Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Ly6d (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of LY6D mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of LY6D mRNA | CTD | PMID:22206623 | 17beta-estradiol | decreases expression | ISO | LY6D (Homo sapiens) | 6480464 | Estradiol results in decreased expression of LY6D mRNA | CTD | PMID:31614463 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Ly6d (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LY6D mRNA | CTD | PMID:17035482 and PMID:21041162 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ly6d (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of LY6D mRNA | CTD | PMID:21570461 and PMID:26377647 | 2-acetamidofluorene | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | 2-Acetylaminofluorene results in increased expression of LY6D mRNA | CTD | PMID:17317680 | 4,4'-diaminodiphenylmethane | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of LY6D mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | bisphenol S results in increased expression of LY6D mRNA | CTD | PMID:30951980 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of LY6D mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of LY6D mRNA | CTD | PMID:19770486 | aflatoxin B1 | increases expression | ISO | LY6D (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of LY6D mRNA | CTD | PMID:21641981 | all-trans-retinoic acid | decreases expression | ISO | LY6D (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of LY6D mRNA | CTD | PMID:23830798 | amiodarone | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Amiodarone results in increased expression of LY6D mRNA | CTD | PMID:24489787 | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of LY6D mRNA | CTD | PMID:30779732 | arsane | affects methylation | ISO | LY6D (Homo sapiens) | 6480464 | Arsenic affects the methylation of LY6D gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | LY6D (Homo sapiens) | 6480464 | Arsenic affects the methylation of LY6D gene | CTD | PMID:25304211 | benzo[a]pyrene | increases expression | ISO | LY6D (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of LY6D mRNA | CTD | PMID:22316170 and PMID:32234424 | benzo[a]pyrene | affects methylation | ISO | LY6D (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of LY6D promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | LY6D (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of LY6D exon | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | Ly6d (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of LY6D mRNA | CTD | PMID:21569818 and PMID:22610609 | bezafibrate | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Bezafibrate results in increased expression of LY6D mRNA | CTD | PMID:17118139 | bis(2-ethylhexyl) phthalate | increases expression | ISO | LY6D (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of LY6D mRNA | CTD | PMID:28412506 | bisphenol A | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | bisphenol A results in increased expression of LY6D mRNA | CTD | PMID:20739668 and PMID:32156529 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of LY6D mRNA | CTD | PMID:25181051 | cadmium dichloride | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Cadmium Chloride results in increased expression of LY6D mRNA | CTD | PMID:24982889 | cannabidiol | decreases expression | ISO | LY6D (Homo sapiens) | 6480464 | Cannabidiol results in decreased expression of LY6D mRNA | CTD | PMID:33244087 | cantharidin | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Cantharidin results in increased expression of LY6D mRNA | CTD | PMID:36907384 | carbon nanotube | affects expression | ISO | Ly6d (Mus musculus) | 6480464 | Nanotubes and Carbon affects the expression of LY6D mRNA | CTD | PMID:25554681 | carbon nanotube | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | carbon nanotube | decreases expression | ISO | Ly6d (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of LY6D mRNA | CTD | PMID:25554681 | chlordecone | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Chlordecone results in increased expression of LY6D mRNA | CTD | PMID:33711761 | chloroprene | decreases expression | ISO | Ly6d (Mus musculus) | 6480464 | Chloroprene results in decreased expression of LY6D mRNA | CTD | PMID:23125180 | choline | multiple interactions | ISO | Ly6d (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of LY6D mRNA | CTD | PMID:20938992 | chromium(3+) trichloride | decreases expression | ISO | Ly6d (Mus musculus) | 6480464 | chromic chloride results in decreased expression of LY6D mRNA | CTD | PMID:12128095 | ciprofibrate | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | ciprofibrate results in increased expression of LY6D mRNA | CTD | PMID:12771043 | clofibrate | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Clofibrate results in increased expression of LY6D mRNA | CTD | PMID:23811191 | dexamethasone | decreases expression | ISO | Ly6d (Mus musculus) | 6480464 | Dexamethasone results in decreased expression of LY6D mRNA | CTD | PMID:21041162 | dextran sulfate | decreases expression | ISO | Ly6d (Mus musculus) | 6480464 | Dextran Sulfate results in decreased expression of LY6D mRNA | CTD | PMID:35093514 | diazinon | increases methylation | ISO | LY6D (Homo sapiens) | 6480464 | Diazinon results in increased methylation of LY6D gene | CTD | PMID:22964155 | dichloroacetic acid | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Dichloroacetic Acid results in increased expression of LY6D mRNA | CTD | PMID:28962523 | diethylstilbestrol | decreases expression | ISO | Ly6d (Mus musculus) | 6480464 | Diethylstilbestrol results in decreased expression of LY6D mRNA | CTD | PMID:21041162 | dimethylarsinic acid | multiple interactions | ISO | Ly6d (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of LY6D mRNA | CTD | PMID:34876320 | enilconazole | decreases expression | ISO | LY6D (Homo sapiens) | 6480464 | enilconazole results in decreased expression of LY6D mRNA | CTD | PMID:32201337 | epoxiconazole | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | epoxiconazole results in increased expression of LY6D mRNA | CTD | PMID:35436446 | fenofibrate | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Fenofibrate results in increased expression of LY6D mRNA | CTD | PMID:17118139 | folic acid | multiple interactions | ISO | Ly6d (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of LY6D mRNA | CTD | PMID:20938992 | furan | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | furan results in increased expression of LY6D mRNA | CTD | PMID:24183702 | genistein | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Genistein results in increased expression of LY6D mRNA | CTD | PMID:22553218 and PMID:32186404 | griseofulvin | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Griseofulvin results in increased expression of LY6D mRNA | CTD | PMID:12735108 | L-methionine | multiple interactions | ISO | Ly6d (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of LY6D mRNA | CTD | PMID:20938992 | lead(0) | affects methylation | ISO | LY6D (Homo sapiens) | 6480464 | Lead affects the methylation of LY6D gene | CTD | PMID:31636367 | methotrexate | affects expression | ISO | Ly6d (Mus musculus) | 6480464 | Methotrexate affects the expression of LY6D mRNA | CTD | PMID:18502557 | methylarsonic acid | multiple interactions | ISO | Ly6d (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of LY6D mRNA | CTD | PMID:34876320 | N-nitrosodiethylamine | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Diethylnitrosamine results in increased expression of LY6D mRNA | CTD | PMID:12771043 and PMID:24535843 | N-nitrosodiethylamine | multiple interactions | ISO | Ly6d (Mus musculus) | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of LY6D mRNA | CTD | PMID:24535843 | nickel atom | increases expression | ISO | LY6D (Homo sapiens) | 6480464 | Nickel results in increased expression of LY6D mRNA | CTD | PMID:25583101 | ozone | decreases expression | ISO | Ly6d (Mus musculus) | 6480464 | Ozone results in decreased expression of LY6D mRNA | CTD | PMID:17095637 | ozone | multiple interactions | ISO | Ly6d (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of LY6D mRNA | CTD | PMID:34911549 | paracetamol | affects expression | ISO | Ly6d (Mus musculus) | 6480464 | Acetaminophen affects the expression of LY6D mRNA | CTD | PMID:17562736 | paracetamol | multiple interactions | ISO | Ly6d (Mus musculus) | 6480464 | PANX1 gene mutant form inhibits the reaction [Acetaminophen results in increased expression of LY6D mRNA] | CTD | PMID:29246445 | paracetamol | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Acetaminophen results in increased expression of LY6D mRNA | CTD | PMID:29246445 | paracetamol | increases expression | ISO | LY6D (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of LY6D mRNA | CTD | PMID:22230336 | perfluorohexanesulfonic acid | decreases expression | ISO | Ly6d (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of LY6D mRNA | CTD | PMID:37995155 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Ly6d (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of LY6D mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of LY6D mRNA | CTD | PMID:36331819 | phenobarbital | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Phenobarbital results in increased expression of LY6D mRNA | CTD | PMID:19482888 | phenobarbital | multiple interactions | ISO | Ly6d (Mus musculus) | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of LY6D mRNA and NR1I3 protein affects the reaction [Phenobarbital results in increased expression of LY6D mRNA] | CTD | PMID:19482888 and PMID:24535843 | pirinixic acid | multiple interactions | ISO | Ly6d (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of LY6D mRNA | CTD | PMID:19710929 | pirinixic acid | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | pirinixic acid results in increased expression of LY6D mRNA | CTD | PMID:17118139 more ... | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Ly6d (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of LY6D mRNA | CTD | PMID:22698814 | prochloraz | increases expression | EXP | | 6480464 | prochloraz results in increased expression of LY6D mRNA | CTD | PMID:29038839 | propanal | increases expression | ISO | LY6D (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of LY6D mRNA | CTD | PMID:26079696 | resveratrol | multiple interactions | ISO | Ly6d (Mus musculus) | 6480464 | resveratrol inhibits the reaction [Dietary Fats affects the expression of LY6D mRNA] | CTD | PMID:17086191 | resveratrol | multiple interactions | ISO | LY6D (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of LY6D mRNA | CTD | PMID:23557933 | sodium arsenate | multiple interactions | ISO | Ly6d (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of LY6D mRNA | CTD | PMID:34876320 | sodium arsenite | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | sodium arsenite results in increased expression of LY6D mRNA | CTD | PMID:17350061 | sodium arsenite | decreases expression | ISO | Ly6d (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of LY6D mRNA | CTD | PMID:33933676 and PMID:37682722 | sodium arsenite | multiple interactions | ISO | Ly6d (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of LY6D mRNA | CTD | PMID:34876320 | sodium arsenite | increases expression | ISO | LY6D (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of LY6D mRNA | CTD | PMID:34032870 | tetrachloromethane | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of LY6D mRNA | CTD | PMID:27339419 more ... | titanium dioxide | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | titanium dioxide results in increased expression of LY6D mRNA | CTD | PMID:23409001 and PMID:23557971 | titanium dioxide | decreases expression | ISO | Ly6d (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of LY6D mRNA | CTD | PMID:27760801 | tributylstannane | decreases expression | ISO | Ly6d (Mus musculus) | 6480464 | tributyltin results in decreased expression of LY6D mRNA | CTD | PMID:31939706 | trichloroethene | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Trichloroethylene results in increased expression of LY6D mRNA | CTD | PMID:25549359 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of LY6D mRNA | CTD | PMID:33387578 | urethane | decreases expression | ISO | LY6D (Homo sapiens) | 6480464 | Urethane results in decreased expression of LY6D mRNA | CTD | PMID:28818685 | valproic acid | increases methylation | ISO | LY6D (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of LY6D gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | Ly6d (Mus musculus) | 6480464 | Valproic Acid affects the expression of LY6D mRNA | CTD | PMID:17292431 | valproic acid | increases expression | ISO | Ly6d (Mus musculus) | 6480464 | Valproic Acid results in increased expression of LY6D mRNA | CTD | PMID:24489787 | |