Fmn1 (formin 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Fmn1 (formin 1) Rattus norvegicus
Analyze
Symbol: Fmn1
Name: formin 1
RGD ID: 1306349
Description: Predicted to enable SH3 domain binding activity. Predicted to be involved in actin cytoskeleton organization. Predicted to act upstream of or within several processes, including limb morphogenesis; positive regulation of cellular component organization; and ureteric bud invasion. Predicted to be located in cytoplasm. Predicted to be active in endoplasmic reticulum membrane and nucleus. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human FMN1 (formin 1); PARTICIPATES IN E-cadherin signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; atrazine; azoxystrobin.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: formin-1; LOC102551877; LOC296053; LOC296512; LOC687921; mRNA turnover protein 4 homolog; RGD1306349; RGD1310100; similar to formin; similar to formin, isoform IV; similar to Formin-1 isoform IV (Limb deformity protein)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83120,555,445 - 120,939,978 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3120,555,431 - 120,933,124 (+)EnsemblGRCr8
mRatBN7.23100,101,103 - 100,485,652 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3100,134,549 - 100,479,220 (+)EnsemblmRatBN7.2
Rnor_6.03104,783,093 - 105,170,761 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3104,816,987 - 105,086,436 (+)Ensemblrn6Rnor6.0
Rnor_5.03111,402,075 - 111,748,675 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4399,298,261 - 99,564,034 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera399,081,027 - 99,451,618 (+)NCBICelera
RGSC_v3.1399,093,741 - 99,460,041 (+)NCBI
Cytogenetic Map3q35NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
azoxystrobin  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chloroquine  (EXP)
chlorpyrifos  (EXP,ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
Dibutyl phosphate  (ISO)
dichloroacetic acid  (ISO)
entinostat  (ISO)
folic acid  (ISO)
FR900359  (ISO)
glyphosate  (EXP)
imidacloprid  (EXP)
indole-3-methanol  (EXP)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monoethyl phthalate  (ISO)
N-nitrosodiethylamine  (EXP)
niclosamide  (ISO)
ozone  (ISO)
phenobarbital  (ISO)
picene  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
succimer  (ISO)
sunitinib  (ISO)
thiabendazole  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trametinib  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
valproic acid  (EXP,ISO)
vorinostat  (ISO)
xylitol  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. An association study revealed substantial effects of dominance, epistasis and substance dependence co-morbidity on alcohol dependence symptom count. Chen G, etal., Addict Biol. 2017 Nov;22(6):1475-1485. doi: 10.1111/adb.12402. Epub 2016 May 5.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2997621   PMID:7517224   PMID:8438166   PMID:8798555   PMID:9234242   PMID:14647292   PMID:16480715   PMID:17554679   PMID:18560567   PMID:21818269   PMID:22427691   PMID:25901598  
PMID:27145014  


Genomics

Comparative Map Data
Fmn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83120,555,445 - 120,939,978 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3120,555,431 - 120,933,124 (+)EnsemblGRCr8
mRatBN7.23100,101,103 - 100,485,652 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3100,134,549 - 100,479,220 (+)EnsemblmRatBN7.2
Rnor_6.03104,783,093 - 105,170,761 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3104,816,987 - 105,086,436 (+)Ensemblrn6Rnor6.0
Rnor_5.03111,402,075 - 111,748,675 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4399,298,261 - 99,564,034 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera399,081,027 - 99,451,618 (+)NCBICelera
RGSC_v3.1399,093,741 - 99,460,041 (+)NCBI
Cytogenetic Map3q35NCBI
FMN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381532,765,544 - 33,194,714 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1532,765,544 - 33,194,714 (-)Ensemblhg38GRCh38
GRCh371533,057,745 - 33,486,915 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361530,853,637 - 31,147,377 (-)NCBIBuild 36Build 36hg18NCBI36
Celera159,859,583 - 10,161,753 (-)NCBICelera
Cytogenetic Map15q13.3NCBI
HuRef159,919,586 - 10,348,532 (-)NCBIHuRef
CHM1_11533,175,802 - 33,604,909 (-)NCBICHM1_1
T2T-CHM13v2.01530,562,099 - 30,991,198 (-)NCBIT2T-CHM13v2.0
Fmn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392113,158,029 - 113,547,113 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2113,158,081 - 113,547,112 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382113,327,664 - 113,716,768 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2113,327,736 - 113,716,767 (+)Ensemblmm10GRCm38
MGSCv372113,167,893 - 113,556,924 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362113,128,621 - 113,510,694 (+)NCBIMGSCv36mm8
Celera2114,475,948 - 114,857,068 (+)NCBICelera
Cytogenetic Map2E4NCBI
cM Map257.3NCBI
Fmn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554161,365,765 - 1,774,027 (+)Ensembl
ChiLan1.0NW_0049554161,365,797 - 1,774,025 (+)NCBIChiLan1.0ChiLan1.0
FMN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21621,540,304 - 21,971,453 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11526,261,987 - 26,693,020 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01511,271,794 - 11,698,539 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11530,105,345 - 30,534,051 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1530,114,113 - 30,495,909 (-)EnsemblpanPan2panpan1.1
FMN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1301,782,726 - 2,215,449 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl301,815,512 - 2,184,909 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha301,831,514 - 2,265,024 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0301,887,585 - 2,328,019 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl301,886,557 - 2,306,834 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1301,830,799 - 2,264,355 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0301,930,068 - 2,363,602 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0302,058,309 - 2,491,979 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fmn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864080,312,906 - 80,727,325 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366731,432,927 - 1,719,966 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366731,424,513 - 1,838,277 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FMN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1136,704,090 - 137,163,537 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11136,696,353 - 137,163,532 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21153,217,402 - 153,269,191 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FMN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12649,700,309 - 50,117,799 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2649,734,553 - 49,996,405 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604890,768,699 - 91,187,937 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fmn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248041,155,071 - 1,558,145 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248041,124,322 - 1,558,781 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Fmn1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1591,562,877 - 91,925,937 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fmn1
2477 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:76
Count of miRNA genes:69
Interacting mature miRNAs:74
Transcripts:ENSRNOT00000041910, ENSRNOT00000042103
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)396509147141509147Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)3116582412136118980Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)385062224136118980Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)385062224136118980Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)3104545086149545086Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)381425008141509147Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)393829559138829559Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)3112250810157250810Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)3101255536134750886Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)396509147141509147Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)3117537367162537367Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)381541464126563126Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)390755164141509147Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)342158111124558371Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1582252Sual1Serum uric acid level QTL 13.40.0123blood uric acid amount (VT:0010302)blood uric acid level (CMO:0000501)3116582412122654872Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)342158111124558371Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)3116188400161188400Rat

Markers in Region
stSG622307  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera399,437,785 - 99,438,735UniSTS
Cytogenetic Map3q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 85 84 53 79 53 6 337 179 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000041910   ⟹   ENSRNOP00000050868
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3120,672,481 - 120,858,339 (+)Ensembl
mRatBN7.2 Ensembl3100,205,121 - 100,404,210 (+)Ensembl
Rnor_6.0 Ensembl3104,899,682 - 105,086,436 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000042103   ⟹   ENSRNOP00000042712
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3120,555,440 - 120,933,124 (+)Ensembl
mRatBN7.2 Ensembl3100,134,549 - 100,479,220 (+)Ensembl
Rnor_6.0 Ensembl3104,816,987 - 105,086,436 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000044625   ⟹   ENSRNOP00000047506
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3120,556,063 - 120,933,124 (+)Ensembl
mRatBN7.2 Ensembl3100,134,821 - 100,479,220 (+)Ensembl
Rnor_6.0 Ensembl3104,816,987 - 105,086,436 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098989   ⟹   ENSRNOP00000094328
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3120,672,481 - 120,933,124 (+)Ensembl
mRatBN7.2 Ensembl3100,205,121 - 100,479,220 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114830   ⟹   ENSRNOP00000091414
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3120,638,181 - 120,933,124 (+)Ensembl
mRatBN7.2 Ensembl3100,183,836 - 100,479,220 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000148035   ⟹   ENSRNOP00000109321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3120,555,440 - 120,933,124 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000154397   ⟹   ENSRNOP00000108711
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3120,555,431 - 120,933,124 (+)Ensembl
RefSeq Acc Id: XM_039106466   ⟹   XP_038962394
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,555,447 - 120,939,978 (+)NCBI
mRatBN7.23100,101,103 - 100,485,652 (+)NCBI
RefSeq Acc Id: XM_039106467   ⟹   XP_038962395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,555,445 - 120,939,978 (+)NCBI
mRatBN7.23100,101,109 - 100,485,652 (+)NCBI
RefSeq Acc Id: XM_039106468   ⟹   XP_038962396
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,555,576 - 120,939,978 (+)NCBI
mRatBN7.23100,101,382 - 100,485,652 (+)NCBI
RefSeq Acc Id: XM_039106470   ⟹   XP_038962398
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,671,429 - 120,939,978 (+)NCBI
mRatBN7.23100,217,053 - 100,485,652 (+)NCBI
RefSeq Acc Id: XM_039106472   ⟹   XP_038962400
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,647,575 - 120,939,978 (+)NCBI
mRatBN7.23100,196,233 - 100,485,652 (+)NCBI
RefSeq Acc Id: XM_039106474   ⟹   XP_038962402
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,721,410 - 120,939,978 (+)NCBI
mRatBN7.23100,267,076 - 100,485,652 (+)NCBI
RefSeq Acc Id: XM_063285289   ⟹   XP_063141359
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,555,445 - 120,939,978 (+)NCBI
RefSeq Acc Id: XM_063285290   ⟹   XP_063141360
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,555,445 - 120,939,978 (+)NCBI
RefSeq Acc Id: XM_063285291   ⟹   XP_063141361
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,555,476 - 120,939,978 (+)NCBI
RefSeq Acc Id: XM_063285292   ⟹   XP_063141362
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,555,445 - 120,672,613 (+)NCBI
RefSeq Acc Id: XM_063285293   ⟹   XP_063141363
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,555,445 - 120,645,466 (+)NCBI
Ensembl Acc Id: ENSRNOP00000050868   ⟸   ENSRNOT00000041910
Ensembl Acc Id: ENSRNOP00000047506   ⟸   ENSRNOT00000044625
Ensembl Acc Id: ENSRNOP00000042712   ⟸   ENSRNOT00000042103
RefSeq Acc Id: XP_038962394   ⟸   XM_039106466
- Peptide Label: isoform X1
- UniProtKB: D4A4Y9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962395   ⟸   XM_039106467
- Peptide Label: isoform X1
- UniProtKB: D4A4Y9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962396   ⟸   XM_039106468
- Peptide Label: isoform X1
- UniProtKB: D4A4Y9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962400   ⟸   XM_039106472
- Peptide Label: isoform X5
- UniProtKB: A0A8I6GJL6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962398   ⟸   XM_039106470
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AHH7 (UniProtKB/TrEMBL),   D3ZBI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962402   ⟸   XM_039106474
- Peptide Label: isoform X8
Ensembl Acc Id: ENSRNOP00000091414   ⟸   ENSRNOT00000114830
Ensembl Acc Id: ENSRNOP00000094328   ⟸   ENSRNOT00000098989
RefSeq Acc Id: XP_063141360   ⟸   XM_063285290
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063141359   ⟸   XM_063285289
- Peptide Label: isoform X2
- UniProtKB: D4A7C2 (UniProtKB/TrEMBL),   D4A4Y9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141362   ⟸   XM_063285292
- Peptide Label: isoform X6
- UniProtKB: A6HP62 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141363   ⟸   XM_063285293
- Peptide Label: isoform X7
- UniProtKB: A6HP62 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141361   ⟸   XM_063285291
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000108711   ⟸   ENSRNOT00000154397
Ensembl Acc Id: ENSRNOP00000109321   ⟸   ENSRNOT00000148035
Protein Domains
FH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A4Y9-F1-model_v2 AlphaFold D4A4Y9 1-1366 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306349 AgrOrtholog
BioCyc Gene G2FUF-48365 BioCyc
Ensembl Genes ENSRNOG00000031760 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000041910.7 UniProtKB/TrEMBL
  ENSRNOT00000042103 ENTREZGENE
  ENSRNOT00000042103.6 UniProtKB/TrEMBL
  ENSRNOT00000044625 ENTREZGENE
  ENSRNOT00000044625.7 UniProtKB/TrEMBL
  ENSRNOT00000098989 ENTREZGENE
  ENSRNOT00000098989.2 UniProtKB/TrEMBL
  ENSRNOT00000114830 ENTREZGENE
  ENSRNOT00000114830.2 UniProtKB/TrEMBL
  ENSRNOT00000148035.1 UniProtKB/TrEMBL
  ENSRNOT00000154397.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.2220 UniProtKB/TrEMBL
InterPro FH2_Formin UniProtKB/TrEMBL
  FH2_Formin_sf UniProtKB/TrEMBL
  Formin_Cappuccino_subfam UniProtKB/TrEMBL
NCBI Gene 296512 ENTREZGENE
PANTHER FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I UniProtKB/TrEMBL
  FORMIN-G UniProtKB/TrEMBL
Pfam FH2 UniProtKB/TrEMBL
PhenoGen Fmn1 PhenoGen
PRINTS FORMIN UniProtKB/TrEMBL
PROSITE FH2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000031760 RatGTEx
SMART FH2 UniProtKB/TrEMBL
Superfamily-SCOP Formin homology 2 domain (FH2 domain) UniProtKB/TrEMBL
UniProt A0A8I6AHH7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJL6 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LDA8_RAT UniProtKB/TrEMBL
  A0ABK0M3Y9_RAT UniProtKB/TrEMBL
  A6HP62 ENTREZGENE, UniProtKB/TrEMBL
  D3ZBI5 ENTREZGENE, UniProtKB/TrEMBL
  D4A4Y9 ENTREZGENE, UniProtKB/TrEMBL
  D4A7C2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Fmn1  formin 1  LOC102551877  mRNA turnover protein 4 homolog  Data merged from RGD:7679496 737654 PROVISIONAL
2013-12-18 LOC102551877  mRNA turnover protein 4 homolog      Symbol and Name status set to provisional 70820 PROVISIONAL
2009-06-16 Fmn1  formin 1  RGD1306349  similar to formin   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-06-15 RGD1306349  similar to formin   LOC687921  similar to Formin-1 isoform IV (Limb deformity protein)  Data merged from RGD:1594927 737654 PROVISIONAL
2009-06-15 RGD1306349  similar to formin   RGD1310100  similar to formin, isoform IV   Data merged from RGD:1310100 1643240 APPROVED
2008-04-30 RGD1306349  similar to formin   RGD1306349_predicted  similar to formin (predicted)  'predicted' is removed 2292626 APPROVED
2008-04-30 RGD1310100  similar to formin, isoform IV   RGD1310100_predicted  similar to formin, isoform IV (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-20 LOC687921  similar to Formin-1 isoform IV (Limb deformity protein)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 RGD1306349_predicted  similar to formin (predicted)  LOC296512_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-20 RGD1310100_predicted  similar to formin, isoform IV (predicted)  LOC296053_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC296512_predicted  similar to formin (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 LOC296053_predicted  similar to formin, isoform IV (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL