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Gene: Ssh1 (slingshot protein phosphatase 1) Rattus norvegicus

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Symbol:

Ssh1

Name:

slingshot protein phosphatase 1

RGD ID:

1306038

Description:

Predicted to enable actin binding activity and phosphoprotein phosphatase activity. Involved in several processes, including excitatory chemical synaptic transmission; modulation of chemical synaptic transmission; and positive regulation of AMPA glutamate receptor clustering. Located in cell leading edge and growth cone. Orthologous to human SSH1 (slingshot protein phosphatase 1); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; fibroblast growth factor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC304580; protein phosphatase Slingshot homolog 1; slingshot 1; slingshot homolog 1; slingshot homolog 1 (Drosophila)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SSH1 (slingshot protein phosphatase 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Ssh1 (slingshot protein phosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ssh1 (slingshot protein phosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SSH1 (slingshot protein phosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SSH1 (slingshot protein phosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ssh1 (slingshot protein phosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SSH1 (slingshot protein phosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SSH1 (slingshot protein phosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ssh1 (slingshot protein phosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ssh1 (slingshot protein phosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SSH1 (slingshot protein phosphatase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ssh1 (slingshot protein phosphatase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ssh1b (slingshot protein phosphatase 1b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ssh1b (slingshot protein phosphatase 1b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	ssh1a (slingshot protein phosphatase 1a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SDP1	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PhylomeDB)
Drosophila melanogaster (fruit fly):	ssh	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ssh1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	48,281,756 - 48,343,812 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	48,281,756 - 48,343,812 (+)	Ensembl				GRCr8
mRatBN7.2	12	42,621,127 - 42,683,262 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	42,621,135 - 42,683,274 (+)	Ensembl				mRatBN7.2
Rnor_6.0	12	48,403,184 - 48,447,964 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	48,403,797 - 48,446,977 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	50,186,534 - 50,230,469 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	43,660,409 - 43,714,743 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	44,244,046 - 44,282,157 (+)	NCBI		Celera
RGSC_v3.1	12	43,510,743 - 43,575,432 (+)	NCBI
Cytogenetic Map	12	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Neointima (IEP)

primary ovarian insufficiency (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

17beta-estradiol (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

amitrole (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

beta-naphthoflavone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

calcitriol (ISO)

carbamazepine (ISO)

CGP 52608 (ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

dicrotophos (ISO)

doxorubicin (ISO)

endosulfan (ISO)

ethyl methanesulfonate (ISO)

FR900359 (ISO)

lead(0) (ISO)

methimazole (EXP)

methoxychlor (EXP)

methylmercury chloride (ISO)

nickel atom (ISO)

paracetamol (EXP,ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

raloxifene (ISO)

Rutecarpine (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

tamoxifen (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

triphenyl phosphate (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin cytoskeleton organization (IBA,IEA,ISO)

cell morphogenesis (IEA,ISO)

cellular response to ATP (ISO)

excitatory chemical synaptic transmission (IMP)

negative regulation of actin filament polymerization (IBA,IEA)

positive regulation of AMPA glutamate receptor clustering (IMP)

positive regulation of cellular process (IMP)

positive regulation of excitatory postsynaptic potential (IMP)

positive regulation of synaptic plasticity (IMP)

positive regulation of vascular associated smooth muscle cell migration (IMP)

protein dephosphorylation (ISO)

regulation of protein metabolic process (ISO)

Cellular Component

cell leading edge (IDA)

cell projection (IDA)

cleavage furrow (IEA)

cytoplasm (IBA,IEA,ISO)

cytoskeleton (IEA)

growth cone (IDA)

midbody (IEA)

plasma membrane (IEA,ISO)

synapse (IEA)

Molecular Function

actin binding (IBA,IEA,ISO)

hydrolase activity (IEA)

phosphatase activity (IEA)

phosphoprotein phosphatase activity (IBA,IEA,ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

fibroblast growth factor signaling pathway (ISO)

insulin responsive facilitative sugar transporter mediated glucose transport pathway (IMP)

Rab family mediated signaling pathway (IMP)

References

References - curated

#	Reference Title	Reference Citation
1.	Arp2/3- and cofilin-coordinated actin dynamics is required for insulin-mediated GLUT4 translocation to the surface of muscle cells.	Chiu TT, etal., Mol Biol Cell. 2010 Oct 15;21(20):3529-39. doi: 10.1091/mbc.E10-04-0316. Epub 2010 Aug 25.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
6.	Cofilin activation mediates Bax translocation to mitochondria during excitotoxic neuronal death.	Posadas I, etal., J Neurochem. 2012 Feb;120(4):515-27. doi: 10.1111/j.1471-4159.2011.07599.x.
7.	GOA pipeline	RGD automated data pipeline
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Comprehensive gene review and curation	RGD comprehensive gene curation
10.	Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin.	Soosairajah J, etal., EMBO J. 2005 Feb 9;24(3):473-86. Epub 2005 Jan 20.
11.	The actin-severing protein cofilin is downstream of neuregulin signaling and is essential for Schwann cell myelination.	Sparrow N, etal., J Neurosci. 2012 Apr 11;32(15):5284-97. doi: 10.1523/JNEUROSCI.6207-11.2012.
12.	Slingshot isoform-specific regulation of cofilin-mediated vascular smooth muscle cell migration and neointima formation.	Torres RA, etal., Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2424-31. doi: 10.1161/ATVBAHA.111.232769.
13.	Regulation of AMPA receptor channels and synaptic plasticity by cofilin phosphatase Slingshot in cortical neurons.	Yuen EY, etal., J Physiol. 2010 Jul 1;588(Pt 13):2361-71. doi: 10.1113/jphysiol.2009.186353. Epub 2010 May 4.

Additional References at PubMed

PMID:11832213	PMID:14645219	PMID:19000834

Genomics

Comparative Map Data

Ssh1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	48,281,756 - 48,343,812 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	48,281,756 - 48,343,812 (+)	Ensembl				GRCr8
mRatBN7.2	12	42,621,127 - 42,683,262 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	42,621,135 - 42,683,274 (+)	Ensembl				mRatBN7.2
Rnor_6.0	12	48,403,184 - 48,447,964 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	48,403,797 - 48,446,977 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	50,186,534 - 50,230,469 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	43,660,409 - 43,714,743 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	44,244,046 - 44,282,157 (+)	NCBI		Celera
RGSC_v3.1	12	43,510,743 - 43,575,432 (+)	NCBI
Cytogenetic Map	12	q16	NCBI

SSH1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	108,778,191 - 108,857,583 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	108,778,191 - 108,857,613 (-)	Ensembl			hg38	GRCh38
GRCh37	12	109,171,967 - 109,251,359 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	107,705,099 - 107,775,480 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	107,683,435 - 107,753,817	NCBI
Celera	12	108,845,298 - 108,920,242 (-)	NCBI		Celera
Cytogenetic Map	12	q24.11	NCBI
HuRef	12	106,241,529 - 106,316,009 (-)	NCBI		HuRef
CHM1_1	12	109,144,150 - 109,219,118 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	108,752,810 - 108,832,275 (-)	NCBI		T2T-CHM13v2.0

Ssh1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	114,075,155 - 114,131,864 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	114,075,155 - 114,131,955 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	113,937,094 - 113,993,803 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	113,937,094 - 113,993,894 (-)	Ensembl			mm10	GRCm38
MGSCv37	5	114,392,228 - 114,443,766 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	114,203,218 - 114,254,755 (-)	NCBI		MGSCv36	mm8
Celera	5	111,045,062 - 111,096,571 (-)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	55.82	NCBI

Ssh1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955455	10,020,465 - 10,053,476 (-)	Ensembl
ChiLan1.0	NW_004955455	10,019,992 - 10,077,485 (-)	NCBI	ChiLan1.0	ChiLan1.0

SSH1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	116,846,321 - 116,921,476 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	116,842,719 - 116,917,868 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	106,357,147 - 106,432,295 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	109,753,103 - 109,823,442 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	109,758,399 - 109,823,444 (-)	Ensembl			panPan2	panpan1.1

SSH1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	18,074,229 - 18,136,001 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	18,074,075 - 18,131,185 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	17,665,996 - 17,727,738 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	18,418,071 - 18,479,821 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	18,417,662 - 18,479,652 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	17,875,377 - 17,937,286 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	18,408,967 - 18,470,721 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	18,427,702 - 18,489,499 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ssh1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	144,755,039 - 144,815,370 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936769	669,793 - 697,893 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936769	665,146 - 721,131 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SSH1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	41,968,466 - 42,025,726 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	41,963,946 - 42,030,842 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	44,506,881 - 44,573,822 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SSH1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	103,982,889 - 104,059,673 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666037	141,038,724 - 141,114,755 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ssh1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	12,019,702 - 12,081,354 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624747	12,017,371 - 12,081,452 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ssh1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	16	39,965,375 - 40,021,875 (+)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	210
Count of miRNA genes:	90
Interacting mature miRNAs:	92
Transcripts:	ENSRNOT00000000883, ENSRNOT00000044751
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	24805022	52308831	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	11200494	52308831	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
8693635	Alc28	Alcohol consumption QTL 28	2.7	0.439	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	50386405	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	25989355	52308831	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	3489416	48489416	Rat
1300162	Bp188	Blood pressure QTL 188	3.19		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	37764145	51558799	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	18473041	52308831	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	15264248	52308831	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200497	52308831	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	11743528	52308831	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
1300175	Cm5	Cardiac mass QTL 5	3.78		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	33700432	51558799	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	16187438	52308831	Rat
8693658	Alc33	Alcohol consumption QTL 33	2.1	0.68	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	49212240	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	16135029	52308831	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	51213550	Rat
1331763	Wbc2	White blood cell count QTL 2	3.162		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	12	11200494	52308831	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	11200494	52308831	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	18473041	52308831	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	5633306	50633306	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	16135029	52308831	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
631543	Bp83	Blood pressure QTL 83	5.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	44139558	52308831	Rat

Markers in Region

RH140699

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	42,661,490 - 42,661,671 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	48,430,422 - 48,430,602	NCBI	Rnor6.0
Rnor_5.0	12	50,212,927 - 50,213,107	UniSTS	Rnor5.0
RGSC_v3.4	12	43,695,684 - 43,695,864	UniSTS	RGSC3.4
Celera	12	44,264,614 - 44,264,794	UniSTS
Cytogenetic Map	12	q16	UniSTS

BI275132

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	42,677,918 - 42,678,138 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	48,446,848 - 48,447,067	NCBI	Rnor6.0
Rnor_5.0	12	50,229,353 - 50,229,572	UniSTS	Rnor5.0
RGSC_v3.4	12	43,712,110 - 43,712,329	UniSTS	RGSC3.4
Celera	12	44,281,040 - 44,281,259	UniSTS
Cytogenetic Map	12	q16	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001427479	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006221382	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249511	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249512	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008760703	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090197	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090199	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271403	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000044751 ⟹ ENSRNOP00000039607

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	48,296,944 - 48,343,812 (+)	Ensembl
mRatBN7.2 Ensembl	12	42,641,555 - 42,683,274 (+)	Ensembl
Rnor_6.0 Ensembl	12	48,403,797 - 48,446,977 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094762 ⟹ ENSRNOP00000094416

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	48,281,756 - 48,343,812 (+)	Ensembl
mRatBN7.2 Ensembl	12	42,621,196 - 42,683,274 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000106254 ⟹ ENSRNOP00000093097

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	48,281,756 - 48,343,812 (+)	Ensembl
mRatBN7.2 Ensembl	12	42,621,196 - 42,683,274 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114426 ⟹ ENSRNOP00000084683

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	48,281,756 - 48,343,812 (+)	Ensembl
mRatBN7.2 Ensembl	12	42,621,135 - 42,683,274 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000156108 ⟹ ENSRNOP00000108776

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	48,302,158 - 48,338,791 (+)	Ensembl

RefSeq Acc Id:

NM_001427479 ⟹ NP_001414408

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	48,281,756 - 48,343,812 (+)	NCBI

RefSeq Acc Id:

XM_006249511 ⟹ XP_006249573

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	48,311,419 - 48,343,812 (+)	NCBI
mRatBN7.2	12	42,655,451 - 42,683,262 (+)	NCBI
Rnor_6.0	12	48,424,866 - 48,447,964 (+)	NCBI
Rnor_5.0	12	50,186,534 - 50,230,469 (+)	NCBI

Sequence:

show sequence

CAGCAGAGCACTCCTTCATTAAATAATTAAAAAAAAAAAAAAGCCAACTTCCTTTCCCACGCCT
ACTGAAAGGCAGGATAGTACAGGCAGGCGGTATCTCTGGAGTGGGAGTCACCGGGCAGAGGAGG
GAGTAATGTTACCCTCTCCCCACCCTCCCCCACAACCACCCCTGGGCCCAGAGCCTGTAAACCA
CCTGGCAAAGATAGAAACTCGGAATTCCTGAGGGCTGTGGTGTTGCTCAGGCACAATCGCTGCA
GTTTCTCAAGAGCCAGCCCTTAAATGCCTCAAGGGTTTCATCACGATCTGAGAGACCCTTCTGA
TAAGACTCTGTAACCGTGGCGCCAGTGTATCAGTTCACTGCTAGGATGGGCAAAACAGAACTGG
ATTGAAGCAGTTTGTAAAGTGGCAGCAGCACAAAAGGTAGACAGACAGACAGACATACAGACAG
ACAGAAGTCTGAGTGAACAGTGAGACTGGGGGACCTCCCATCTCCTGTTACCCAGGACAGAAGC
CTGGTATGGGCTGTCGCTGACTGCTTGCCGGCTCTCTGCTGCATCCCCACTACCCCAAGAGCTT
CTGTAGTTGTGGAGTTACCGCCACCCCATGCCTGTGTCCTCTAGAATCCAGCCATGACTGAAGA
GTGCCCCCCCAGACAGGCTGCAAACCCCTCCCCACCACAGACCCCGAGGCTGGTGTCAGGCCAG
CAGGTCTGCTAGACAAGGAAACTGAGGGAAGACTGCATACACAGGGCAGACACTGACTCGGTGT
CTTCTCTTCCCCACTCAGCAAAAGCTGTACAATCGGGATGGTCCTTCGACTGTGGAGCGACACC
AAGATCCACCTTGATGGGGACGGGGGGTTCAGTGTGAGCACGGCGGGCAGGATGCACATATTCA
AGCCGGTGTCTGTCCAGGCCATGTGGTCTGCCTTGCAAGTGCTTCACAAGGCCTGTGAAGTGGC
TCGGAGACATAACTACTTCCCGGGGGGAGTGGCACTCATCTGGGCCACCTACTATGAGAGCTGC
ATCAGCTCGGAGCAGAGCTGCATCAATGAATGGAACGCCATGCAGGACCTGGAGTCCACGAGGC
CCGACTCCCCCGCGCTGTTCGTGGACAAGCCGACAGAAGGAGAAAGAACTGAGCGTCTCATTAA
AGCCAAACTCCGGAGTATCATGATGAGCCAGGACCTTGAGAATGTGACTTCTAAGGAAATCCGA
AATGAGCTGGAGAAGCAAATGAACTGCAACCTGAAAGAGTTCAAGGAGTTCATCGATAACGAGA
TGCTGCTCATCTTGGGCCAGATGGACAAGCCCTCCCTTATCTTTGACCATCTTTATCTTGGCTC
CGAGTGGAATGCATCCAATCTGGAGGAGCTGCAGGGCTCAGGGGTCGACTACATTTTAAATGTC
ACTAGAGAAATCGACAATTTTTTCCCTGGCCTGTTTGCATACCATAACATCCGAGTATATGACG
AGGAGACCACGGACCTTCTTGCCCACTGGAATGAGGCCTATCAGTTCATAAACAAAGCGAAAAG
GAACCATTCCAAGTGCCTGGTCCATTGCAAGATGGGCGTGAGCCGGTCTGCATCCACGGTCATA
GCGTACGCCATGAAGGAGTTTGGCTGGCCCCTGGAGAAAGCGTTTAACTATGTGAAACAGAAGC
GCAGCATCACGCGGCCCAACGCAGGCTTTATGAGGCAGCTGTCGGAGTATGAAGGTATCCTGGA
TGCAAGCAAACAGCGACATAACAAACTGTGGCGCCAGCAGCCGGCAGATGACACCATAGCAGAG
CCCAGTGAGTTCTTGCCAGAGACCTTGGATGGCGCCCTGGATACTCAGCTGCCCTGTTTGGAAG
ATGCCACCCACCCCGGGCTCCCGAGAAGCCTGCCCTCGGGAGGACCCTCTCTCCCCTGTTGTTT
CCGAAGACTCTCGGACCCCCTCCTCCTTCCCCACCGTGATGGTGCGGGTGGCCTGGTCCACTTA
GAAGACCTTGAGAGGGATGCTCTGTTAGAGGATGAGGCTCAGCCAGTGGAGGTGCGCAAGCTGG
TCCCGAGTTCCCAGGAAGGTGACAGGCTGTGTGAAAAGGATGTAAAGAGGAAACTGGAGTTTGG
GAGCCCCAAAGCCCGCAGCGGCTCCTTGCCTCAGGTGGAGGAGCTGGAGAAGGATGGCAGCCCA
AGACCGGGGAGGTGGAGGCGGGCCTCCACGCAGCTGGAGAGAGGTTTGCTTGACCAGGAAAACC
TAAATAACAACAACAGCAAGAGGAGCTGTCCCGATGACTTTGAGCGTGATGCGGTGTTTGGGAT
CCTCAGCAAAGTGAAGCCTCCCTATACATCCTGTGCCGACTGCATGTACCCAGCAGCTGGGGCT
CCTGAGGCCTTCATGGAGCGGCATGAAGACCCCAGCTCCTCTGCCATCTGCACCCAGCCGACCT
TCCTCCCCCACGTCACGTCTTCCCCAATGGCCCACACGAGCAATAGGTCCCGAGCTCCGGAGAG
GCCAACCTCAGGTCCAGCTAACACCTCTCCATTCCTACTACCAGCGGGCTCCAGGAAGCCAGAT
GTCAGTGGTTCTGGAGCCGGGGTTGCCCCGGAACCACCAGCAAGCCTTCCAGAGCCTTCCAGAG
AGACCTCGAAAGCCCTTCAGAAATCTCTCCTGTCGAAGAATTCCCACTGTGATAAGAACGCAGC
CAATACGGAGGCGGCGGCAAAGGAAGAACTGTCGACCAAGAAAGATCCGAAGCCCTCAAAGGAC
CTGAGGCTCCTGTTCAGTCAAGAGGGGGAGAAGCCGACCGCCAATAGCTACCTGATGCAACATC
AGGAGTCCATTATCCAGTTGCAGAAGGCAGGCCTGGTCCGAAAGCACACCAAAGAGCTGGAGAG
GTTGAAGAGCCTGCCTTCAGACTCACCATCTACTTGCCGGGACAGTGCCGCCAGCAGGCTGGAG
GCCAGCATCCCCGAGGAGGGTCAGGAGCCTGCACACCCAGCCCTAGACAGCCAAGCTGGAACTG
AAGAGAAGCCTGTGGGCGGAGCCTCACAGAAGAGCCCTCCGCCTACCCTCCTCCTCCGCCTAGA
TCACACCAGTAAAGACTTCTCTAAAGACTTCCTGAAGTCCGCGTGCTACACTCCCACCCCCTCC
TCCATCAGCTCCAACCTGACCCGGAGCTCCAGCAGCGACAGCATCCACAGTGTCCGAGGGAAGC
CAGGGCTGGTGAAGCAGCGGGCGCAGGAGATCGAGACGCGGCTCCGCCTGGCCGGTCTCACTGT
GTCCTCCCCACTGAAACGTTCCCATTCCCTCGCCAAGCTGGGAAGTCTCAACTTCTCCACGGAG
GACCTGTCCAGTGAGGCTGACACGTCAACCATCGCCGACTCACAGGATGCCAAGTGCACTCTCT
CTTCCTTCTTGCCCGAACCCCAGGCCGCACCTAGGAACCCCTCTGCGACCTCCAAACCATCAGG
GAAATCCGCCCCAGAGAACTTGAAAATCCCAGTGAGGGTGAACAAAAGCTGACTAGCTTCCAGC
TCTGCGAGGTCTTCATAATGTCTTGATCCGCTCTCGTGTCTTGATTTGTGTTAACGACTTCAGC
CTTCTGAGCTTTCCCCACCTAGAGCCTGTGAGGGGGAACACCCAGGGGTGGGGCCTGGGCAACC
CGGGAACTGTCAGCCCGGAGTACCGTTCAGATGCATACACACAGGCTGGGGCTTTGTCTCAGTT
GTTGAGAGTGTGTACCTGACACGCGCCAAGCCCTCGGTTTGATTCCCCAGCAGCCCATAAAACC
AGACAAGGCTGCATACACCCACATCCCAACACTGGAGGTGGAAGCAGAAGGATTAGAAGTTCAA
AGTCATCTTCAGCTACTTGGTGAGTTTTAGGCCAGCCTGGCAGAGAGAGTGAGAGAAAAAAAAA
ACAAAAAAAACTATGTGTGTACATACAAAATACTCAGTTTGCAACGAGTAAAGGAGCCACAGTG
GTGAGGTCCCCGCTGCCCATGTTCCCGGCTCAATCCGGTCCTCGAGGGAGAATCCTCCGAGGAC
AACACAAGGCCTACCTCTCCGCTCACTGTGCATTTCATTTATAAAATAGTAATGACCGAGGCTC
GATCCGAGGAACAATGCTGTGTCCAGAAGGGTTTTTCCAAGAGAATTGTGGGGGGTTTTGGGTT
TGGTTTGTTTTATTCTTTTGAGGGTGGTGACCCGCAGAAGCATCAAGACTTTGAACCTGACTAT
CCCAAGAACAGTGAGGCAATATCATCAGAGGAAGGCACTTAGTGGCAGCGCCCGTTTAACAGTC
CTGGTGCCCATGGGCGGAGGCAGGGGGGTCCTCAGCTGCTGGCTTCAAGCTTACGTCACCCAAT
CACAGAGAAGGGCACTGCTGAAGGGCACTGCTGAGCCTTGTCTGCTGCTAACAAGGCATCCTGT
TTGGAATTCAGACCACCTCCGGACCTCAGGACATGAGGTCGTGGATCTGGGATGTGGTTCATCC
CGCTGAGACACTGTGACCCCCACCCCCAACCCCACCCCCACTTCCACCCAAGGCTCTCATTCAG
TGCCATCTCCACATTTGTTGAAAGGAAAGGCAGGTCAGCAACGGGTACTTTCTTACAAGCTGCT
CCCCAGGAGTCACTCTGAGAGGAGAGAGTCTGTTAAAAAAAGCTTCACAGATGTTTATGAAGTG
TCCCTTCTCATGGGGAGA

hide sequence

RefSeq Acc Id:

XM_039090197 ⟹ XP_038946125

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	48,291,657 - 48,343,812 (+)	NCBI
mRatBN7.2	12	42,631,104 - 42,683,262 (+)	NCBI

RefSeq Acc Id:

XM_039090199 ⟹ XP_038946127

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	48,303,240 - 48,343,812 (+)	NCBI
mRatBN7.2	12	42,642,744 - 42,683,262 (+)	NCBI

RefSeq Acc Id:

XM_063271403 ⟹ XP_063127473

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	48,290,387 - 48,343,812 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001414408	(Get FASTA)	NCBI Sequence Viewer
	XP_006249573	(Get FASTA)	NCBI Sequence Viewer
	XP_038946125	(Get FASTA)	NCBI Sequence Viewer
	XP_038946127	(Get FASTA)	NCBI Sequence Viewer
	XP_063127473	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM13958	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000039607
	ENSRNOP00000039607.6
	ENSRNOP00000084683.2
	ENSRNOP00000093097.1
	ENSRNOP00000094416
	ENSRNOP00000094416.2
	ENSRNOP00000108776
	ENSRNOP00000108776.1

RefSeq Acc Id:	XP_006249573 ⟸ XM_006249511
- Peptide Label:	isoform X3
- UniProtKB:	F1LWM1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVLRLWSDTKIHLDGDGGFSVSTAGRMHIFKPVSVQAMWSALQVLHKACEVARRHNYFPGGVAL IWATYYESCISSEQSCINEWNAMQDLESTRPDSPALFVDKPTEGERTERLIKAKLRSIMMSQDL ENVTSKEIRNELEKQMNCNLKEFKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQG SGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYQFINKAKRNHSKCLVHCKMG VSRSASTVIAYAMKEFGWPLEKAFNYVKQKRSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQ QPADDTIAEPSEFLPETLDGALDTQLPCLEDATHPGLPRSLPSGGPSLPCCFRRLSDPLLLPHR DGAGGLVHLEDLERDALLEDEAQPVEVRKLVPSSQEGDRLCEKDVKRKLEFGSPKARSGSLPQV EELEKDGSPRPGRWRRASTQLERGLLDQENLNNNNSKRSCPDDFERDAVFGILSKVKPPYTSCA DCMYPAAGAPEAFMERHEDPSSSAICTQPTFLPHVTSSPMAHTSNRSRAPERPTSGPANTSPFL LPAGSRKPDVSGSGAGVAPEPPASLPEPSRETSKALQKSLLSKNSHCDKNAANTEAAAKEELST KKDPKPSKDLRLLFSQEGEKPTANSYLMQHQESIIQLQKAGLVRKHTKELERLKSLPSDSPSTC RDSAASRLEASIPEEGQEPAHPALDSQAGTEEKPVGGASQKSPPPTLLLRLDHTSKDFSKDFLK SACYTPTPSSISSNLTRSSSSDSIHSVRGKPGLVKQRAQEIETRLRLAGLTVSSPLKRSHSLAK LGSLNFSTEDLSSEADTSTIADSQDAKCTLSSFLPEPQAAPRNPSATSKPSGKSAPENLKIPVR VNKS hide sequence

Ensembl Acc Id:

ENSRNOP00000039607 ⟸ ENSRNOT00000044751

RefSeq Acc Id:	XP_038946125 ⟸ XM_039090197
- Peptide Label:	isoform X1
- UniProtKB:	F1LWM1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038946127 ⟸ XM_039090199
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6A2G7 (UniProtKB/TrEMBL), F1LWM1 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000084683 ⟸ ENSRNOT00000114426

Ensembl Acc Id:

ENSRNOP00000093097 ⟸ ENSRNOT00000106254

Ensembl Acc Id:

ENSRNOP00000094416 ⟸ ENSRNOT00000094762

RefSeq Acc Id:	NP_001414408 ⟸ NM_001427479
- UniProtKB:	A0A8I6B0P9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063127473 ⟸ XM_063271403
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6A2G7 (UniProtKB/TrEMBL), F1LWM1 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000108776 ⟸ ENSRNOT00000156108

Protein Domains

DEK-C Tyrosine specific protein phosphatases Tyrosine-protein phosphatase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LWM1-F1-model_v2	AlphaFold	F1LWM1	1-1032	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306038	AgrOrtholog
BioCyc Gene	G2FUF-18934	BioCyc
Ensembl Genes	ENSRNOG00000000695	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000044751	ENTREZGENE
	ENSRNOT00000044751.8	UniProtKB/TrEMBL
	ENSRNOT00000094762	ENTREZGENE
	ENSRNOT00000094762.2	UniProtKB/TrEMBL
	ENSRNOT00000106254.2	UniProtKB/TrEMBL
	ENSRNOT00000114426.2	UniProtKB/TrEMBL
	ENSRNOT00000156108	ENTREZGENE
	ENSRNOT00000156108.1	UniProtKB/TrEMBL
Gene3D-CATH	3.90.190.10	UniProtKB/TrEMBL
	Homeodomain-like	UniProtKB/TrEMBL
InterPro	DEK_C	UniProtKB/TrEMBL
	Dual-sp_phosphatase_cat-dom	UniProtKB/TrEMBL
	Dual-sp_phosphatase_subgr_cat	UniProtKB/TrEMBL
	Phosphatase_SSH-like	UniProtKB/TrEMBL
	Prot-tyrosine_phosphatase-like	UniProtKB/TrEMBL
	SSH-N	UniProtKB/TrEMBL
	Tyr/Dual-specificity_Pase	UniProtKB/TrEMBL
	Tyr_Pase_AS	UniProtKB/TrEMBL
NCBI Gene	304580	ENTREZGENE
PANTHER	PTHR45864	UniProtKB/TrEMBL
	PTHR45864:SF5	UniProtKB/TrEMBL
Pfam	DEK_C	UniProtKB/TrEMBL
	DSPc	UniProtKB/TrEMBL
	PH_SSH1-like_1st	UniProtKB/TrEMBL
PhenoGen	Ssh1	PhenoGen
PROSITE	DEK_C	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_1	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_2	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_DUAL	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000000695	RatGTEx
SMART	DSPc	UniProtKB/TrEMBL
Superfamily-SCOP	DEK C-terminal domain	UniProtKB/TrEMBL
	SSF52799	UniProtKB/TrEMBL
UniProt	A0A8I6A2G7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AIB0_RAT	UniProtKB/TrEMBL
	A0A8I6B0P9	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0M1D8_RAT	UniProtKB/TrEMBL
	F1LWM1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-03-20	Ssh1	slingshot protein phosphatase 1	Ssh1	slingshot homolog 1 (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-03	Ssh1	slingshot homolog 1 (Drosophila)	Coro1c_predicted	coronin, actin binding protein 1C (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Coro1c_predicted	coronin, actin binding protein 1C (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - PID (archival)