Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tspyl4 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Tspyl4 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TSPYL4 mRNA | CTD | PMID:36331819 | Tspyl4 | Rat | 1,1-dichloroethene | decreases expression | ISO | Tspyl4 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of TSPYL4 mRNA | CTD | PMID:26682919 | Tspyl4 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Tspyl4 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of TSPYL4 mRNA | CTD | PMID:22206623 | Tspyl4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Tspyl4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TSPYL4 mRNA | CTD | PMID:19770486|PMID:28922406 | Tspyl4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TSPYL4 mRNA | CTD | PMID:33387578 | Tspyl4 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of TSPYL4 mRNA | CTD | PMID:21346803 | Tspyl4 | Rat | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TSPYL4 mRNA | CTD | PMID:23196670 | Tspyl4 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Tspyl4 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of TSPYL4 mRNA | CTD | PMID:39298647 | Tspyl4 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Tspyl4 (Mus musculus) | 6480464 | bisphenol S affects the methylation of TSPYL4 gene | CTD | PMID:31683443 | Tspyl4 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Tspyl4 (Mus musculus) | 6480464 | Fenretinide results in increased expression of TSPYL4 mRNA | CTD | PMID:28973697 | Tspyl4 | Rat | acrylamide | increases expression | ISO | TSPYL4 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of TSPYL4 mRNA | CTD | PMID:32763439 | Tspyl4 | Rat | aflatoxin B1 | decreases expression | ISO | Tspyl4 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of TSPYL4 mRNA | CTD | PMID:19770486 | Tspyl4 | Rat | aflatoxin B1 | increases mutagenesis | EXP | | 6480464 | Aflatoxin B1 results in increased mutagenesis of TSPYL4 gene | CTD | PMID:36908029 | Tspyl4 | Rat | all-trans-retinoic acid | increases expression | ISO | Tspyl4 (Mus musculus) | 6480464 | Tretinoin results in increased expression of TSPYL4 mRNA | CTD | PMID:16604517 | Tspyl4 | Rat | all-trans-retinoic acid | decreases expression | ISO | TSPYL4 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of TSPYL4 mRNA | CTD | PMID:15498508 | Tspyl4 | Rat | arsane | multiple interactions | ISO | TSPYL4 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Tspyl4 | Rat | arsenic atom | multiple interactions | ISO | TSPYL4 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Tspyl4 | Rat | benzo[a]pyrene | decreases expression | ISO | Tspyl4 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of TSPYL4 mRNA | CTD | PMID:19770486 | Tspyl4 | Rat | benzo[a]pyrene | increases methylation | ISO | TSPYL4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TSPYL4 promoter | CTD | PMID:27901495 | Tspyl4 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Tspyl4 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of TSPYL4 mRNA | CTD | PMID:34319233 | Tspyl4 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TSPYL4 mRNA | CTD | PMID:25181051|PMID:34947998 | Tspyl4 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of TSPYL4 gene | CTD | PMID:28505145 | Tspyl4 | Rat | cadmium atom | increases expression | ISO | TSPYL4 (Homo sapiens) | 6480464 | Cadmium results in increased expression of TSPYL4 mRNA | CTD | PMID:24376830 | Tspyl4 | Rat | cadmium atom | multiple interactions | ISO | Tspyl4 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TSPYL4 more ... | CTD | PMID:37236586 | Tspyl4 | Rat | cadmium dichloride | multiple interactions | ISO | Tspyl4 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TSPYL4 more ... | CTD | PMID:37236586 | Tspyl4 | Rat | carbon nanotube | decreases expression | ISO | Tspyl4 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of TSPYL4 mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681 | Tspyl4 | Rat | carbon nanotube | increases expression | ISO | Tspyl4 (Mus musculus) | 6480464 | Nanotubes, Carbon results in increased expression of TSPYL4 mRNA | CTD | PMID:25620056 | Tspyl4 | Rat | choline | multiple interactions | ISO | Tspyl4 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ... | CTD | PMID:20938992 | Tspyl4 | Rat | cisplatin | increases expression | ISO | TSPYL4 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of TSPYL4 mRNA | CTD | PMID:27594783 | Tspyl4 | Rat | cyclosporin A | decreases expression | ISO | TSPYL4 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of TSPYL4 mRNA | CTD | PMID:20106945|PMID:25562108 | Tspyl4 | Rat | dibenz[a,h]anthracene | decreases expression | ISO | Tspyl4 (Mus musculus) | 6480464 | 1,2,5,6-dibenzanthracene results in decreased expression of TSPYL4 mRNA | CTD | PMID:26377693 | Tspyl4 | Rat | Dibutyl phosphate | affects expression | ISO | TSPYL4 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of TSPYL4 mRNA | CTD | PMID:37042841 | Tspyl4 | Rat | dioxygen | multiple interactions | ISO | Tspyl4 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of TSPYL4 mRNA | CTD | PMID:30529165 | Tspyl4 | Rat | doxorubicin | increases expression | ISO | Tspyl4 (Mus musculus) | 6480464 | Doxorubicin results in increased expression of TSPYL4 mRNA | CTD | PMID:39631538 | Tspyl4 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of TSPYL4 mRNA | CTD | PMID:29391264 | Tspyl4 | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of TSPYL4 mRNA | CTD | PMID:30307764 | Tspyl4 | Rat | folic acid | multiple interactions | ISO | Tspyl4 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of TSPYL4 mRNA; [Methionine deficiency co-treated more ... | CTD | PMID:20938992|PMID:22206623 | Tspyl4 | Rat | furan | decreases expression | EXP | | 6480464 | furan results in decreased expression of TSPYL4 mRNA | CTD | PMID:25539665 | Tspyl4 | Rat | genistein | increases methylation | EXP | | 6480464 | Genistein results in increased methylation of TSPYL4 gene | CTD | PMID:28505145 | Tspyl4 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of TSPYL4 mRNA | CTD | PMID:33387578 | Tspyl4 | Rat | hexane | decreases methylation | EXP | | 6480464 | n-hexane results in decreased methylation of TSPYL4 promoter | CTD | PMID:23740543 | Tspyl4 | Rat | isoprenaline | increases expression | ISO | Tspyl4 (Mus musculus) | 6480464 | Isoproterenol results in increased expression of TSPYL4 mRNA | CTD | PMID:20003209 | Tspyl4 | Rat | L-methionine | multiple interactions | ISO | Tspyl4 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ... | CTD | PMID:20938992 | Tspyl4 | Rat | leflunomide | decreases expression | ISO | TSPYL4 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of TSPYL4 mRNA | CTD | PMID:28988120 | Tspyl4 | Rat | leflunomide | decreases expression | EXP | | 6480464 | leflunomide results in decreased expression of TSPYL4 mRNA | CTD | PMID:24136188 | Tspyl4 | Rat | manganese atom | multiple interactions | ISO | TSPYL4 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Tspyl4 | Rat | manganese(0) | multiple interactions | ISO | TSPYL4 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Tspyl4 | Rat | manganese(II) chloride | multiple interactions | ISO | TSPYL4 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Tspyl4 | Rat | N-nitrosodiethylamine | decreases expression | ISO | Tspyl4 (Mus musculus) | 6480464 | Diethylnitrosamine results in decreased expression of TSPYL4 mRNA | CTD | PMID:24535843 | Tspyl4 | Rat | N-nitrosodiethylamine | multiple interactions | ISO | Tspyl4 (Mus musculus) | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of TSPYL4 mRNA | CTD | PMID:24535843 | Tspyl4 | Rat | nickel dichloride | decreases expression | ISO | TSPYL4 (Homo sapiens) | 6480464 | nickel chloride results in decreased expression of TSPYL4 mRNA | CTD | PMID:17312168 | Tspyl4 | Rat | paracetamol | affects expression | ISO | Tspyl4 (Mus musculus) | 6480464 | Acetaminophen affects the expression of TSPYL4 mRNA | CTD | PMID:17562736 | Tspyl4 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of TSPYL4 mRNA | CTD | PMID:33387578 | Tspyl4 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Tspyl4 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TSPYL4 mRNA | CTD | PMID:36331819 | Tspyl4 | Rat | phenobarbital | multiple interactions | ISO | Tspyl4 (Mus musculus) | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of TSPYL4 mRNA; NR1I3 protein affects the more ... | CTD | PMID:19482888|PMID:24535843 | Tspyl4 | Rat | phenobarbital | decreases expression | ISO | Tspyl4 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of TSPYL4 mRNA | CTD | PMID:19270015|PMID:19482888|PMID:23091169 | Tspyl4 | Rat | phenobarbital | affects expression | ISO | TSPYL4 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of TSPYL4 mRNA | CTD | PMID:19159669 | Tspyl4 | Rat | quercetin | decreases expression | ISO | TSPYL4 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of TSPYL4 mRNA | CTD | PMID:21632981 | Tspyl4 | Rat | rotenone | decreases expression | ISO | TSPYL4 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of TSPYL4 mRNA | CTD | PMID:29955902 | Tspyl4 | Rat | sodium arsenite | affects methylation | ISO | TSPYL4 (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of TSPYL4 gene | CTD | PMID:28589171 | Tspyl4 | Rat | sodium arsenite | multiple interactions | ISO | TSPYL4 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Tspyl4 | Rat | sodium arsenite | affects expression | ISO | TSPYL4 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of TSPYL4 mRNA | CTD | PMID:29319823 | Tspyl4 | Rat | tamibarotene | decreases expression | ISO | TSPYL4 (Homo sapiens) | 6480464 | tamibarotene results in decreased expression of TSPYL4 mRNA | CTD | PMID:15498508 | Tspyl4 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of TSPYL4 mRNA | CTD | PMID:23411599|PMID:34492290 | Tspyl4 | Rat | titanium dioxide | decreases methylation | ISO | Tspyl4 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of TSPYL4 gene | CTD | PMID:35295148 | Tspyl4 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of TSPYL4 mRNA | CTD | PMID:33387578 | Tspyl4 | Rat | tris(2-butoxyethyl) phosphate | affects expression | ISO | TSPYL4 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of TSPYL4 mRNA | CTD | PMID:29024780 | Tspyl4 | Rat | urethane | decreases expression | ISO | TSPYL4 (Homo sapiens) | 6480464 | Urethane results in decreased expression of TSPYL4 mRNA | CTD | PMID:28818685 | Tspyl4 | Rat | valdecoxib | decreases expression | EXP | | 6480464 | valdecoxib results in decreased expression of TSPYL4 mRNA | CTD | PMID:24136188 | Tspyl4 | Rat | valproic acid | increases expression | ISO | Tspyl4 (Mus musculus) | 6480464 | Valproic Acid results in increased expression of TSPYL4 mRNA | CTD | PMID:20546886|PMID:21427059 | Tspyl4 | Rat | valproic acid | increases expression | ISO | TSPYL4 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TSPYL4 mRNA | CTD | PMID:29154799 | Tspyl4 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of TSPYL4 mRNA | CTD | PMID:23034163 | | 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