Sipa1l2 (signal-induced proliferation-associated 1 like 2) - Rat Genome Database

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Gene: Sipa1l2 (signal-induced proliferation-associated 1 like 2) Rattus norvegicus
Analyze
Symbol: Sipa1l2
Name: signal-induced proliferation-associated 1 like 2
RGD ID: 1306269
Description: Predicted to enable GTPase activator activity. Predicted to be involved in presynaptic signal transduction. Is active in glutamatergic synapse; postsynaptic density, intracellular component; and presynapse. Orthologous to human SIPA1L2 (signal induced proliferation associated 1 like 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC361442; serine-rich synapse associated protein 2; serine-rich synapse-associated protein; Sersap2; signal-induced proliferation-associated 1-like protein 2; SIPA1-like protein 2; Spar2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81970,287,134 - 70,437,810 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1970,287,147 - 70,437,773 (-)EnsemblGRCr8
mRatBN7.21953,389,792 - 53,540,466 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1953,389,805 - 53,540,428 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1960,176,222 - 60,332,340 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01961,032,682 - 61,188,617 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01963,108,630 - 63,264,577 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01958,236,201 - 58,399,842 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1958,236,214 - 58,399,816 (-)Ensemblrn6Rnor6.0
Rnor_5.01968,936,975 - 69,098,880 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41955,622,546 - 55,775,008 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1952,750,929 - 52,853,027 (-)NCBICelera
RGSC_v3.11955,627,428 - 55,779,889 (-)NCBI
Cytogenetic Map19q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
High Myopia  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
amphetamine  (EXP)
aristolochic acid A  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
cantharidin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroacetaldehyde  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
clothianidin  (ISO)
cobalt dichloride  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
diallyl trisulfide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenvalerate  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glyphosate  (ISO)
ifosfamide  (ISO)
isoflurane  (ISO)
leflunomide  (ISO)
manganese(II) chloride  (EXP)
mercury dibromide  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
propiconazole  (EXP)
SB 431542  (ISO)
sevoflurane  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
testosterone  (ISO)
tetraphene  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals. Andres-Alonso M, etal., Nat Commun. 2019 Nov 29;10(1):5448. doi: 10.1038/s41467-019-13224-z.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. SPAR2, a novel SPAR-related protein with GAP activity for Rap1 and Rap2. Spilker C, etal., J Neurochem. 2008 Jan;104(1):187-201. doi: 10.1111/j.1471-4159.2007.04991.x. Epub 2007 Oct 24.
Additional References at PubMed
PMID:25931508   PMID:30706531  


Genomics

Comparative Map Data
Sipa1l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81970,287,134 - 70,437,810 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1970,287,147 - 70,437,773 (-)EnsemblGRCr8
mRatBN7.21953,389,792 - 53,540,466 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1953,389,805 - 53,540,428 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1960,176,222 - 60,332,340 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01961,032,682 - 61,188,617 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01963,108,630 - 63,264,577 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01958,236,201 - 58,399,842 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1958,236,214 - 58,399,816 (-)Ensemblrn6Rnor6.0
Rnor_5.01968,936,975 - 69,098,880 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41955,622,546 - 55,775,008 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1952,750,929 - 52,853,027 (-)NCBICelera
RGSC_v3.11955,627,428 - 55,779,889 (-)NCBI
Cytogenetic Map19q12NCBI
SIPA1L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381232,397,965 - 232,630,496 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1232,397,622 - 232,631,404 (-)Ensemblhg38GRCh38
GRCh371232,533,711 - 232,766,242 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361230,600,334 - 230,717,866 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1205,802,459 - 205,919,973 (-)NCBICelera
Cytogenetic Map1q42.2NCBI
HuRef1203,022,217 - 203,139,810 (-)NCBIHuRef
CHM1_11233,807,559 - 233,925,042 (-)NCBICHM1_1
T2T-CHM13v2.01231,783,662 - 232,016,327 (-)NCBIT2T-CHM13v2.0
Sipa1l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398126,144,807 - 126,296,602 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8126,144,802 - 126,296,547 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm388125,418,068 - 125,569,863 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8125,418,063 - 125,569,808 (-)Ensemblmm10GRCm38
MGSCv378127,941,963 - 128,016,610 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368128,304,153 - 128,455,916 (-)NCBIMGSCv36mm8
Celera8129,732,717 - 129,807,059 (-)NCBICelera
Cytogenetic Map8E2NCBI
cM Map873.63NCBI
Sipa1l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554926,534,165 - 6,709,135 (+)Ensembl
ChiLan1.0NW_0049554926,611,430 - 6,709,016 (+)NCBIChiLan1.0ChiLan1.0
SIPA1L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2116,575,631 - 16,810,753 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1116,771,642 - 17,006,582 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01207,944,776 - 208,180,227 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11212,966,017 - 213,177,329 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1212,966,023 - 213,101,179 (-)EnsemblpanPan2panpan1.1
SIPA1L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.147,024,936 - 7,238,268 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl47,071,645 - 7,237,090 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha47,012,971 - 7,226,332 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.047,047,657 - 7,261,112 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl47,047,336 - 7,260,591 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.147,057,294 - 7,269,791 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.047,176,930 - 7,390,556 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.047,401,471 - 7,614,980 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Sipa1l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934442,622,403 - 42,700,633 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648418,787,338 - 18,865,991 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648418,787,633 - 18,865,859 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SIPA1L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1458,117,570 - 58,352,504 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11458,116,906 - 58,352,507 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21462,424,381 - 62,588,239 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SIPA1L2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12569,616,236 - 69,732,476 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2569,615,794 - 69,732,519 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605571,537,039 - 71,769,134 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sipa1l2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477517,413,241 - 17,504,344 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477517,321,335 - 17,504,357 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Sipa1l2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11744,935,261 - 45,086,248 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:150
Count of miRNA genes:114
Interacting mature miRNAs:122
Transcripts:ENSRNOT00000026843
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)196124916174246245Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat

Markers in Region
BF390033  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21953,509,315 - 53,509,455 (+)MAPPERmRatBN7.2
Rnor_6.01958,355,675 - 58,355,814NCBIRnor6.0
Rnor_5.01969,056,388 - 69,056,527UniSTSRnor5.0
RGSC_v3.41955,744,004 - 55,744,143UniSTSRGSC3.4
Celera1952,870,366 - 52,870,505UniSTS
RH 3.4 Map19736.1UniSTS
Cytogenetic Map19q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 91 59 6 355 191 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000026843   ⟹   ENSRNOP00000026843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1970,287,147 - 70,437,773 (-)Ensembl
mRatBN7.2 Ensembl1953,389,805 - 53,540,428 (-)Ensembl
Rnor_6.0 Ensembl1958,236,214 - 58,399,816 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095461   ⟹   ENSRNOP00000084823
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1970,288,216 - 70,437,773 (-)Ensembl
mRatBN7.2 Ensembl1953,390,874 - 53,540,428 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096967   ⟹   ENSRNOP00000078337
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1970,287,147 - 70,437,773 (-)Ensembl
mRatBN7.2 Ensembl1953,389,805 - 53,540,428 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112190   ⟹   ENSRNOP00000080159
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1970,287,147 - 70,437,773 (-)Ensembl
mRatBN7.2 Ensembl1953,389,805 - 53,540,428 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000138589   ⟹   ENSRNOP00000109270
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1970,287,147 - 70,437,773 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000159211   ⟹   ENSRNOP00000111286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1970,287,147 - 70,437,773 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000159555   ⟹   ENSRNOP00000104554
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1970,287,147 - 70,437,773 (-)Ensembl
RefSeq Acc Id: NM_001009704   ⟹   NP_001009704
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81970,287,147 - 70,437,773 (-)NCBI
mRatBN7.21953,389,805 - 53,540,428 (-)NCBI
Rnor_6.01958,236,214 - 58,399,816 (-)NCBI
Rnor_5.01968,936,975 - 69,098,880 (-)NCBI
RGSC_v3.41955,622,546 - 55,775,008 (-)RGD
Celera1952,750,929 - 52,853,027 (-)RGD
Sequence:
RefSeq Acc Id: XM_008772638   ⟹   XP_008770860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81970,287,134 - 70,437,810 (-)NCBI
mRatBN7.21953,389,792 - 53,540,466 (-)NCBI
Rnor_6.01958,236,201 - 58,399,842 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008772639   ⟹   XP_008770861
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81970,287,134 - 70,437,810 (-)NCBI
mRatBN7.21953,389,792 - 53,540,466 (-)NCBI
Rnor_6.01958,236,201 - 58,399,842 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039097900   ⟹   XP_038953828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81970,287,134 - 70,437,810 (-)NCBI
mRatBN7.21953,389,792 - 53,540,466 (-)NCBI
RefSeq Acc Id: XM_039097901   ⟹   XP_038953829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81970,287,134 - 70,437,810 (-)NCBI
mRatBN7.21953,389,792 - 53,540,466 (-)NCBI
RefSeq Acc Id: NP_001009704   ⟸   NM_001009704
- UniProtKB: Q5JCS6 (UniProtKB/Swiss-Prot),   F1M8G8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770861   ⟸   XM_008772639
- Peptide Label: isoform X4
- UniProtKB: Q5JCS6 (UniProtKB/Swiss-Prot),   A0A8I5ZPJ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770860   ⟸   XM_008772638
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000026843   ⟸   ENSRNOT00000026843
RefSeq Acc Id: XP_038953829   ⟸   XM_039097901
- Peptide Label: isoform X3
- UniProtKB: Q5JCS6 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038953828   ⟸   XM_039097900
- Peptide Label: isoform X1
- UniProtKB: Q5JCS6 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSRNOP00000078337   ⟸   ENSRNOT00000096967
Ensembl Acc Id: ENSRNOP00000084823   ⟸   ENSRNOT00000095461
Ensembl Acc Id: ENSRNOP00000080159   ⟸   ENSRNOT00000112190
Ensembl Acc Id: ENSRNOP00000111286   ⟸   ENSRNOT00000159211
Ensembl Acc Id: ENSRNOP00000109270   ⟸   ENSRNOT00000138589
Ensembl Acc Id: ENSRNOP00000104554   ⟸   ENSRNOT00000159555
Protein Domains
PDZ   Rap-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5JCS6-F1-model_v2 AlphaFold Q5JCS6 1-1722 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701248
Promoter ID:EPDNEW_R11771
Type:multiple initiation site
Name:Sipa1l2_1
Description:signal-induced proliferation-associated 1 like 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01958,399,833 - 58,399,893EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306269 AgrOrtholog
BioCyc Gene G2FUF-5210 BioCyc
Ensembl Genes ENSRNOG00000019791 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000026843 ENTREZGENE
  ENSRNOT00000096967 ENTREZGENE
  ENSRNOT00000112190 ENTREZGENE
  ENSRNOT00000159211 ENTREZGENE
  ENSRNOT00000159555 ENTREZGENE
Gene3D-CATH 2.30.42.10 UniProtKB/Swiss-Prot
  3.40.50.11210 UniProtKB/Swiss-Prot
  6.10.140.210 UniProtKB/Swiss-Prot
InterPro PDZ UniProtKB/Swiss-Prot
  PDZ_sf UniProtKB/Swiss-Prot
  Rap/Ran-GAP_sf UniProtKB/Swiss-Prot
  Rap1_Ran_GAP UniProtKB/Swiss-Prot
  Rap_GAP_dom UniProtKB/Swiss-Prot
  SIPA1L_C UniProtKB/Swiss-Prot
KEGG Report rno:361442 UniProtKB/Swiss-Prot
NCBI Gene 361442 ENTREZGENE
PANTHER PTHR15711:SF7 UniProtKB/Swiss-Prot
  RAP GTPASE-ACTIVATING PROTEIN UniProtKB/Swiss-Prot
Pfam PDZ UniProtKB/Swiss-Prot
  Rap-GAP_dimer UniProtKB/Swiss-Prot
  Rap_GAP UniProtKB/Swiss-Prot
  SPAR_C UniProtKB/Swiss-Prot
PhenoGen Sipa1l2 PhenoGen
PROSITE PDZ UniProtKB/Swiss-Prot
  RAPGAP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000019791 RatGTEx
SMART PDZ UniProtKB/Swiss-Prot
Superfamily-SCOP SSF111347 UniProtKB/Swiss-Prot
  SSF50156 UniProtKB/Swiss-Prot
UniProt A0A8I5ZPJ4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZY04_RAT UniProtKB/TrEMBL
  A0A8I6G2L5 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LNL3_RAT UniProtKB/TrEMBL
  A0ABK0LT82_RAT UniProtKB/TrEMBL
  A0ABK0LZX0_RAT UniProtKB/TrEMBL
  F1M8G8 ENTREZGENE, UniProtKB/TrEMBL
  Q5JCS6 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Sipa1l2  signal-induced proliferation-associated 1 like 2  Sipa1l2_predicted  signal-induced proliferation-associated 1 like 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Sipa1l2_predicted  signal-induced proliferation-associated 1 like 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED