Pkd2l1 (polycystin 2 like 1, transient receptor potential cation channel) - Rat Genome Database

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Gene: Pkd2l1 (polycystin 2 like 1, transient receptor potential cation channel) Rattus norvegicus
Analyze
Symbol: Pkd2l1
Name: polycystin 2 like 1, transient receptor potential cation channel
RGD ID: 1306261
Description: Predicted to enable several functions, including monoatomic ion channel activity; muscle alpha-actinin binding activity; and transmembrane transporter binding activity. Predicted to contribute to monoatomic cation channel activity and sour taste receptor activity. Predicted to be involved in several processes, including detection of chemical stimulus involved in sensory perception of sour taste; monoatomic cation transmembrane transport; and protein homotetramerization. Predicted to be located in several cellular components, including cell surface; endoplasmic reticulum; and non-motile cilium. Predicted to be part of calcium channel complex and receptor complex. Predicted to be active in membrane. Orthologous to human PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; acrylamide; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC293937; polycystic kidney disease 2-like 1; polycystin-2-like protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81252,982,096 - 253,019,235 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1252,982,096 - 253,023,359 (-)EnsemblGRCr8
mRatBN7.21243,032,891 - 243,070,031 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1243,032,913 - 243,070,031 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1251,182,946 - 251,220,300 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01257,879,666 - 257,916,994 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01250,533,109 - 250,570,461 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01263,922,201 - 263,959,318 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1263,922,201 - 263,959,318 (-)Ensemblrn6Rnor6.0
Rnor_5.01271,367,373 - 271,404,490 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41249,047,374 - 249,084,997 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1238,850,066 - 238,887,164 (-)NCBICelera
RGSC_v3.11249,083,071 - 249,342,077 (+)NCBI
Cytogenetic Map1q54NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10517637   PMID:11959145   PMID:12809519   PMID:15548533   PMID:16891422   PMID:17944866   PMID:19812697   PMID:20408813   PMID:20538909   PMID:22193359   PMID:24336288   PMID:24336289  
PMID:28553944   PMID:28904867   PMID:29567962   PMID:30004384   PMID:37686387  


Genomics

Comparative Map Data
Pkd2l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81252,982,096 - 253,019,235 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1252,982,096 - 253,023,359 (-)EnsemblGRCr8
mRatBN7.21243,032,891 - 243,070,031 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1243,032,913 - 243,070,031 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1251,182,946 - 251,220,300 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01257,879,666 - 257,916,994 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01250,533,109 - 250,570,461 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01263,922,201 - 263,959,318 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1263,922,201 - 263,959,318 (-)Ensemblrn6Rnor6.0
Rnor_5.01271,367,373 - 271,404,490 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41249,047,374 - 249,084,997 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1238,850,066 - 238,887,164 (-)NCBICelera
RGSC_v3.11249,083,071 - 249,342,077 (+)NCBI
Cytogenetic Map1q54NCBI
PKD2L1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810100,288,149 - 100,330,228 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10100,288,149 - 100,330,264 (-)Ensemblhg38GRCh38
GRCh3710102,047,906 - 102,089,985 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610102,037,893 - 102,080,233 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3410102,037,892 - 102,080,233NCBI
Celera1095,785,781 - 95,828,122 (-)NCBICelera
Cytogenetic Map10q24.31NCBI
HuRef1095,676,807 - 95,719,121 (-)NCBIHuRef
CHM1_110102,332,503 - 102,374,685 (-)NCBICHM1_1
T2T-CHM13v2.010101,172,443 - 101,214,450 (-)NCBIT2T-CHM13v2.0
Pkd2l1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391944,136,076 - 44,235,355 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1944,136,076 - 44,180,881 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381944,147,637 - 44,248,328 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1944,147,637 - 44,192,442 (-)Ensemblmm10GRCm38
MGSCv371944,222,127 - 44,266,932 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361944,200,948 - 44,245,719 (-)NCBIMGSCv36mm8
Celera1944,933,088 - 44,971,513 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1936.91NCBI
Pkd2l1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555076,146,825 - 6,166,976 (-)Ensembl
ChiLan1.0NW_0049555076,145,981 - 6,167,152 (-)NCBIChiLan1.0ChiLan1.0
PKD2L1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28112,172,821 - 112,215,281 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110112,178,140 - 112,220,600 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01096,889,228 - 96,932,177 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110100,370,083 - 100,412,366 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10100,370,083 - 100,412,366 (-)EnsemblpanPan2panpan1.1
PKD2L1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12813,045,749 - 13,076,072 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2813,045,829 - 13,076,485 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2813,228,826 - 13,259,097 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02813,514,442 - 13,544,711 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2813,514,692 - 13,544,618 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12813,061,160 - 13,091,425 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02813,099,244 - 13,129,512 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02813,233,508 - 13,263,795 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pkd2l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721333,959,016 - 33,960,778 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004944487205 - 1,593 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PKD2L1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14111,399,071 - 111,460,995 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.114111,398,704 - 111,434,584 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214120,901,637 - 120,937,562 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PKD2L1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1993,319,408 - 93,363,389 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604854,321,567 - 54,368,696 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pkd2l1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473712,102,976 - 12,137,737 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473712,097,134 - 12,137,574 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Pkd2l1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1243,678,657 - 43,714,462 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pkd2l1
104 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:120
Count of miRNA genes:90
Interacting mature miRNAs:105
Transcripts:ENSRNOT00000068007
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1160111531262090437Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753266453731Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1186658830266453731Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1210980612255980612Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1226175591270518180Rat
1578775Iddm21Insulin dependent diabetes mellitus QTL 214.13blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1245782829270518180Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1205233991267096252Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1218829748263829748Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1186658830266453731Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
631837Niddm35Non-insulin dependent diabetes mellitus QTL 350.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1248619887269633915Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1176288899270518180Rat
631836Stl31Serum triglyceride level QTL 314.645e-06blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1247133834270518180Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1162548015270518180Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1210980612255980612Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1160111531262090437Rat
1300108Rf8Renal function QTL 83.75renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1237995023269633915Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1233480549270108840Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1200449456256003563Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1234540191270518180Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1233480549270108840Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1207163993269633915Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1210980612255980612Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
724538Kidm1Kidney mass QTL 13.2kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1223134011262090599Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1210980612255980612Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1160111426262090599Rat
2314011Gluco56Glucose level QTL 56blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1209203273254203273Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1225108840270108840Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1228180370266453608Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1208479811269633915Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1224633915269633915Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1232312773270518180Rat
2316896Gluco57Glucose level QTL 577.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1238398865255849249Rat
1358916Kidm22Kidney mass QTL 223.32kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1212738576257738576Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1194786607262083703Rat
2292218Kidm35Kidney mass QTL 35kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1208798288253798288Rat
61400Niddm1Non-insulin dependent diabetes mellitus QTL 111blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1228180243255849249Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
2293700Bmd27Bone mineral density QTL 276.60.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1210980612255980612Rat
2293701Bmd34Bone mineral density QTL 348.30.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)1210980612255980612Rat
7387289Uae45Urinary albumin excretion QTL 452.860.0021urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1233204160270518180Rat
1581544Rf52Renal function QTL 520.05urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)1241569529269633915Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1210980612255980612Rat
631536Lnnr2Liver neoplastic nodule remodeling QTL 22.90.0005liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)1243953669270518180Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1185857683270518180Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1226175591270518180Rat
631669Iddm9Insulin dependent diabetes mellitus QTL 92.80.039blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1233349180270518180Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1210980612255980612Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1228174566270518180Rat

Markers in Region
D1Rat451  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81252,997,810 - 252,997,999 (+)Marker Load Pipeline
Rnor_5.01271,383,064 - 271,383,254NCBIRnor5.0
RGSC_v3.41249,069,116 - 249,069,305UniSTSRGSC3.4
RH 3.4 Map11618.11UniSTS
RH 3.4 Map11618.11RGD
RH 2.0 Map11222.7RGD
SHRSP x BN Map1136.8299RGD
Cytogenetic Map1q54UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
6 12 18 51 47 37 19 19 19 6 152 67 8 29 52 75 18 4 4

Sequence


Ensembl Acc Id: ENSRNOT00000068007   ⟹   ENSRNOP00000062794
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1252,982,096 - 253,023,359 (-)Ensembl
mRatBN7.2 Ensembl1243,032,913 - 243,070,031 (-)Ensembl
Rnor_6.0 Ensembl1263,922,201 - 263,959,318 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096694   ⟹   ENSRNOP00000082663
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1252,982,096 - 253,019,235 (-)Ensembl
mRatBN7.2 Ensembl1243,032,913 - 243,070,031 (-)Ensembl
RefSeq Acc Id: NM_001415836   ⟹   NP_001402765
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81252,982,096 - 253,019,235 (-)NCBI
mRatBN7.21243,032,891 - 243,070,031 (-)NCBI
RefSeq Acc Id: NM_001415837   ⟹   NP_001402766
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81252,982,096 - 253,000,948 (-)NCBI
mRatBN7.21243,032,891 - 243,051,744 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001402765 (Get FASTA)   NCBI Sequence Viewer  
  NP_001402766 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL94276 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000062794.2
  ENSRNOP00000082663
  ENSRNOP00000082663.1
Ensembl Acc Id: ENSRNOP00000062794   ⟸   ENSRNOT00000068007
Ensembl Acc Id: ENSRNOP00000082663   ⟸   ENSRNOT00000096694
RefSeq Acc Id: NP_001402765   ⟸   NM_001415836
- Peptide Label: isoform 1
- UniProtKB: A0A8I6G7P9 (UniProtKB/TrEMBL),   A6JHF2 (UniProtKB/TrEMBL),   D3ZDT6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001402766   ⟸   NM_001415837
- Peptide Label: isoform 2
- UniProtKB: A6JHF2 (UniProtKB/TrEMBL),   D3ZDT6 (UniProtKB/TrEMBL)
Protein Domains
Polycystin   Polycystin cation channel PKD1/PKD2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZDT6-F1-model_v2 AlphaFold D3ZDT6 1-676 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306261 AgrOrtholog
BioCyc Gene G2FUF-55607 BioCyc
Ensembl Genes ENSRNOG00000012591 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000068007.3 UniProtKB/TrEMBL
  ENSRNOT00000096694 ENTREZGENE
  ENSRNOT00000096694.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  1.20.120.350 UniProtKB/TrEMBL
  1.20.5.340 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro PKD1_2_channel UniProtKB/TrEMBL
  PKD_2 UniProtKB/TrEMBL
  Polycystin UniProtKB/TrEMBL
  Polycystin_dom UniProtKB/TrEMBL
  Volt_channel_dom_sf UniProtKB/TrEMBL
NCBI Gene 293937 ENTREZGENE
PANTHER POLYCYSTIN FAMILY MEMBER UniProtKB/TrEMBL
  POLYCYSTIN-2-LIKE PROTEIN 1 UniProtKB/TrEMBL
Pfam Fer4_24 UniProtKB/TrEMBL
  PKD_channel UniProtKB/TrEMBL
  Polycystin_dom UniProtKB/TrEMBL
PhenoGen Pkd2l1 PhenoGen
PRINTS POLYCYSTIN2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012591 RatGTEx
Superfamily-SCOP Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A8I6G7P9 ENTREZGENE, UniProtKB/TrEMBL
  A6JHF2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZDT6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-03 Pkd2l1  polycystin 2 like 1, transient receptor potential cation channel  Pkd2l1  polycystic kidney disease 2-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Pkd2l1  polycystic kidney disease 2-like 1   Pkd2l1_predicted  polycystic kidney disease 2-like 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Pkd2l1_predicted  polycystic kidney disease 2-like 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED