Klhl22 (kelch-like family member 22) - Rat Genome Database

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Gene: Klhl22 (kelch-like family member 22) Rattus norvegicus
Analyze
Symbol: Klhl22
Name: kelch-like family member 22
RGD ID: 1306288
Description: Predicted to enable 14-3-3 protein binding activity and ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in several processes, including cellular response to L-leucine; mitotic spindle assembly checkpoint signaling; and positive regulation of TORC1 signaling. Predicted to act upstream of or within several processes, including negative regulation of T cell mediated immune response to tumor cell; negative regulation of TORC1 signaling; and regulation of type I interferon production. Predicted to be located in centrosome and cytoplasm. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytosol; mitotic spindle; and polar microtubule. Predicted to colocalize with lysosome and nucleus. Orthologous to human KLHL22 (kelch like family member 22); INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: kelch-like 22; kelch-like 22 (Drosophila); kelch-like protein 22; LOC303792; RGD1306288; similar to hypothetical protein FLJ14360
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81196,695,168 - 96,736,079 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1196,695,171 - 96,738,065 (-)EnsemblGRCr8
mRatBN7.21183,190,891 - 83,231,746 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,190,891 - 83,231,770 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1191,919,784 - 91,960,680 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01184,580,927 - 84,621,830 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01183,634,547 - 83,675,443 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01187,646,489 - 87,718,808 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,677,966 - 87,718,826 (+)Ensemblrn6Rnor6.0
Rnor_5.01190,699,112 - 90,771,253 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41185,179,262 - 85,220,103 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1181,962,736 - 82,003,585 (-)NCBICelera
RGSC_v3.11185,219,855 - 85,260,693 (-)NCBI
Cytogenetic Map11q23NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
centrosome  (IEA,ISO,ISS)
Cul3-RING ubiquitin ligase complex  (IBA,IEA,ISO,ISS)
cytoplasm  (ISO,ISS)
cytosol  (IBA,IEA,ISO,ISS)
intercellular bridge  (ISO)
lysosome  (IEA,ISO,ISS)
mitotic spindle  (IBA,ISO,ISS)
nucleus  (IBA,IEA,ISO,ISS)
polar microtubule  (IBA,ISO,ISS)
spindle  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19995937   PMID:23455478   PMID:29769719   PMID:33450132  


Genomics

Comparative Map Data
Klhl22
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81196,695,168 - 96,736,079 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1196,695,171 - 96,738,065 (-)EnsemblGRCr8
mRatBN7.21183,190,891 - 83,231,746 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,190,891 - 83,231,770 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1191,919,784 - 91,960,680 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01184,580,927 - 84,621,830 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01183,634,547 - 83,675,443 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01187,646,489 - 87,718,808 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,677,966 - 87,718,826 (+)Ensemblrn6Rnor6.0
Rnor_5.01190,699,112 - 90,771,253 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41185,179,262 - 85,220,103 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1181,962,736 - 82,003,585 (-)NCBICelera
RGSC_v3.11185,219,855 - 85,260,693 (-)NCBI
Cytogenetic Map11q23NCBI
KLHL22
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382220,441,519 - 20,495,795 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2220,441,519 - 20,496,893 (-)Ensemblhg38GRCh38
GRCh372220,795,806 - 20,850,082 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362219,125,806 - 19,180,122 (-)NCBIBuild 36Build 36hg18NCBI36
Celera224,282,529 - 4,336,886 (-)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef224,059,895 - 4,107,538 (-)NCBIHuRef
CHM1_12220,796,082 - 20,850,455 (-)NCBICHM1_1
T2T-CHM13v2.02220,845,791 - 20,900,118 (-)NCBIT2T-CHM13v2.0
Klhl22
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391617,577,485 - 17,611,246 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1617,577,482 - 17,611,246 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381617,759,621 - 17,793,382 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1617,759,618 - 17,793,382 (+)Ensemblmm10GRCm38
MGSCv371617,759,714 - 17,793,475 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361617,673,234 - 17,706,943 (+)NCBIMGSCv36mm8
Celera1618,332,703 - 18,366,464 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.01NCBI
Klhl22
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544219,009,155 - 19,051,393 (-)Ensembl
ChiLan1.0NW_00495544219,010,971 - 19,051,300 (-)NCBIChiLan1.0ChiLan1.0
KLHL22
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22330,062,468 - 30,116,957 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12232,609,513 - 32,664,017 (-)NCBINHGRI_mPanPan1
PanPan1.12219,126,658 - 19,174,839 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2219,122,875 - 19,174,842 (-)EnsemblpanPan2panpan1.1
KLHL22
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12630,248,253 - 30,281,989 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2630,248,240 - 30,281,843 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2630,207,137 - 30,246,532 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02631,656,570 - 31,696,204 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2631,656,561 - 31,696,176 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12629,702,711 - 29,742,120 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02629,327,051 - 29,366,309 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02630,416,255 - 30,455,878 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Klhl22
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118139,854,676 - 139,899,247 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366192,854,803 - 2,899,460 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366192,854,915 - 2,899,386 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHL22
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1450,773,964 - 50,809,986 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11450,773,917 - 50,809,991 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21454,334,392 - 54,451,824 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLHL22
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1195,211,732 - 5,264,953 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl195,218,653 - 5,265,063 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660851,671,542 - 1,725,149 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klhl22
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624945408,999 - 441,975 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624945409,093 - 446,619 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Klhl22
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v143,018,982 - 3,058,024 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:65
Count of miRNA genes:59
Interacting mature miRNAs:62
Transcripts:ENSRNOT00000068711
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117961851999753367Rat

Markers in Region
RH138822  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21183,191,424 - 83,191,545 (-)MAPPERmRatBN7.2
Rnor_6.01187,718,154 - 87,718,274NCBIRnor6.0
Rnor_5.01190,770,599 - 90,770,719UniSTSRnor5.0
RGSC_v3.41185,179,793 - 85,179,913UniSTSRGSC3.4
Celera1181,963,267 - 81,963,387UniSTS
RH 3.4 Map11710.1UniSTS
Cytogenetic Map11q23UniSTS
RH131807  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21183,191,027 - 83,191,210 (-)MAPPERmRatBN7.2
Rnor_6.01187,718,489 - 87,718,671NCBIRnor6.0
Rnor_5.01190,770,934 - 90,771,116UniSTSRnor5.0
RGSC_v3.41185,179,396 - 85,179,578UniSTSRGSC3.4
Celera1181,962,870 - 81,963,052UniSTS
RH 3.4 Map11707.6UniSTS
Cytogenetic Map11q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000068711   ⟹   ENSRNOP00000063573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1196,695,171 - 96,735,844 (-)Ensembl
mRatBN7.2 Ensembl1183,190,891 - 83,231,770 (-)Ensembl
Rnor_6.0 Ensembl1187,677,966 - 87,718,805 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000091675   ⟹   ENSRNOP00000075207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1196,695,171 - 96,736,015 (-)Ensembl
mRatBN7.2 Ensembl1183,190,891 - 83,231,748 (-)Ensembl
Rnor_6.0 Ensembl1187,678,295 - 87,718,826 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000166570   ⟹   ENSRNOP00000112391
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1196,695,171 - 96,736,015 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000169466   ⟹   ENSRNOP00000098694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1196,695,171 - 96,738,065 (-)Ensembl
RefSeq Acc Id: NM_001107079   ⟹   NP_001100549
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81196,695,171 - 96,736,015 (-)NCBI
mRatBN7.21183,190,894 - 83,231,738 (-)NCBI
Rnor_6.01187,677,966 - 87,718,805 (+)NCBI
Rnor_5.01190,699,112 - 90,771,253 (+)NCBI
RGSC_v3.41185,179,262 - 85,220,103 (-)RGD
Celera1181,962,736 - 82,003,585 (-)RGD
Sequence:
RefSeq Acc Id: XM_006248699   ⟹   XP_006248761
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81196,695,168 - 96,735,878 (-)NCBI
mRatBN7.21183,190,891 - 83,231,670 (-)NCBI
Rnor_6.01187,678,203 - 87,718,808 (+)NCBI
Rnor_5.01190,699,112 - 90,771,253 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006248700   ⟹   XP_006248762
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81196,695,168 - 96,735,879 (-)NCBI
mRatBN7.21183,190,891 - 83,231,671 (-)NCBI
Rnor_6.01187,678,202 - 87,718,808 (+)NCBI
Rnor_5.01190,699,112 - 90,771,253 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063270457   ⟹   XP_063126527
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81196,695,168 - 96,736,079 (-)NCBI
RefSeq Acc Id: XM_063270458   ⟹   XP_063126528
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81196,695,168 - 96,731,415 (-)NCBI
RefSeq Acc Id: NP_001100549   ⟸   NM_001107079
- UniProtKB: D4A9W5 (UniProtKB/Swiss-Prot),   D3ZZC3 (UniProtKB/Swiss-Prot),   A0A0G2KA06 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248762   ⟸   XM_006248700
- Peptide Label: isoform X2
- UniProtKB: A0A0G2KA06 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248761   ⟸   XM_006248699
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QUL2 (UniProtKB/TrEMBL),   A0A0G2KA06 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000063573   ⟸   ENSRNOT00000068711
Ensembl Acc Id: ENSRNOP00000075207   ⟸   ENSRNOT00000091675
RefSeq Acc Id: XP_063126527   ⟸   XM_063270457
- Peptide Label: isoform X3
- UniProtKB: A0A0G2KA06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126528   ⟸   XM_063270458
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000112391   ⟸   ENSRNOT00000166570
Ensembl Acc Id: ENSRNOP00000098694   ⟸   ENSRNOT00000169466
Protein Domains
BTB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZZC3-F1-model_v2 AlphaFold D3ZZC3 1-634 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698324
Promoter ID:EPDNEW_R8849
Type:initiation region
Name:Klhl22_1
Description:kelch-like family member 22
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01187,677,946 - 87,678,006EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306288 AgrOrtholog
BioCyc Gene G2FUF-20611 BioCyc
Ensembl Genes ENSRNOG00000001878 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000068711 ENTREZGENE
  ENSRNOT00000166570 ENTREZGENE
Gene3D-CATH 1.25.40.420 UniProtKB/Swiss-Prot
  2.120.10.80 UniProtKB/Swiss-Prot
  Potassium Channel Kv1.1, Chain A UniProtKB/Swiss-Prot
InterPro BACK UniProtKB/Swiss-Prot
  BTB-kelch_protein UniProtKB/Swiss-Prot
  BTB/POZ_dom UniProtKB/Swiss-Prot
  Kelch-typ_b-propeller UniProtKB/Swiss-Prot
  Kelch_1 UniProtKB/Swiss-Prot
  KLHL22 UniProtKB/Swiss-Prot
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot
KEGG Report rno:303792 UniProtKB/Swiss-Prot
NCBI Gene 303792 ENTREZGENE
PANTHER LD33804P UniProtKB/Swiss-Prot
  PTHR45632:SF5 UniProtKB/Swiss-Prot
Pfam BACK UniProtKB/Swiss-Prot
  BTB UniProtKB/Swiss-Prot
  Kelch_1 UniProtKB/Swiss-Prot
  Kelch_KLHDC2_KLHL20_DRC7 UniProtKB/Swiss-Prot
PhenoGen Klhl22 PhenoGen
PIRSF Kelch-like_protein_gigaxonin UniProtKB/Swiss-Prot
PROSITE BTB UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001878 RatGTEx
SMART BACK UniProtKB/Swiss-Prot
  BTB UniProtKB/Swiss-Prot
  Kelch UniProtKB/Swiss-Prot
Superfamily-SCOP SSF117281 UniProtKB/Swiss-Prot
  SSF54695 UniProtKB/Swiss-Prot
UniProt A0A0G2KA06 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QUL2 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L7R8_RAT UniProtKB/TrEMBL
  D3ZZC3 ENTREZGENE
  D4A9W5 ENTREZGENE
  KLH22_RAT UniProtKB/Swiss-Prot
UniProt Secondary D4A9W5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-06 Klhl22  kelch-like family member 22  Klhl22  kelch-like 22 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Klhl22  kelch-like 22 (Drosophila)   Klhl22_predicted  kelch-like 22 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Klhl22_predicted  kelch-like 22 (Drosophila) (predicted)  RGD1306288_predicted  similar to hypothetical protein FLJ14360 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1306288_predicted  similar to hypothetical protein FLJ14360 (predicted)  LOC303792_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC303792_predicted  similar to hypothetical protein FLJ14360 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL