2V7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126494   ⟸   XM_063270424
- Peptide Label: isoform X2
- UniProtKB: Q5U2V7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126495   ⟸   XM_063270425
- Peptide Label: isoform X3
- UniProtKB: E9PSU2 (UniProtKB/TrEMBL),   Q5U2V7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000105624   ⟸   ENSRNOT00000172465

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PSU2-F1-model_v2 AlphaFold E9PSU2 1-488 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698061
Promoter ID:EPDNEW_R8586
Type:multiple initiation site
Name:Donson_1
Description:downstream neighbor of SON
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01131,847,405 - 31,847,465EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306823 AgrOrtholog
BioCyc Gene G2FUF-21876 BioCyc
Ensembl Genes ENSRNOG00000002012 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000061304 ENTREZGENE
  ENSRNOT00000061304.5 UniProtKB/TrEMBL
  ENSRNOT00000093955 ENTREZGENE
  ENSRNOT00000093955.2 UniProtKB/TrEMBL
  ENSRNOT00000172465.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7189203 IMAGE-MGC_LOAD
InterPro Donson UniProtKB/TrEMBL
KEGG Report rno:288257 UniProtKB/TrEMBL
MGC_CLONE MGC:94546 IMAGE-MGC_LOAD
NCBI Gene 288257 ENTREZGENE
PANTHER PROTEIN DOWNSTREAM NEIGHBOR OF SON UniProtKB/TrEMBL
  PTHR12972 UniProtKB/TrEMBL
PhenoGen Donson PhenoGen
PRINTS DONSON UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002012 RatGTEx
UniProt A0A8I6ACX2 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LPT5_RAT UniProtKB/TrEMBL
  A6JLH3 ENTREZGENE, UniProtKB/TrEMBL
  E9PSU2 ENTREZGENE, UniProtKB/TrEMBL
  Q5U2V7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-13 Donson  DNA replication fork stabilization factor DONSON  Donson  downstream neighbor of SON  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Donson  downstream neighbor of SON  Donson_predicted  downstream neighbor of SON (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Donson_predicted  downstream neighbor of SON (predicted)      Symbol and Name status set to approved 70820 APPROVED