Rnf146 (ring finger protein 146) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Rnf146 (ring finger protein 146) Rattus norvegicus
Analyze
Symbol: Rnf146
Name: ring finger protein 146
RGD ID: 1306482
Description: Enables enzyme binding activity. Involved in several processes, including cellular response to glucose stimulus; cellular response to hydrogen peroxide; and negative regulation of cellular response to oxidative stress. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in cytoplasm and nucleus. Orthologous to human RNF146 (ring finger protein 146); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase RNF146; iduna; LOC308051; RING-type E3 ubiquitin transferase RNF146
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8130,286,680 - 30,304,367 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl130,287,511 - 30,304,361 (+)EnsemblGRCr8
mRatBN7.2128,458,864 - 28,475,758 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl128,458,887 - 28,475,923 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx128,260,504 - 28,271,097 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0134,260,355 - 34,270,948 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0128,461,120 - 28,471,713 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd129,858,220 - 29,868,813 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive129,182,953 - 29,193,546 (+)NCBILyon_Normotensive
Lyon_Hypertensive130,349,133 - 30,359,726 (+)NCBILyon_Hypertensive
F344_StmMcwi128,654,055 - 28,664,648 (+)NCBIF344_StmMcwi
Rnor_6.0130,856,923 - 30,873,814 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl130,863,217 - 30,873,808 (+)Ensemblrn6Rnor6.0
Rnor_5.0132,290,907 - 32,307,789 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4129,255,138 - 29,265,731 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera127,132,709 - 27,143,302 (+)NCBICelera
RGSC_v3.1129,258,082 - 29,268,670 (+)NCBI
Cytogenetic Map1p11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
cytosol  (IEA,ISO,ISS)
nucleus  (IBA,IEA)
plasma membrane  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation. Barkauskaite E, etal., Mol Cell. 2015 Jun 18;58(6):935-46. doi: 10.1016/j.molcel.2015.05.007.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Salvage of nicotinamide adenine dinucleotide plays a critical role in the bioenergetic recovery of post-hypoxic cardiomyocytes. Gero D and Szabo C, Br J Pharmacol. 2015 Oct;172(20):4817-32. doi: 10.1111/bph.13252. Epub 2015 Oct 14.
4. Modulation of poly(ADP-ribose) polymerase-1 (PARP-1)-mediated oxidative cell injury by ring finger protein 146 (RNF146) in cardiac myocytes. Gerö D, etal., Mol Med. 2014 Jul 31;20:313-28. doi: 10.2119/molmed.2014.00102.
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Downregulation of Iduna is associated with AIF nuclear translocation in neonatal brain after hypoxia-ischemia. Yang X, etal., Neuroscience. 2017 Mar 27;346:74-80. doi: 10.1016/j.neuroscience.2017.01.010. Epub 2017 Jan 17.
Additional References at PubMed
PMID:8889548   PMID:12477932   PMID:15489334   PMID:15813938   PMID:21478859   PMID:32326811  


Genomics

Comparative Map Data
Rnf146
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8130,286,680 - 30,304,367 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl130,287,511 - 30,304,361 (+)EnsemblGRCr8
mRatBN7.2128,458,864 - 28,475,758 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl128,458,887 - 28,475,923 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx128,260,504 - 28,271,097 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0134,260,355 - 34,270,948 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0128,461,120 - 28,471,713 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd129,858,220 - 29,868,813 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive129,182,953 - 29,193,546 (+)NCBILyon_Normotensive
Lyon_Hypertensive130,349,133 - 30,359,726 (+)NCBILyon_Hypertensive
F344_StmMcwi128,654,055 - 28,664,648 (+)NCBIF344_StmMcwi
Rnor_6.0130,856,923 - 30,873,814 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl130,863,217 - 30,873,808 (+)Ensemblrn6Rnor6.0
Rnor_5.0132,290,907 - 32,307,789 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4129,255,138 - 29,265,731 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera127,132,709 - 27,143,302 (+)NCBICelera
RGSC_v3.1129,258,082 - 29,268,670 (+)NCBI
Cytogenetic Map1p11NCBI
RNF146
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386127,266,682 - 127,288,562 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6127,266,582 - 127,288,567 (+)Ensemblhg38GRCh38
GRCh376127,587,827 - 127,609,707 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366127,629,713 - 127,651,202 (+)NCBIBuild 36Build 36hg18NCBI36
Build 346127,629,712 - 127,651,198NCBI
Celera6128,330,302 - 128,351,791 (+)NCBICelera
Cytogenetic Map6q22.33NCBI
HuRef6125,164,466 - 125,186,349 (+)NCBIHuRef
CHM1_16127,852,150 - 127,874,042 (+)NCBICHM1_1
T2T-CHM13v2.06128,455,637 - 128,477,520 (+)NCBIT2T-CHM13v2.0
Rnf146
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391029,220,172 - 29,238,438 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1029,220,172 - 29,238,438 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381029,344,176 - 29,362,442 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1029,344,176 - 29,362,442 (-)Ensemblmm10GRCm38
MGSCv371029,063,982 - 29,082,248 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361029,035,587 - 29,051,858 (-)NCBIMGSCv36mm8
Celera1030,276,585 - 30,294,697 (-)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1016.6NCBI
Rnf146
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554368,312,096 - 8,331,648 (+)NCBIChiLan1.0ChiLan1.0
RNF146
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25147,263,264 - 147,284,796 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16145,172,033 - 145,193,592 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06125,057,312 - 125,079,096 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16129,170,440 - 129,192,602 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6129,190,562 - 129,191,733 (+)EnsemblpanPan2panpan1.1
RNF146
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1165,988,600 - 66,010,873 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl165,988,656 - 66,010,881 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha166,794,457 - 66,816,710 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0166,191,606 - 66,213,917 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl166,191,010 - 66,213,917 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1166,121,749 - 66,143,998 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0165,906,358 - 65,928,595 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0166,548,694 - 66,570,938 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rnf146
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946116,001,734 - 116,023,924 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366392,393,150 - 2,417,982 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366392,394,566 - 2,417,452 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF146
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl135,909,575 - 35,926,968 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1135,909,789 - 35,927,265 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2139,594,042 - 39,612,617 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RNF146
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11346,441,069 - 46,462,533 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1346,441,741 - 46,442,823 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604018,718,979 - 18,740,720 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf146
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247531,671,614 - 1,706,793 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Rnf146
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12203,414,618 - 203,432,684 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rnf146
64 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:375
Count of miRNA genes:222
Interacting mature miRNAs:260
Transcripts:ENSRNOT00000015421
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1529322934184556Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1774611852746118Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1774612152746121Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12940927974409279Rat
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)1143965634Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)11037949255379492Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1694102251941022Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1529322934184556Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)1690935351909353Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11731537851816258Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)1690935351909353Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)1690935351909353Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11282049457820494Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)1134184556Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)12065642065656420Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12050832665508326Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)11168446456684464Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1529322934184556Rat

Markers in Region
BF394734  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0132,299,301 - 32,299,475NCBIRnor5.0
RGSC_v3.4129,257,248 - 29,257,418UniSTSRGSC3.4
Celera127,134,819 - 27,134,989UniSTS
RH 3.4 Map1312.58UniSTS
Cytogenetic Map1p11UniSTS
RH127705  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2128,475,492 - 28,475,678 (+)MAPPERmRatBN7.2
Rnor_6.0130,873,549 - 30,873,734NCBIRnor6.0
Rnor_5.0132,307,524 - 32,307,709UniSTSRnor5.0
RGSC_v3.4129,265,466 - 29,265,651UniSTSRGSC3.4
Celera127,143,037 - 27,143,222UniSTS
Cytogenetic Map1p11UniSTS
BF389128  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2128,464,987 - 28,465,143 (+)MAPPERmRatBN7.2
Rnor_6.0130,863,040 - 30,863,195NCBIRnor6.0
Rnor_5.0132,297,015 - 32,297,170UniSTSRnor5.0
RGSC_v3.4129,254,961 - 29,255,116UniSTSRGSC3.4
Celera127,132,532 - 27,132,687UniSTS
RH 3.4 Map1317.4UniSTS
Cytogenetic Map1p11UniSTS
RH139137  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2128,470,809 - 28,470,932 (+)MAPPERmRatBN7.2
Rnor_6.0130,868,866 - 30,868,988NCBIRnor6.0
Rnor_5.0132,302,841 - 32,302,963UniSTSRnor5.0
RGSC_v3.4129,260,783 - 29,260,905UniSTSRGSC3.4
Celera127,138,354 - 27,138,476UniSTS
RH 3.4 Map1314.2UniSTS
Cytogenetic Map1p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000015421   ⟹   ENSRNOP00000015421
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl130,287,511 - 30,304,361 (+)Ensembl
mRatBN7.2 Ensembl128,458,887 - 28,475,748 (+)Ensembl
Rnor_6.0 Ensembl130,863,217 - 30,873,808 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110925   ⟹   ENSRNOP00000094151
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl128,458,890 - 28,475,923 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119984   ⟹   ENSRNOP00000081042
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl130,293,774 - 30,304,359 (+)Ensembl
mRatBN7.2 Ensembl128,458,890 - 28,475,923 (+)Ensembl
RefSeq Acc Id: NM_001012060   ⟹   NP_001012060
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8130,293,774 - 30,304,367 (+)NCBI
mRatBN7.2128,465,165 - 28,475,758 (+)NCBI
Dahl_SR_JrHsd129,858,220 - 29,868,813 (+)NCBI
Lyon_Normotensive129,182,953 - 29,193,546 (+)NCBI
Lyon_Hypertensive130,349,133 - 30,359,726 (+)NCBI
F344_StmMcwi128,654,055 - 28,664,648 (+)NCBI
Rnor_6.0130,863,217 - 30,873,814 (+)NCBI
Rnor_5.0132,290,907 - 32,307,789 (+)NCBI
RGSC_v3.4129,255,138 - 29,265,731 (+)RGD
Celera127,132,709 - 27,143,302 (+)RGD
Sequence:
RefSeq Acc Id: XM_006227744   ⟹   XP_006227806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8130,286,680 - 30,304,364 (+)NCBI
mRatBN7.2128,458,864 - 28,475,755 (+)NCBI
Rnor_6.0130,856,923 - 30,873,811 (+)NCBI
Rnor_5.0132,290,907 - 32,307,789 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006227745   ⟹   XP_006227807
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8130,287,497 - 30,304,364 (+)NCBI
mRatBN7.2128,458,884 - 28,475,755 (+)NCBI
Rnor_6.0130,856,932 - 30,873,811 (+)NCBI
Rnor_5.0132,290,907 - 32,307,789 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001012060 (Get FASTA)   NCBI Sequence Viewer  
  XP_006227806 (Get FASTA)   NCBI Sequence Viewer  
  XP_006227807 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH83675 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000015421
  ENSRNOP00000081042.1
  ENSRNOP00000094151.1
GenBank Protein Q5XIK5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001012060   ⟸   NM_001012060
- UniProtKB: Q5XIK5 (UniProtKB/Swiss-Prot),   A0A140TAB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006227806   ⟸   XM_006227744
- Peptide Label: isoform X1
- UniProtKB: Q5XIK5 (UniProtKB/Swiss-Prot),   A0A140TAB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006227807   ⟸   XM_006227745
- Peptide Label: isoform X1
- UniProtKB: Q5XIK5 (UniProtKB/Swiss-Prot),   A0A140TAB2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000015421   ⟸   ENSRNOT00000015421
Ensembl Acc Id: ENSRNOP00000081042   ⟸   ENSRNOT00000119984
Ensembl Acc Id: ENSRNOP00000094151   ⟸   ENSRNOT00000110925
Protein Domains
RING-type   WWE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XIK5-F1-model_v2 AlphaFold Q5XIK5 1-352 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689548
Promoter ID:EPDNEW_R72
Type:single initiation site
Name:Rnf146_1
Description:ring finger protein 146
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0130,863,207 - 30,863,267EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306482 AgrOrtholog
BioCyc Gene G2FUF-61961 BioCyc
Ensembl Genes ENSRNOG00000011588 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000015421 ENTREZGENE
  ENSRNOT00000110925.1 UniProtKB/Swiss-Prot
  ENSRNOT00000119984.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot
  3.30.720.50 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7135728 IMAGE-MGC_LOAD
InterPro RING-HC_RNF146 UniProtKB/Swiss-Prot
  RNF146 UniProtKB/Swiss-Prot
  WWE-dom UniProtKB/Swiss-Prot
  WWE-dom_subgr UniProtKB/Swiss-Prot
  WWE_dom_sf UniProtKB/Swiss-Prot
  Znf_RING UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
  Znf_RING_CS UniProtKB/Swiss-Prot
KEGG Report rno:308051 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94520 IMAGE-MGC_LOAD
NCBI Gene 308051 ENTREZGENE
PANTHER PTHR13417:SF2 UniProtKB/Swiss-Prot
  UNCHARACTERIZED UniProtKB/Swiss-Prot
Pfam WWE UniProtKB/Swiss-Prot
  zf-C3HC4_3 UniProtKB/Swiss-Prot
PhenoGen Rnf146 PhenoGen
PROSITE WWE UniProtKB/Swiss-Prot
  ZF_RING_1 UniProtKB/Swiss-Prot
  ZF_RING_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000011588 RatGTEx
SMART RING UniProtKB/Swiss-Prot
  WWE UniProtKB/Swiss-Prot
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot
  SSF117839 UniProtKB/Swiss-Prot
UniProt A0A140TAB2 ENTREZGENE, UniProtKB/TrEMBL
  Q5XIK5 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Rnf146  ring finger protein 146  Rnf146_predicted  ring finger protein 146 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Rnf146_predicted  ring finger protein 146 (predicted)      Symbol and Name status set to approved 70820 APPROVED