Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,1-dichloroethene | decreases expression | ISO | Aifm3 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of AIFM3 mRNA | CTD | PMID:26682919 | 1-Hydroxypyrene | decreases expression | ISO | AIFM3 (Homo sapiens) | 6480464 | 1-hydroxypyrene results in decreased expression of AIFM3 mRNA | CTD | PMID:21854004 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of AIFM3 mRNA | CTD | PMID:32145629 | 1H-pyrazole | decreases expression | ISO | Aifm3 (Mus musculus) | 6480464 | pyrazole results in decreased expression of AIFM3 mRNA | CTD | PMID:17945193 | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:27291303 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Aifm3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of AIFM3 mRNA | CTD | PMID:33956508 | 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one | increases expression | ISO | AIFM3 (Homo sapiens) | 6480464 | buprofezin results in increased expression of AIFM3 mRNA | CTD | PMID:36287832 | 4,4'-sulfonyldiphenol | affects methylation | ISO | Aifm3 (Mus musculus) | 6480464 | bisphenol S affects the methylation of AIFM3 gene | CTD | PMID:31683443 | 4-hydroxyphenyl retinamide | increases expression | ISO | Aifm3 (Mus musculus) | 6480464 | Fenretinide results in increased expression of AIFM3 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of AIFM3 mRNA | CTD | PMID:24780913 | aristolochic acid A | increases expression | ISO | AIFM3 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of AIFM3 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | increases methylation | ISO | AIFM3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of AIFM3 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | AIFM3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of AIFM3 5' UTR and Benzo(a)pyrene affects the methylation of AIFM3 intron | CTD | PMID:27901495 and PMID:30157460 | benzo[b]fluoranthene | increases expression | ISO | Aifm3 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of AIFM3 mRNA | CTD | PMID:26377693 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of AIFM3 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | Aifm3 (Mus musculus) | 6480464 | bisphenol A results in increased expression of AIFM3 mRNA | CTD | PMID:33221593 | buprofezin | increases expression | ISO | AIFM3 (Homo sapiens) | 6480464 | buprofezin results in increased expression of AIFM3 mRNA | CTD | PMID:36287832 | butanal | decreases expression | ISO | AIFM3 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of AIFM3 mRNA | CTD | PMID:26079696 | cadmium atom | multiple interactions | ISO | Aifm3 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of AIFM3 mRNA | CTD | PMID:37325564 | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of AIFM3 promoter | CTD | PMID:22457795 | cadmium dichloride | multiple interactions | ISO | Aifm3 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of AIFM3 mRNA | CTD | PMID:37325564 | camptothecin | decreases response to substance | ISO | AIFM3 (Homo sapiens) | 6480464 | AIFM3 mRNA results in decreased susceptibility to Camptothecin | CTD | PMID:25269479 | carbon nanotube | increases expression | ISO | Aifm3 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in increased expression of AIFM3 mRNA | CTD | PMID:25554681 | carbon nanotube | decreases expression | ISO | Aifm3 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | copper(II) sulfate | decreases expression | ISO | AIFM3 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of AIFM3 mRNA | CTD | PMID:19549813 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of AIFM3 mRNA | CTD | PMID:26577399 and PMID:27523638 | cyclosporin A | decreases expression | ISO | AIFM3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of AIFM3 mRNA | CTD | PMID:25562108 | diazinon | increases methylation | ISO | AIFM3 (Homo sapiens) | 6480464 | Diazinon results in increased methylation of AIFM3 gene | CTD | PMID:22964155 | dorsomorphin | multiple interactions | ISO | AIFM3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of AIFM3 mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of AIFM3 mRNA | CTD | PMID:32289291 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of AIFM3 mRNA | CTD | PMID:29391264 | ethylparaben | decreases expression | ISO | AIFM3 (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in decreased expression of AIFM3 mRNA | CTD | PMID:37690743 | furan | decreases expression | ISO | Aifm3 (Mus musculus) | 6480464 | furan results in decreased expression of AIFM3 mRNA | CTD | PMID:24183702 and PMID:37517673 | inulin | multiple interactions | ISO | Aifm3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of AIFM3 mRNA | CTD | PMID:36331819 | methylmercury chloride | decreases expression | ISO | AIFM3 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of AIFM3 mRNA | CTD | PMID:28001369 | mono(2-ethylhexyl) phthalate | increases expression | ISO | Aifm3 (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate results in increased expression of AIFM3 mRNA | CTD | PMID:22401849 | monosodium L-glutamate | increases expression | ISO | Aifm3 (Mus musculus) | 6480464 | Sodium Glutamate results in increased expression of AIFM3 mRNA | CTD | PMID:22078008 | N-methyl-4-phenylpyridinium | increases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of AIFM3 mRNA | CTD | PMID:28801915 | N-nitrosodiethylamine | decreases expression | ISO | Aifm3 (Mus musculus) | 6480464 | Diethylnitrosamine results in decreased expression of AIFM3 mRNA | CTD | PMID:24535843 | ozone | multiple interactions | ISO | Aifm3 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of AIFM3 mRNA | CTD | PMID:34911549 | ozone | multiple interactions | ISO | AIFM3 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of AIFM3 mRNA | CTD | PMID:35430440 | ozone | increases expression | ISO | Aifm3 (Mus musculus) | 6480464 | Ozone results in increased expression of AIFM3 mRNA | CTD | PMID:33026818 | pentanal | decreases expression | ISO | AIFM3 (Homo sapiens) | 6480464 | pentanal results in decreased expression of AIFM3 mRNA | CTD | PMID:26079696 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Aifm3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of AIFM3 mRNA | CTD | PMID:36331819 | phenobarbital | decreases expression | ISO | Aifm3 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of AIFM3 mRNA | CTD | PMID:19482888 | phenobarbital | multiple interactions | ISO | Aifm3 (Mus musculus) | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of AIFM3 mRNA] | CTD | PMID:19482888 | pinostrobin | increases expression | ISO | AIFM3 (Homo sapiens) | 6480464 | pinostrobin results in increased expression of AIFM3 mRNA | CTD | PMID:37777166 | pioglitazone | multiple interactions | ISO | Aifm3 (Mus musculus) | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AIFM3 mRNA | CTD | PMID:27935865 | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Aifm3 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of AIFM3 mRNA | CTD | PMID:28903501 | SB 431542 | multiple interactions | ISO | AIFM3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of AIFM3 mRNA | CTD | PMID:27188386 | sodium arsenite | increases expression | ISO | Aifm3 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of AIFM3 mRNA | CTD | PMID:37682722 | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of AIFM3 mRNA | CTD | PMID:19281266 | tetrachloromethane | decreases expression | ISO | Aifm3 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of AIFM3 mRNA | CTD | PMID:31919559 | tetraphene | increases expression | ISO | Aifm3 (Mus musculus) | 6480464 | benz(a)anthracene results in increased expression of AIFM3 mRNA | CTD | PMID:26377693 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of AIFM3 mRNA | CTD | PMID:33387578 | trichostatin A | decreases expression | ISO | AIFM3 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of AIFM3 mRNA | CTD | PMID:24935251 | urethane | decreases expression | ISO | AIFM3 (Homo sapiens) | 6480464 | Urethane results in decreased expression of AIFM3 mRNA | CTD | PMID:28818685 | valproic acid | increases methylation | ISO | AIFM3 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of AIFM3 gene | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | AIFM3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of AIFM3 mRNA | CTD | PMID:23179753 and PMID:26272509 | valproic acid | multiple interactions | ISO | AIFM3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of AIFM3 mRNA | CTD | PMID:27188386 | |