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Gene: Pcp2 (Purkinje cell protein 2) Rattus norvegicus

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Symbol:

Pcp2

Name:

Purkinje cell protein 2

RGD ID:

1306217

Description:

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to act upstream of or within G protein-coupled opsin signaling pathway. Orthologous to human PCP2 (Purkinje cell protein 2); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; Brodifacoum.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC304195; Purkinje cell protein 2 (L7); Purkinje cell protein 2 homolog

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PCP2 (Purkinje cell protein 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL
Mus musculus (house mouse):	Pcp2 (Purkinje cell protein 2 (L7))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pcp2 (Purkinje cell protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PCP2 (Purkinje cell protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PCP2 (Purkinje cell protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pcp2 (Purkinje cell protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PCP2 (Purkinje cell protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PCP2 (Purkinje cell protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pcp2 (Purkinje cell protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Pcp2 (Purkinje cell protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	MED13L (mediator complex subunit 13L)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	PCP2 (Purkinje cell protein 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Pcp2 (Purkinje cell protein 2 (L7))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	pcp2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	6,479,554 - 6,481,550 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	6,479,554 - 6,485,159 (-)	Ensembl				GRCr8
mRatBN7.2	12	1,681,659 - 1,683,899 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	1,681,659 - 1,683,899 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	2,348,255 - 2,350,030 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	2,971,828 - 2,973,603 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	1,742,787 - 1,744,561 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	2,172,378 - 2,174,674 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	2,172,378 - 2,174,131 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	4,334,710 - 4,337,006 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	2,529,953 - 2,531,706 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	3,537,435 - 3,539,188 (-)	NCBI		Celera
RGSC_v3.1	12	2,529,954 - 2,531,703 (+)	NCBI
Cytogenetic Map	12	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,4'-trichlorobiphenyl (ISO)

6-propyl-2-thiouracil (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

Brodifacoum (EXP)

cadmium dichloride (EXP,ISO)

chlorohydrocarbon (EXP)

chrysene (ISO)

cisplatin (ISO)

Cuprizon (EXP)

D-mannitol (ISO)

Dibutyl phosphate (ISO)

fipronil (EXP)

leflunomide (ISO)

maneb (ISO)

paracetamol (ISO)

paraquat (ISO)

PCB138 (ISO)

sunitinib (ISO)

tetraphene (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G protein-coupled opsin signaling pathway (ISO)

Molecular Function

GTPase regulator activity (IEA)

guanyl-nucleotide exchange factor activity (IBA,IEA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:10196137	PMID:18768681

Genomics

Comparative Map Data

Pcp2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	6,479,554 - 6,481,550 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	6,479,554 - 6,485,159 (-)	Ensembl				GRCr8
mRatBN7.2	12	1,681,659 - 1,683,899 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	1,681,659 - 1,683,899 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	2,348,255 - 2,350,030 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	2,971,828 - 2,973,603 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	1,742,787 - 1,744,561 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	2,172,378 - 2,174,674 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	2,172,378 - 2,174,131 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	4,334,710 - 4,337,006 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	2,529,953 - 2,531,706 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	3,537,435 - 3,539,188 (-)	NCBI		Celera
RGSC_v3.1	12	2,529,954 - 2,531,703 (+)	NCBI
Cytogenetic Map	12	p12	NCBI

PCP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	7,631,615 - 7,637,006 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	7,631,611 - 7,633,719 (-)	Ensembl			hg38	GRCh38
GRCh37	19	7,696,501 - 7,698,605 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	7,602,507 - 7,604,570 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	19	7,567,691 - 7,569,754 (-)	NCBI		Celera
Cytogenetic Map	19	p13.2	NCBI
HuRef	19	7,366,217 - 7,368,354 (-)	NCBI		HuRef
CHM1_1	19	7,696,252 - 7,698,385 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	7,632,498 - 7,637,891 (-)	NCBI		T2T-CHM13v2.0

Pcp2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	3,673,369 - 3,675,547 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	3,673,371 - 3,675,545 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	8	3,623,369 - 3,625,547 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	3,623,371 - 3,625,545 (-)	Ensembl			mm10	GRCm38
MGSCv37	8	3,623,371 - 3,625,545 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	8	3,623,371 - 3,625,282 (-)	NCBI		MGSCv36	mm8
Celera	8	3,853,700 - 3,855,874 (-)	NCBI		Celera
Cytogenetic Map	8	A1.1	NCBI
cM Map	8	1.92	NCBI

Pcp2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955563	1,625,254 - 1,628,776 (+)	Ensembl
ChiLan1.0	NW_004955563	1,625,249 - 1,628,776 (+)	NCBI	ChiLan1.0	ChiLan1.0

PCP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	12,302,549 - 12,304,724 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	11,420,138 - 11,422,324 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	6,921,350 - 6,923,618 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	7,776,331 - 7,781,719 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	7,776,331 - 7,779,241 (-)	Ensembl			panPan2	panpan1.1

PCP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	52,407,707 - 52,413,061 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	52,407,776 - 52,409,628 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	52,211,780 - 52,217,150 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	52,937,009 - 52,942,382 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	52,937,078 - 52,938,930 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	52,140,808 - 52,146,178 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	52,584,397 - 52,589,765 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	52,815,402 - 52,820,769 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Pcp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	213,151,379 - 213,153,225 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	4,680,060 - 4,683,381 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936588	4,681,559 - 4,683,443 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PCP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	71,471,417 - 71,519,421 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	71,471,071 - 71,519,394 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	71,913,237 - 71,915,643 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PCP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	7,118,091 - 7,123,489 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	7,116,214 - 7,119,967 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666081	738,088 - 743,514 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pcp2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	713,799 - 715,442 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624828	713,796 - 719,287 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Pcp2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	16	1,548,035 - 1,550,097 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Pcp2
4 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	74
Count of miRNA genes:	69
Interacting mature miRNAs:	74
Transcripts:	ENSRNOT00000001313
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312418	Kidm41	Kidney mass QTL 41	3.7	0.0001	kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	12	5921918	25247790	Rat
724526	Uae3	Urinary albumin excretion QTL 3	4.9	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	12	1	15486827	Rat
2306789	Ean6	Experimental allergic neuritis QTL 6	4.9		nervous system integrity trait (VT:0010566)	experimental autoimmune neuritis severity score (CMO:0001528)	12	1	29775522	Rat
7204484	Bp358	Blood pressure QTL 358		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	1	24849755	Rat
7387292	Kidm42	Kidney mass QTL 42	3.03	0.0004	kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	12	1	41361854	Rat
1357337	Gluco3	Glucose level QTL 3		0.0004	adipocyte glucose uptake trait (VT:0004185)	absolute change in adipocyte glucose uptake (CMO:0000873)	12	1	16966671	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	3489416	48489416	Rat
1331739	Hrtrt14	Heart rate QTL 14	3.56232		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	12	1	38687564	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2747694	47747694	Rat
2303568	Bw88	Body weight QTL 88	3		body mass (VT:0001259)	body weight (CMO:0000012)	12	1	28606299	Rat
61331	Eau2	Experimental allergic uveoretinitis QTL 2		0.0005	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	12	1	33700600	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	3087180	48087180	Rat
61334	Gluco17	Glucose level QTL 17	6.3		adipocyte glucose uptake trait (VT:0004185)	adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)	12	1	16966671	Rat
2293684	Bmd26	Bone mineral density QTL 26	4.4	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	12	1	38635130	Rat
6893681	Bw109	Body weight QTL 109	2.3	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	12	1	28133365	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	5633306	50633306	Rat
1300174	Bw15	Body weight QTL 15	2.93		body mass (VT:0001259)	body weight loss (CMO:0001399)	12	1	28606299	Rat
1600391	Edcs2	Endometrial carcinoma susceptibility QTL2	3.5	0.01	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	12	1	11869600	Rat
1331787	Rf41	Renal function QTL 41	2.998		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	12	1	33700556	Rat

Markers in Region

RH127969

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	1,682,314 - 1,682,530 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	2,173,034 - 2,173,249	NCBI	Rnor6.0
Rnor_5.0	12	4,335,366 - 4,335,581	UniSTS	Rnor5.0
RGSC_v3.4	12	2,530,835 - 2,531,050	UniSTS	RGSC3.4
Celera	12	3,538,091 - 3,538,306	UniSTS
Cytogenetic Map	12	p12	UniSTS

Pcp2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	1,681,755 - 1,682,967 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	2,172,475 - 2,173,686	NCBI	Rnor6.0
Rnor_5.0	12	4,334,807 - 4,336,018	UniSTS	Rnor5.0
RGSC_v3.4	12	2,530,398 - 2,531,609	UniSTS	RGSC3.4
Celera	12	3,537,532 - 3,538,743	UniSTS
Cytogenetic Map	12	p12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
7	8	13	82	41	39	14	34	14	6	104	65	64	11	40	25	12	12

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107116	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008768953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598311	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598312	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000001313 ⟹ ENSRNOP00000001313

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	6,479,554 - 6,481,307 (-)	Ensembl
mRatBN7.2 Ensembl	12	1,681,659 - 1,683,412 (-)	Ensembl
Rnor_6.0 Ensembl	12	2,172,378 - 2,174,131 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000106760 ⟹ ENSRNOP00000096666

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	6,479,871 - 6,481,794 (-)	Ensembl
mRatBN7.2 Ensembl	12	1,681,976 - 1,683,899 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000109866 ⟹ ENSRNOP00000083460

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	6,479,554 - 6,485,159 (-)	Ensembl
mRatBN7.2 Ensembl	12	1,681,659 - 1,683,364 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112638 ⟹ ENSRNOP00000080554

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	6,480,700 - 6,481,794 (-)	Ensembl
mRatBN7.2 Ensembl	12	1,682,805 - 1,683,899 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115359 ⟹ ENSRNOP00000078292

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	6,479,554 - 6,481,794 (-)	Ensembl
mRatBN7.2 Ensembl	12	1,681,659 - 1,683,899 (-)	Ensembl

RefSeq Acc Id:

NM_001107116 ⟹ NP_001100586

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	6,479,554 - 6,481,307 (-)	NCBI
mRatBN7.2	12	1,681,659 - 1,683,412 (-)	NCBI
Rnor_6.0	12	2,172,378 - 2,174,131 (-)	NCBI
Rnor_5.0	12	4,334,710 - 4,337,006 (-)	NCBI
RGSC_v3.4	12	2,529,953 - 2,531,706 (+)	RGD
Celera	12	3,537,435 - 3,539,188 (-)	RGD

Sequence:

show sequence

CATTTAGAGAAAATCTGCAGACCCGTGAGGACTATGGCAGGTTCACCTGACCAGGAAGGCTTCT
TCAACCTGCTGAGCCACGTGCAGGGCGATCGGATGGAGGAACAGCGCTGTTCCTTGCAAGCTGA
GCCAGGCCAGACCCCAGAAAGCCAGGGTGGCCCTGCTCCAGAGATGGACAACCTCATGGATATG
CTGGCCAACACCCAGGGCCGCCGCATGGATGACCAGCGTGTAACAGTCAATTCCCTGCCTGGCT
TCCAACCTATTGGTCCCAAGGATGGAATGCAGAAACGACCCGGGACACTCAGCCCTCAACCCCT
GCTCAGCCCGCAGGACCCTGCTGCTCTCAGCTTCCGCAGGAACAGTAGCCCCCAGCCCCAGACA
CAAGCTCCCTGAGAGTTCCAGCCACCCTGGGCCTCCCACTGGCCCCTGAAAGTAATAAAATACT
TGGCACTAGCGAC

hide sequence

RefSeq Acc Id:

XM_008768953 ⟹ XP_008767175

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	6,479,555 - 6,481,550 (-)	NCBI
mRatBN7.2	12	1,681,660 - 1,683,711 (-)	NCBI
Rnor_6.0	12	2,172,379 - 2,174,384 (-)	NCBI

Sequence:

show sequence

TGAATAGATTCTTAGTACTGTCCCCCAAGAGGTAGTAGGTGCTAGGATTTAGTGGGGTACTTCT
GAGCCCCATTTCCCTGGCAGGTTCACCTGACCAGGAAGGCTTCTTCAACCTGCTGAGCCACGTG
CAGGGCGATCGGATGGAGGAACAGCGCTGTTCCTTGCAAGCTGAGCCAGGCCAGACCCCAGAAA
GCCAGGGTGGCCCTGCTCCAGAGATGGACAACCTCATGGATATGCTGGCCAACACCCAGGGCCG
CCGCATGGATGACCAGCGTGTAACAGTCAATTCCCTGCCTGGCTTCCAACCTATTGGTCCCAAG
GATGGAATGCAGAAACGACCCGGGACACTCAGCCCTCAACCCCTGCTCAGCCCGCAGGACCCTG
CTGCTCTCAGCTTCCGCAGGAACAGTAGCCCCCAGCCCCAGACACAAGCTCCCTGAGAGTTCCA
GCCACCCTGGGCCTCCCACTGGCCCCTGAAAGTAATAAAATACTTGGCACTAGCGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001100586	(Get FASTA)	NCBI Sequence Viewer
	XP_008767175	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL74944	(Get FASTA)	NCBI Sequence Viewer
	EDL74945	(Get FASTA)	NCBI Sequence Viewer
	EDL74946	(Get FASTA)	NCBI Sequence Viewer
	EDL74947	(Get FASTA)	NCBI Sequence Viewer
	EDL74948	(Get FASTA)	NCBI Sequence Viewer
	EDL74949	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000001313
	ENSRNOP00000001313.5
	ENSRNOP00000078292.1
	ENSRNOP00000080554.1
	ENSRNOP00000083460.2
	ENSRNOP00000096666.1

RefSeq Acc Id:	NP_001100586 ⟸ NM_001107116
- UniProtKB:	D3ZXP8 (UniProtKB/TrEMBL), A6KQ19 (UniProtKB/TrEMBL), A0A8I5ZW35 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAGSPDQEGFFNLLSHVQGDRMEEQRCSLQAEPGQTPESQGGPAPEMDNLMDMLANTQGRRMDD QRVTVNSLPGFQPIGPKDGMQKRPGTLSPQPLLSPQDPAALSFRRNSSPQPQTQAP hide sequence

RefSeq Acc Id:	XP_008767175 ⟸ XM_008768953
- Peptide Label:	isoform X1
- UniProtKB:	A6KQ21 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEEQRCSLQAEPGQTPESQGGPAPEMDNLMDMLANTQGRRMDDQRVTVNSLPGFQPIGPKDGMQ KRPGTLSPQPLLSPQDPAALSFRRNSSPQPQTQAP hide sequence

Ensembl Acc Id:

ENSRNOP00000001313 ⟸ ENSRNOT00000001313

Ensembl Acc Id:

ENSRNOP00000096666 ⟸ ENSRNOT00000106760

Ensembl Acc Id:

ENSRNOP00000083460 ⟸ ENSRNOT00000109866

Ensembl Acc Id:

ENSRNOP00000078292 ⟸ ENSRNOT00000115359

Ensembl Acc Id:

ENSRNOP00000080554 ⟸ ENSRNOT00000112638

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZXP8-F1-model_v2	AlphaFold	D3ZXP8	1-120	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698372

Promoter ID:

EPDNEW_R8897

Type:

single initiation site

Name:

Pcp2_1

Description:

Purkinje cell protein 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	2,174,130 - 2,174,190	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306217	AgrOrtholog
BioCyc Gene	G2FUF-20391	BioCyc
Ensembl Genes	ENSRNOG00000000993	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000001313	ENTREZGENE
	ENSRNOT00000001313.7	UniProtKB/TrEMBL
	ENSRNOT00000106760.2	UniProtKB/TrEMBL
	ENSRNOT00000109866.2	UniProtKB/TrEMBL
	ENSRNOT00000112638.2	UniProtKB/TrEMBL
	ENSRNOT00000115359.2	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.10	UniProtKB/TrEMBL
InterPro	GoLoco_motif	UniProtKB/TrEMBL
	Pcp2	UniProtKB/TrEMBL
	TPR-like_helical_dom_sf	UniProtKB/TrEMBL
KEGG Report	rno:304195	UniProtKB/TrEMBL
NCBI Gene	304195	ENTREZGENE
PANTHER	PTHR47503	UniProtKB/TrEMBL
	PURKINJE CELL PROTEIN 2 HOMOLOG	UniProtKB/TrEMBL
Pfam	GoLoco	UniProtKB/TrEMBL
PhenoGen	Pcp2	PhenoGen
PROSITE	GOLOCO	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000000993	RatGTEx
SMART	GoLoco	UniProtKB/TrEMBL
UniProt	A0A8I5ZL58_RAT	UniProtKB/TrEMBL
	A0A8I5ZW35	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6APQ7_RAT	UniProtKB/TrEMBL
	A0A8I6G6S3_RAT	UniProtKB/TrEMBL
	A6KQ19	ENTREZGENE, UniProtKB/TrEMBL
	A6KQ21	ENTREZGENE, UniProtKB/TrEMBL
	A6KQ22_RAT	UniProtKB/TrEMBL
	A6KQ23_RAT	UniProtKB/TrEMBL
	A6KQ24_RAT	UniProtKB/TrEMBL
	D3ZXP8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-11-11	Pcp2	Purkinje cell protein 2	Pcp2	Purkinje cell protein 2 (L7)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Pcp2	Purkinje cell protein 2 (L7)	Pcp2_predicted	Purkinje cell protein 2 (L7) (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Pcp2_predicted	Purkinje cell protein 2 (L7) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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