Ubxn7 (UBX domain protein 7) - Rat Genome Database

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Gene: Ubxn7 (UBX domain protein 7) Rattus norvegicus
Analyze
Symbol: Ubxn7 (Ensembl: AABR07034438.1)
Name: UBX domain protein 7
RGD ID: 1306346
Description: Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity; ubiquitin binding activity; and ubiquitin protein ligase binding activity. Predicted to be located in nucleoplasm. Predicted to be part of VCP-NPL4-UFD1 AAA ATPase complex. Orthologous to human UBXN7 (UBX domain protein 7); INTERACTS WITH 17alpha-ethynylestradiol; 3-chloropropane-1,2-diol; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC303878; RGD1306346; similar to KIAA0794 protein; UBX domain containing 7; UBX domain-containing protein 7; Ubxd7
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81181,903,235 - 81,920,998 (-)NCBIGRCr8GRCr8GRCr8
GRCr81181,932,944 - 81,965,142 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1181,903,996 - 81,965,142 (-)EnsemblGRCr8
mRatBN7.21168,427,896 - 68,460,100 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1177,264,949 - 77,297,147 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01169,929,535 - 69,961,720 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01168,954,065 - 68,986,274 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01171,662,786 - 71,695,031 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01174,746,898 - 74,779,143 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41170,244,797 - 70,278,154 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1167,860,074 - 67,892,263 (-)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:18775313  


Genomics

Comparative Map Data
Ubxn7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81181,903,235 - 81,920,998 (-)NCBIGRCr8GRCr8GRCr8
GRCr81181,932,944 - 81,965,142 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1181,903,996 - 81,965,142 (-)EnsemblGRCr8
mRatBN7.21168,427,896 - 68,460,100 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1177,264,949 - 77,297,147 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01169,929,535 - 69,961,720 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01168,954,065 - 68,986,274 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01171,662,786 - 71,695,031 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01174,746,898 - 74,779,143 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41170,244,797 - 70,278,154 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1167,860,074 - 67,892,263 (-)NCBICelera
Cytogenetic Map11q22NCBI
UBXN7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383196,347,662 - 196,432,427 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3196,347,659 - 196,432,430 (-)Ensemblhg38GRCh38
GRCh373196,074,533 - 196,159,298 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363197,564,758 - 197,643,742 (-)NCBIBuild 36Build 36hg18NCBI36
Celera3194,660,553 - 194,739,639 (-)NCBICelera
Cytogenetic Map3q29NCBI
HuRef3193,377,621 - 193,456,809 (-)NCBIHuRef
CHM1_13196,051,176 - 196,130,805 (-)NCBICHM1_1
T2T-CHM13v2.03199,066,970 - 199,151,765 (-)NCBIT2T-CHM13v2.0
Ubxn7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391632,151,023 - 32,212,568 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1632,151,075 - 32,212,565 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381632,332,200 - 32,393,747 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1632,332,257 - 32,393,747 (+)Ensemblmm10GRCm38
MGSCv371632,332,338 - 32,393,833 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361632,250,293 - 32,307,639 (+)NCBIMGSCv36mm8
Celera1632,816,736 - 32,878,232 (+)NCBICelera
Cytogenetic Map16B2- B3NCBI
cM Map1622.58NCBI
Ubxn7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542012,555,144 - 12,595,155 (-)Ensembl
ChiLan1.0NW_00495542012,555,144 - 12,594,452 (-)NCBIChiLan1.0ChiLan1.0
UBXN7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22194,219,875 - 194,304,473 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13194,224,593 - 194,310,043 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03193,699,924 - 193,778,452 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13203,643,418 - 203,719,245 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3203,643,126 - 203,719,317 (-)EnsemblpanPan2panpan1.1
UBXN7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13329,454,233 - 29,511,753 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3329,457,337 - 29,511,703 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3329,476,027 - 29,536,200 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03329,690,262 - 29,753,198 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.13329,472,307 - 29,532,471 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03329,526,886 - 29,587,293 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03330,149,366 - 30,209,851 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ubxn7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602124,846,740 - 124,901,853 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936784987,411 - 1,039,050 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936784987,411 - 1,038,483 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBXN7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.113133,689,783 - 133,753,605 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
UBXN7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11590,770,294 - 90,844,744 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1590,771,109 - 90,841,953 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604164,576,121 - 64,654,972 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ubxn7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473061,507,095 - 61,571,931 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473061,505,225 - 61,571,945 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ubxn7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1417,141,769 - 17,202,489 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ubxn7
133 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:290
Count of miRNA genes:192
Interacting mature miRNAs:218
Transcripts:ENSRNOT00000029842, ENSRNOT00000073550
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)117330848796070872Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117961851999753367Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)115893182292356038Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)115775483796071021Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)116859932196497754Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 1 18 51 67 134 95 11 50 32 32 17 17

Sequence


RefSeq Acc Id: NM_001107086   ⟹   NP_001100556
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,932,944 - 81,965,142 (-)NCBI
mRatBN7.21168,427,896 - 68,460,100 (-)NCBI
Rnor_6.01171,662,786 - 71,695,031 (-)NCBI
Rnor_5.01174,746,898 - 74,779,143 (-)NCBI
RGSC_v3.41170,244,797 - 70,278,154 (-)RGD
Celera1167,860,074 - 67,892,263 (-)RGD
Sequence:
RefSeq Acc Id: XM_063270938   ⟹   XP_063127008
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,903,235 - 81,920,998 (-)NCBI
RefSeq Acc Id: NP_001100556   ⟸   NM_001107086
- Sequence:
RefSeq Acc Id: XP_063127008   ⟸   XM_063270938
Protein Domains
UBA-like   UBX

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306346 AgrOrtholog
BioCyc Gene G2FUF-21091 BioCyc
Ensembl Genes ENSRNOG00000046969 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000029842.7 UniProtKB/TrEMBL
  ENSRNOT00000073550.4 UniProtKB/TrEMBL
  ENSRNOT00000091575.3 UniProtKB/TrEMBL
Gene3D-CATH DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
  Glutaredoxin UniProtKB/TrEMBL
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/TrEMBL
InterPro Thioredoxin-like_sf UniProtKB/TrEMBL
  UAS UniProtKB/TrEMBL
  UBA-like_sf UniProtKB/TrEMBL
  UBA_8 UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
  UBX_7/2 UniProtKB/TrEMBL
  UBX_dom UniProtKB/TrEMBL
  UBX_domain-protein UniProtKB/TrEMBL
KEGG Report rno:303878 UniProtKB/TrEMBL
NCBI Gene 303878 ENTREZGENE
PANTHER FAS-ASSOCIATED PROTEIN UniProtKB/TrEMBL
  UBX DOMAIN-CONTAINING PROTEIN 7 UniProtKB/TrEMBL
Pfam Thioredoxin_7 UniProtKB/TrEMBL
  UBA_8 UniProtKB/TrEMBL
  UBX UniProtKB/TrEMBL
PhenoGen Ubxn7 PhenoGen
PIRSF UCP037991_UBX7/2 UniProtKB/TrEMBL
PROSITE UBX UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046969 RatGTEx
SMART UAS UniProtKB/TrEMBL
  UBX UniProtKB/TrEMBL
Superfamily-SCOP Thioredoxin-like UniProtKB/TrEMBL
  UBA-like UniProtKB/TrEMBL
  Ubiquitin-like UniProtKB/TrEMBL
UniProt A0A0G2K3V1 ENTREZGENE, UniProtKB/TrEMBL
  A6IRS2 ENTREZGENE, UniProtKB/TrEMBL
  A6IRS3 ENTREZGENE, UniProtKB/TrEMBL
  A6IRS4_RAT UniProtKB/TrEMBL
  D3ZCR9_RAT UniProtKB/TrEMBL
  M0R9B9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-09 Ubxn7  UBX domain protein 7  Ubxd7  UBX domain containing 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Ubxd7  UBX domain containing 7  RGD1306346_predicted  similar to KIAA0794 protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1306346_predicted  similar to KIAA0794 protein (predicted)  LOC303878_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC303878_predicted  similar to KIAA0794 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL