Lrch3 (leucine rich repeats and calponin homology domain containing 3) - Rat Genome Database

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Gene: Lrch3 (leucine rich repeats and calponin homology domain containing 3) Rattus norvegicus
Analyze
Symbol: Lrch3
Name: leucine rich repeats and calponin homology domain containing 3
RGD ID: 1306200
Description: Predicted to be involved in septin cytoskeleton organization. Predicted to be located in membrane. Predicted to be active in cytosol. Orthologous to human LRCH3 (leucine rich repeats and calponin homology domain containing 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; gentamycin.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DISP complex protein LRCH3; leucine-rich repeat and calponin homology domain-containing protein 3; leucine-rich repeats and calponin homology (CH) domain containing 3; LOC303883
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81181,277,581 - 81,377,339 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1181,277,581 - 81,377,337 (-)EnsemblGRCr8
mRatBN7.21167,772,499 - 67,872,269 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1167,772,506 - 67,872,264 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1176,609,569 - 76,709,339 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01169,271,364 - 69,371,135 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01168,298,660 - 68,398,437 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01171,008,950 - 71,108,229 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,012,061 - 71,108,184 (-)Ensemblrn6Rnor6.0
Rnor_5.01174,093,857 - 74,193,105 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41169,619,236 - 69,692,162 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1167,216,909 - 67,315,953 (-)NCBICelera
RGSC_v3.11169,653,072 - 69,749,723 (-)NCBI
Cytogenetic Map11q22NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:29467281  


Genomics

Comparative Map Data
Lrch3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81181,277,581 - 81,377,339 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1181,277,581 - 81,377,337 (-)EnsemblGRCr8
mRatBN7.21167,772,499 - 67,872,269 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1167,772,506 - 67,872,264 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1176,609,569 - 76,709,339 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01169,271,364 - 69,371,135 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01168,298,660 - 68,398,437 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01171,008,950 - 71,108,229 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,012,061 - 71,108,184 (-)Ensemblrn6Rnor6.0
Rnor_5.01174,093,857 - 74,193,105 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41169,619,236 - 69,692,162 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1167,216,909 - 67,315,953 (-)NCBICelera
RGSC_v3.11169,653,072 - 69,749,723 (-)NCBI
Cytogenetic Map11q22NCBI
LRCH3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383197,791,226 - 197,888,436 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3197,791,226 - 197,888,436 (+)Ensemblhg38GRCh38
GRCh373197,518,097 - 197,615,307 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363199,002,542 - 199,082,853 (+)NCBIBuild 36Build 36hg18NCBI36
Build 343199,006,454 - 199,086,766NCBI
Celera3196,134,228 - 196,214,562 (+)NCBICelera
Cytogenetic Map3q29NCBI
HuRef3194,820,951 - 194,901,170 (+)NCBIHuRef
CHM1_13197,489,047 - 197,569,496 (+)NCBICHM1_1
T2T-CHM13v2.03200,523,608 - 200,620,895 (+)NCBIT2T-CHM13v2.0
Lrch3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391632,734,452 - 32,836,399 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1632,734,470 - 32,836,017 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381632,914,083 - 33,016,029 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1632,914,100 - 33,015,647 (+)Ensemblmm10GRCm38
MGSCv371632,914,186 - 33,016,115 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361632,833,847 - 32,935,776 (+)NCBIMGSCv36mm8
Celera1633,393,372 - 33,496,032 (+)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1623.46NCBI
Lrch3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542012,001,120 - 12,086,799 (-)Ensembl
ChiLan1.0NW_00495542011,998,567 - 12,086,872 (-)NCBIChiLan1.0ChiLan1.0
LRCH3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22195,700,958 - 195,808,735 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13195,707,603 - 195,835,180 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03195,208,347 - 195,311,200 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13205,090,246 - 205,177,047 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3205,090,281 - 205,189,348 (+)EnsemblpanPan2panpan1.1
LRCH3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13328,792,654 - 28,913,521 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3328,795,134 - 28,913,489 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3328,808,716 - 28,934,868 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03329,025,233 - 29,144,674 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3329,026,379 - 29,145,027 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13328,815,306 - 28,941,358 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03328,861,458 - 28,987,467 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03329,481,393 - 29,607,518 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Lrch3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602125,542,833 - 125,667,228 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936784221,305 - 341,327 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936784218,041 - 343,400 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRCH3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13134,406,080 - 134,539,326 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113134,406,077 - 134,539,363 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213144,000,039 - 144,133,962 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LRCH3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11591,505,534 - 91,602,261 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1591,505,483 - 91,601,769 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604165,451,355 - 65,566,900 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lrch3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473060,903,662 - 61,001,317 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473060,901,022 - 61,011,749 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Lrch3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1417,716,450 - 17,819,172 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Lrch3
1239 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:350
Count of miRNA genes:108
Interacting mature miRNAs:117
Transcripts:ENSRNOT00000051989, ENSRNOT00000063883, ENSRNOT00000073865
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)117330848796070872Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117961851999753367Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)115893182292356038Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)115775483796071021Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)116859932196497754Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat

Markers in Region
D11Got58  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21167,867,112 - 67,867,315 (+)MAPPERmRatBN7.2
Rnor_6.01171,103,077 - 71,103,279NCBIRnor6.0
Rnor_5.01174,187,983 - 74,188,185UniSTSRnor5.0
RGSC_v3.41169,687,021 - 69,687,224RGDRGSC3.4
RGSC_v3.41169,687,022 - 69,687,224UniSTSRGSC3.4
Celera1167,310,801 - 67,311,003UniSTS
RGSC_v3.11169,744,611 - 69,744,813RGD
RH 3.4 Map11387.7UniSTS
RH 3.4 Map11387.7RGD
RH 2.0 Map11258.3RGD
Cytogenetic Map11q22UniSTS
D7Got152  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21167,867,094 - 67,867,266 (+)MAPPERmRatBN7.2
Rnor_6.01171,103,059 - 71,103,230NCBIRnor6.0
Rnor_5.01174,187,965 - 74,188,136UniSTSRnor5.0
RGSC_v3.41169,687,003 - 69,687,175RGDRGSC3.4
RGSC_v3.41169,687,004 - 69,687,175UniSTSRGSC3.4
Celera1167,310,783 - 67,310,954UniSTS
RGSC_v3.11169,744,593 - 69,744,764RGD
RH 3.4 Map11375.73RGD
RH 3.4 Map11375.73UniSTS
Cytogenetic Map11q22UniSTS
D11Got116  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21167,839,205 - 67,839,323 (+)MAPPERmRatBN7.2
Rnor_6.01171,075,387 - 71,075,504NCBIRnor6.0
Rnor_5.01174,160,293 - 74,160,410UniSTSRnor5.0
RGSC_v3.41169,659,078 - 69,659,195UniSTSRGSC3.4
Celera1167,283,269 - 67,283,386UniSTS
Cytogenetic Map11q22UniSTS
RH144494  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81181,347,832 - 81,347,928 (+)Marker Load Pipeline
mRatBN7.21167,842,755 - 67,842,851 (+)MAPPERmRatBN7.2
Rnor_6.01171,078,937 - 71,079,032NCBIRnor6.0
Rnor_5.01174,163,843 - 74,163,938UniSTSRnor5.0
RGSC_v3.41169,662,627 - 69,662,722UniSTSRGSC3.4
Celera1167,286,819 - 67,286,914UniSTS
RH 3.4 Map11381.4UniSTS
Cytogenetic Map11q22UniSTS
RH138611  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21167,851,030 - 67,851,212 (+)MAPPERmRatBN7.2
Rnor_6.01171,086,999 - 71,087,180NCBIRnor6.0
Rnor_5.01174,171,905 - 74,172,086UniSTSRnor5.0
RGSC_v3.41169,670,944 - 69,671,125UniSTSRGSC3.4
Celera1167,294,758 - 67,294,939UniSTS
RH 3.4 Map11391.8UniSTS
Cytogenetic Map11q22UniSTS
RH138987  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21167,869,856 - 67,870,010 (+)MAPPERmRatBN7.2
Rnor_6.01171,105,821 - 71,105,974NCBIRnor6.0
Rnor_5.01174,190,727 - 74,190,880UniSTSRnor5.0
RGSC_v3.41169,689,766 - 69,689,919UniSTSRGSC3.4
Celera1167,313,545 - 67,313,698UniSTS
RH 3.4 Map11391.8UniSTS
Cytogenetic Map11q22UniSTS
RH139375  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21167,878,082 - 67,878,184 (+)MAPPERmRatBN7.2
Rnor_6.01171,114,047 - 71,114,148NCBIRnor6.0
Rnor_5.01174,198,953 - 74,199,054UniSTSRnor5.0
RGSC_v3.41169,697,992 - 69,698,093UniSTSRGSC3.4
Celera1167,321,771 - 67,321,872UniSTS
RH 3.4 Map11393.1UniSTS
Cytogenetic Map11q22UniSTS
RH141328  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21167,853,405 - 67,853,585 (+)MAPPERmRatBN7.2
Rnor_6.01171,089,374 - 71,089,553NCBIRnor6.0
Rnor_5.01174,174,280 - 74,174,459UniSTSRnor5.0
RGSC_v3.41169,673,319 - 69,673,498UniSTSRGSC3.4
Celera1167,297,133 - 67,297,312UniSTS
RH 3.4 Map11391.9UniSTS
Cytogenetic Map11q22UniSTS
RH141635  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21167,841,161 - 67,841,366 (+)MAPPERmRatBN7.2
Rnor_6.01171,077,343 - 71,077,547NCBIRnor6.0
Rnor_5.01174,162,249 - 74,162,453UniSTSRnor5.0
RGSC_v3.41169,661,033 - 69,661,237UniSTSRGSC3.4
Celera1167,285,225 - 67,285,429UniSTS
RH 3.4 Map11390.6UniSTS
Cytogenetic Map11q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001371837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001371838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003751063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003752499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003752500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003752501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BQ205192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000051989   ⟹   ENSRNOP00000042417
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1181,277,581 - 81,377,337 (-)Ensembl
mRatBN7.2 Ensembl1167,774,286 - 67,872,229 (-)Ensembl
Rnor_6.0 Ensembl1171,012,061 - 71,108,184 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000063883   ⟹   ENSRNOP00000063876
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1181,282,875 - 81,377,337 (-)Ensembl
mRatBN7.2 Ensembl1167,776,498 - 67,872,264 (-)Ensembl
Rnor_6.0 Ensembl1171,012,061 - 71,108,184 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000073865   ⟹   ENSRNOP00000066301
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1181,291,228 - 81,377,337 (-)Ensembl
mRatBN7.2 Ensembl1167,776,498 - 67,872,264 (-)Ensembl
Rnor_6.0 Ensembl1171,012,061 - 71,108,184 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094874   ⟹   ENSRNOP00000097753
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1181,277,581 - 81,377,293 (-)Ensembl
mRatBN7.2 Ensembl1167,772,506 - 67,872,220 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096046   ⟹   ENSRNOP00000077497
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1181,277,581 - 81,377,337 (-)Ensembl
mRatBN7.2 Ensembl1167,772,506 - 67,872,264 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096328   ⟹   ENSRNOP00000092260
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1181,277,581 - 81,377,337 (-)Ensembl
mRatBN7.2 Ensembl1167,772,506 - 67,872,264 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116720   ⟹   ENSRNOP00000097063
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1181,277,581 - 81,377,337 (-)Ensembl
mRatBN7.2 Ensembl1167,772,506 - 67,872,264 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000137113   ⟹   ENSRNOP00000103234
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1181,277,581 - 81,377,337 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000156474   ⟹   ENSRNOP00000106132
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1181,277,581 - 81,377,337 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000158083   ⟹   ENSRNOP00000112526
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1181,277,581 - 81,377,337 (-)Ensembl
RefSeq Acc Id: NM_001371837   ⟹   NP_001358766
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,277,581 - 81,377,337 (-)NCBI
mRatBN7.21167,772,500 - 67,872,264 (-)NCBI
RefSeq Acc Id: NM_001371838   ⟹   NP_001358767
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,277,581 - 81,377,337 (-)NCBI
mRatBN7.21167,772,500 - 67,872,264 (-)NCBI
RefSeq Acc Id: XM_039088324   ⟹   XP_038944252
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,280,989 - 81,377,339 (-)NCBI
mRatBN7.21167,775,908 - 67,872,269 (-)NCBI
RefSeq Acc Id: XM_039088325   ⟹   XP_038944253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,280,989 - 81,377,339 (-)NCBI
mRatBN7.21167,775,908 - 67,872,269 (-)NCBI
RefSeq Acc Id: XM_039088326   ⟹   XP_038944254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,280,989 - 81,377,339 (-)NCBI
mRatBN7.21167,775,908 - 67,872,269 (-)NCBI
RefSeq Acc Id: XM_039088328   ⟹   XP_038944256
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,280,989 - 81,377,339 (-)NCBI
mRatBN7.21167,775,908 - 67,872,269 (-)NCBI
RefSeq Acc Id: XM_039088329   ⟹   XP_038944257
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,280,989 - 81,377,339 (-)NCBI
mRatBN7.21167,775,908 - 67,872,269 (-)NCBI
RefSeq Acc Id: XM_039088330   ⟹   XP_038944258
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,280,989 - 81,377,338 (-)NCBI
mRatBN7.21167,775,908 - 67,872,269 (-)NCBI
RefSeq Acc Id: XM_039088332   ⟹   XP_038944260
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,280,989 - 81,377,339 (-)NCBI
mRatBN7.21167,775,908 - 67,872,269 (-)NCBI
RefSeq Acc Id: XM_039088334   ⟹   XP_038944262
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,280,989 - 81,377,338 (-)NCBI
mRatBN7.21167,775,908 - 67,872,269 (-)NCBI
RefSeq Acc Id: XM_039088335   ⟹   XP_038944263
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,280,989 - 81,377,338 (-)NCBI
mRatBN7.21167,775,908 - 67,872,269 (-)NCBI
RefSeq Acc Id: XM_039088336   ⟹   XP_038944264
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,277,581 - 81,377,338 (-)NCBI
mRatBN7.21167,772,499 - 67,872,268 (-)NCBI
RefSeq Acc Id: XM_039088337   ⟹   XP_038944265
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,280,989 - 81,377,339 (-)NCBI
mRatBN7.21167,775,908 - 67,872,269 (-)NCBI
RefSeq Acc Id: XM_063270506   ⟹   XP_063126576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,277,581 - 81,377,338 (-)NCBI
RefSeq Acc Id: XM_063270507   ⟹   XP_063126577
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,280,989 - 81,377,339 (-)NCBI
RefSeq Acc Id: XM_063270508   ⟹   XP_063126578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,277,581 - 81,377,338 (-)NCBI
RefSeq Acc Id: XM_063270509   ⟹   XP_063126579
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,277,581 - 81,377,338 (-)NCBI
RefSeq Acc Id: XM_063270510   ⟹   XP_063126580
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,277,581 - 81,377,338 (-)NCBI
RefSeq Acc Id: XM_063270511   ⟹   XP_063126581
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,277,581 - 81,377,338 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001358766 (Get FASTA)   NCBI Sequence Viewer  
  NP_001358767 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944252 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944253 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944254 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944256 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944257 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944258 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944260 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944262 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944263 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944264 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944265 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126576 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126577 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126578 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126579 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126580 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126581 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM11382 (Get FASTA)   NCBI Sequence Viewer  
  EDM11383 (Get FASTA)   NCBI Sequence Viewer  
  EDM11384 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000042417
  ENSRNOP00000042417.6
  ENSRNOP00000063876
  ENSRNOP00000063876.4
  ENSRNOP00000066301.3
  ENSRNOP00000077497
  ENSRNOP00000077497.1
  ENSRNOP00000092260
  ENSRNOP00000092260.1
  ENSRNOP00000097063
  ENSRNOP00000097063.1
  ENSRNOP00000097753.1
  ENSRNOP00000103234
  ENSRNOP00000103234.1
  ENSRNOP00000106132.1
  ENSRNOP00000112526.1
Ensembl Acc Id: ENSRNOP00000063876   ⟸   ENSRNOT00000063883
Ensembl Acc Id: ENSRNOP00000042417   ⟸   ENSRNOT00000051989
Ensembl Acc Id: ENSRNOP00000066301   ⟸   ENSRNOT00000073865
RefSeq Acc Id: XP_038944264   ⟸   XM_039088336
- Peptide Label: isoform X16
- UniProtKB: A0A8I6AN41 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001358767   ⟸   NM_001371838
- Peptide Label: 2
- UniProtKB: A0A8I6AH73 (UniProtKB/TrEMBL),   A0A8I6AN41 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001358766   ⟸   NM_001371837
- Peptide Label: 1
- UniProtKB: A0A8I5ZJI0 (UniProtKB/TrEMBL),   A6IRN0 (UniProtKB/TrEMBL),   A0A8I6AN41 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944265   ⟸   XM_039088337
- Peptide Label: isoform X17
- UniProtKB: A0A8I6AN41 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944263   ⟸   XM_039088335
- Peptide Label: isoform X13
- UniProtKB: A0A8I6AN41 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944262   ⟸   XM_039088334
- Peptide Label: isoform X9
- UniProtKB: A0A8I6AN41 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944258   ⟸   XM_039088330
- Peptide Label: isoform X7
- UniProtKB: D3ZWD1 (UniProtKB/TrEMBL),   A0A8I6AN41 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944256   ⟸   XM_039088328
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AN41 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944253   ⟸   XM_039088325
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AN41 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944260   ⟸   XM_039088332
- Peptide Label: isoform X8
- UniProtKB: A0A8I6AN41 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944254   ⟸   XM_039088326
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AN41 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944257   ⟸   XM_039088329
- Peptide Label: isoform X5
- UniProtKB: A0A8I6AN41 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944252   ⟸   XM_039088324
- Peptide Label: isoform X1
- UniProtKB: M0R9W9 (UniProtKB/TrEMBL),   A0A8I6AN41 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000077497   ⟸   ENSRNOT00000096046
Ensembl Acc Id: ENSRNOP00000097753   ⟸   ENSRNOT00000094874
Ensembl Acc Id: ENSRNOP00000092260   ⟸   ENSRNOT00000096328
Ensembl Acc Id: ENSRNOP00000097063   ⟸   ENSRNOT00000116720
RefSeq Acc Id: XP_063126581   ⟸   XM_063270511
- Peptide Label: isoform X15
- UniProtKB: A0A8I6AN41 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126580   ⟸   XM_063270510
- Peptide Label: isoform X14
- UniProtKB: D4A8M4 (UniProtKB/TrEMBL),   A0A8I6AN41 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126578   ⟸   XM_063270508
- Peptide Label: isoform X11
- UniProtKB: A6IRM9 (UniProtKB/TrEMBL),   A0A8I6AN41 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126579   ⟸   XM_063270509
- Peptide Label: isoform X12
- UniProtKB: A0A8I6AN41 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126576   ⟸   XM_063270506
- Peptide Label: isoform X6
- UniProtKB: A0A8I6AN41 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126577   ⟸   XM_063270507
- Peptide Label: isoform X10
- UniProtKB: A0A8I6AN41 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000103234   ⟸   ENSRNOT00000137113
Ensembl Acc Id: ENSRNOP00000112526   ⟸   ENSRNOT00000158083
Ensembl Acc Id: ENSRNOP00000106132   ⟸   ENSRNOT00000156474
Protein Domains
Calponin-homology (CH)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A8M4-F1-model_v2 AlphaFold D4A8M4 1-769 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698207
Promoter ID:EPDNEW_R8729
Type:multiple initiation site
Name:Lrch3_1
Description:leucine rich repeats and calponin homology domain containing3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01171,108,204 - 71,108,264EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306200 AgrOrtholog
BioCyc Gene G2FUF-21119 BioCyc
Ensembl Genes ENSRNOG00000001774 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000051989 ENTREZGENE
  ENSRNOT00000051989.8 UniProtKB/TrEMBL
  ENSRNOT00000063883 ENTREZGENE
  ENSRNOT00000063883.4 UniProtKB/TrEMBL
  ENSRNOT00000073865.5 UniProtKB/TrEMBL
  ENSRNOT00000094874.2 UniProtKB/TrEMBL
  ENSRNOT00000096046 ENTREZGENE
  ENSRNOT00000096046.2 UniProtKB/TrEMBL
  ENSRNOT00000096328 ENTREZGENE
  ENSRNOT00000096328.2 UniProtKB/TrEMBL
  ENSRNOT00000116720 ENTREZGENE
  ENSRNOT00000116720.2 UniProtKB/TrEMBL
  ENSRNOT00000137113 ENTREZGENE
  ENSRNOT00000137113.1 UniProtKB/TrEMBL
  ENSRNOT00000156474.1 UniProtKB/TrEMBL
  ENSRNOT00000158083.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro Calponin-like_dom_sf UniProtKB/TrEMBL
  CH-domain UniProtKB/TrEMBL
  L_dom-like UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_domain-containing UniProtKB/TrEMBL
NCBI Gene 303883 ENTREZGENE
PANTHER LEUCINE RICH REPEATS AND CALPONIN HOMOLOGY DOMAIN CONTAINING 3 UniProtKB/TrEMBL
  PTHR48051 UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
  PF00307 UniProtKB/TrEMBL
PhenoGen Lrch3 PhenoGen
PROSITE PS50021 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001774 RatGTEx
SMART LRR_BAC UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  SM00033 UniProtKB/TrEMBL
Superfamily-SCOP Calponin-homology UniProtKB/TrEMBL
  L domain-like UniProtKB/TrEMBL
UniProt A0A8I5ZJI0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AH73 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AN41 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6B669_RAT UniProtKB/TrEMBL
  A0ABK0LCS7_RAT UniProtKB/TrEMBL
  A0ABK0LSC1_RAT UniProtKB/TrEMBL
  A0ABK0M0X2_RAT UniProtKB/TrEMBL
  A6IRM9 ENTREZGENE, UniProtKB/TrEMBL
  A6IRN0 ENTREZGENE, UniProtKB/TrEMBL
  D3ZWD1 ENTREZGENE, UniProtKB/TrEMBL
  D4A8M4 ENTREZGENE, UniProtKB/TrEMBL
  M0R9W9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-15 Lrch3  leucine rich repeats and calponin homology domain containing 3  Lrch3  leucine-rich repeats and calponin homology (CH) domain containing 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Lrch3  leucine-rich repeats and calponin homology (CH) domain containing 3   Lrch3_predicted  leucine-rich repeats and calponin homology (CH) domain containing 3 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Lrch3_predicted  leucine-rich repeats and calponin homology (CH) domain containing 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED